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Arnold, Nicola, Beattie, David, Bradley, Michelle, Brearley, Andrew, Brown, Lyndon, Charlton, Steven J, Fairhurst, Robin A, Farr, David, Fozard, John, Fullerton, Joe, Gosling, Martin, Hatto, Julia, Janus, Diana, Jones, Darryl, Jordan, Lynne, Lewis, Christine, Maas, Janet, McCarthy, Clive, Mercer, Mark, Oakman, Helen, Press, Neil, Profit, Rachel, Schuerch, Friedrich, Sykes, David, Taylor, Roger J, Trifilieff, Alexandre and Tuffnell, Andrew (2014) The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1- hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist. Bioorganic and Medicinal Chemistry Letters, 24 (17). pp. 4341-4347. ISSN 0960-894X

Porter, David W, Bradley, Michelle, Brown, Zarin, Charlton, Steven J, Cox, Brian, Hunt, Peter, Janus, Diana, Lewis, Sarah, Oakley, Paul, O'Connor, Des, Reilly, John, Smith, Nichola and Press, Neil J (2014) The discovery of potent, orally bioavailable pyrimidine-5-carbonitrile-6-alkyl CXCR2 receptor antagonists. Bioorganic and Medicinal Chemistry Letters, 24 (15). pp. 3285-3290. ISSN 0960-894X

McKeown, Stephen C, Charlton, Steven J, Cox, Brian, Fitch, Helen, Howson, Christopher D, Leblanc, Catherine, Meyer, Arndt, Rosethorne, Elizabeth M and Stanley, Emily (2014) Identification of novel IP receptor agonists using historical ligand biased chemical arrays. Bioorganic and Medicinal Chemistry Letters, 24 (10). pp. 2247-2250. ISSN 0960-894X

Porter, David W, Bradley, Michelle, Brown, Zarin, Canova, Riccardo, Charlton, Steven, Cox, Brian, Hunt, Peter, Kolarik, David, Lewis, Sarah, O'Connor, Des, Reilly, John, Spanka, Carsten, Tedaldia, Lauren, Watson, Simon J, Wermuth, Roland and Press, Neil J (2014) The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists. Bioorganic and Medicinal Chemistry Letters, 24 (1). pp. 72-76. ISSN 0960-894X

Amin, Jahangir, Puglisi, Antonio, Clarke, James, Milton, John, Wang, Minghua, Paranal, Ronald M, Bradner, James E and Spencer, John (2013) A cyclodextrin-capped histone deacetylase inhibitor. Bioorganic and Medicinal Chemistry Letters, 23 (11). pp. 3346-3348. ISSN 0960-894X

Bruce, Ian, Akhlaq, Mohammed, Bloomfield, Graham C, Budd, Emma, Cox, Brian, Cuenoud, Bernard, Finan, Peter, Gedeck, Peter, Hatto, Julia, Hayler, Judy F, Head, Denise, Keller, Thomas, Kirman, Louise, Leblanc, Catherine, Le Grand, Darren, McCarthy, Clive, O'Connor, Desmond, Owen, Charles, Oza, Mrinalini S, Pilgrim, Gaynor, Press, Nicola E, Sviridenko, Lilya and Whitehead, Lewis (2012) Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway. Bioorganic and Medicinal Chemistry Letters, 22 (17). pp. 5445-5450. ISSN 0960-894X

Hunt, Thomas, Atherton-Watson, Hazel C, Axford, Jake, Collingwood, Stephen P, Coote, Kevin J, Cox, Brian, Czarnecki, Sarah, Danahay, Henry, Devereux, Nick, Howsham, Catherine, Hunt, Peter, Paddock, Victoria, Paisley, Derek and Young, Alice (2012) Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: Quaternary amines. Bioorganic and Medicinal Chemistry Letters, 22 (2). pp. 929-932. ISSN 0960-894X

Masood, M Abid, Bazin, Marc, Bunnage, Mark E, Calabrese, Andrew, Cox, Mark, Fancy, Sally-Ann, Farrant, Elizabeth, Pearce, David W, Perez, Manuel, Hitzel, Laure and Peakman, Torren (2012) Lead diversification 2: application to P38, gMTP and lead compounds. Bioorganic and Medicinal Chemistry Letters, 22 (2). pp. 1255-1262. ISSN 0960-894X

Paradowski, Michael (2011) Challenges of drug discovery in novel target space. The Discovery and Evaluation of PF-3893787: A Novel Histamine H4 Receptor Antagonist. Bioorganic and Medicinal Chemistry Letters, 21. pp. 6596-6602. ISSN 0960894X

Thewlis, Kevin M, Aldegheri, Laura, Harries, Mark H, Mookherjee, Claudette, Oliosi, Beatrice and Ward, Simon E (2010) N-Substituted pyrrolidines and tetrahydrofurans as novel AMPAR positive modulators. Bioorganic and Medicinal Chemistry Letters, 20 (23). pp. 7116-7119. ISSN 0960-894X

Li, Xianfeng, Zhang, Yong-Kang, Liu, Yang, Ding, Charles Z, Zhou, Yasheen, Li, Qun, Plattner, Jacob J, Baker, Stephen J, Zhang, Suoming, Kazmierski, Wieslaw M, Wright, Lois L, Smith, Gary K, Grimes, Richard M, Crosby, Renae M, Creech, Katrina L, Carballo, Luz H, Slater, Martin J, Jarvest, Richard L, Thommes, Pia, Hubbard, Julia A, Convery, Maire A, Nassau, Pamela M, McDowell, William, Skarzynski, Tadeusz J, Qian, Xuelei, Fan, Dazhong, Liao, Liang, Ni, Zhi-Jie, Pennicott, Lewis E, Zou, Wuxin and Wright, Jon (2010) Novel macrocyclic HCV NS3 protease inhibitors derived from α-amino cyclic boronates. Bioorganic and Medicinal Chemistry Letters, 20 (19). pp. 5695-5700. ISSN 0960-894X

Beattie, David, Bradley, Michelle, Brearley, Andrew, Charlton, Steven J, Cuenoud, Bernard M, Fairhurst, Robin A, Gedeck, Peter, Gosling, Martin, Janus, Diana, Jones, Darryl, Lewis, Christine, McCarthy, Clive, Oakman, Helen, Stringer, Rowan, Taylor, Roger J and Tuffnell, Andrew (2010) A physical properties based approach for the exploration of a 4-hydroxybenzothiazolone series of β2-adrenoceptor agonists as inhaled long-acting bronchodilators. Bioorganic and Medicinal Chemistry Letters, 20 (17). pp. 5302-5307. ISSN 0960-894X

Li, Xianfeng, Zhang, Yong-Kang, Liu, Yang, Ding, Charles Z, Li, Qun, Zhou, Yasheen, Plattner, Jacob J, Baker, Stephen J, Qian, Xuelei, Fan, Dazhong, Liao, Liang, Ni, Zhi-Jie, White, Gemma V, Mordaunt, Jackie E, Lazarides, Linos X, Slater, Martin J, Jarvest, Richard L, Thommes, Pia, Ellis, Malcolm, Edge, Colin M, Hubbard, Julia A, Somers, Don, Rowland, Paul, Nassau, Pamela, McDowell, Bill, Skarzynski, Tadeusz J, Kazmierski, Wieslaw M, Grimes, Richard M, Wright, Lois L., Smith, Gary K, Zou, Wuxin, Wright, Jon and Pennicott, Lewis E (2010) Synthesis and evaluation of novel α-amino cyclic boronates as inhibitors of HCV NS3 protease. Bioorganic and Medicinal Chemistry Letters, 20 (12). pp. 3550-3556. ISSN 0960-894X

Beattie, David, Brearley, Andrew, Brown, Zarin, Charlton, Steven J, Cox, Brian, Fairhurst, Robin A, Fozard, John R, Gedeck, Peter, Kirkham, Paul, Meja, Koremu, Nanson, Lana, Neef, James, Oakman, Helen, Spooner, Gillian, Taylor, Roger J, Turner, Robert J, West, Ryan and Woodward, Hannah (2010) Synthesis and evaluation of two series of 4′-aza-carbocyclic nucleosides as adenosine A2A receptor agonists. Bioorganic and Medicinal Chemistry Letters, 20 (3). pp. 1219-1224. ISSN 0960-894X

McGuigan, Christopher, Derudas, Marco, Quintiliani, Maurizio, Andrei, Graciela, Snoeck, Robert, Henson, Geoffrey and Balzarini, Jan (2009) 2′-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorganic and Medicinal Chemistry Letters, 19 (22). pp. 6264-6267. ISSN 0960-894X

Sandham, David A, Adcock, Claire, Bala, Kamlesh, Barker, Lucy, Brown, Zarin, Dubois, Gerald, Budd, David, Cox, Brian, Fairhurst, Robin A, Furegati, Markus, Leblanc, Catherine, Manini, Jodie, Profit, Rachael, Reilly, John, Stringer, Rowan, Schmidt, Alfred, Turner, Katharine L, Watson, Simon J, Willis, Jennifer, Williams, Gareth and Wilson, Caroline (2009) 7-Azaindole-3-acetic acid derivatives: potent and selective CRTh2 receptor antagonists. Bioorganic and Medicinal Chemistry Letters, 19 (16). pp. 4794-4798. ISSN 0960-894X

Brown, Alan, Ellis, Dave, Pearce, David, Ralph, Michael and Sciammetta, Nunzio (2009) Aryloxypyrazines as highly selective antagonists of Oxytocin. Bioorganic and Medicinal Chemistry Letters, 19 (10). pp. 2634-2636. ISSN 0960-894X

Owen, Dafydd R, Rodriguez-Lens, Margarita, Corless, Martin D, Gaulier, Steven M, Horne, Valerie A, Kinloch, Ross A, Maw, Graham N, Pearce, David W, Rees, Huw, Ringer, Tracy J, Ryckmans, Thomas and Stammen, Blanda L C (2009) 2,4-Diaminopyridine δ-opioid receptor agonists and their associated hERG pharmacology. Bioorganic and Medicinal Chemistry Letters, 19 (6). pp. 1702-1706. ISSN 0960-894X

Ward, Simon E, Eddershaw, Peter, Flynn, Sean T, Gordon, Laurie, Lovell, Peter J, Moore, Susan H, Scott, Claire M, Smith, Paul W, Thewlis, Kevin M and Wyman, Paul A (2009) Studies on a series of potent, orally bioavailable, 5-HT1 receptor ligands-Part II. Bioorganic and Medicinal Chemistry Letters, 19 (2). pp. 428-432. ISSN 0960-894X

McGuigan, Christopher, Derudas, Marco, Bugert, Joachim J, Andrei, Graciela, Snoeck, Robert and Balzarini, Jan (2008) Successful kinase bypass with new acyclovir phosphoramidate prodrugs. Bioorganic and Medicinal Chemistry Letters, 18 (15). pp. 4364-4367. ISSN 0960-894X

Ward, Simon (2008) Antagonists of the human adenosine A(2A) receptor. Part 1: Discovery and synthesis of thieno[3,2-d] pyrimidine-4-methanone derivatives. Bioorganic and Medicinal Chemistry Letters, 18 (9). pp. 2916-2919. ISSN 0960894X

Sandham, David A, Aldcroft, Clive, Baettig, Urs, Barker, Lucy, Beer, David, Bhalay, Gurdip, Brown, Zarin, Dubois, Gerald, Budd, David, Bidlake, Louise, Campbell, Emma, Cox, Brian, Everatt, Brian, Harrison, David, Leblanc, Catherine J, Manini, Jodie, Profit, Rachael, Stringer, Rowan, Thompson, Katy S, Turner, Katharine L, Tweed, Morris F, Walker, Christopher, Watson, Simon J, Whitebread, Steven, Willis, Jennifer, Williams, Gareth and Wilson, Caroline (2007) 2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists. Bioorganic and Medicinal Chemistry Letters, 17 (15). pp. 4347-4350. ISSN 0960-894X

Wall, Michael D, Oshin, Michael, Chung, Gavin A C, Parkhouse, Tony, Gore, Andrea, Herreros, Esperanza, Cox, Brian, Duncan, Ken, Evans, Brian, Everett, Martin and Mendoza, Alfonso (2007) Evaluation of N-(phenylmethyl)-4-[5-(phenylmethyl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-4-yl]benzamide inhibitors of Mycobacterium tuberculosis growth. Bioorganic and Medicinal Chemistry Letters, 17 (10). pp. 2740-2744. ISSN 0960-894X

Cheung, Kwai-Ming J, Matthews, Thomas P, James, Karen, Rowlands, Martin G, Boxall, Katherine J, Sharp, Swee Y, Maloney, Alison, Roe, S Mark, Prodromou, Chrisostomos, Pearl, Laurence H, Aherne, G Wynne, McDonald, Edward and Workman, Paul (2005) The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors. Bioorganic and Medicinal Chemistry Letters, 15 (14). pp. 3338-3343. ISSN 0960-894X

Streicher, Hans (2004) Synthesis and evaluation as sialidase inhibitors of xylo-configured cyclohexenephosphonates carrying glycerol side-chain mimics. Bioorganic and Medicinal Chemistry Letters, 14 (2). pp. 361-364. ISSN 0960-894X

Streicher, Hansjorg, Schmid, Walther, Wenzl, Irmgard, Fiedler, Christian, Kahlig, Hanspeter and Unger, Frank M (2000) Synthesis and binding to plant lectins of sulfur-containing analogues of beta Gal1,3 alpha GalNAc (T-antigen). Bioorganic and Medicinal Chemistry Letters, 10 (12). pp. 1369-1371. ISSN 0960-894X

Smith, Paul W, Lai, Justine Y Q, Whittington, Andrew R, Cox, Brian, Houston, John G, Stylli, C Harri, Banks, Martyn N and Tiller, Philip R (1994) Synthesis and biological evaluation of a library containing potentially 1600 amides / esters. A strategy for rapid compound generation and screening. Bioorganic and Medicinal Chemistry Letters, 4 (24). pp. 2821-2824. ISSN 0960-894X

Cox, Brian, Hutson, Julie L, Keeling, Suzanne E, Kirk, Barrie E, Srikantha, Anton R P and Watson, Nigel S (1994) The squalestatins: potent inhibitors of squalene synthase, 3-hydroxymethyl derivatives. Bioorganic and Medicinal Chemistry Letters, 4 (16). pp. 1931-1936. ISSN 0960-894X

Watson, Nigel S, Bell, Richard, Chan, Chuen, Cox, Brian, Hutson, Julie L, Keeling, Suzanne E, Kirk, Barrie E, Procopiou, Panayiotis A, Steeples, Ian P and Widdowson, Julia (1993) The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety. Bioorganic and Medicinal Chemistry Letters, 3 (12). pp. 2541-2546. ISSN 0960-894X