Items for Serpell, Louise

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Steele, Oliver George, Stuart, Alexander Cameron, Minkley, Lucy, Shaw, Kira, Bonnar, Orla, Anderle, Silvia, Penn, Andrew Charles, Rusted, Jennifer, Serpell, Louise, Hall, Catherine and King, Sarah (2022) A multi-hit hypothesis for an APOE4-dependent pathophysiological state. Eur J Neurosci. ISSN 0953-816X

Biasetti, Luca, Rey, Stephanie, Fowler, Milena, Ratnayaka, Arjuna, Fennell, Kate, Smith, Catherine, Marshall, Karen, Hall, Catherine, Vargas-Caballero, Mariana, Serpell, Louise and Staras, Kevin (2022) Elevated amyloid beta disrupts the nanoscale organization and function of synaptic vesicle pools in hippocampal neurons. Cerebral Cortex. pp. 1-14. ISSN 1047-3211

Lyu, Chen, Da Vela, Stefano, Al-Hilaly, Youssra, Marshall, Karen E, Thorogate, Richard, Svergun, Dmitri, Serpell, Louise C, Pastore, Annalisa and Hanger, Diane P (2021) The disease associated Tau35 fragment has an increased propensity to aggregate compared to full-length Tau. Frontiers in Molecular Biosciences, 8. a779240 1-13. ISSN 2296-889X

Devonport, Jack, Bodnár, Nikolett, McGown, Andrew, Maina, Mahmoud Bukar, Serpell, Louise C, Kállay, Csilla, Spencer, John and Kostakis, George E (2021) Salpyran: a Cu(II) selective chelator with therapeutic potential. Inorganic Chemistry, 60 (20). pp. 15310-15320. ISSN 0020-1669

Vadukul, Devkee M, Vrancx, Céline, Burguet, Pierre, Contino, Sabrina, Suelves, Nuria, Serpell, Louise C, Quinton, Loïc and Kienlen-Campard, Pascal (2021) An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β. Scientific Reports, 11 (1). a11570 1-17. ISSN 2045-2322

Maina, Mahmoud B, Al-Hilaly, Youssra K, Burra, Gunasekhar, Rickard, Janet E, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2021) Oxidative stress conditions result in trapping of PHF-core tau (297-391) intermediates. Cells, 10 (3). p. 703. ISSN 2073-4409

Burra, Gunasekhar, Maina, Mahmoud B, Serpell, Louise C and Thakur, Ashwani K (2021) Nucleation-dependent aggregation kinetics of yeast Sup35 fragment GNNQQNY. Journal of Molecular Biology, 433 (3). p. 166732. ISSN 0022-2836

Marshall, Karen E, Vadukul, Devkee M, Staras, Kevin and Serpell, Louise C (2020) Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway. Cellular and Molecular Life Sciences, 77. pp. 5031-5043. ISSN 1420-682X

Martins, Pedro M, Navarro, Susanna, Silva, Alexandra, Pinto, Maria F, Sárkány, Zsuzsa, Figueiredo, Francisco, Pereira, Pedro José Barbosa, Pinheiro, Francisca, Bednarikova, Zuzana, Burdukiewicz, Michal, Galzitskaya, Oxana V, Gazova, Zuzana, Gomes, Cláudio M, Pastore, Annalisa, Serpell, Louise C, Skrabana, Rostislav, Smirnovas, Vytautas, Ziaunys, Mantas, Otzen, Daniel E, Ventura, Salvador and Macedo-Ribeiro, Sandra (2020) MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments. Frontiers in Molecular Neuroscience, 13. a582488. ISSN 1662-5099

Oakley, Sebastian S, Maina, Mahmoud B, Marshall, Karen E, Al-Hilaly, Youssra K, Harrington, Charlie R, Wischik, Claude M and Serpell, Louise C (2020) Tau filament self-assembly and structure: tau as a therapeutic target. Frontiers in Neurology, 11. p. 590754. ISSN 1664-2295

Vadukul, Devkee M, Maina, Mahmoud, Franklin, Hannah, Nardecchia, Astrid, Serpell, Louise C and Marshall, Karen E (2020) Internalisation and toxicity of amyloid-β 1-42 are influenced by its conformation and assembly state rather than size. FEBS Letters, 594 (21). pp. 3490-3503. ISSN 0014-5793

Maina, Mahmoud B, Burra, Gunasekhar, Al-Hilaly, Youssra, Mengham, Kurtis, Fennell, Kate and Serpell, Louise C (2020) Metal- and UV- catalyzed oxidation results in trapped amyloid-β intermediates revealing that self-assembly is required for Aβ-induced cytotoxicity. iScience, 23 (10). a101537. ISSN 2589-0042

Ke, Pu Chun, Zhou, Ruhong, Serpell, Louise C, Riek, Roland, Knowles, Tuomas P J, Lashuel, Hilal A, Gazit, Ehud, Hamley, Ian W, Davis, Thomas P, Fändrich, Marcus, Otzen, Daniel Erik, Chapman, Matthew R, Dobson, Christopher M, Eisenberg, David S and Mezzenga, Raffaele (2020) Half a century of amyloids: past, present and future. Chemical Society Reviews, 49 (15). pp. 5473-5509. ISSN 0306-0012

Pollack, Saskia j, Trigg, Jasmine, Khanom, Tahmida, Biasetti, Luca, Marshall, Karen E, Al-Hilaly, Youssra K, Rickard, Janet E, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2020) Paired helical filament-forming region of tau (297–391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells. Journal of Molecular Biology, 432 (17). pp. 4891-4907. ISSN 0022-2836

Habila, Nathan, Kulkarni, Ketav, Lee, Tzong-Hsien, Al-Garawi, Zahraa S, Serpell, Louise C, Aguilar, Marie-Isabel and Del Borgo, Mark P (2020) Transition of nano-architectures through self-assembly of lipidated β3-tripeptide foldamers. Frontiers in Chemistry, 8. p. 217. ISSN 2296-2646

Al‐Hilaly, Youssra K, Foster, Bronwen E, Biasetti, Luca, Lutter, Liisa, Pollack, Saskia J, Rickard, Janet E, Storey, John M D, Harrington, Charles R, Xue, Wei‐Feng, Wischik, Claude M and Serpell, Louise C (2019) Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer’s disease brain. FEBS Letters. pp. 1-7. ISSN 0014-5793

Raulin, Ana-Caroline, Kraft, Lucas, Al-Hilaly, Youssra, Xue, Wei-Feng, McGeehan, John E, Atack, John R and Serpell, Louise (2019) The molecular basis for apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease. Journal of Molecular Biology, 431 (12). pp. 2248-2265. ISSN 0022-2836

Sampani, Stavroula L, Al-Hilaly, Youssra K, Malik, Sharali, Serpell, Louise C and Kostakis, George E (2019) Zinc-dysprosium functionalized amyloid fibrils. Dalton Transactions. ISSN 1477-9226

Fichou, Yann, Al-Hilaly, Youssra K, Devred, François, Smet-Nocca, Caroline, Tsvetkov, Philipp O, Verelst, Joke, Winderickx, Joris, Geukens, Nick, Vanmechelen, Eugeen, Perrotin, Audrey, Serpell, Louise, Hanseeuw, Bernard J, Medina, Miguel, Buée, Luc and Landrieu, Isabelle (2019) The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention? Acta Neuropathologica Communications, 7 (31). pp. 1-17. ISSN 2051-5960

Ruiz-Zamora, Robin Axel, Guillaumé, Simon, Al-Hilaly, Youssra K, Al-Garawi, Zahraa, Rodríguez-Alvarez, Francisco Javier, Zavala-Padilla, Guadalupe, Pérez-Carreón, Julio I, Rodríguez-Ambriz, Sandra L, Herrera, Guillermo A, Becerril-Luján, Baltazar, Ochoa-Leyva, Adrián, Melendez-Zajgla, Jorge, Serpell, Louise and del Pozo-Yauner, Luis (2019) The CDR1 and other regions of immunoglobulin light chains are hot spots for amyloid aggregation. Scientific Reports, 9. a3123. ISSN 2045-2322

Kraft, Lucas, Serpell, Louise C and Atack, John (2019) A biophysical approach to the identification of novel ApoE chemical probes. Biomolecules, 9 (2). 48 1-16. ISSN 2218-273X

Erskine, Elliot, Morris, Ryan J, Schor, Marieke, Earl, Chris, Gillespie, Rachel M C, Bromley, Keith, Sukhodub, Tetyana, Clark, Lauren, Fyfe, Paul, Serpell, Louise C, Stanley-Wall, Nicola R and MacPhee, Cait E (2018) Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA. Molecular Microbiology, 110 (6). pp. 897-913. ISSN 0950-382X

Al-Hilaly, Youssra K, Pollack, Saskia J, Rickard, Janet E, Simpson, Michael, Raulin, Ana-C, Baddeley, Thomas, Schellenberger, Pascale, Storey, John M D, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2018) Cysteine-independent inhibition of alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT). Journal of Molecular Biology, 430 (21). pp. 4119-4131. ISSN 0022-2836

Christofferson, Andrew J, Al-Garawi, Zahraa S, Todorova, Nevena, Turner, Jack, Del Borgo, Mark Pasqualino, Serpell, Louise C, Aguilar, Marie-Isabel and Yarovsky, Irene (2018) Identifying the coiled-coil triple helix structure of β-peptide nanofibers at atomic resolution. ACS Nano, 12 (9). pp. 9101-9109. ISSN 1936-0851

Maina, Mahmoud B, Bailey, Laura J, Doherty, Aidan J and Serpell, Louise C (2018) The involvement of Aβ42 and tau in nucleolar and protein synthesis machinery dysfunction. Frontiers in Cellular Neuroscience, 12 (220). pp. 1-13. ISSN 1662-5102

Maina, Mahmoud B, Bailey, Laura J, Wagih, Sherin, Biasetti, Luca, Pollack, Saskia J, Quinn, James P, Thorpe, Julian R, Doherty, Aidan J and Serpell, Louise C (2018) The involvement of tau in nucleolar transcription and the stress response. Acta Neuropathologica Communications, 6 (70). pp. 1-13. ISSN 2051-5960

Al-Hilaly, Youssra K, Pollack, Saskia J, Vadukul, Devkee, Citossi, Francesca, Rickard, Janet E, Simpson, Michael, Storey, John M D, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2017) Alzheimer's disease-like paired helical filament assembly from truncated tau protein is independent of disulphide cross-linking. Journal of Molecular Biology, 429 (4). pp. 3650-3665. ISSN 0022-2836

Kubánková, Markéta, López-Duarte, Ismael, Bull, James A, Vadukul, Devkee M, Serpell, Louise C, de Saint Victor, Marie, Stride, Eleanor and Kuimova, Marina K (2017) Probing supramolecular protein assembly using covalently attached fluorescent molecular rotors. Biomaterials, 139. pp. 195-201. ISSN 0142-9612

Al-Garawi, Z S, McIntosh, B A, Neill-Hall, D, Hatimy, A A, Sweet, S M, Bagley, M C and Serpell, L C (2017) The amyloid architecture provides a scaffold for enzyme-like catalysts. Nanoscale, 9 (30). pp. 10773-10783. ISSN 2040-3364

Ardoña, Herdeline Ann M, Draper, Emily R, Citossi, Francesca, Wallace, Matthew, Serpell, Louise C, Adams, Dave J and Tovar, John D (2017) Kinetically controlled coassembly of multichromophoric peptide hydrogelators and the impacts on energy transport. Journal of the American Chemical Society, 139 (25). pp. 8685-8692. ISSN 0002-7863

Linke, Reinhold P, Serpell, Louise C, Lottspeich, Friedrich and Toyoda, Mitsuyasu (2017) Cathepsin K as a novel amyloid fibril protein in humans. Amyloid, 24 (1). pp. 68-69. ISSN 1350-6129

Ford, Lenzie, Crossley, Michael, Vadukul, Devkee M, Kemenes, György and Serpell, Louise C (2017) Structure dependent effects of Amyloid-β on long-term memory in Lymnaea stagnalis. FEBS Letters, 591 (9). pp. 1236-1246. ISSN 0014-5793

Vadukul, Devkee M, Gbajumo, Oyinkansola, Marshall, Karen E and Serpell, Louise C (2017) Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid-β 1-42. FEBS Letters, 591 (5). pp. 822-830. ISSN 0014-5793

Colquhoun, Catherine, Draper, Emily R, Schweins, Ralf, Marcello, Marco, Vadukul, Devkee, Serpell, Louise C and Adams, Dave J (2017) Controlling the network type in self-assembled dipeptide hydrogels. Soft Matter, 13 (9). pp. 1914-1919. ISSN 1744-683X

Al-Hilaly, Youssra K, Biasetti, Luca, Brakeman, Ben J, Pollack, Saskia J, Zibaee, Shahin, Abdul-Sada, Alaa, Thorpe, Julian R, Xue, Wei-Feng and Serpell, Louise C (2016) The involvement of dityrosine crosslinking in α-synuclein assembly and deposition in Lewy Bodies in Parkinson’s disease. Scientific Reports, 6. p. 39171. ISSN 2045-2322

Al-Garawi, Zahraa S, Kostakis, Georgios E and Serpell, Louise C (2016) Chemically and thermally stable silica nanowires with a β-sheet peptide core for bionanotechnology. Journal of Nanobiotechnology, 14. p. 79. ISSN 1477-3155

Gallardo, Rodrigo, Ramakers, Meine, De Smet, Frederik, Claes, Filip, Khodaparast, Ladan, Khodaparast, Laleh, Couceiro, José R, Langenberg, Tobias, Siemons, Maxime, Nyström, Sofie, Young, Laurence J, Laine, Romain F, Young, Lydia, Radaelli, Enrico, Benilova, Iryna, Kumar, Manoj, Staes, An, Desager, Matyas, Beerens, Manu, Vandervoort, Petra, Luttun, Aernout, Gevaert, Kris, Bormans, Guy, Dewerchin, Mieke, Van Eldere, Johan, Carmeliet, Peter, Vande Velde, Greetje, Verfaillie, Catherine, Kaminski, Clemens F, De Strooper, Bart, Hammarström, Per, Nilsson, K Peter R, Serpell, Louise, Schymkowitz, Joost and Rousseau, Frederic (2016) De novo design of a biologically active amyloid. Science, 354 (6313). aah4949. ISSN 0036-8075

Sant’Anna, Ricardo, Fernández, Maria Rosario, Batlle, Cristina, Navarro, Susanna, de Groot, Natalia S, Serpell, Louise and Ventura, Salvador (2016) Characterization of amyloid cores in prion domains. Scientific Reports, 6. a34274. ISSN 2045-2322

Marshall, Karen E, Vadukul, Devkee M, Dahal, Liza, Theisen, Alina, Fowler, Milena W, Al-Hilaly, Youssra, Ford, Lenzie, Kemenes, György, Day, Iain J, Staras, Kevin and Serpell, Louise (2016) A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration. Scientific Reports, 6 (1). a30182. ISSN 2045-2322

Joyce, Rebecca E, Williams, Thomas L, Serpell, Louise C and Day, Iain J (2016) Monitoring changes of paramagnetically-shifted 31P signals in phospholipid vesicles. Chemical Physics Letters, 648. pp. 124-129. ISSN 0009-2614

Williams, Thomas L, Serpell, Louise C and Urbanc, Brigita (2016) Stabilization of native amyloid β-protein oligomers by Copper and Hydrogen peroxide Induced Cross-linking of Unmodified Proteins (CHICUP). BBA - Proteins and Proteomics, 1864 (3). pp. 249-259. ISSN 1570-9639

Bukar Maina, Mahmoud, Al-Hilaly, Youssra and Serpell, Louise (2016) Nuclear tau and its potential role in Alzheimer’s disease. Biomolecules, 6 (1). 9 1-20. ISSN 2218-273X

Al-Garawi, Zahraa S, Thorpe, Julian R and Serpell, Louise C (2015) Silica nanowires templated by amyloid-like fibrils. Angewandte Chemie International Edition, 54 (45). pp. 13327-13331. ISSN 1433-7851

Al-Garawi, Zahraa S, Thorpe, Julian R and Serpell, Louise C (2015) Silica nanowires templated by amyloid-like fibrils. Angewandte Chemie, 127 (45). pp. 13525-13529. ISSN 0044-8249

Williams, Thomas L, Urbanc, Brigita, Marshall, Karen E, Vadukul, Devkee M, Jenkins, A Toby A and Serpell, Louise C (2015) Europium as an inhibitor of Amyloid-β(1-42) induced membrane permeation. FEBS Letters, 589 (21). pp. 3228-3236. ISSN 0014-5793

Burgess, Natasha C, Sharp, Thomas H, Thomas, Franziska, Wood, Christopher W, Thomson, Andrew R, Zaccai, Nathan R, Brady, R Leo, Serpell, Louise C and Woolfson, Derek N (2015) Modular design of self-assembling peptide-based nanotubes. Journal of the American Chemical Society, 137 (33). pp. 10554-10562. ISSN 0002-7863

Ford, Lenzie, Crossley, Michael, Williams, Thomas, Thorpe, Julian R, Serpell, Louise C and Kemenes, György (2015) Effects of Aβ exposure on longterm associative memory and its neuronal mechanisms in a defined neuronal network. Scientific Reports, 5. p. 10614. ISSN 2045-2322

Kaltofen, Sabine, Li, Chenge, Huang, Po-Ssu, Serpell, Louise C, Barth, Andreas and André, Ingemar (2015) Computational de novo design of a self-assembling peptide with predefined structure. Journal of Molecular Biology, 427 (2). pp. 550-562. ISSN 0022-2836

Ratnayaka, J A, Serpell, L C and Lotery, A J (2015) Dementia of the eye: the role of amyloid beta in retinal degeneration. Eye, 29. pp. 1013-1026. ISSN 0950-222X

Morris, Kyle L, Chen, Lin, Rodger, Alison, Adams, Dave J and Serpell, Louise C (2015) Structural determinants in a library of low molecular weight gelators. Soft Matter, 11 (6). pp. 1174-1181. ISSN 1744-683X

Langkilde, A E, Morris, K L, Serpell, L C, Svergun, D I and Vestergaard, B (2015) The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy. Acta Crystallographica Section D: Biological Crystallography, 71 (4). pp. 882-895. ISSN 1399-0047

Colquhoun, Catherine, Draper, Emily R, Eden, Edward G B, Cattoz, Beatrice N, Morris, Kyle, Chen, Lin, McDonald, Tom O, Terry, Ann E, Griffiths, Peter C, Serpell, Louise C and Adams, Dave J (2014) The effect of self-sorting and co-assembly on the mechanical properties of low molecular weight hydrogels. Nanoscale, 22 (6). pp. 13719-13725. ISSN 2040-3364

Sanders, David W, Kaufman, Sarah K, DeVos, Sarah L, Sharma, Apurwa M, Mirbaha, Hilda, Li, Aimin, Barker, Scarlett J, Foley, Alex C, Thorpe, Julian R, Serpell, Louise C, Miller, Timothy M, Grinberg, Lea T, Seeley, William W and Diamond, Marc I (2014) Distinct tau prion strains propagate in cells and mice and define different tauopathies. Neuron, 82 (6). pp. 1271-1288. ISSN 0896-6273

Mangione, P Patrizia, Porcari, Riccardo, Gillmore, Julian D, Pucci, Piero, Monti, Maria, Porcari, Mattia, Giorgetti, Sofia, Marchese, Loredana, Raimondi, Sara, Serpell, Louise C, Chen, Wenjie, Relini, Annalisa, Marcoux, Julien, Clatworthy, Innes R, Taylor, Graham W, Tennent, Glenys A, Robinson, Carol V, Hawkins, Phillip N, Stoppini, Monica, Wood, Stephen P, Pepys, Mark B and Bellotti, Vittorio (2014) Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proceedings of the National Academy of Sciences, 111 (4). pp. 1539-1544. ISSN 0027-8424

Marshall, Karen E, Marchante, Ricardo, Xue, Wei-Feng and Serpell, Louise C (2014) The relationship between amyloid structure and cytotoxicity. Prion, 8 (2). pp. 5-4. ISSN 1933-6896

Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William, Morris, Kyle L, Sada, Alaa, Thorpe, Julian R and Serpell, Louise C (2013) A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease. Acta Neuropathologica Communications, 1 (83). pp. 1-17. ISSN 2051-5960

Morris, Kyle L, Zibaee, Shahin, Chen, Lin, Goedert, Michel, Sikorski, Pawel and Serpell, Louise C (2013) The structure of cross-β tapes and tubes formed by an octapeptide, αSβ1. Angewandte Chemie International Edition, 52 (8). pp. 2279-2283. ISSN 1433-7851

Morris, Kyle L, Chen, Lin, Raeburn, Jaclyn, Sellick, Owen R, Cotanda, Pepa, Paul, Alison, Griffiths, Peter C, King, Stephen M, O’Reilly, Rachel K, Serpell, Louise C and Adams, Dave J (2013) Chemically programmed self-sorting of gelator networks. Nature Communications, 4. p. 1480. ISSN 2041-1723

Morris, Kyle L, Rodger, Alison, Hicks, Matthew R, Debulpaep, Maya, Schymkowitz, Joost, Rousseau, Frederic and Serpell, Louise C (2012) Exploring the sequence-structure relationship for amyloid peptides. Biochemical Journal, 450. pp. 275-283. ISSN 0264-6021

Soura, Violetta, Stewart-Parker, Maris, Williams, Thomas L, Ratnayaka, Arjuna, Atherton, Joe, Gorringe, Kirsti, Tuffin, Jack, Darwent, Elisabeth, Rambaran, Roma, Klein, William, Lacor, Pascale, Staras, Kevin, Thorpe, Julian and Serpell, Louise (2012) Visualisation of co-localisation in Ab42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death. Biochemical Journal, 441 (2). pp. 579-590. ISSN 0264-6021

Soura, Violetta, Stewart‑Parker, Maris, Williams, Thomas L, Ratnayaka, Arjuna, Atherton, Joe, Gorringe, Kirsti, Tuffin, Jack, Darwent, Elisabeth, Rambaran, Roma, Klein, William, Lacor, Pascale, Staras, Kevin and Serpell, Louise C (2012) Visualization of co-localization in Aβ42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death. Biochemical Journal, 441 (2). pp. 579-590. ISSN 0264-6021

Williams, Thomas L, Johnson, Benjamin R G, Urbanc, Brigita, Jenkins, A Toby A, Connell, Simon D A and Serpell, Louise C (2011) Alzheimer's Aß42 oligomers but not fibrils simultaneously bind to and cause damage to ganglioside containing lipid membranes. Biochemical Journal, 439. pp. 67-77.

Marshall, Karen, Morris, Kyle L, Charlton, Deborah, O’Reilly, Nicola, Lewis, Laurence, Walden, Helen and Serpell, Louise C (2011) Hydrophobic, aromatic and electrostatic interactions play a central role in amyloid fibril formation. Biochemistry, 50 (12). pp. 2061-2071. ISSN 0006-2960

Serpell, Louise, Adams, Dave, Chen, Lin, Lotze, Gudrun, Morris, Kyle, Pont, Guillaume and Squires, Adam (2011) Salt-induced hydrogelation of functionalised-dipeptides at high pH. Chemical Communications, 47. 12071 - 12073. ISSN 1359-7345

Serpell, Louise, Crowther, Damian, Hider, Robert, Liu, Beinan, Lomas, David, Marciniak, Stefan, Meehan, Sarah, Moloney, Aileen, Morris, Kyle and Thomas, Sally (2010) Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation. Journal of Biological Chemistry, 286. pp. 4248-4256. ISSN 0021-9258

Williams, Thomas L, Day, Iain J and Serpell, Louise C (2010) The Effect of Alzheimer’s Aβ Aggregation State on the Permeation of Biomimetic Lipid Vesicles. Langmuir, 26 (22). pp. 17260-17268. ISSN 0743-7463

Chen, Lin, Revel, Steven, Morris, Kyle, Spiller, David G, Serpell, Louise C and Adams, Dave J (2010) Low molecular weight gelator-dextran composites. Chemical Communications, 46 (36). pp. 6738-40. ISSN 1364-548X

Morris, Kyle and Serpell, Louise (2010) From natural to designer self-assembling biopolymers, the structural characterisation of fibrous proteins & peptides using fibre diffraction. Chemical Society Reviews, 39 (9). pp. 3445-53. ISSN 1460-4744

Andersen, Christian Beyschau, Hicks, Matthew R., Vetri, Valeria, Vandahl, Brian, Rahbek-Nielsen, Henrik, Thøgersen, Henning, Thøgersen, Ida Bukh, Enghild, Jan Johannes, Serpell, Louise C, Rischel, Christian and Otzen, Daniel Erik (2010) Glucagon Fibril Polymorphism Reflects Differences in Protofilament Backbone Structure. Journal of Molecular Biology, 397 (4). pp. 932-946. ISSN 0022-2836

Chen, Lin, Morris, Kyle, Laybourn, Andrea, Elias, David, Hicks, Matthew R, Rodger, Alison, Serpell, Louise and Adams, Dave J (2010) Self-assembly mechanism for a naphthalene-dipeptide leading to hydrogelation. Langmuir, 26 (7). pp. 5232-5242. ISSN 0743-7463

Maurer-Stroh, Sebastian, Debulpaep, Maja, Kuemmerer, Nico, de la Paz, Manuela Lopez, Martins, Ivo Cristiano, Reumers, Joke, Morris, Kyle L, Copland, Alastair, Serpell, Louise, Serrano, Luis, Schymkowitz, Joost W H and Rousseau, Frederic (2010) Exploring the sequence determinants of amyloid structure using position-specific scoring matrices. Nature Methods, 7 (3). 237-U109. ISSN 1548-7091

Jahn, Thomas R, Makin, O Sumner, Morris, Kyle L, Marshall, Karen E, Tian, Pei, Sikorski, Pawel and Serpell, Louise C (2010) The Common Architecture of Cross-beta Amyloid. Journal of Molecular Biology, 395 (4). pp. 717-727. ISSN 0022-2836

Marshall, Karen E, Hicks, Matthew R, Williams, Thomas L, Hoffmann, Søren Vrønning, Rodger, Alison, Dafforn, Timothy R and Serpell, Louise (2010) Characterizing the Assembly of the Sup35 Yeast Prion Fragment, GNNQQNY: Structural Changes Accompany a Fiber-to-Crystal Switch. Biophysical Journal, 98 (2). pp. 330-338. ISSN 0006-3495

Marshall, Karen E and Serpell, Louise C (2010) Fibres, crystals and polymorphism: the structural promiscuity of amyloidogenic peptides. Soft Matter, 6. 2110 - 2114.

Serpell, Louise, Day, Iain and Williams, Thomas (2010) The effect of Alzheimer's Aß aggregation state on the permeation of biomimetic lipid vesicles. Langmuir, 26 (22). pp. 17260-17268. ISSN 0743-7463

Glockling, S L and Serpell, L C (2010) A new species of aplanosporic Haptoglossa, H. beakesii, with vesiculate spore release. Botany, 88 (1). pp. 93-101. ISSN 1916-2790

Maurstad, Gjertrud, Prass, Marcus, Serpell, Louise C and Sikorski, Pawel (2009) Dehydration stability of amyloid fibrils studied by AFM. European Biophysics Journal, 38 (8). pp. 1135-1140. ISSN 0175-7571

Tamamis, Phanourios, Adler-Abramovich, Lihi, Reches, Meital, Marshall, Karen, Sikorski, Pawel, Serpell, Louise, Gazit, Ehud and Archontis, Georgios (2009) Self-Assembly of Phenylalanine Oligopeptides: Insights from Experiments and Simulations. Biophysical Journal, 96 (12). pp. 5020-5029. ISSN 0006-3495

Hagenau, Anja, Scheidt, Holger A, Serpell, Louise, Huster, Daniel and Scheibel, Thomas (2009) Structural Analysis of Proteinaceous Components in Byssal Threads of the Mussel Mytilus galloprovincialis. Macromolecular Bioscience, 9 (2). pp. 162-168. ISSN 1616-5187

Marshall, Karen E and Serpell, Louise C (2009) The structural integrity of β-sheet assembly. Biochemical Society Transactions, 37 (4). pp. 671-676. ISSN 0300-5127

Madine, Jillian, Copland, Alastair, Serpell, Louise C and Middleton, David A (2009) Cross-ß spine architecture of fibrils formed by the amyloidogenic segment NFGSVQFV of medin from solid-state NMR and X-ray fibre diffraction measurements. Biochemistry, 48 (14). pp. 3089-3099. ISSN 0006-2960

Banwell, Eleanor F, Abelardo, Edgardo S, Adams, Dave J, Birchall, Martin A, Corrigan, Adam, Donald, Athene M, Kirkland, Mark, Serpell, Louise C, Butler, Michael F and Woolfson, Derek N (2009) Rational design and application of alpha-helical peptide hydrogels. Nature Materials, 8 (7). pp. 596-600. ISSN 1476-1122

Marshall, Karen E and Serpell, Louise C (2009) Structural integrity of ß-sheet assembly. Biochemical Society Transactions, 37. pp. 671-676. ISSN 0300-5127

Madine, Jillian, Jack, Edward, Stockley, Peter G, Radford, Sheena E, Serpell, Louise C and Middleton, David A (2008) Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fibre diffraction. Journal of American Chemical Society, 130 (45). pp. 14990-15001. ISSN 0002-7863

Rambaran, Roma N and Serpell, Louise C (2008) Amyloid fibrils: abnormal protein assembly. Prion, 2 (3). pp. 112-117. ISSN 1933-690X

Steinmetz, Michel O, Gattin, Zrinka, Verel, Rene, Ciani, Barbara, Stromer, Thusnelda, Green, Janelle M, Tittmann, Peter, Schulze-Briese, Clemens, Gross, Heinz, van Gunsteren, Wilfred F, Meier, Beat H, Serpell, Louise C, Müller, Shirley A and Kammerer, Richard A (2008) Atomic models of de novo designed cc beta-met amyloid-like fibrils. Journal of Molecular Biology, 376 (3). pp. 898-912. ISSN 0022-2836

Fukuma, Takeshi, Mostaert, Anika S, Serpell, Louise C and Jarvis, Suzanne P (2008) Revealing molecular-level surface structure of amyloid fibrils in liquid by means of frequency modulation atomic force microscopy. Nanotechnology, 19 (38). pp. 384010-384016. ISSN 0957-4484

Zibaee, Shahin, Jakes, Ross, Fraser, Graham, Serpell, Louise C, Crowther, R Anthony and Goedert, Michel (2007) Sequence Determinants for Amyloid Fibrillogenesis of Human a-Synuclein. Journal of Molecular Biology, 374 (2). pp. 454-464. ISSN 0022-2836

Makin, O Sumner, Sikorski, Pawel and Serpell, Louise C (2007) CLEARER: a new tool for the analysis of X-ray fibre diffraction patterns and diffraction simulation from atomic structural models. Journal of Applied Crystallography, 40 (5). pp. 966-972. ISSN 0021-8898

Papapostolou, David, Smith, Andrew M, Atkins, Edward D T, Oliver, Seb J, Ryadnov, Maxim G, Serpell, Louise C and Woolfson, Derek N (2007) Engineering nanoscale order into a designed protein fiber. Proceedings of the National Academy of Sciences, 104 (26). pp. 10853-10858. ISSN 0027-8424

Zibaee, Shahin, Makin, O Sumner, Goedert, Michel and Serpell, Louise C (2007) A simple algorithm locates beta-strands in the amyloid fibril core of alpha-synuclein, Abeta, and tau using the amino acid sequence alone. Protein Science, 16 (5). pp. 906-918. ISSN 1469-896X

Slotta, Ute, Hess, Simone, Spieß, Kristina, Stromer, Thusnelda, Serpell, Louise and Scheibel, Thomas (2007) Spider Silk and Amyloid Fibrils: A Structural Comparison. Macromolecular Bioscience, 7 (2). pp. 183-188. ISSN 1616-5187

Serpell, Louise C, Benson, Merrill, Liepnieks, Juris J and Fraser, Paul E (2007) Structural analyses of fibrinogen amyloid fibrils. Amyloid, 14 (3). pp. 199-203. ISSN 1350-6129

Stanley, Peter, Serpell, Louise C and Stein, Penelope E (2006) Polymerization of human angiotensinogen: insights into its structural mechanism and functional significance. Biochemical Journal, 400 (1). pp. 169-178. ISSN 0264-6021

Ranson, Neil, Stromer, Thusnelda, Bousset, Luc, Melki, Ronald and Serpell, Louise C (2006) Insights into the architecture of the ure2p yeast protein assemblies from helical twisted fibrils. Protein Science, 15 (11). pp. 2481-2487. ISSN 0961-8368

Makin, O Sumner, Sikorski, Pawel and Serpell, Louise C (2006) Diffraction to study protein and peptide assemblies. Current Opinion in Chemical Biology, 10 (5). pp. 417-422. ISSN 1367-5931

Li, Wei, Serpell, Louise C, Carter, Wendy J, Rubinsztein, David C and Huntington, James A (2006) Expression and Characterization of Full-length Human Huntingtin, an Elongated HEAT Repeat Protein. Journal of Biological Chemistry, 281 (23). pp. 15916-15922. ISSN 0021-9258

Yoshida, Hirotaka, Craxton, Molly, Jakes, Ross, Zibaee, Shahin, Tavare, Richard, Fraser, Graham, Serpell, Louise, Davletov, Bazbek, Crowther, R. Anthony and Goedert, Michel (2006) Synuclein Proteins of the Pufferfish Fugu rubripes: Sequences and Functional Characterization. Biochemistry, 45 (8). pp. 2599-2607. ISSN 0006-2960

Makin, O Sumner and Serpell, Louise C (2005) Structures for amyloid fibrils (mini-review). FEBS Journal, 272 (23). pp. 5950-5961. ISSN 1742-464X

Stromer, Thusnelda and Serpell, Louise C (2005) Structure and morphology of the Alzheimer's amyloid fibril. Microscopy Research and Technique, 67 (3-4). pp. 210-217. ISSN 1059-910X

Makin, O Sumner, Atkins, Edward, Sikorski, Pawel, Johansson, Jan and Serpell, Louise C (2005) Molecular basis for amyloid fibril formation and stability. Proceedings of the National Academy of Sciences, 102 (2). pp. 315-320. ISSN 0027-8424

Makin, O Sumner and Serpell, Louise C (2004) X-Ray Diffraction Studies of Amyloid Structure. Methods in Molecular Biology, 299. pp. 67-80. ISSN 1064-3745

Choi, Woong, Zibaee, Shahin, Jakes, Ross, Serpell, Louise C, Davletov, Bazbek, Crowther, R Anthony and Goedert, Michel (2004) Mutation E46K increases phospholipid binding and assembly into filaments of human alpha-synuclein . FEBS Letters, 576 (3). pp. 363-368. ISSN 0014-5793

Dafforn, Timothy R, Rajendra, Jacindra, Halsall, David J, Serpell, Louise C and Rodger, Alison (2004) Protein Fiber Linear Dichroism for Structure Determination and Kinetics in a Low-Volume, Low-Wavelength Couette Flow Cell. Biophysical Journal, 86 (1). pp. 404-410. ISSN 0006-3495

Makin, O Sumner and Serpell, Louise C (2004) Structural characterisation of islet amyloid polypeptide fibrils. Journal of Molecular Biology, 335 (5). pp. 1279-1288. ISSN 0022-2836

Makin, O Sumner and Serpell, Louise C (2004) The Structure of Amyloid. Fibre Diffraction Review, 12. pp. 29-35. ISSN 1463-8401

Smith, David P, Jones, Susan, Serpell, Louise C, Sunde, Margaret and Radford, Sheena E (2003) A Systematic Investigation into the Effect of Protein Destabilisation on Beta 2-Microglobulin Amyloid Formation. Journal of Molecular Biology, 330 (5). pp. 943-954. ISSN 0022-2836

Crowther, Damian C, Serpell, Louise C, Daffron, Timothy R, Gooptu, Bibek and Lomas, David A (2003) Nucleation of alpha1-Antichymotrypsin Polymerization. Biochemistry, 42 (8). pp. 2355-2363. ISSN 0006-2960

Sikorski, Pawel, Atkins, Edward D T and Serpell, Louise C (2003) Structure and textures of fibrous crystals of the Abeta (11-25) peptide fragment from Alzheimer's Abeta Amyloid protein. Structure, 11 (1). pp. 1-2. ISSN 0969-2126

Berriman, John, Serpell, Louise C, Oberg, Keith A, Fink, Anthony L, Goedert, Michel and Crowther, R Anthony (2003) Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-ß structure. Proceedings of the National Academy of Sciences, 100 (15). pp. 9034-9038. ISSN 0027-8424

Mastrangelo, Peter, Serpell, Louise, Dafforn, Tim, Lesk, Arthur, Fraser, Paul and Westaway, David (2002) A cluster of familial Creutzfeldt-Jakob disease mutations recapitulate conserved residues in Doppel: a case of molecular mimicry? FEBS Letters, 532 (1-2). pp. 21-26. ISSN 0014-5793

David, Della C, Layfield, Robert, Serpell, Louise, Narain, Yolanda, Goeder, Michel and Spillantini, Maria Grazia (2002) Proteasomal degradation of tau protein. Journal of Neurochemistry, 83 (1). pp. 176-185. ISSN 0022-3042

Derbyshire, Dean J, Basu, Balaku P, Serpell, Louise C, Joo, Woo S, Date, Takayasu, Iwabuchi, Kuniyoshi and Doherty, Aidan J (2002) Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor. EMBO Journal, 21 (14). pp. 3863-3872. ISSN 0261-4189

Makin, O S and Serpell, L C (2002) Examining the structure of the mature amyloid fibril. Biochemical Society Transactions, 30 (4). pp. 521-525. ISSN 0300-5127

Yang, D S, Serpell, L C, Yip, C M, McLaurin, J, Chrishti, M A, Horne, P, Boudreau, L, Kisilevsky, R, Westaway, D and Fraser, P E (2001) Assembly of Alzheimer's amyloid-beta fibrils and approaches for therapeutic intervention. Amyloid, 8 (9). ISSN 1350-6129

Jaikaran, Emma T A S, Higham, Claire E, Serpell, Louise C, Zurdo, Jesús, Gross, Michael, Clark, Anne and Fraser, Paul E (2001) Identification of a novel human islet amyloid polypeptide b-sheet domain and factors influencing fibrillogenesis. Journal of Molecular Biology, 308 (3). pp. 515-525. ISSN 0022-2836

Goedert, Michel, Spillantini, Maria Grazia, Serpell, Louise C, Berriman, John, Smith, Michael J, Jakes, Ross and Crowther, R Anthony (2001) From genetics to pathology: tau and a-synuclein assemblies in neurodegenerative diseases. Philosophical Transactions B: Biological Sciences, 356 (1406). pp. 213-227. ISSN 1471-2970

Serio, Tricia R, Cashikar, Anil G, Kowal, Anthony S, Sawicki, George J, Moslehi, Jahan J, Serpell, Louise, Arnsdorf, Morton F and Lindquist, Susan L (2000) Nucleated conformational conversion and the replication of conformational information by a prion determinant. Science, 289 (5483). pp. 1317-1321. ISSN 00368075

Serpell, Louise (2000) Alzheimer's amyloid fibrils: structure and assembly. BBA - Molecular Basis of Disease, 1502 (1). pp. 16-30. ISSN 0925-4439

Fraser, Paul E, Yang, Dun-Sheng, Yu, Gang, Lévesque, Lyne, Nishimura, Masaki, Arawaka, Shigeki, Serpell, Louise, Rogaeva, Ekaterina and St George-Hyslop, Peter (2000) Presenilin structure, function and role in Alzheimer disease. BBA - Molecular Basis of Disease, 1502 (1). ISSN 0925-4439

Serpell, Louise C, Sunde, Margaret, Benson, Merrill D, Tennent, Glenys A, Pepys, Mark B and Fraser, Paul E (2000) The protofilament substructure of amyloid fibrils. Journal of Molecular Biology, 330 (5). pp. 1033-1039. ISSN 00222836

Lashuel, Hilal A, LaBrenz, Steven R, Woo, Linda, Serpell, Louise C and Kelly, Jeffery W (2000) Protofilaments, filaments, ribbons, and fibrils from peptidomimetic self-assembly: Implications for amyloid fibril formation and materials science. Journal of the American Chemical Society, 122 (22). pp. 5262-5277. ISSN 00027863

Serpell, Louise C and Smith, Judith M (2000) Direct visualisation of the ß-sheet structure of synthetic Alzheimer's amyloid. Journal of Molecular Biology, 299 (1). pp. 225-231. ISSN 00222836

Serpell, Louise C, Barriman, John, Jakes, Ross, Goedert, Michel and Crowther, R Anthony (2000) Fiber diffraction of synthetic a-synuclein filaments shows amyloid-like cross-ß conformation. Proceedings of the National Academy of Sciences, 97 (9). ISSN 0027-8424

Serpell, Louise (1999) X-ray fiber diffraction of amyloid fibrils. Methods in Enzymology, 309. pp. 526-536. ISSN 00766879

Serpell, L, Blake, C and Sunde, M (1997) The molecular basis of amyloidosis. Cellular and Molecular Life Sciences, 53 (11-12). pp. 871-887. ISSN 1420-682X

Sunde, Margaret, Serpell, Louise C, Bartlam, Mark, Fraser, Paul E, Pepys, Mark B and Blake, Colin C F (1997) Common core structure of amyloid fibrils by synchrotron X-ray diffraction. Journal of Molecular Biology, 273 (3). pp. 729-739. ISSN 00222836

Blake, Colin and Serpell, Louise (1996) Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous ß-sheet helix. Structure, 4 (8). pp. 989-998. ISSN 09692126

Pepys, M B, Serpell, Louise and et al, (1996) Molecular mechanisms of fibrillogenesis and the protective role of amyloid P component: Two possible avenues for therapy. CIBA Foundation Symposia, 199. pp. 73-89. ISSN 0300-5208

Serpell, Louise C, Goldsteins, Gundars, Dacklin, Ingrid, Lundgren, Erik and Blake, Colin C F (1996) The "edge strand" hypothesis: Prediction and test of a mutational "hot-spot" on the transthyretin molecule associated with FAP amyloidogenesis. Amyloid, 3 (2). pp. 75-85. ISSN 1350-6129

Doherty, Aidan J, Serpell, Louise C and Ponting, Christopher P (1996) The helix-hairpin-helix DNA-binding motif: A structural basis for non-sequence-specific recognition of DNA. Nucleic Acids Research, 24 (13). pp. 2488-2497. ISSN 03051048

Blake, Colin C F, Serpell, Louise C, Sunde, Margaret, Sandgren, Ola and Lundgren, Erik (1996) A molecular model of the amyloid fibril. CIBA Foundation Symposia, 199. pp. 6-21. ISSN 0300-5208

Serpell, L C, Sunde, M, Fraser, P E, Luther, P K, Morris, E P, Sangren, O, Lundgren, E and Blake, C C F (1995) Examination of the structure of the transthyretin amyloid fibril by image reconstruction from electron micrographs. Journal of Molecular Biology, 254 (2). pp. 113-118. ISSN 00222836

Book Section

Vadukul, Devekee M, Al-Hilaly, Youssra K and Serpell, Louise C (2018) Methods for structural analysis of amyloid fibrils in misfolding diseases. In: Gomes, Cláudio M (ed.) Protein misfolding diseases. Humana Press, New York, NY, pp. 109-122. ISBN 9781493988198

Scheibel, Thomas and Serpell, Louise (2005) Physical Methods for Studies of Fiber Formation and Structure. In: Protein folding handbook. Wiley-VCH, pp. 197-253. ISBN 9783527307845


University of Sussex (2016) Alzheimer's disease. .

This list was generated on Sun Jun 26 09:57:36 2022 BST.