Article

West, Ryan A, O'Doherty, Oran G, Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E, Rao, Srinivasa P S, Williams, Gareth and Ward, Simon E (2017) African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase. European Journal of Medicinal Chemistry, 141. pp. 676-689. ISSN 0223-5234

Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W and Oliver, Antony W (2016) Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal, 473 (13). pp. 1869-1879. ISSN 0264-6021

Burrows, Andrew D, Jurcic, Monika, Keenan, Luke L, Lane, Rebecca A, Mahon, Mary F, Warren, Mark R, Nowell, Harriot, Paradowski, Michael and Spencer, John (2013) Incorporation by coordination and release of the iron chelator drug deferiprone from zinc-based metal–organic frameworks. Chemical Communications, 49. pp. 11260-11262. ISSN 1359-7345

Paradowski, Michael (2011) A flexible synthesis of C-6 and N-1 analogues of a 4-amino-1,3-dihydroimidazo[4,5-c]pyridin-2-one core. Tetrahedron Letters, 52 (44). pp. 5728-5732. ISSN 00404039

Paradowski, Michael (2011) Challenges of drug discovery in novel target space. The Discovery and Evaluation of PF-3893787: A Novel Histamine H4 Receptor Antagonist. Bioorganic and Medicinal Chemistry Letters, 21. pp. 6596-6602. ISSN 0960894X

Egan, Ben A, Paradowski, Michael, Thomas, Lynne H and Marquez, Rodolfo (2011) Synthesis of the C1-C16 fragment of the ajudazols. Tetrahedron, 67 (50). pp. 9700-9707. ISSN 0040-4020

Paradowski, Michael (2011) Development of a Practical Synthesis of Toll-like Receptor Agonist PF-4171455: 4-Amino-1-benzyl-6-trifluoromethyl-1,3-dihydroimidazo [4,5-c] pyridin-2-one. Organic Process Research and Development, 45 (4). pp. 788-796. ISSN 10836160

Paradowski, Michael (2011) Regiocontrolled Rearrangement of Isobenzofurans. Organic Letters, 13 (8). pp. 2086-2089. ISSN 15237060

Paradowski, Michael (2011) Synthesis of a novel octahydro pyrrolo[3,4-c] pyrrole cyclic amidine via 1,3-dipolar cycloaddition of azomethine ylides. Synlett (11). pp. 1543-1546. ISSN 09365214

Paradowski, Michael (2011) The discovery of a novel prototype small molecule TLR7 agonist for the treatment of hepatitis C virus infection. MedChemComm, 2 (3). pp. 185-189. ISSN 20402503

Conference or Workshop Item

Paradowski, Michael (2010) Novel isobenzofuran oxidative rearrangements: Total synthesis of Ajudazol A. In: 239th ACS National Meeting, San Francisco, CA, United States.

Thesis

Paradowski, Michael (2017) Spirooxindoles derivatives as novel inhibitors of the respiratory syncytial virus. Doctoral thesis (PhD), University of Sussex.