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Hassell-Hart, Storm, Picaud, Sarah, Lengacher, Raphael, Csucker, Joshua, Millet, Regis, Gasser, Gilles, Alberto, Roger, Maple, Hannah, Felix, Robert, Leśnikowski, Zbigniew J, Stewart, Helen J S, Chevassut, Timothy J, Morley, Simon, Filippakopoulos, Panagis and Spencer, John (2021) Probing BRD inhibition substituent effects in bulky analogues of (+)-JQ1. Helvetica Chimica Acta, 104 (3). a2000214 1-7. ISSN 0018-019X
Latif, Anne-Louise, Newcombe, Ashley, Li, Sha, Gilroy, Kathryn, Robertson, Neil A, Lei, Xue, Stewart, Helen J S, Cole, John, Terradas, Maria Terradas, Rishi, Loveena, McGarry, Lynn, McKeeve, Claire, Reid, Claire, Clark, William, Chevassut, Timothy J T and others, (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12 (1). a241 1-16. ISSN 2041-1723
Hassell-Hart, Storm, Runcie, Andrew, Krojer, Tobias, Doyle, Jordan, Lineham, Ella, Ocasio, Cory A, Neto, Brenno A D, Fedorov, Oleg, Marsh, Graham, Maple, Hannah, Felix, Robert, Banks, Rebecca, Ciulli, Alessio, Picaud, Sarah, Filippakopoulos, Panagis, von Delft, Frank, Brennan, Paul, Stewart, Helen J S, Chevassut, Timothy J, Walker, Martin, Austin, Carol, Morley, Simon and Spencer, John (2019) Synthesis and biological investigation of (+)-JD1, an organometallic BET bromodomain inhibitor. Organometallics. ISSN 0276-7333
Robinson, Sophie R, Viegas, Sandra C, Matos, Rute G, Domingues, Susana, Bedir, Marisa, Stewart, Helen J S, Chevassut, Timothy, Oliver, Antony W, Arraiano, Cecilia M and Newbury, Sarah F (2018) DIS3 isoforms vary in their endoribonuclease activity and are differentially expressed within haematological cancers. Biochemical Journal, 475 (12). pp. 2091-2105. ISSN 0264-6021
Stewart, Helen, Chaudry, Sabah, Crichlow, Asante, Feilding, Freya Luling and Chevassut, Timothy (2018) BET inhibition suppresses S100A8 and S100A9 expression in acute myeloid leukemia cells and synergises with daunorubicin in causing cell death. Bone Marrow Research, 2018 (574295). ISSN 2090-2999
Horne, Gillian Abigail, Bastow, Sarah, Stewart, Helen Jayne Susan and Chevassut, Timothy James Telfer (2013) BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1. Cancer Medicine, 2 (6). pp. 826-835. ISSN 2045-7634
Rider, Tom, Powell, Robert, Gover, Rebecca, Ansell, Richard, Bastow, Sarah, Ghurye, Rohit R, Stewart, Helen and Chevassut, Timothy (2013) Molecular detection of BRAF-V600E is superior to flow cytometry for disease evaluation in hairy cell leukaemia. Hematological Oncology, 32 (3). pp. 158-161. ISSN 0278-0232
Brewin, John N, Horne, Gillian A, Bisling, Kathrin E, Stewart, Helen J and Chevassut, Timothy J (2013) Rapid detection of DNMT3A R882 codon mutations allows early identification of poor risk patients with acute myeloid leukemia. Leukemia & Lymphoma, 54 (6). pp. 1336-1339. ISSN 1042-8194
Jones, C I, Zabolotskaya, M V, King, A J, Stewart, H J S, Horne, G A, Chevassut, T J and Newbury, S F (2012) Identification of circulating microRNAs as diagnostic biomarkers for use in multiple myeloma. British Journal of Cancer, 107 (12). pp. 1987-1996. ISSN 0007-0920
The University of Sussex (2011) Novel biomarkers in plasma cell disorders. WO/2012/080721 A2.
Guildford, Anna L, Stewart, Helen J S, Morris, Christopher and Santin, Matteo (2011) Substrate-induced phenotypic switches of human smooth muscle cells: an in vitro study of in-stent restenosis activation pathways. Journal of the Royal Society Interface, 8 (58). pp. 641-9. ISSN 1742-5689
Stewart, Helen J.S., Kishikova, Lyudmila, Powell, Fiona L., Wheatley, Sally P. and Chevassut, Timothy J. (2011) The polo-like kinase inhibitor BI 2536 exhibits potent activity against malignant plasma cells and represents a novel therapy in multiple myeloma. Experimental Hematology, 39 (3). pp. 330-338. ISSN 0301-472X
Stewart, Helen, Kishikova, Lyudmila, Powell, Fiona, Wheatley, Sally Paula and Chevassut, Timothy (2011) The polo-like kinase inhibitor BI 2536 exhibits potent activity against malignant plasma cells and represents a novel therapy in multiple myeloma. Experimental Hematology, 39 (3). pp. 330-338. ISSN 0301-472X
Malik, Reshad K J, Ghurye, Rohit R, Lawrence-Watt, Diana J and Stewart, Helen J S (2009) Galectin-1 stimulates monocyte chemotaxis via the p44/42 MAP kinase pathway and a pertussis toxin-sensitive pathway. Glycobiology, 19 (12). pp. 1402-7. ISSN 1460-2423
Stewart, H J S, Guildford, A L, Lawrence-Watt, D J and Santin, M (2009) Substrate-induced phenotypical change of monocytes/macrophages into myofibroblast-like cells: a new insight into the mechanism of in-stent restenosis. Journal of Biomedical Materials Research Part A, 90 (2). pp. 465-71. ISSN 1549-3296