Items for Rulten, Stuart

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Article

Komulainen, Emilia, Badman, Jack, Rey, Stephanie, Rulten, Stuart, Ju, Limei, Fennell, Kate, Kalasova, Ilona, Ilievova, Kristyna, McKinnon, Peter J, Hanzlikova, Hana, Staras, Kevin and Caldecott, Keith W (2021) Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures. EMBO Reports, 22 (5). a51851 1-12. ISSN 1469-221X

Zeng, Zhihong, Rulten, Stuart L, Breslin, Claire, Zlatanou, Anastasia, Coulthard, Victoria and Caldecott, Keith (2017) Acylpeptide hydrolase is a component of the cellular response to DNA damage. DNA Repair, 58. pp. 52-61. ISSN 1568-7864

Hoch, Nicolas C, Hanzlikova, Hana, Rulten, Stuart L, Tétreault, Martine, Komulainen, Emilia, Ju, Limei, Hornyak, Peter, Zeng, Zhihong, Gittens, William, Rey, Stephanie A, Staras, Kevin, Mancini, Grazia M S, McKinnon, Peter J, Wang, Zhao-Qi, Wagner, Justin D, Care4Rare Canada Consortium, , Yoon, Grace and Caldecott, Keith W (2017) XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia. Nature, 541. pp. 87-91. ISSN 0028-0836

Grundy, Gabrielle J, Polo, Luis M, Zeng, Zhihong, Rulten, Stuart L, Hoch, Nicolas C, Pathompong, Paomephan, Xu, Yingqi, Sweet, Steve M, Thorne, Alan W, Oliver, Antony W, Matthews, Steve J, Pearl, Laurence H and Caldecott, Keith W (2016) PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2). Nature Communications, 7 (1). a12404 1-12. ISSN 2041-1723

Rulten, Stuart and Caldecott, Keith (2016) The PARP inhibitor AZD2461 provides insights into the role of PARP3 inhibition for both synthetic lethality and tolerability with chemotherapy in preclinical models. Cancer Research, 76 (20). ISSN 0008-5472

Grundy, Gabrielle J, Rulten, Stuart L, Arribas-Bosacoma, Raquel, Davidson, Kathryn, Kozik, Zuzanna, Oliver, Antony W, Pearl, Laurence H and Caldecott, Keith W (2016) The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins. Nature Communications, 7 (1). a11242. ISSN 2041-1723

Peña-Oliver, Yolanda, Carvalho, Fabiana M, Sanchez-Roige, Sandra, Quinlan, Erin B, Jia, Tianye, Walker-Tilley, Tom, Rulten, Stuart L, Pearl, Frances M G, Banaschewski, Tobias, Barker, Gareth J, Bokde, Arun L W, Büchel, Christian, Conrod, Patricia J, Flor, Herta, Gallinat, Jürgen, Garavan, Hugh, Heinz, Andreas, Gowland, Penny, Paillere Martinot, Marie-Laure, Paus, Tomáš, Rietschel, Marcella, Robbins, Trevor W, Smolka, Michael N, Schumann, Gunter, Stephens, David N and for the IMAGEN Consortium, (2016) Mouse and human genetic analyses associate kalirin with ventral striatal activation during impulsivity and with alcohol misuse. Frontiers in Genetics, 7. a52. ISSN 1664-8021

Cherry, Amy L, Nott, Timothy J, Kelly, Geoffrey, Rulten, Stuart L, Caldecott, Keith W and Smerdon, Stephen J (2015) Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains. DNA repair, 35. pp. 116-125. ISSN 1568-7856

Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L, Hanzlikova, Hana, Oliver, Antony W and Caldecott, Keith W (2015) The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function. Nucleic Acids Research, 43 (14). pp. 6934-6944. ISSN 0305-1048

Dai, Xiaoxia, Rulten, Stuart L, You, Changjun, Caldecott, Keith W and Wang, Yinsheng (2015) Identification and functional characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in human Poly(ADP-ribose) Polymerase 3. Journal of proteome research, 14 (6). pp. 2575-2582. ISSN 1535-3907

Gomez Herreros, Fernando, Schuurs-Hoeijmakers, Janneke H M, McCormack, Mark, Greally, Marie T, Rulten, Stuart, Romero-Granados, Rocio, Counihan, Timothy J, Chaila, Elijah, Conroy, Judith, Ennis, Sean, Delanty, Norman, Cortes-Ledesma, Felipe, de Brouwer, Arjan P M, Cavalleri, Gianpiero L, El-Khamisy, Sherif F, de Vries, Bert B A and Caldecott, Keith W (2014) TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. Nature Genetics, 46 (5). pp. 516-521. ISSN 1061-4036

Grundy, Gabrielle J, Moulding, Hayley A, Caldecott, Keith W and Rulten, Stuart L (2014) One ring to bring them all--the role of Ku in mammalian non-homologous end joining. DNA repair, 17. pp. 30-38. ISSN 1568-7856

Rulten, Stuart L, Rotheray, Amy, Green, Ryan L, Grundy, Gabrielle J, Moore, Duncan A Q, Gómez-Herreros, Fernando, Hafezparast, Majid and Caldecott, Keith W (2014) PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage. Nucleic Acids Research, 42 (1). pp. 307-314. ISSN 1362-4962

Rulten, Stuart L and Caldecott, Keith W (2013) DNA strand break repair and neurodegeneration. DNA repair, 12 (8). pp. 558-567. ISSN 1568-7856

Grundy, Gabrielle L, Rulten, Stuart L, Zeng, Zhihong, Arribas-Bosacoma, Raquel, Iles, Natasha, Manley, Katie, Oliver, Antony and Caldecott, Keith W (2013) APLF promotes the assembly and activity of non-homologous end joining protein complexes. The EMBO journal, 32 (1). pp. 112-125. ISSN 1460-2075

Rulten, Stuart L, Fisher, Anna E O, Robert, Isabelle, Zuma, Maria C, Rouleau, Michele, Ju, Limei, Poirier, Guy, Reina-San-Martin, Bernardo and Caldecott, Keith W (2011) PARP-3 and APLF function together to accelerate nonhomologous end joining. Molecular Cell, 41 (1). pp. 33-45. ISSN 1097-2765

Rulten, Stuart L, Cortes-Ledesma, Felipe, Guo, Liandi, Iles, Natasha J and Caldecott, Keith W (2008) APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells. Molecular and Cellular Biology, 28 (14). pp. 4620-4628. ISSN 0270-7306

Rulten, S L, Hodder, E, Ripley, Tamzin, Stephens, D N and Mayne, L V (2008) Alcohol induces DNA damage and the Fanconi anemia D2 protein implicating FANCD2 in the DNA damage response pathways in brain. Alcoholism: Clinical and Experimental Research, 32 (7). pp. 1186-1196. ISSN 0145-6008

Iles, Natasha, Rulten, Stuart, El-Khamisy, Sherif F and Caldecott, Keith W (2007) APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks. Molecular and Cellular Biology, 27 (10). pp. 3793-3803. ISSN 0270-7306

Rulten, Stuart L, Ripley, Tamzin, Manerakis, Ektor, Stephens, David N and Mayne, Lynne V (2006) Ethanol modifies the effect of handling stress on gene expression: problems in the analysis of two-way gene expression studies in mouse brain. Brain Research, 1102 (-). ISSN 0006-8993

Rulten, Stuart L, Kinloch, Ross A, Tateossian, Hilda, Robinson, Colin, Gettins, Lucy and Kay, John E (2006) The human FK506-binding proteins: characterization of human FKBP19. Mammalian Genome, 17 (4). pp. 322-331. ISSN 0938-8990

Mead, A N, Morris, H V, Dixon, C I, Rulten, S L, Mayne, L V, Zamanillo, D and Stephens, D N (2006) AMPA receptor GluR2, but not GluR1 subunit deletion impairs emotional response conditioning in mice. Behavioral Neuroscience, 120 (2). pp. 241-8. ISSN 0735-7044

Rulten, S L, Ripley, Tamzin, Hunt, C L, Stephens, D N and Mayne, L V (2006) Sp1 and NFkappaB pathways are regulated in brain in response to acute and chronic ethanol. Genes, Brain and Behavior, 5 (3). pp. 257-273. ISSN 1601-1848

Rulten, Stuart, Thorpe, Julian, Mosaheb, Sabrina, Kay, John and Cairns, N (2004) Redistribution and Apparent Shortfalls of the Peptidyl-Prolyl cis-trans Isomerase Protein Pin1 within Subcellular Compartments of Neurons in a Range of Frontotemporal Dementias. Neurobiology of Disease.

Thorpe, Julian, Mosaheb, S, Hashemzadeh-Bonehi, L, Cairns, NJ, Kay, John Edward, Morley, Simon and Rulten, Stuart (2004) Shortfalls in the peptidyl-prolyl cis-trans isomerase protein Pin1 in neurons are associated with frontotemporal dementias. Neurobiology of Disease, 17 (2). pp. 237-249. ISSN 0969-9961

Pemberton, Trevor J, Rulten, Stuart L and Kay, John E (2003) Identification and characterisation of Schizosaccharomyces pombe cyclophilin 3 and its human homologue cyclophilin 20. Journal of Chromatography B, 786 (1-2). pp. 81-91. ISSN 1570-0232

Rulten, Stuart, Ripley, Tamzin and Mayne, Lynne (2002) Uniform Microarray Hybridisation: A Comparative Study. International Biotechnology Laboratory.

Thorpe, Julian R, Morley, Simon J and Rulten, Stuart L (2001) Utilizing the Peptidyl-Prolyl Cis-Trans Isomerase Pin 1 as a Probe of its Phosphorylated Target Proteins: Examples of Binding to Nuclear Proteins in a Human Kidney Cell Line and to Tau in Alzheimer's Diseased Brain. Journal of Histochemistry and Cytochemistry, 49 (1). pp. 97-108. ISSN 0022-1554

Thorpe, Julian R, Rulten, Stuart L and Kay, John E (1999) The binding of a putative and a known chaperone protein revealed by immunogold labelling transmission electron microscopy: A suggested use of chaperones as probes for the distribution of their target proteins. Journal of Histochemistry and Cytochemistry, 47. pp. 1633-1640.

Rulten, Stuart L, Thorpe, Julian R and Kay, John Edward (1999) Identification of eukaryotic parvulin homologues: a new subfamily of peptidylprolyl cis-trans isomerases. Biochemical and Biophysical Research Communications, 259 (3). pp. 557-562. ISSN 0006-291X

Book Section

Rulten, Stuart L, Dantzer, Francoise and Caldecott, Keith W (2015) The role of PARPs in DNA strand break repair. In: Curtin, Nicola J and Sharma, Ricky A (eds.) PARP Inhibitors for Cancer Therapy. Cancer Drug Discovery and Development, 83 . Humana Press, New York, pp. 47-78. ISBN 9783319141503

This list was generated on Wed Oct 4 23:38:50 2023 BST.