Article

Legan, Kevin, Goodyear, Richard, Morin, Matias, Mencia, Angeles, Pollard, Hilary, Olavarrieta, Leticia, Korchagina, Julia Jurievna, Modiamo-Hoybjor, Silvia, Mayo, Fernando, Moreno, Felipe, Moreno-Pelayo, Miguel-Angel and Richardson, Guy (2014) Three deaf mice: mouse models for TECTA-based human hereditary deafness reveal domain-specific structural phenotypes in the tectorial membrane. Human Molecular Genetics, 23 (10). pp. 2551-2568. ISSN 0964-6906

Lukashkin, Andrei N, Legan, P Kevin, Weddell, Thomas D, Lukashkina, Victoria A, Goodyear, Richard J, Welstead, Lindsey J, Petit, Christine, Russell, Ian J and Richardson, Guy P (2012) A mouse model for human deafness DFNB22 reveals that hearing impairment is due to a loss of inner hair cell stimulation. Proceedings of the National Academy of Sciences of the United States of America, 109 (47). pp. 19351-19356. ISSN 1091-6490

Zheng, Jing, Miller, Katharine K., Yang, Tao, Hildebrand, Michael S., Shearer, A. Eliot, DeLuca, Adam P., Scheetz, Todd E., Drummond, Jennifer, Scherer, Steve E., Legan, P Kevin, Goodyear, Richard J, Richardson, Guy P, Cheatham, Mary Ann, Smith, Richard J. and Dallos, Peter (2011) Carcinoembryonic antigen-related cell adhesion molecule 16 interacts with alpha-tectorin and is mutated in autosomal dominant hearing loss (DFNA4). Proceedings of the National Academy of Sciences, 108 (10). pp. 4218-4223.

Nayak, Gowri, Goodyear, Richard J, Legan, P Kevin, Noda, Masaharu and Richardson, Guy P (2011) Evidence for multiple, developmentally regulated isoforms of Ptprq on hair cells of the inner ear. Developmental Neurobiology, 71 (2). pp. 129-141.

Goodyear, Richard J, Legan, P Kevin, Christiansen, Jeffrey R, Xia, Bei, Korchagina, Julia, Gale, Jonathan E, Warchol, Mark E, Corwin, Jeffrey T and Richardson, Guy P (2010) Identification of the Hair Cell Soma-1 Antigen, HCS-1, as Otoferlin. Journal of the Association for Research in Otolaryngology, 11 (4). pp. 573-586. ISSN 1525-3961

Goodyear, Richard J, Forge, Andy, Legan, P Kevin and Richardson, Guy P (2010) Asymmetric Distribution of Cadherin 23 and Protocadherin 15 in the Kinocilial Links of Avian Sensory Hair Cells. Journal of Comparative Neurology, 518 (21). pp. 4288-4297. ISSN 0021-9967

Moreno-Pelayo, Miguel Ángel, Goodyear, Richard J, Mencía, Ángeles, Modamio-Høybjør, Silvia, Legan, P Kevin, Olavarrieta, Leticia, Moreno, Felipe and Richardson, Guy P (2008) Characterization of a spontaneous, recessive, missense mutation arising in the Tecta gene. Journal of the Association for Research in Otolaryngology, 9 (2). pp. 202-214. ISSN 1525-3961

Russell, Ian J, Legan, P Kevin, Lukashkina, Victoria A, Lukashkin, Andrei N, Goodyear, Richard J and Richardson, Guy P (2007) Sharpened cochlear tuning in a mouse with a genetically modified tectorial membrane. Nature Neuroscience, 10 (2). pp. 215-223. ISSN 1097-6256

McGee, JoAnn, Goodyear, Richard J, McMillan, D Randy, Stauffer, Eric A, Holt, Jeffrey R, Locke, Kirsten G, Birch, David G, Legan, P Kevin, White, Perrin C, Walsh, Edward J and Richardson, Guy P (2006) The very large G-protein coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles. Journal of Neuroscience, 26 (24). pp. 6543-6553. ISSN 0270-6474

Ahmed, Zubair M, Goodyear, Richard, Riazuddin, Saima, Lagziel, Ayala, Legan, P Kevin, Behra, Martine, Burgess, Shawn M, Lilley, Kathryn S, Wilcox, Edward R, Riazuddin, Sheikh, Griffith, Andrew J, Frolenkov, Gregory I, Belyantseva, Inna A, Richardson, Guy P and Friedman, Thomas B (2006) The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15. Journal of Neuroscience, 26 (26). pp. 7022-7034. ISSN 0270-6474

Legan, P Kevin, Lukashkina, Victoria A, Goodyear, Richard J, Lukashkin, Andrei N, Verhoeven, Kristien, Van Camp, Guy, Russell, Ian J and Richardson, Guy P (2005) A deafness mutation isolates a second role for the tectorial membrane in hearing. Nature Neuroscience, 8. pp. 1035-1042. ISSN 1097-6256

Lukashkin, A N, Lukashkina, V A, Legan, P K, Richardson, G P and Russell, I J (2004) Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic Tecta(deltaENT/deltaENT) mice. Journal of Neurophysiology, 91 (1). pp. 163-71. ISSN 0022-3077

Richardson, G P, Goodyear, R J, Legan, P K, Marcotti, W, Wright, M B, Oganesian, A, Booth, C J, Coates, S A, Kros, C J, Seifert, R A and Bowen-Pope, D F (2003) A receptor-like inositol lipid phosphatase required for the normal maturation of developing cochlear hair bundles. Journal of Neuroscience, 23 (27). pp. 9028-9219. ISSN 0270-6474

Goodyear, R J, Legan, P K, Wright, M B, Marcotti, W, Oganesian, A, Coats, S A, Booth, C J, Kros, C J, Seifert, R A, Bowen-Pope, D F and Richardson, G P (2003) A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles. Journal of Neuroscience, 23 (27). pp. 9208-9219. ISSN 0270-6474

Lukashkin, Andrei N, Lukashkina, Victoria A, Legan, P Kevin, Richardson, Guy P and Russell, Ian J (2003) Role of the tectorial membrane revealed by otoacoustic emissions recorded from wild-type and transgenic TectaENT/ENT mice. Journal of Neurophysiology, 91 (1). pp. 163-171. ISSN 0022-3077

Lukashkin, Andrei N, Lukashkina, Victoria A, Legan, P Kevin, Richardson, Guy P and Russell, Ian J (2003) Role of the Tectorial Membrane Revealed by Otoacoustic Emissions Recorded From Wild-Type and Transgenic Tecta¿ENT/¿ENT Mice. Journal of Neurophysiology, 91 (1). pp. 1163-1171. ISSN 0022-3077

Legan, P Kevin, Lukashkina, Victoria A, Kössl, Manfred, Goodyear, Richard J, Russell, Ian J and Richardson, Guy P (2000) A targeted deletion in alpha-tectorin reveals that the tectorial membrane is required for the gain and timing of cochlear feedback. Neuron, 28 (1). pp. 273-285. ISSN 08966273

Kruger, Robert P, Goodyear, Richard J, Legan, P Kevin, Warchol, Mark E, Raphael, Yehoash, Cotanche, Douglas A and Richardson, Guy P (1999) The supporting-cell antigen: a receptor-like protein tyrosine phosphatase expressed in the sensory epithelia of the inner ear. Journal of Neuroscience, 19 (12). pp. 4815-4827. ISSN 0270-6474

Coutinho, P, Goodyear, R, Legan, P K and Richardson, G P (1999) Chick a-tectorin: Molecular cloning and expression during embryogenesis. Hearing Research, 130 (1-2). pp. 62-74. ISSN 03785955

Rau, A, Legan, P K and Richardson, G P (1999) Tectorin mRNA is spatially and temporally restricted during mouse inner ear development. Journal of Comparative Neurology, 405 (2). pp. 271-280. ISSN 0021-9967

Van Laer, Lut, Huizing, Egbert H, Verstreken, Margriet, van Zuijlen, Diederick, Wauters, Jan G, Bossuyt, Paul J, Van de Heyning, Paul, McGuirt, Wyman T, Smith, Richard J H, Willems, Patrick J, Legan, P Kevin, Richardson, Guy P and Van Camp, Guy (1998) Nonsyndromic hearing impairment is associated with a mutation in DFNA5. Nature Genetics, 20 (2). pp. 194-7.

Hughes, David C, Legan, P Kevin, Steel, Karen P and Richardson, Guy P (1998) Mapping of the alpha-tectorin gene (TECTA) to mouse chromosome 9 and human chromosome 11: a candidate for human autosomal dominant nonsyndromic deafness. Genomics, 48 (1). pp. 46-51. ISSN 08887543

Rau, A, Legan, P K and Richardson, G P (1998) Expression of tectorin mRNAs during mouse inner ear development. British Journal of Audiology, 32 (2). pp. 73-74. ISSN 03005364

Legan, Kevin, Richardson, Guy, Kruger, Robert and Goodyear, Richard (1998) Identification and molecular cloning of proteins associated with the apical surfaces of hair and supporting cells. British Journal of Audiology, 32 (2). pag 123. ISSN 03005364

Verhoeven, Kristien, Van Laer, Lut, Kirschhofer, Karin, Legan, P Kevin, Hughes, David C, Schatteman, Isabelle, Verstreken, Margriet, Van Hauwe, Peter Van, Coucke, Paul, Chen, Achih, Smith, Richard J H, Somers, Thomas, Offeciers, F Erwin, Van de Heyning, Paul, Richardson, Guy P, Wachtler, Franz, Kimberling, William J, Willems, Patrick J, Govaerts, Paul J and Van Camp, Guy (1998) Mutations in the human a-tectorin gene cause autosomal dominant non- syndromic hearing impairment. Nature Genetics, 19 (1). pp. 60-62. ISSN 10614036

Coutinho, P, Goodyear, R, Legan, P K and Richardson, G P (1998) Molecular cloning of chick alpha-tectorin and its expression during embryogenesis. British Journal of Audiology, 32 (2). p. 72. ISSN 03005364

Legan, P K and Richardson, G P (1997) Extracellular matrix and cell adhesion molecules in the developing inner ear. Seminars in Cell and Developmental Biology, 8 (3). pp. 217-224. ISSN 1084-9521

Legan, P Kevin, Rau, Angela, Keen, Jeff N and Richardson, Guy P (1997) The mouse tectorins: modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system. Journal of Biological Chemistry, 272 (13). pp. 8791-8801. ISSN 00219258

Goodyear, R, Killick, R, Legan, P K and Richardson, G P (1996) Distribution of beta-tectorin mRNA in the early posthatch and developing avian inner ear. Hearing Research, 96 (1-2). pp. 167-78.

Killick, R, Legan, P K, Malenczak, C and Richardson, G P (1995) Molecular cloning of chick beta-tectorin, an extracellular matrix molecule of the inner ear. Journal of Cell Biology, 129 (2). pp. 535-547. ISSN 0021-9525

Book Section

Legan, P Kevin, Goodyear, Richard J, Van Camp, Guy and Richardson, Guy P (2004) Alpha-tectorin. In: Willems, Patrick J (ed.) Genetic Hearing Loss. Marcel Dekker Inc, pp. 291-306. ISBN 9780824743093