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Agnarelli, Alessandro, Lauer Betran, Andrea, Papakyriakou, Athanasios, Vella, Viviana, Samuels, Mark, Papanastasopoulos, Panagiotis, Giamas, Christina, Mancini, Erika J, Stebbing, Justin, Spencer, John, Cilibrasi, Chiara, Ditsiou, Angeliki and Giamas, Georgios (2023) The inhibitory properties of a novel, selective LMTK3 kinase inhibitor. International Journal of Molecular Sciences, 24 (1). e865 1-15. ISSN 1661-6596

Liang, Fei, Peng, Ling, Wu, Zhengyu, Giamas, Georgios and Stebbing, Justin (2022) Design and reporting of phase III oncology trials with prospective biomarker validation. Journal of the National Cancer Institute. djac210 1-7. ISSN 0027-8874

Agnarelli, Alessandro, Vella, Viviana, Samuels, Mark, Papanastasopoulos, Panagiotis and Giamas, Georgios (2022) Incorporating immunotherapy in the management of gastric cancer: molecular and clinical implications. Cancers, 14 (18). e4378 1-25. ISSN 2072-6694

Lane, Rosemary, Cilibrasi, Chiara, Chen, Jianing, Shah, Kalpit, Messuti, Eleonora, Mazarakis, Nektarios K, Stebbing, Justin, Critchley, Giles, Song, Erwei, Simon, Thomas and Giamas, Georgios (2022) PDGF-R inhibition induces glioblastoma cell differentiation via DUSP1/p38MAPK signalling. Oncogene. pp. 1-15. ISSN 0950-9232

Wang, Zhiqiang, Zhu, Liping, Li, Kesang, Sun, Yilan, Giamas, Georgios, Stebbing, Justin, Peng, Ling and Yu, Zhentao (2022) Alternative splicing events in tumor immune infiltration in renal clear cell carcinomas. Cancer Gene Therapy. ISSN 0929-1903

Brown, Christopher J, Simon, Thomas, Cilibrasi, Chiara, Lynch, Peter J, Harries, Rhiannon W, Amorim Graf, Aline, Large, Matthew J, Ogilvie, Sean P, Salvage, Jonathan P, Dalton, Alan B, Giamas, Georgios and King, Alice A K (2022) Tunable synthetic reduced graphene oxide scaffolds elicit high levels of three-dimensional glioblastoma connectivity in vitro. Journal of Materials Chemistry B: Materials for biology and medicine, 10 (3). pp. 373-383. ISSN 2050-750X

Brown, Christopher J, Simon, Thomas, Cilibrasi, Chiara, Lynch, Peter J, Harries, Rhiannon W, Graf, Aline Amorim, Large, Matthew J, Ogilvie, Sean P, Salvage, Jonathan P, Dalton, Alan B, Giamas, Georgios and King, Alice A K (2022) Tuneable synthetic reduced graphene oxide scaffolds elicit high levels of three-dimensional glioblastoma interconnectivity in vitro. Journal of Materials Chemistry B, 10 (30). pp. 373-383. ISSN 2050-750X

Samuels, Mark, Cilibrasi, Chiara, Papanastasopoulos, Panagiotis and Giamas, Georgios (2022) Extracellular vesicles as mediators of therapy resistance in breast cancer microenvironment. Biomolecules, 12 (1). pp. 1-40. ISSN 2218-273X

Cilibrasi, Chiara, Simon, Thomas, Vintu, Marian, Tolias, Christos, Samuels, Mark, Mazarakis, Nektarios K, Eravci, Murat, Stewart, Nicolas, Critchley, Giles and Giamas, Georgios (2022) Definition of an inflammatory biomarker signature in plasma-derived extracellular vesicles of glioblastoma patients. Biomedicines, 10 (1). a125 1-15. ISSN 2227-9059

Giamas, Georgios and Gagliano, Teresa (2022) Cancer gene therapy 2020: highlights from a challenging year. Cancer Gene Therapy, 29 (1). pp. 1-3. ISSN 0929-1903

Zhu, Liping, Wang, Zhiqiang, Sun, Yilan, Giamas, Georgios, Stebbing, Justin, Yu, Zhentao and Peng, Ling (2021) A prediction model using alternative splicing events and the immune microenvironment signature in lung adenocarcinoma. Frontiers in Oncology, 11. a778637 1-14. ISSN 2234-943X

Vella, Viviana, Giamas, Georgios and Ditsiou, Angeliki (2021) Diving into the dark kinome: lessons learned from LMTK3. Cancer Gene Therapy. ISSN 0929-1903

Lepore, Alessio, Choy, Pui Man, Lee, Nathan C W, Carella, Maria Annunziata, Favicchio, Rosy, Briones-Orta, Marco A, Glaser, Shannon S, Alpini, Gianfranco, D’Santos, Clive, Tooze, Reuben M, Lorger, Mihaela, Syn, Wing-Kin, Papakyriakou, Athanasios, Giamas, Georgios, Bubici, Concetta and Papa, Salvatore (2021) Phosphorylation and stabilization of PIN1 by JNK promote intrahepatic cholangiocarcinoma growth. Hepatology, 74 (5). pp. 2561-2579. ISSN 0270-9139

Cilibrasi, Chiara, Papanastasopoulos, Panagiotis, Samuels, Mark and Giamas, Georgios (2021) Reconstituting immune surveillance in breast cancer: molecular pathophysiology and current immunotherapy strategies. International Journal of Molecular Sciences, 22 (21). a12015 1-20. ISSN 1661-6596

Peng, Ling, Li, Jisheng, Wu, Jie, Xu, Bin, Wang, Zhiqiang, Giamas, Georgios, Stebbing, Justin and Yu, Zhentao (2021) A pan-cancer analysis of SMARCA4 alterations in human cancers. Frontiers in Immunology, 12. a762598 1-15. ISSN 1664-3224

Burn, Layla, Gutowski, Nicholas, Whatmore, Jacqueline, Giamas, Georgios and Pranjol, Md Zahidul Islam (2021) The role of astrocytes in brain metastasis at the interface of circulating tumour cells and the blood brain barrier. Frontiers in Bioscience-Landmark, 26 (9). pp. 590-601. ISSN 1093-9946

Wendler, Franz, Purice, Teodora-Maria, Simon, Thomas, Stebbing, Justin and Giamas, Georgios (2021) The LMTK-family of kinases: emerging important players in cell physiology and pathogenesis. BBA - Molecular Basis of Disease, 1867 (9). a165372 1-7. ISSN 0925-4439

Ditsiou, Angeliki, Gagliano, Teresa, Samuels, Mark, Vella, Viviana, Tolias, Christos and Giamas, Georgios (2021) The multifaceted role of lemur tyrosine kinase 3 in health and disease. Open biology, 11 (9). pp. 1-12. ISSN 2046-2441

Chrysostomou, Stelios, Roy, Rajat, Prischi, Filippo, Thamlikitkul, Lucksamon, Chapman, Kathryn L, Mufti, Uwais, Peach, Robert, Ding, Laifeng, Hancock, David, Moore, Christopher, Molina-Arcas, Miriam, Mauri, Francesco, Pinato, David J, Castellano, Leandro, Giamas, Georgios and others, (2021) Repurposed floxacins targeting RSK4 prevent chemoresistance and metastasis in lung and bladder cancer. Science Translational Medicine, 13 (602). ISSN 1946-6234

Cilibrasi, Chiara, Ditsiou, Angeliki, Papakyriakou, Athanasios, Mavridis, George, Eravci, Murat, Stebbing, Justin, Gagliano, Teresa and Giamas, Georgios (2021) Correction to: LMTK3 inhibition affects microtubule stability. Molecular Cancer, 20 (1). a65 1-3. ISSN 1476-4598

Cilibrasi, Chiara, Ditsiou, Angeliki, Papakyriakou, Athanasios, Mavridis, George, Eravci, Murat, Stebbing, Justin, Gagliano, Teresa and Giamas, Georgios (2021) LMTK3 inhibition affects microtubule stability. Molecular Cancer, 20. a53 1-6. ISSN 1476-4598

Klionsky, Daniel J, Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie H, Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis E, Adeli, Khosrow, Adolph, Timon E, Adornetto, Annagrazia, Giamas, Georgios and others, (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. pp. 1-382. ISSN 1554-8627

Ditsiou, Angeliki, Cilibrasi, Chiara, Simigdala, Nikiana, Harris, Leanne, Vella, Viviana, Gagliano, Teresa, Iachini, Maria Chiara, Simon, Thomas, Zhou, Lihong, Hassell-Hart, Storm, Pearl, Laurence H, Roe, S Mark, Spencer, John, Prodromou, Chrisostomos, Giamas, Georgios and others, (2020) The structure-function relationship of oncogenic LMTK3. Science Advances, 6 (46). pp. 1-19. ISSN 2375-2548

Shah, Kalpit, Gagliano, Teresa, Garland, Lisa, O’Hanlon, Timothy, Bortolotti, Daria, Gentili, Valentina, Rizzo, Roberta, Giamas, Georgios and Dean, Michael (2020) Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing. Oncogene. ISSN 0950-9232

Harries, Rhiannon W, Brown, Christopher J, Ogilvie, Sean P, Large, Matthew J, Amorim Graf, Aline, Clifford, Keiran, Simon, Thomas, Giamas, Georgios, Dalton, Alan B and King, Alice A K (2020) Langmuir films of layered nanomaterials: edge interactions and cell culture applications. Journal of Physical Chemistry B. ISSN 1520-5207

Gagliano, Teresa, Shah, Kalpit, Gargani, Sofia, Lao, Liyan, Alsaleem, Mansour, Chen, Jianing, Ntafis, Vasileios, Huang, Penghan, Ditsiou, Angeliki, Vella, Viviana, Yadav, Kritika, Bienkowska, Kamila, Benstead-Hum, Graeme, Pearl, Frances M G, Giamas, Georgios and others, (2020) PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression. Journal of Clinical Investigation, 130 (6). pp. 3188-3204. ISSN 0021-9738

Simon, Thomas, Jackson, Ellen and Giamas, Georgios (2020) Breaking through the glioblastoma micro-environment via extracellular vesicles. Oncogene. pp. 1-14. ISSN 0950-9232

Simon, Thomas, Kumaran, Anish, Veselu, Diana-Florentina and Giamas, Georgios (2020) Three method-combination protocol for improving purity of extracellular vesicles. International Journal of Molecular Sciences, 21 (9). a3071. ISSN 1661-6596

Martelli, Costanza, King, Alice, Simon, Thomas and Giamas, Georgios (2020) Graphene-induced transdifferentiation of cancer stem cells as a therapeutic strategy against glioblastoma. ACS Biomaterials Science & Engineering. ISSN 2373-9878

Giamas, Georgios (2020) [Editorial] Cancer gene therapy: vision and strategy for the new decade. Cancer Gene Therapy, 27. p. 115. ISSN 0929-1903

Giamas, Georgios (2020) Reviewer recognition. Cancer gene therapy, 27. a264. ISSN 0929-1903

Bresciani, Giulia, Hofland, Leo J, Dogan, Fadime, Giamas, Georgios, Gagliano, Teresa and Zatelli, Maria Chiara (2019) Evaluation of spheroid 3D culture methods to study a pancreatic neuroendocrine neoplasm cell line. Frontiers in Endocrinology, 10. a682 1-10. ISSN 1664-2392

Lane, Rosemary, Simon, Thomas, Vintu, Marian, Solkin, Benjamin, Koch, Barbara, Stewart, Nicolas, Benstead-Hume, Graeme, Pearl, Frances M G, Critchley, Giles, Stebbing, Justin and Giamas, Georgios (2019) Cell-derived extracellular vesicles can be used as a biomarker reservoir for glioblastoma tumor subtyping. Communications Biology, 2. a315. ISSN 2399-3642

Rani, Aradhana, Stebbing, Justin, Giamas, Georgios and Murphy, John (2019) Endocrine resistance in hormone receptor positive breast cancer–from mechanism to therapy. Frontiers in Endocrinology, 10 (245). pp. 1-32. ISSN 1664-2392

Bresciani, Giulia, Ditsiou, Angeliki, Cilibrasi, Chiara, Vella, Viviana, Rea, Federico, Schiavon, Marco, Cavallesco, Narciso Giorgio, Giamas, Georgios, Zatelli, Maria Chiara and Gagliano, Teresa (2019) EGF and IGF1 affect Sunitinib activity in BP-NEN: new putative targets beyond VEGFR? Endocrine Connections, 8 (6). pp. 680-690. ISSN 2049-3614

Brandao, Mayra, Simon, Thomas, Critchley, Giles and Giamas, Georgios (2019) Astrocytes, the rising stars of the glioblastoma microenvironment. Glia, 67 (5). pp. 779-790. ISSN 0894-1491

Simon, Thomas, Pinioti, Sotiria, Schellenberger, Pascale, Rajeeve, Vinothini, Wendler, Franz, Cutillas, Pedro R, King, Alice, Stebbing, Justin and Giamas, Georgios (2018) [Letter to editor] Shedding of bevacizumab in tumour cells derived extracellular vesicles as a new therapeutic escape mechanism in glioblastoma. Molecular Cancer, 17 (132). pp. 1-7. ISSN 1476-4598

Stebbing, Justin, Shah, Kalpit, Lit, Lei Cheng, Gagliano, Teresa, Ditsiou, Angeliki, Wang, Tingting, Wendler, Franz, Simon, Thomas, Szabo, Krisztina Sára, O’Hanlon, Timothy, Dean, Michael, Roslani, April Camilla, Cheah, Swee Hung, Lee, Soo-Chin and Giamas, Georgios (2018) LMTK3 confers chemo-resistance in breast cancer. Oncogene, 37 (23). pp. 3113-3130. ISSN 1476-5594

Simon, Thomas, Gagliano, Teresa and Giamas, Georgios (2017) Direct effects of anti-angiogenic therapies on tumor cells: VEGF signaling. Trends in Molecular Medicine, 23 (3). pp. 282-292. ISSN 1471-4914

Wendler, F, Favicchio, R, Simon, T, Alifrangis, C, Stebbing, J and Giamas, G (2017) Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention. Oncogene, 36 (7). pp. 877-884. ISSN 0950-9232

Gagliano, Teresa, Simon, Thomas and Giamas, Georgios (2016) miRNA transported by exosomes: a key machinery in tumor microenvironment mediated chemoresistance. Translational Cancer Research, 5 (S7). S1479-S1482. ISSN 2218-676X

Angelopoulos, Nicos, Abdallah, Samer and Giamas, Georgios (2016) Advances in integrative statistics for logic programming. International Journal of Approximate Reasoning, 78. pp. 103-115. ISSN 0888-613X

Favicchio, Rosy, Thepaut, Chloe, Zhang, Hua, Arends, Richard, Stebbing, Justin and Giamas, Georgios (2016) Strategies in functional proteomics: unveiling the pathways to precision oncology. Cancer Letters, 382 (1). pp. 86-94. ISSN 0304-3835

Wendler, Franz, Stamp, Gordon and Giamas, Georgios (2016) Tumor–stromal cell communication: small vesicles signal big changes. Trends in Cancer, 2 (7). pp. 326-329. ISSN 2405-8033

Angelopoulos, Nicos, Stebbing, Justin, Xu, Yichen, Giamas, Georgios and Zhang, Hua (2016) Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer. Data in Brief, 7. pp. 740-746. ISSN 2352-3409

Rampias, T, Favicchio, R, Stebbing, J and Giamas, G (2016) Targeting tumor-stroma crosstalk: the example of the NT157 inhibitor. Oncogene, 35 (20). pp. 2562-2564. ISSN 0950-9232

Nunes, Joao, Zhang, Hua, Angelopoulos, Nicos, Chhetri, Jyoti, Osipo, Clodia, Grothey, Arnhild, Stebbing, Justin and Giamas, Georgios (2016) ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation. Oncotarget, 7 (19). pp. 27599-27612. ISSN 1949-2553

Jacob, Jimmy, Favicchio, Rosa, Karimian, Negin, Mehrabi, Maryam, Harding, Victoria, Castellano, Leandro, Stebbing, Justin and Giamas, Georgios (2016) LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5. Cancer Letters, 372 (1). pp. 137-146. ISSN 0304-3835

Schofield, G M, Urch, C E, Stebbing, J and Giamas, G (2016) Reply: when does a human being die? QJM, 109 (2). p. 146. ISSN 1460-2725

Xu, Yichen, Zhang, Hua, Nguyen, Van, Angelopoulos, Nikos, Nunes, Joao, Reid, Alistair, Buluwela, Laki, Magnani, Luca, Stebbing, Justin and Giamas, Georgios (2015) LMTK3 represses tumor suppressor-like genes through chromatin remodeling in breast cancer. Cell Reports, 12 (5). pp. 837-849. ISSN 2211-1247

Stebbing, Justin, Zhang, Hua, Xu, Yichen, Grothey, Arnhild, Ajuh, Paul, Angelopoulos, Nicos and Giamas, Georgios (2015) Reprogramming of the tyrosine kinase-regulated proteome in breast cancer by combined use of RNAi and SILAC quantitative proteomics. Molecular and Cellular Proteomics : MCP, 14. pp. 2479-2492. ISSN 1535-9484

Zhang, Hua, Angelopoulos, Nicos, Xu, Yichen, Grothey, Arnhild, Nunes, Joao, Stebbing, Justin and Giamas, Georgios (2015) Proteomic profile of KSR1-regulated signalling in response to genotoxic agents in breast cancer. Breast Cancer Research and Treatment, 151 (3). pp. 555-568. ISSN 0167-6806

Stebbing, J, Zhang, H, Xu, Y, Lit, L C, Green, A R, Grothey, A, Lombardo, Y, Periyasamy, M, Blighe, K, Zhang, W, Shaw, J A, Ellis, I O, Lenz, H J and Giamas, G (2015) KSR1 regulates BRCA1 degradation and inhibits breast cancer growth. Oncogene, 34 (16). pp. 2103-2114. ISSN 1476-5594

Papanastasopoulos, Panos and Giamas, Georgios (2015) mTOR inhibition in breast cancer. Breast Cancer Management, 4 (2). pp. 67-70. ISSN 1758-1923

Schofield, G M, Urch, C E, Stebbing, J and Giamas, G (2015) When does a human being die? QJM: An International Journal of Medicine, 108 (8). pp. 605-609. ISSN 1460-2725

Benhaim, L, Zhang, W, Wakatsuki, T, Yang, D, Gerger, A, Bohanes, P, Paez, D, Loupakis, F, LaBonte, M J, Ning, Y, El-Khoueiry, R, Ladner, R, Wilson, P, Zhang, H, Giamas, G, Stebbing, J and Lenz, H J (2015) Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer. The Pharmacogenomics Journal, 15 (3). pp. 235-240. ISSN 1470-269X

Zhang, Hua, Stebbing, Justin and Giamas, Georgios (2015) The many-faced KSR1: a tumor suppressor in breast cancer. Oncoscience, 2 (8). pp. 669-670. ISSN 2331-4737

Zhang, Hua, Xu, Yichen, Papanastasopoulos, Panos, Stebbing, Justin and Giamas, Georgios (2014) Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer. Expert Review of Proteomics, 11 (6). pp. 713-731. ISSN 1478-9450

Xu, Yichen, Zhang, Hua and Giamas, Georgios (2014) Targeting lemurs against cancer metastasis. Oncotarget, 5 (14). pp. 5192-5193. ISSN 1949-2553

Xu, Yichen, Zhang, Hua, Lit, Lei C, Grothey, Arnhild, Athanasiadou, Maria, Kiritsi, Marianna, Lombardo, Ylenia, Frampton, Adam E, Green, Andrew R, Ellis, Ian O, Ali, Simak, Lenz, Heinz-Josef, Thanou, Maya, Stebbing, Justin and Giamas, Georgios (2014) The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin β₁. Science signaling, 7 (330). ra58. ISSN 1937-9145

Stebbing, J, Lit, L C, Zhang, H, Darrington, R S, Melaiu, O, Rudraraju, B and Giamas, G (2014) The regulatory roles of phosphatases in cancer. Oncogene, 33 (8). pp. 939-953. ISSN 1476-5594

Winder, T, Giamas, G, Wilson, P M, Zhang, W, Yang, D, Bohanes, P, Ning, Y, Gerger, A, Stebbing, J and Lenz, H-J (2014) Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen. The Pharmacogenomics Journal, 14 (1). pp. 28-34. ISSN 1473-1150

Melaiu, Ombretta, Stebbing, Justin, Lombardo, Ylenia, Bracci, Elisa, Uehara, Norihisa, Bonotti, Alessandra, Cristaudo, Alfonso, Foddis, Rudy, Mutti, Luciano, Barale, Roberto, Gemignani, Federica, Giamas, Georgios and Landi, Stefano (2014) MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma. PLoS ONE, 9 (1). e85935. ISSN 1932-6203

Fentiman, Ian, Cartlidge, Christopher, Dixon, J Michael, Giamas, Georgios and Kiritsi, Marianna (2013) Journal Watch: Our panel of experts highlight the most important research articles across the spectrum of topics relevant to the field of breast cancer management. Breast Cancer Management, 2 (6). pp. 455-457. ISSN 1758-1923

Stebbing, J, Filipović, A and Giamas, G (2013) Claudin-1 as a promoter of EMT in hepatocellular carcinoma. Oncogene, 32 (41). pp. 4871-4872. ISSN 0950-9232

Wakatsuki, Takeru, LaBonte, Melissa J, Bohanes, Pierre O, Zhang, Wu, Yang, Dongyun, Azuma, Mizutomo, Barzi, Afsaneh, Ning, Yan, Loupakis, Fotios, Saadat, Siamak, Volz, Nico, Stintzing, Sebastian, El-Khoueiry, Rita, Koizumi, Wasaburo, Watanabe, Masahiko, Shah, Manish, Stebbing, Justin, Giamas, Georgios and Lenz, Heinz-Josef (2013) Prognostic role of lemur tyrosine kinase-3 germline polymorphisms in adjuvant gastric cancer in Japan and the United States. Molecular Cancer Therapeutics, 12 (10). pp. 2261-2272. ISSN 1535-7163

Zhang, Hua, Koo, Chuay Yeng, Stebbing, Justin and Giamas, Georgios (2013) The dual function of KSR1: a pseudokinase and beyond. Biochemical Society Transactions, 41 (4). pp. 1078-82. ISSN 0300-5127

Stebbing, J, Filipovic, A, Lit, L C, Blighe, K, Grothey, A, Xu, Y, Miki, Y, Chow, L W, Coombes, R C, Sasano, H, Shaw, J A and Giamas, G (2013) LMTK3 is implicated in endocrine resistance via multiple signaling pathways. Oncogene, 32 (28). pp. 3371-3380. ISSN 0950-9232

Filipovic, Aleksandra, Stebbing, Justin and Giamas, Georgios (2013) Cancer stem cells - therapeutic targeting or therapy? Lancet Oncology, 14 (7). pp. 579-580. ISSN 1470-2045

Lit, Lei Cheng, Scott, Susan, Zhang, Hua, Stebbing, Justin, Photiou, Andrew and Giamas, Georgios (2013) LATS2 is a modulator of estrogen receptor alpha. Anticancer Research, 33 (1). pp. 53-63. ISSN 0250-7005

Zhang, H, Xu, Y, Filipovic, A, Lit, L C, Koo, C-Y, Stebbing, J and Giamas, G (2013) SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1. British Journal of Cancer, 109 (10). pp. 2675-2684. ISSN 1532-1827

Lombardo, Ylenia, Filipović, Aleksandra, Molyneux, Gemma, Periyasamy, Manikandan, Giamas, Georgios, Hu, Yunhui, Trivedi, Pritesh S, Wang, Jayson, Yagüe, Ernesto, Michel, Loren and Coombes, R Charles (2012) Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo. Proceedings of the National Academy of Sciences, 109 (41). pp. 16558-16563. ISSN 1091-6490

Xu, Yichen and Giamas, Georgios (2012) [Editorial] Breast cancer and LMTK3: old disease, new target. Breast Cancer Management, 1 (2). pp. 101-103. ISSN 1758-1923

Zhang, Hua, Photiou, Andrew, Grothey, Arnhild, Stebbing, Justin and Giamas, Georgios (2012) The role of pseudokinases in cancer. Cellular Signalling, 24 (6). pp. 1173-1184. ISSN 0898-6568

Schirripa, Marta, Loupakis, Fotios, Cremolini, Chiara, Yang, Dongyun, Labonte, Melissa Janae, Zhang, Wu, Salvatore, Lisa, Wakatsuki, Takeru, El-Khoueiry, Rita, Antoniotti, Carlotta, Aprile, Giuseppe, Maus, Martin Karl Herbert, Lucchesi, Sara, Allegrini, Giacomo, De Vita, Fernando, Zhang, Hua, Giamas, Georgios, Stebbing, Justin, Falcone, Alfredo and Lenz, Heinz-Josef (2012) KSR1 gene polymorphism in mCRC patients treated with first-line FOLFIRI and bevacizumab. Journal of Clinical Oncology, 30 (15). p. 3546. ISSN 0732-183X

Stebbing, Justin, Filipovic, Aleksandra, Ellis, Ian O, Green, Andrew R, D'Silva, Tanya Rapoz, Lenz, Heinz-Josef, Coombes, R Charles, Wang, Tingting, Lee, Soo-Chin and Giamas, Georgios (2012) LMTK3 expression in breast cancer: association with tumor phenotype and clinical outcome. Breast Cancer Research and Treatment, 132 (2). pp. 537-544. ISSN 0167-6806

Jiao, Long R, Frampton, Adam E, Jacob, Jimmy, Pellegrino, Loredana, Krell, Jonathan, Giamas, Georgios, Tsim, Nicole, Vlavianos, Panagiotis, Cohen, Patrizia, Ahmad, Raida, Keller, Andreas, Habib, Nagy A, Stebbing, Justin and Castellano, Leandro (2012) MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors. PLoS ONE, 7 (2). e32068. ISSN 1932-6203

Filipović, A, Giamas, G and Stebbing, J (2011) The potential role of cyclooxygenase-2 (COX-2) during early breast cancer therapy. Annals of Oncology, 22 (8). pp. 1700-1702. ISSN 0923-7534

Giamas, G (2011) LMTK3: a novel therapeutic target for breast cancer. Pharmacogenomics, 12 (7). pp. 931-932. ISSN 1462-2416

Stebbing, Justin, Filipović, Aleksandra and Giamas, Georgios (2011) Lemur tyrosine kinase-3 (LMTK3) in cancer and evolution. Oncotarget, 2 (6). pp. 428-9. ISSN 1949-2553

Stebbing, Justin, Filipović, Aleksandra and Giamas, Georgios (2011) [Editorial] LMTK3 and evolution. Oncotarget, 2. pp. 428-429. ISSN 1949-2553

Giamas, Georgios, Filipović, Aleksandra, Jacob, Jimmy, Messier, Walter, Zhang, Hua, Yang, Dongyun, Zhang, Wu, Shifa, Belul Assefa, Photiou, Andrew, Tralau-Stewart, Cathy, Castellano, Leandro, Green, Andrew R, Coombes, R Charles, Ellis, Ian O, Ali, Simak, Lenz, Heinz-Josef and Stebbing, Justin (2011) Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nature Medicine, 17 (6). pp. 715-719. ISSN 1546-170X

Filipović, Aleksandra, Giamas, Georgios, Coombes, R Charles and Stebbing, Justin (2010) Gamma secretase and Notch as therapeutic targets in cancer. Advances in Breast Cancer, 7 (3). pp. 2-5. ISSN 1742-0946

Man, Y L, Filipović, A, Stebbing, J and Giamas, G (2010) New and established targets for the treatment of breast cancer. Advances in Breast Cancer, 7 (3). pp. 10-13. ISSN 1742-0946

Giamas, Georgios, Man, Yik L, Hirner, Heidrun, Bischof, Joachim, Kramer, Klaus, Khan, Kalimullah, Ahmed, Sharmeen S Lavina, Stebbing, Justin and Knippschild, Uwe (2010) Kinases as targets in the treatment of solid tumors. Cellular Signalling, 22 (7). pp. 984-1002. ISSN 0898-6568

Castellano, Leandro, Giamas, Georgios, Jacob, Jimmy, Coombes, R Charles, Lucchesi, Walter, Thiruchelvam, Paul, Barton, Geraint, Jiao, Long R, Wait, Robin, Waxman, Jonathan, Hannon, Gregory J and Stebbing, Justin (2009) The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proceedings of the National Academy of Sciences, 106 (37). pp. 15732-15737. ISSN 1091-6490

Giamas, Georgios, Castellano, Leandro, Feng, Qin, Knippschild, Uwe, Jacob, Jimmy, Thomas, Ross S, Coombes, R Charles, Smith, Carolyn L, Jiao, Long R and Stebbing, Justin (2009) CK1δ modulates the transcriptional activity of ERα via AIB1 in an estrogen-dependent manner and regulates ERα-AIB1 interactions. Nucleic Acids Research, 37 (9). pp. 3110-3123. ISSN 0305-1048

Mintz, Paul J, Habib, Nagy A, Jones, Louise J, Giamas, Georgios, Lewis, Jacqueline S, Bowen, Rebecca L, Coombes, R Charles and Stebbing, Justin (2008) The phosphorylated membrane estrogen receptor and cytoplasmic signaling and apoptosis proteins in human breast cancer. Cancer, 113 (6). pp. 1489-1495. ISSN 0008-543X

Apostolopoulos, Christos, Castellano, Leandro, Stebbing, Justin and Giamas, Georgios (2008) Bendamustine as a model for the activity of alkylating agents. Future Oncology, 4 (3). pp. 323-332. ISSN 1479-6694

Brockschmidt, C, Hirner, H, Huber, N, Eismann, T, Hillenbrand, A, Giamas, G, Radunsky, B, Ammerpohl, O, Bohm, B, Henne-Bruns, D, Kalthoff, H, Leithäuser, F, Trauzold, A and Knippschild, U (2008) Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo. Gut, 57 (6). pp. 799-806. ISSN 0017-5749

von Blume, J, Knippschild, Uwe, Dequiedt, Franck, Giamas, Georgios, Beck, Alexander, Auer, Alexandra, Van Lint, Johan, Adler, Guido and Seufferlein, Thomas (2007) Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2. EMBO Journal, 26 (22). pp. 4619-4633. ISSN 0261-4189

Apostolopoulos, Christos, Giamas, Georgios and Stebbing, Justin (2007) Clinical significance of circulating tumor cells. Biomarkers in Medicine, 1 (3). pp. 341-342. ISSN 1752-0363

Giamas, Georgios, Hirner, Heidrun, Shoshiashvili, Levani, Grothey, Arnhild, Gessert, Susanne, Kühl, Michael, Henne-Bruns, Doris, Vorgias, Constantinos E and Knippschild, Uwe (2007) Phosphorylation of CK1δ: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo. Biochemical Journal, 406 (3). pp. 389-398. ISSN 0264-6021

Giamas, Georgios, Stebbing, Justin, Vorgias, Constantinos E and Knippschild, Uwe (2007) Protein kinases as targets for cancer treatment. Pharmacogenomics, 8 (8). pp. 1005-1016. ISSN 1462-2416

Wolff, Sonja, Stöter, Martin, Giamas, Georgios, Piesche, Matthias, Henne-Bruns, Doris, Banting, George and Knippschild, Uwe (2006) Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin. FEBS Letters, 580 (27). pp. 6477-6484. ISSN 0014-5793

Knippschild, Uwe, Wolff, Sonja, Giamas, Georgios, Brockschmidt, Claas, Wittau, Mathias, Würl, Peter Uwe, Eismann, Thorsten and Stöter, Martin (2005) The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development. Onkologie, 28 (10). pp. 508-514. ISSN 0378-584X

Conference or Workshop Item

Thaker, Premal, Flint, Melanie, Giamas, Georgios, Falcinelli, Marta, Alhity, Gheed, Mampay, Myrthe, Allen, Marcus, Cilibrasi, Chiara and Samuels, Mark (2022) Pharmacologic inhibition of beta-adrenergic receptors decreases PD-L1 mediated immunosuppression and improves anti-tumor immune signature in ovarian cancer (126). In: Abstracts of the 2022 Society of Gynecologic Oncology Annual Meeting, 18-21 March 2022, Phoenix, Arizona.

Bresciani, Giulia, Hofland, Leo J, Giamas, Georgios, Gagliano, Teresa and Zatelli, Maria Chiara (2019) Available 3D cultures methods: study on a Pancreatic Neuroendocrine Neoplasm cell line. In: 21st European Congress of Endocrinology, 18th May - 21nd May 2019, Lyon, France.

Bresciani, Giulia, Ditsiou, Angeliki, Cilibrasi, Chiara, Vella, Viviana, Rea, Federico, Schiavon, Marco, Cavallesco, Narciso Giorgio, Giamas, Georgios, Zatelli, Maria Chiara and Gagliano, Teresa (2019) EGFR and IGF1R affect Sunitinib activity: novel targets for Broncho-Pulmonary Neuroendocrine Neoplasm treatment. In: 21st European Congress of Endocrinology, 18th May - 21st May 2019, Lyon, France.

Bresciani, Giulia, Ditsiou, Angeliki, Cilibrasi, Chiara, Vella, Viviana, Giamas, Georgios, Zatelli, Maria Chiara and Gagliano, Teresa (2019) Influence of Tumor Microenviroment in response modulation to treatment in human BP-NENs. In: 21st European Congress of Endocrinology, 18th May - 21th May 2019, Lyon, France.

Gagliano, Teresa, Vella, Viviana, Bienkowska, Kamila, Ditsiou, Angeliki and Giamas, Georgios (2018) Fibroblast-kinome silencing to identifies putative mediator of Triple-negative breast cancer (TNBC) invasion. In: 20th European Congress of Endocrinology, 19th May - 22nd May 2018, Barcelona, Spain.

Ditsiou, Angeliki, Gagliano, Teresa, Prodromou, Chrisostomos, Gascon, Jose, Mumford, Sophie, Grand, Darren Le and Giamas, Georgios (2018) Targeting treatment resistance in breast cancer subtypes via LMTK3 inhibition. In: 20th European Congress of Endocrinology, 19-22 May 2018, Barcelona, Spain.

Gagliano, Teresa, Ditsiou, Angeliki, Grothey, Arnhild and Giamas, Georgios (2017) ER status heterogeneity in breast cancer: role in response to endocrine treatment. In: 19th European Congress of Endocrinology, 20th May - 23rd May 2017, Lisbon, Portugal.

Gagliano, Teresa, Ditsiou, Angeliki, Grothey, Arnhild and Giamas, Georgios (2016) Human kinome siRNA screening to identify novel targets implicated in fibroblast-mediated triple negative breast cancer cells invasion. In: EACR conference series goodbye flat biology: models, mechanisms and microenvironment, 2 - 5 october 2016, Berlin.

Schirripa, Marta, Loupakis, Fotios, Cremolini, Chiara, Dongyun, Yang, Labonte, Melissa Janae, Zhang, Wu, Salvatore, Lisa, Wakatsuky, Takeru, Antoniotti, Carlotta, Aprile, Giuseppe, Lucchesi, Sara, Giamas, Georgios, Justin, Stebbing, Falcone, Alfredo and Lenz, Heinz Joseph (2012) PD-0016 KSR1 gene polymorphism in mcrc patients treated with first-line folfiri and bevacizumab. In: ESMO 14th World Congress on Gastrointestinal Cancer, 27–30 June 2012, Barcelona, Spain.

Conference Proceedings

Giamas, Georgios, Cilibrasi, Chiara, Simon, Thomas, Stewart, Nicolas, Critchley, Giles and Eravci, Murat (2022) BIOM-06. Identification of an inflammatory biomarker signature in plasma-derived extracellular vesicles of glioblastoma patients. 2022 Society for Neuro-Oncology’s 27th Annual Scientific Meeting and Education Day, Tampa Bay, Florida, USA, 16-20 November 2022. Published in: Neuro-Oncology. 24 (7) vii5-vii5. Oxford University Press (OUP) ISSN 1522-8517

Angelopoulos, Nicos, Abdallah, Samer and Giamas, Georgios (2015) Advances in integrating statistical inference. Proceedings of the 2nd International Workshop on Probabilistic Logic Programming (PLP 2015), Cork, Ireland, August 31st, 2015. Published in: CEUR Workshop Proceedings. 1413 9-18. CEUR Workshop Proceedings ISSN 1613-0073

Xu, Yichen, Zhang, Hua, Vorgias, Constantinos, Stebbing, Justin and Giamas, Georgios (2014) Positioning LMTK3 on the map of oncogenic signaling cascades and elucidating its role in invasion and metastasis in breast cancer. Abstracts of the ninth international conference of anticancer research, Sithonia, Greece, October 6 - 10, 2014. Published in: Anticancer Research. 34 (10) 5923-5924. International Institute of Anticancer Research ISSN 0250-7005

Nunes, Joao Farinha Garcao, Zhang, Hua, Stebbing, Justin, Angelopoulos, Nicos and Giamas, Georgios (2014) Silac-based analysis reveals a unique phosphoproteomic-signature of her2-resistant breast cancer cells. Abstracts of the ninth international conference of anticancer research, Sithonia, Greece, October 6 - 10, 2014. Published in: Anticancer Research. 34 (10) 5900-5900. International Institute of Anticancer Research ISSN 0250-7005

Zhang, Wu, Benhaim, Leonor, Yang, Dongyun, Gerger, Armin, Bohanes, Pierre Oliver, Páez, David, Loupakis, Fotios, Wakatsuki, Takeru, Labonte, Melissa Janae, Ning, Yan, El-Khoueiry, Rita, Zhang, Hua, Stebbing, Justin, Giamas, Georgios and Lenz, Heinz-Josef (2012) Genetic variants of kinases suppressors of ras (KSR1) to predict survival in patients with ER-alpha positive metastatic breast cancer. 2012 Annual Meeting of the American Society of Clinical Oncology, Chicago, Illinois, June 01 - 05, 2012. Published in: Journal of Clinical Oncology. 30 (15) e11018. American Society of Clinical Oncology (ASCO) ISSN 0732-183X

Benhaim, Leonor, Loupakis, Fotios, Zhang, Wu, Gerger, Armin, Bohanes, Pierre Oliver, Páez, David, Cremolini, Chiara, Wakatsuki, Takeru, Yang, Dongyun, Ning, Yan, El-Khoueiry, Rita, Zhang, Hua, Salvatore, Lisa, Schirripa, Marta, Falcone, Alfredo, Giamas, Georgios, Stebbing, Justin and Lenz, Heinz-Josef (2012) Genetic variants of kinases suppressors of ras in KRAS-BRAF wild-type metastatic colorectal cancer patients treated with cetuximab and irinotecan. 2012 Annual Meeting of the American Society of Clinical Oncology, Chicago, Illinois, June 01 - 05 2012. Published in: Journal of Clinical Oncology. 30 (15) 3597-3597. American Society of Clinical Oncology (ASCO) ISSN 0732-183X

Barzi, Afsaneh, Wakatsuki, Takeru, Zhang, Wu, Yang, Dongyun, Loupakis, Fotios, Ning, Yan, El-Khoueiry, Rita, Labonte, Melissa Janae, Azuma, Mizutomo, Bohanes, Pierre Oliver, Benhaim, Leonor, Gerger, Armin, Koizumi, Wasaburo, Watanabe, Masahiko, Stebbing, Justin, Giamas, Georgios and Lenz, Heinz-Josef (2012) Prognostic value of lemur tyrosine kinase-3 (LMTK3) polymorphism in Japanese (J) patients (PTS) with localized gastric adenocarcinoma (GAC). 2012 Annual Meeting of the American Society of Clinical Oncology, Chicago, Illinois, June 01 - 05 2012. Published in: Journal of Clinical Oncology. 30 (15) 4088-4088. American Society of Clinical Oncology (ASCO) ISSN 0732-183X

Zhang, Wu, Gerger, Armin, Labonte, Melissa Janae, Yang, Dongyun, Bohanes, Pierre Oliver, Ning, Yan, Winder, Thomas, Wilson, Peter M D, Benhaim, Leonor, El-Khoueiry, Rita, El-Khoueiry, Anthony B, Iqbal, Syma, Giamas, Georgios, Stebbing, Justin and Lenz, Heinz-Josef (2012) Association of gender-related tumor recurrence with a polymorphic variant of LMTK3 in stage II and III colon cancer. Published in: Journal of Clinical Oncology. 30 (4) 454-454. American Society of Clinical Oncology ISSN 0732-183X

Wakatsuki, Takeru, Bohanes, Pierre Oliver, Zhang, Wu, Gerger, Armin, Yang, Dongyun, Ning, Yan, Winder, Thomas, Labonte, Melissa Janae, Wilson, Peter MD, Benhaim, Leonor, El-Khoueiry, Rita, El-Khoueiry, Anthony B, Iqbal, Syma, Giamas, Georgios, Stebbing, Justin and Lenz, Heinz-Josef (2012) Use of genetic variants of LMTK3 to predict tumor recurrence in female localized gastric adenocarcinoma. 2012 Gastrointestinal Cancers Symposium, San Francisco, California, January 19 - 21, 2012. Published in: Journal of Clinical Oncology. 30 (4) 63-63. American Society of Clinical Oncology ISSN 0732-183X

Winder, T, Giamas, G, Zhang, W, Yang, D, Bohanes, P O, Ning, Y, Gerger, A, Labonte, M J, Stebbing, J and Lenz, H (2011) Use of insulin-like growth factor (IGF) pathway polymorphism IGF1R_rs2016347 to predict tumor recurrence in estrogen receptor-positive breast cancer patients. 2011 ASCO Annual Meeting I, Chicago, Illinois, June 03 - June 07, 2011. Published in: Journal of Clinical Oncology. 29 (15) 538-538. American Society of Clinical Oncology ISSN 0732-183X

Castellano, L, Waxman, J, Giamas, G, Apostolopous, C and Stebbing, J (2008) The identification of new tumour suppressor micromas epigenetically silenced in drug resistant cancer cells. 20th Meeting of the European Association for Cancer Research, Lyon, France, 5-8 July 2008. Published in: European Journal of Cancer Supplements. 6 (9) 95-95. Elsevier ISSN 1359-6349

Giamas, G, Ali, S, Apostolopoulos, C, Castellano, L, Coombes, C and Stebbing, J (2008) The identification of new signaling pathways involved in estrogen receptor-alpha (ER alpha) transcriptional activity. Joint Conference of the 33rd FEBS Congress/11th IUBMB Conference, Athens, Greece, June 28 - July 03, 2008. Published in: FEBS JOURNAL. 275 137-137. ISSN 1742-464X

Patent

THE UNIVERSITY OF SUSSEX [GB/GB]; Sussex House Falmer Brighton Sussex BN1 9RH (GB) (2022) Small molecule inhibitors of Lemur tyrosine kinase 3 (LTK). .

This list was generated on Thu Feb 2 08:09:30 2023 GMT.