Items for Bloomfield, Graham

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Number of items: 18.


Cox, Brian, Zdorichenko, Victor, Cox, Philip B, Booker-Milburn, Kevin I, Paumier, Romain, Elliott, Luke D, Robertson-Ralph, Michael and Bloomfield, Graham (2020) Escaping from flatland: substituted bridged pyrrolidine fragments with inherent three-dimensional character. ACS Medicinal Chemistry Letters, 11 (6). pp. 1185-1190. ISSN 1948-5875

Bruce, Ian, Akhlaq, Mohammed, Bloomfield, Graham C, Budd, Emma, Cox, Brian, Cuenoud, Bernard, Finan, Peter, Gedeck, Peter, Hatto, Julia, Hayler, Judy F, Head, Denise, Keller, Thomas, Kirman, Louise, Leblanc, Catherine, Le Grand, Darren, McCarthy, Clive, O'Connor, Desmond, Owen, Charles, Oza, Mrinalini S, Pilgrim, Gaynor, Press, Nicola E, Sviridenko, Lilya and Whitehead, Lewis (2012) Development of isoform selective PI3-kinase inhibitors as pharmacological tools for elucidating the PI3K pathway. Bioorganic and Medicinal Chemistry Letters, 22 (17). pp. 5445-5450. ISSN 0960-894X

Coote, K, Atherton-Watson, H C, Sugar, R, Young, A, MacKenzie-Beevor, A, Gosling, M, Bhalay, G, Bloomfield, G, Dunstan, A, Bridges, R J, Sabater, J R, Abraham, W M, Tully, D, Pacoma, R, Schumacher, A, Harris, J and Danahay, H (2009) Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease. Journal of Pharmacology and Experimental Therapeutics, 329 (2). pp. 764-774. ISSN 0022-3565

Ritchie, Timothy J, Dziadulewicz, Edward K, Culshaw, Andrew J, Müller, Werner, Burgess, Gillian M, Bloomfield, Graham C, Drake, Gillian S, Dunstan, Andrew R, Beattie, David, Hughes, Glyn A, Ganju, Pam, McIntyre, Peter, Bevan, Stuart J, Davis, Clare and Yaqoob, Mohammed (2004) Potent and orally bioavailable non-peptide antagonists at the human bradykinin B1 receptor based on a 2-Alkylamino-5-sulfamoylbenzamide core. Journal of Medicinal Chemistry, 47 (19). pp. 4642-4644. ISSN 0022-2623

Dziadulewicz, Edward K, Ritchie, Timothy J, Hallett, Allan, Snell, Christopher R, Davies, John W, Wrigglesworth, Roger, Dunstan, Andrew R, Bloomfield, Graham C, Drake, Gillian S, McIntyre, Peter, Brown, Michael C, Burgess, Gillian M, Lee, Wai, Davis, Clare, Yaqoob, Mohammed, Phagoo, Steve B, Phillips, Elsa, Perkins, Martin N, Campbell, Elizabeth A, Davis, Andrew J and Rang, Humphrey P (2002) Nonpeptide bradykinin B2 receptor antagonists: conversion of rodent-selective bradyzide analogues into potent, orally-active human bradykinin B2 receptor antagonists. Journal of Medicinal Chemistry, 45 (11). pp. 2160-2172. ISSN 0022-2623

Dziadulewicz, Edward K, Ritchie, Timothy J, Hallett, Allan, Snell, Christopher R, Ko, Soo Y, Wrigglesworth, Roger, Hughes, Glyn A, Dunstan, Andrew R, Bloomfield, Graham C, Drake, Gillian S, Brown, Michael C, Lee, Wai, Burgess, Gillian M, Davis, Clare, Yaqoob, Mohammed, Perkins, Martin N, Campbell, Elizabeth A, Davis, Andrew J and Rang, Humphrey P (2000) 1-(2-Nitrophenyl)thiosemicarbazides: a novel class of potent, orally active non-peptide antagonist for the Bradykinin B2 receptor. Journal of Medicinal Chemistry, 43 (5). pp. 769-771. ISSN 0022-2623

Burgess, Gillian M, Perkins, Martin N, Rang, Humphrey P, Campbell, Elizabeth A, Brown, Michael C, McIntyre, Peter, Urban, Laszlo, Dziadulewicz, Edward K, Ritchie, Timothy J, Hallett, Allan, Snell, Christopher R, Wrigglesworth, Roger, Lee, Wai, Davis, Clare, Phagoo, Steve B, Davis, Andrew J, Phillips, Elsa, Drake, Gillian S, Hughes, Glyn A, Dunstan, Andrew and Bloomfield, Graham C (2000) Bradyzide, a potent non-peptide B2bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesia. British Journal of Pharmacology, 129 (1). pp. 77-86. ISSN 0007-1188

Walpole, Christopher S J, Bevan, Stuart, Bloomfield, Graham, Breckenridge, Robin, James, Iain F, Ritchie, Timothy, Szallasi, Arpad, Winter, Janet and Wrigglesworth, Roger (1996) Similarities and differences in the structure−activity relationships of capsaicin and resiniferatoxin analogues. Journal of Medicinal Chemistry, 39 (15). pp. 2939-2952. ISSN 0022-2623

Bloomfield, Graham C, Ritchie, Timothy J and Wrigglesworth, Roger (1992) Synthesis of 2,9,10-trioxatricyclo[]decane analogues of resiniferatoxin. Journal of the Chemical Society. Perkin Transactions 1 (10). pp. 1229-1236. ISSN 0300-922X

Bloomfield, Graham C, Wrigglesworth, Roger and Ritchie, Timothy J (1991) The stereoselective synthesis of 2,9,10 trioxatricyclo[]decane analogues of resiniferatoxin. Journal of the Chemical Society, Chemical Communications, 22 (4). pp. 215-217. ISSN 0022-4936

Conference or Workshop Item

Danahay, H, Coote, K, Paisley, D, Czarnecki, S, Atherton, H, Young, A, Gosling, M, Abraham, W, Sabater, J, Lock, R, Smith, N, Stanley, E, Butler, R, Bloomfield, G, Baettig, U, Cox, B and Collingwood, S P (2010) Novel dimeric amiloride derivatives: airway efficacy & reduced renal-based side effects. In: The 24th Annual North American Cystic Fibrosis Conference, October 21-23, 2010, Baltimore, Maryland, USA.


Novartis Ag (2014) Preparation of tricyclic compounds as CFTR channel inhibitors for treating polycystic kidney disease and diarrhea. WO2014097147A1.

Novartis Ag (2009) Preparation of cyclic guanidinocarbonylpyrazines as epithelial sodium channel (ENaC) blockers. WO2009074575 A3.

Novartis AG, Cox, B et al (2007) Preparation of pyrazolo[3,4-d]pyrimidine derivatives for treating respiratory disorders. WO2007134828.

Novartis Ag (2006) Pyrazole derivatives for treating conditions mediated by activation of the adenosine a2b or a3 receptor. WO 2006015860 A2.

Novartis Ag (2005) 5-phenyl-4-methyl-thiazol-2-yl-amine derivatives as inhibitors of phosphatidylinositol 3 kinase enzymes (pi3) for the treatment of inflammatory airway diseases. WO2005021519 A2.

Novartis Ag (2004) 5-phenylthiazole derivatives and their use as p13 kinase inhibitors. WO2004078754 A1.

Novartis Ag (2003) Derives du 5-phenylthiazol et leurs utilisations comme inhibiteurs de la pi3 kinase. WO 2003072557 A1.

This list was generated on Sat Jun 25 15:22:19 2022 BST.