Molecular mechanisms for thrombosis risk in black people: a role in excess mortality from COVID-19

Ramasamy, Roshan, Milne, Kate, Bell, Deanne, Stoneham, Simon and Chevassut, Timothy (2020) Molecular mechanisms for thrombosis risk in black people: a role in excess mortality from COVID-19. British Journal of Haematology. pp. 1-2. ISSN 0007-1048

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Abstract

We read with great interest your recent article by Fogarty et al,[1] in particular their conclusion that differences in thrombotic risk may contribute to ethnic differences in mortality from Covid-19. This is particularly important in the UK, where age- and sex-adjusted hospital death rates for Covid-19 are 2.17 higher for people with ethnicity recorded as black compared to white people, and 1.95 higher for those recorded as Asian.[3] This excess mortality is persists after adjustment for deprivation, body mass index (BMI), smoking and comorbidities,[3] and despite correction for region, rural/urban living, deprivation, household composition, socioeconomic status and health.[2] As yet uninvestigated factors such as thrombosis may contribute to the UK’s ethnic disparities in Covid-19. Similarly data from the USA shows that in 14 states, African-Americans represent 33% of hospitalisations for Covid-19, despite making up 14% of the catchment population.[4]

Item Type: Article
Schools and Departments: Brighton and Sussex Medical School > Clinical and Experimental Medicine
Subjects: R Medicine
R Medicine > RB Pathology
R Medicine > RB Pathology > RB127 Manifestations of disease
Depositing User: Timothy Chevassut
Date Deposited: 10 Jul 2020 10:16
Last Modified: 18 May 2021 14:30
URI: http://sro.sussex.ac.uk/id/eprint/92470

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