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‘Becoming-with’ a repeat healthy volunteer: managing and negotiating trust among repeat healthy volunteers in commercial clinical drug trials

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posted on 2023-06-09, 19:55 authored by Shadreck Mwale
Recent sociological research has raised important sociological and ethical questions about the role of financial rewards in terms of healthy volunteer involvement in clinical trials. Research suggests that it would be parochial to assume financial rewards alone are sufficient to explain repeat healthy volunteering. This paper explores other factors that might explain repeat healthy volunteering behaviours in phase I clinical drug trials. Drawing on qualitative research with healthy volunteers, the paper argues that while healthy volunteers make rational decisions to take part in drug trials, understanding how they become repeat volunteers requires considering varied relationships and networks involved. Drawing on Deleuze's concept of ‘event’ and ‘becoming-with’, the paper illustrates the relational, processual and embodied nature of trust in repeat healthy volunteer involvement in clinical drug trials. The paper concludes that repeat healthy volunteering is a constant flux of negotiating trust and mistrust. The paper contributes to sociological debates about trust and public engagement with technological innovations to illustrate trust among healthy volunteers as processual and changeable.

History

Publication status

  • Published

File Version

  • Published version

Journal

Social Science and Medicine

ISSN

0277-9536

Publisher

Elsevier

Volume

245

Article number

a112670

Department affiliated with

  • Clinical and Experimental Medicine Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2019-12-11

First Open Access (FOA) Date

2020-11-16

First Compliant Deposit (FCD) Date

2019-12-11

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