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Thalamo-cortical disconnection affects the somatic marker and social cognition - a case report.pdf (298.51 kB)

Thalamocortical disconnection affects the somatic marker and social cognition: a case report

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posted on 2023-06-09, 17:33 authored by Laura Serra, Michela Bruschini, Cristina Ottaviani, Carlotta Di Domenico, Lucia Fadda, Carlo Caltagirone, Mara Cercignani, Giovanni Augusto Carlesimo, Marco Bozzali
Thalamo-cortical connectivity was characterised in a patient with bilateral infarct of the thalami, without evidence of cognitive deficits in everyday life. Patient underwent social and emotional tests, Iowa Gambling Task (IGT), with and without concomitant heart rate variability (HRV) recording and at 3T-MRI to assess thalamo-cortical connectivity. Patient showed impairment at the IGT, in somatic marker, in emotions and theory of mind. MRI documented a bilateral damage of the centromedian-parafascicular complex. Patient's thalamic lesions disconnected brain areas involved in decision-making and autonomic regulation, affecting the somatic marker and resulting in the neuropsychological deficit exhibited by L.C.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Neurocase

ISSN

1465-3656

Publisher

Taylor & Francis

Department affiliated with

  • BSMS Neuroscience Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2019-04-10

First Open Access (FOA) Date

2020-03-18

First Compliant Deposit (FCD) Date

2019-04-10

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