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Enhancing cognition by affecting memory reconsolidation

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posted on 2023-06-09, 16:54 authored by Emiliano MerloEmiliano Merlo, Amy L Milton, Barry J Everitt
Fully consolidated associative memories can undergo a retrieval-dependent reconsolidation process, which allows for the updating and strengthening of the original association. Limiting, or so-called boundary, conditions determine whether a particular retrieval event triggers reconsolidation. Manipulating memories at reconsolidation may offer an opportunity to improve cognitive capacities in humans by increasing memory persistence, specificity and accuracy. Also, preventing the reconsolidation of maladaptive memories that characterize some neuropsychiatric disorders, such as post-traumatic stress disorder or drug addiction may offer a novel approach to treatment. Here we review recent advances in understanding and manipulating memory reconsolidation in both animals and humans, and discuss the potential of such interventions in cognitive enhancement.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Current Opinion in Behavioral Sciences

ISSN

2352-1546

Publisher

Elsevier

Volume

4

Page range

41-47

Department affiliated with

  • Psychology Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2019-02-18

First Open Access (FOA) Date

2019-02-18

First Compliant Deposit (FCD) Date

2019-02-15

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