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Regional brain atrophy and functional disconnection across Alzheimer's disease evolution

journal contribution
posted on 2023-06-07, 16:18 authored by T Gili, Mara Cercignani, L Serra, R Perri, F Giove, B Maraviglia, C Caltagirone, M Bozzali
This study indicates that disconnection precedes GM atrophy in the PCC, which is a critical area of the DMN, and supports the hypothesis that GM atrophy in specific regions of AD brains likely reflects a long term effect of brain disconnection. In this context, our study indicates that GM atrophy in PCC accompanies the conversion from MCI to AD.

History

Publication status

  • Published

Journal

Journal of Neurology, Neurosurgery and Psychiatry

ISSN

0022-3050

Publisher

BMJ Publishing Group

Issue

1

Volume

82

Page range

58-66

Department affiliated with

  • Clinical and Experimental Medicine Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2012-04-24

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