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Tumor–stromal cell communication: small vesicles signal big changes

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posted on 2023-06-09, 08:59 authored by Franz Wendler, Gordon Stamp, Georgios GiamasGeorgios Giamas
Reciprocal interactions between malignant and stromal cells create a local microenvironment that fosters tumor growth. Extracellular vesicles (EVs) such as exosomes, microvesicles, and large oncosomes are involved in tumor–stroma communication by shuttling signaling cargo and other molecules. Here we discuss how EVs released by cancer or stromal cells impact the proliferation, differentiation, and metabolism of tumors.

History

Publication status

  • Published

File Version

  • Accepted version

Journal

Trends in Cancer

ISSN

2405-8033

Publisher

CellPress

Issue

7

Volume

2

Page range

326-329

Department affiliated with

  • Biochemistry Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2017-11-23

First Open Access (FOA) Date

2017-11-23

First Compliant Deposit (FCD) Date

2017-11-23

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