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SPIE Conference Paper wk2 Jan 9 2017 v3.pdf (961.49 kB)

Current source enhancements in Electrical Impedance Spectroscopy (EIS) to cancel unwanted capacitive effects

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conference contribution
posted on 2023-06-09, 05:47 authored by Ali Zarafshani, Thomas Bach, Chris ChatwinChris Chatwin, Liangzhong Xiang, Bin Zheng
Electrical Impedance Spectroscopy (EIS) has emerged as a non-invasive imaging modality to detect and quantify functional or electrical properties related to the suspicious tumors in cancer screening, diagnosis and prognosis assessment. A constraint on EIS systems is that the current excitation system suffers from the effects of stray capacitance having a major impact on the hardware subsystem as the EIS is an ill-posed inverse problem which depends on the noise level in EIS measured data and regularization parameter in the reconstruction algorithm. There is high complexity in the design of stable current sources, with stray capacitance reducing the output impedance and bandwidth of the system. To confront this, we have designed an EIS current source which eliminates the effect of stray capacitance and other impacts of the capacitance via a variable inductance. In this paper, we present a combination of operational CCII based on a generalized impedance converter (OCCII-GIC) with a current source. The aim of this study is to use the EIS system as a biomedical imaging technique, which is effective in the early detection of breast cancer. This article begins with the theoretical description of the EIS structure, current source topologies and proposes a current conveyor in application of a Gyrator to eliminate the current source limitations and its development followed by simulation and experimental results. We demonstrated that the new design could achieve a high output impedance over a 3MHz frequency bandwidth when compared to other types of GIC circuits combined with an improved Howland topology.

History

Publication status

  • Published

File Version

  • Published version

Journal

Proceedings of SPIE, Medical Imaging 2017: Biomedical Applications in Molecular, Structural, and Functional Imaging

ISSN

1605-7422

Publisher

SPIE

Volume

10137

Page range

101371X

Event name

Medical Imaging 2017: Biomedical Applications in Molecular, Structural, and Functional Imaging

Event location

Orlando, Florida, United States

Event type

conference

Event date

February 11-16, 2017

Place of publication

SPIE USA

Department affiliated with

  • Engineering and Design Publications

Research groups affiliated with

  • Industrial Informatics and Signal Processing Research Group Publications

Notes

Copyright SPIE Proceedings (2017) Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2017-04-12

First Open Access (FOA) Date

2017-04-12

First Compliant Deposit (FCD) Date

2017-04-12

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