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Factors influencing feeding elicited by intracranial noradrenaline in rats
journal contribution
posted on 2023-06-08, 22:16 authored by J W Matthews, D A Booth, I P StolermanAn improved design of microcannula was used to inject noradrenaline into discrete areas of the rat hypothalamus. The area of the paraventricular nucleus was shown to be a more effective site than the midlateral anterior hypothalamus for eliciting feeding with noradrenaline (4.8 µg). The magnitude but not the direction of the effect of noradrenaline on feeding was influenced by the day-night cycle. The facilitating effect of the drug reached significance in the light period but not in the dark period, possibly because the baseline food intake was higher by night than by day. The facilitation of feeding occurred whether the rats were maintained and tested on a diet of solid or liquid food.
History
Publication status
- Published
Journal
Brain ResearchISSN
0006-8993Publisher
ElsevierExternal DOI
Issue
1Volume
141Page range
119-128Department affiliated with
- Psychology Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2015-08-28Usage metrics
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