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Factors influencing feeding elicited by intracranial noradrenaline in rats

journal contribution
posted on 2023-06-08, 22:16 authored by J W Matthews, D A Booth, I P Stolerman
An improved design of microcannula was used to inject noradrenaline into discrete areas of the rat hypothalamus. The area of the paraventricular nucleus was shown to be a more effective site than the midlateral anterior hypothalamus for eliciting feeding with noradrenaline (4.8 µg). The magnitude but not the direction of the effect of noradrenaline on feeding was influenced by the day-night cycle. The facilitating effect of the drug reached significance in the light period but not in the dark period, possibly because the baseline food intake was higher by night than by day. The facilitation of feeding occurred whether the rats were maintained and tested on a diet of solid or liquid food.

History

Publication status

  • Published

Journal

Brain Research

ISSN

0006-8993

Publisher

Elsevier

Issue

1

Volume

141

Page range

119-128

Department affiliated with

  • Psychology Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-08-28

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