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Synthesis and epimerisation studies on carbohydrate derived bicyclic tetronate esters: the synthesis of furanofurans related to the cytotoxic metabolite goniofufurone

journal contribution
posted on 2023-06-08, 19:31 authored by Cristiano Cagnolini, Marina Ferri, Peter R Jones, Patrick J Murphy, Barry Ayres, Brian Cox
The synthesis of the D-xylo- 12, D-lyxo- 13, D-ribo- 14 and D-arabino-furanofurans15 was accomplished from the readily available butyrolactones 4 and 5via a non-classical Wittig cyclisation/hydrogenation sequence; these compounds are analogues of the cytotoxic natural product goniofufurone.

History

Publication status

  • Published

Journal

Tetrahedron

ISSN

0040-4020

Publisher

Elsevier

Issue

13

Volume

53

Page range

4815-4820

Department affiliated with

  • Chemistry Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2015-01-13

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