University of Sussex
Browse

File(s) not publicly available

To live or to die: a matter of processing damaged DNA termini in neurons

journal contribution
posted on 2023-06-07, 21:48 authored by Sherif El-Khamisy
Defects in the repair of deoxyribonucleic acid (DNA) damage underpin several hereditary neurological diseases in humans. Of the different activities that repair chromosomal DNA breaks, defects in resolving damaged DNA termini are among the most common causes of neuronal cell death. Here, the molecular mechanisms of some of the DNA end processing activities are reviewed and the association with human neurodegenerative disease is discussed.

History

Publication status

  • Published

Journal

EMBO Molecular Medicine

ISSN

17574676

Publisher

Wiley-Blackwell

Issue

2

Volume

3

Page range

78-88

Pages

78.0

Series

EMBO Mol Med

Department affiliated with

  • Sussex Centre for Genome Damage Stability Publications

Full text available

  • No

Peer reviewed?

  • No

Legacy Posted Date

2012-02-06

Usage metrics

    University of Sussex (Publications)

    Categories

    No categories selected

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC