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Number of items at this level: 23.

B

Barroca-Aubry, Nadine, Benchekroun, Mohamed, Gomes, Filipe and Bonnaffé, David (2013) p-Methoxybenzyl-N-phenyl-2,2,2-trifluoroacetimidate: a versatile reagent for mild acid catalyzed etherification. Tetrahedron Letters, 54 (37). pp. 5118-5121. ISSN 0040-4039

Benchekroun, Mohamed, Bartolini, Manuela, Egea, Javier, Romero, Alejandro, Soriano, Elena, Pudlo, Marc, Luzet, Vincent, Andrisano, Vincenza, Jimeno, María-Luisa, López, Manuela G, Wehle, Sarah, Gharbi, Tijani, Refouvelet, Bernard, de Andrés, Lucía, Herrera-Arozamena, Clara, Monti, Barbara, Bolognesi, Maria Laura, Rodríguez-Franco, María Isabel, Decker, Michael, Marco-Contelles, José and Ismaili, Lhassane (2015) Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids. ChemMedChem, 10 (3). pp. 523-539. ISSN 18607179

Benchekroun, Mohamed, Ismaili, Lhassane, Pudlo, Marc, Luzet, Vincent, Gharbi, Tijani, Refouvelet, Bernard and Marco-Contelles, José (2015) Donepezil–ferulic acid hybrids as anti-Alzheimer drugs. Future Medicinal Chemistry, 7 (1). pp. 15-21. ISSN 1756-8919

Benchekroun, Mohamed, Romero, Alejandro, Egea, Javier, León, Rafael, Michalska, Patrycja, Buendía, Izaskun, Jimeno, María Luisa, Jun, Daniel, Janockova, Jana, Sepsova, Vendula, Soukup, Ondrej, Bautista-Aguilera, Oscar M, Refouvelet, Bernard, Ouari, Olivier, Marco-Contelles, José and Ismaili, Lhassane (2016) The antioxidant additive approach for Alzheimer’s disease therapy: new ferulic (lipoic) acid plus melatonin modified tacrines as cholinesterases inhibitors, direct antioxidants, and nuclear factor (erythroid-derived 2)-like 2 activators. Journal of Medicinal Chemistry, 59 (21). pp. 9967-9973. ISSN 0022-2623

Benson, Matthew, Tinsley, Caroline, Waite, Aidan, Carlisle, Francesca, Sweet, Steve, Ehler, Elisabeth, George, Christopher, Lai, Anthony, Martin-Rendon, Enca and Blake, Derek (2017) Ryanodine receptors are part of the myospryn complex in cardiac muscle. Scientific Reports, 7 (6312). pp. 1-12. ISSN 2045-2322

C

Coote, K J, Paisley, D, Czarnecki, S, Tweed, M, Watson, H, Young, A, Sugar, R, Vyas, M, Smith, N J, Baettig, U, Groot-Kormelink, P J, Gosling, M, Lock, R, Ethell, B, Williams, G, Schumacher, A, Harris, J, Abraham, W M, Sabater, J, Poll, C T, Faller, T, Collingwood, S P and Danahay, H (2015) NVP-QBE170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia. British Journal of Pharmacology, 172 (11). pp. 2814-2826. ISSN 0007-1188

D

Derudas, Marco, Vanpouille, Christophe, Carta, Davide, Zicari, Sonia, Andrei, Graciela, Snoeck, Robert, Brancale, Andrea, Margolis, Leonid, Balzarini, Jan and McGuigan, Christopher (2017) Virtual Screening of acyclovir derivatives as potential antiviral agents: design, synthesis, and biological evaluation of new acyclic nucleoside ProTides. Journal of Medicinal Chemistry. ISSN 0022-2623

Dgachi, Youssef, Bautista-Aguilera, Oscar, Benchekroun, Mohamed, Martin, Hélène, Bonet, Alexandre, Knez, Damijan, Godyń, Justyna, Malawska, Barbara, Gobec, Stanislav, Chioua, Mourad, Janockova, Jana, Soukup, Ondrej, Chabchoub, Fakher, Marco-Contelles, José and Ismaili, Lhassane (2016) Synthesis and biological evaluation of benzochromenopyrimidinones as cholinesterase inhibitors and potent antioxidant, non-hepatotoxic agents for Alzheimer’s disease. Molecules, 21 (5). p. 634. ISSN 1420-3049

Dgachi, Youssef, Ismaili, Lhassane, Knez, Damijan, Benchekroun, Mohamed, Martin, Hélène, Szałaj, Natalia, Wehle, Sarah, Bautista-Aguilera, Oscar M, Luzet, Vincent, Bonnet, Alexandre, Malawska, Barbara, Gobec, Stanislav, Chioua, Mourad, Decker, Michael, Chabchoub, Fakher and Marco-Contelles, José (2016) Synthesis and biological assessment of racemic benzochromenopyrimidinimines as antioxidant, cholinesterase, and Aβ1−42 aggregation inhibitors for Alzheimer's disease therapy. ChemMedChem, 11 (12). pp. 1318-1327. ISSN 1860-7179

I

Ismaili, Lhassane, Refouvelet, Bernard, Benchekroun, Mohamed, Brogi, Simone, Brindisi, Margherita, Gemma, Sandra, Campiani, Giuseppe, Filipic, Slavica, Agbaba, Danica, Esteban, Gerard, Unzeta, Mercedes, Nikolic, Katarina, Butini, Stefania and Marco-Contelles, José (2017) Multitarget compounds bearing tacrine- and donepezil-like structural and functional motifs for the potential treatment of Alzheimer's disease. Progress in Neurobiology, 151. pp. 4-34. ISSN 0301-0082

K

Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Siân R, O'Reilly, Molly, Derudas, Marco, Cantillon, Daire M, Goodyear, Richard J, Secker, Abigail, Baxendale, Sarah, Bulley, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corné J and Richardson, Guy P (2017) Identification of ion-channel modulators that protect against aminoglycoside-induced hair-cell death. Journal of Clinical Investigation Insight, 2 (24). ISSN 2379-3708

Kirkwood, Nerissa K, O'Reilly, Molly, Derudas, Marco, Kenyon, Emma J, Huckvale, Rosemary, van Netten, Sietse M, Ward, Simon E, Richardson, Guy P and Kros, Corné Kros (2017) d-Tubocurarine and berbamine: alkaloids that are permeant blockers of the hair cell's mechano-electrical transducer channel and protect from aminoglycoside toxicity. Frontiers in Cellular Neuroscience, 11. ISSN 1662-5102

Kraft, L, Roe, M, Gill, R and Atack, J R (2018) Co‐crystallization of human inositol monophosphatase with the lithium mimetic L‐690,330. Acta Crystallographica Section D: Structural Biology, 74. pp. 973-978. ISSN 0907-4449

M

Miller, Andrew T, Dahlberg, Carol, Sandberg, Mark L, Wen, Ben G, Beisner, Daniel R, Hoerter, John A H, Parker, Albert, Schmedt, Christian, Stinson, Monique, Avis, Jacqueline, Cienfuegos, Cynthia, McPate, Mark, Tranter, Pamela, Gosling, Martin, Groot-Kormelink, Paul J, Dawson, Janet, Pan, Shifeng, Tian, Shin-Shay, Seidel, H Martin and Cooke, Michael P (2015) Inhibition of the inositol kinase Itpkb augments calcium signaling in lymphocytes and reveals a novel strategy to treat autoimmune disease. PLoS ONE, 10 (6). e0131071. ISSN 1932-6203

Mok, Myth T, Zhou, Jingying, Tang, Wenshu, Zeng, Xuezhen, Oliver, Antony W, Ward, Simon E and Cheng, Alfred S L (2018) CCRK is a novel signalling hub exploitable in cancer immunotherapy. Pharmacology and Therapeutics. ISSN 0163-7258

N

Naret, Timothée, Bignon, Jérôme, Bernadat, Guillaume, Benchekroun, Mohamed, Levaique, Helene, Lenoir, Christine, Dubois, Joelle, Pruvost, Alain, Saller, François, Borgel, Delphine, Manoury, Boris, Leblais, Veronique, Darrigrand, Romain, Apcher, Sébastien, Brion, Jean-Daniel, Schmitt, Etienne, Leroux, Frédéric R, Alami, Mouad and Hamze, Abdallah (2018) A fluorine scan of a tubulin polymerization inhibitor isocombretastatin A-4: Design, synthesis, molecular modelling, and biological evaluation. European Journal of Medicinal Chemistry, 143. pp. 473-490. ISSN 0223-5234

Noble, James William, Almalki, Rehab, Roe, Mark, Duman, Ramona, Wagner, Armin and Atack, John (2018) The X-ray structure of human calbindin-D28K: an improved model. Acta Crystallographica Section D: Structural Biology, 74 (10). pp. 1008-1014. ISSN 2059-7983

O

O'Reilly, Molly, Kirkwood, Nerissa K, Kenyon, Emma J, Huckvale, Rosemary, Cantillon, Daire M, Waddell, Simon J, Ward, Simon E, Richardson, Guy P, Kros, Corne J and Derudas, Marco (2019) Design, synthesis and biological evaluation of a new series of carvedilol derivatives that protect sensory hair cells from aminoglycoside-induced damage by blocking the mechano-electrical transducer channel. Journal of Medicinal Chemistry. ISSN 0022-2623

R

Reuillon, Tristan, Ward, Simon and Beswick, Paul (2016) AMPA receptor positive allosteric modulators: potential for the treatment of neuropsychiatric and neurological disorders. Current Topics in Medicinal Chemistry, 16 (29). pp. 3536-3565. ISSN 1568-0266

Romero, Eugénie, Minard, Corinne, Benchekroun, Mohamed, Ventre, Sandrine, Retailleau, Pascal, Dodd, Robert H and Cariou, Kevin (2017) Base-mediated generation of ketenimines from ynamides: direct access to azetidinimines by an imino staudinger synthesis. Chemistry - A European Journal, 23 (53). pp. 12991-12994. ISSN 0947-6539

T

Tomassoli, Isabelle, Herlem, Guillaume, Picaud, Fabien, Benchekroun, Mohamed, Bautista-Aguilera, Oscar M, Luzet, Vincent, Jimeno, María-Luisa, Gharbi, Tijani, Refouvelet, Bernard and Ismaili, Lhassane (2016) Synthesis, regioselectivity, and DFT analysis of new antioxidant pyrazolo[4,3-c]quinoline-3,4-diones. Chemical Monthly / Monatshefte für Chemie, 147 (6). pp. 1069-1079. ISSN 0026-9247

W

West, Ryan, Cunningham, Thomas, Pennicott, Lewis, Rao, Srinivasa and Ward, Simon (2018) Toward more drug like inhibitors of trypanosome alternative oxidase. ACS Infectious Diseases. ISSN 2373-8227

West, Ryan A, O'Doherty, Oran G, Askwith, Trevor, Atack, John, Beswick, Paul, Laverick, Jamie, Paradowski, Michael, Pennicott, Lewis E, Rao, Srinivasa P S, Williams, Gareth and Ward, Simon E (2017) African trypanosomiasis: Synthesis & SAR enabling novel drug discovery of ubiquinol mimics for trypanosome alternative oxidase. European Journal of Medicinal Chemistry, 141. pp. 676-689. ISSN 0223-5234

This list was generated on Wed Jul 17 08:58:10 2019 BST.