A

Agnarelli, Alessandro, Chevassut, Timothy and Mancini, Erika (2018) IRF4 in multiple myeloma—biology, disease and therapeutic target. Leukemia Research, 72. pp. 52-58. ISSN 0145-2126

Almohammed, Rajaei, Osborn, Kay, Ramasubramanyan, Sharada, Naranjo Perez-Fernandez, Ijiel Barak, Godfrey, Anja, Mancini, Erika J and Sinclair, Alison J (2018) Mechanism of activation of the BNLF2a immune evasion gene of Epstein-Barr virus by Zta. Journal of General Virology, 99. pp. 805-817. ISSN 0022-1317

B

Bark-Jones, S J, Webb, H M and West, M J (2006) EBV EBNA 2 stimulates CDK9-dependent transcription and RNA polymerase II phosphorylation on serine 5. Oncogene, 25 (12). pp. 1775-1785. ISSN 0950-9232

Binks, Sophie, Regan, Kate, Richenberg, Jonathan and Chevassut, Tim (2012) Microbes without frontiers: severe haemolytic-uraemic syndrome due to E coli O104:H4. BMJ Case Reports, 2012. ISSN 1757-790X

Bisling, Kathrin E, Brewin, John N, McGovern, Andrew P, Horne, Gillian A, Rider, Tom, Stewart, Helen J, Ramsahoye, Bernard H and Chevassut, Timothy J (2014) DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia. Leukemia & Lymphoma, 55 (3). pp. 711-714. ISSN 1029-2403

Brewin, John, Horne, Gillian and Chevassut, Timothy (2013) Genomic landscapes and clonality of de novo AML. New England Journal of Medicine, 369 (15). pp. 1472-1473. ISSN 0028-4793

Brewin, John N, Horne, Gillian A, Bisling, Kathrin E, Stewart, Helen J and Chevassut, Timothy J (2013) Rapid detection of DNMT3A R882 codon mutations allows early identification of poor risk patients with acute myeloid leukemia. Leukemia & Lymphoma, 54 (6). pp. 1336-1339. ISSN 1042-8194

Brocard, Michèle, Khasnis, Sarika, Wood, C David, Shannon-Lowe, Claire and West, Michelle J (2018) Pumilio directs deadenylation-associated translational repression of the cyclin-dependent kinase 1 activator RGC-32. Nucleic Acids Research, 46 (7). pp. 3707-3725. ISSN 0305-1048

Bulian, Pietro, Shanafelt, Tait D, Fegan, Chris, Zucchetto, Antonella, Cro, Lilla, Nückel, Holger, Baldini, Luca, Kurtova, Antonina V, Ferrajoli, Alessandra, Burger, Jan A., Gaidano, Gianluca, Del Poeta, Giovanni, Pepper, Chris, Rossi, Davide and Gattei, Valter (2014) CD49d Is the strongest flow cytometry–based predictor of overall survival in chronic lymphocytic leukemia. Journal of Clinical Oncology, 32 (9). pp. 897-904. ISSN 0732-183X

C

Chaudry, Sabah and Chevassut, Timothy (2017) Epigenetic guardian: a review of the DNA methyltransferase DNMT3A in acute myeloid leukaemia and clonal haematopoiesis. Biomed Research International, 2017. p. 5473197. ISSN 2314-6133

Chevassut, Timothy, Bart-Smith, Emily and Shah, Gulnaz (2015) [Correspondence] Somatic mutations and clonal hematopoiesis in aplastic anemia. New England Journal of Medicine, 373 (17). pp. 1673-1674. ISSN 0028-4793

Chevassut, Timothy, Chowdhury, Basudev, McGovern, Andrew, Cui, Yi, Choudhury, Samrat Roy, Cho, Il-Hoon, Cooper, Bruce, Lossie, Amy C and Irudayaraj, Joseph (2015) The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells. Scientific Reports, 5. p. 9281. ISSN 1992-2248

Chevassut, Timothy, Gabriel, Joseph, McGovern, Andrew, Robinson, Stephen and Wright, David (2016) [Correspondence] A systematic study comparing aspirate versus trephine for quantifying plasma cell infiltration in newly-diagnosed myeloma. British Journal of Haematology, 174 (5). pp. 818-819. ISSN 0007-1048

Chevassut, Timothy, Rider, Tom and Malik, Muzaffar (2014) Haematology patients and the Internet: the use of on-line health information and the impact on the patient-doctor relationship. Patient Education and Counselling, 97 (2). pp. 223-238. ISSN 0738-3991

Conway O'Brien, Emma, Brewin, John and Chevassut, Timothy (2014) DNMT3A: the DioNysian MonsTer of acute myeloid leukaemia. Therapeutic Advances in Hematology, 5 (6). pp. 187-196. ISSN 2040-6207

Corcoran, David B, Lewis, Thomas, Nahar, Kazi S, Jamshidi, Shirin, Fegan, Christopher, Pepper, Chris, Thurston, David E and Rahman, Khondaker Miraz (2019) Effects of systematic shortening of noncovalent C8 side chain on the cytotoxicity and NF-κB inhibitory capacity of pyrrolobenzodiazepines (PBDs). Journal of Medicinal Chemistry, 62 (4). pp. 2127-2139. ISSN 0022-2623

Coulter, Eve M, Pepper, Andrea, Mele, Silvia, Folarin, Najeem'deen, Townsend, William, Cuthill, Kirsty, Phillips, Elizabeth, Patten, Piers and Devereux, Stephen (2018) In-vitro and in-vivo evidence for uncoupling of BCR internalization and signaling in chronic lymphocytic leukemia. Haematologica, 103 (3). pp. 497-505. ISSN 1592-8721

D

Dempke, WC M, Uciechowski, P, Fenchel, K and Chevassut, T (2018) Targeting SHP-1,2 and SHIP pathways – a novel strategy for cancer treatment? Oncology, 95 (5). pp. 257-269. ISSN 0030-2414

Dempke, Wolfram C M, Fenchel, Klaus, Uciechowski, Peter and Chevassut, Timothy (2017) Targeting developmental pathways: the Achilles Heel of cancer? Oncology, 93 (4). pp. 213-223. ISSN 0030-2414

E

El Omari, Kamel, Hoosdally, Sarah J, Tuladhar, Kapil, Karia, Dimple, Hall-Ponselé, Elisa, Platonova, Olga, Vyas, Paresh, Patient, Roger, Porcher, Catherine and Mancini, Erika J (2013) Structural basis for LMO2-driven recruitment of the SCL: E47bHLH heterodimer to hematopoietic-specific transcriptional targets. Cell Reports, 4 (1). pp. 135-147. ISSN 2211-1247

El Omari, Kamel, Hoosdally, Sarah J, Tuladhar, Kapil, Karia, Dimple, Vyas, Paresh, Patient, Roger, Porcher, Catherine and Mancini, Erika J (2011) Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex. Blood, 117 (7). pp. 2146-2156. ISSN 1528-0020

Escudero, Laura, Cleal, Kez, Ashelford, Kevin, Fegan, Chris, Pepper, Chris, Liddiard, Kate and Baird, Duncan M (2019) [Letter to the editor] Telomere fusions associate with coding sequence and copy number alterations in CLL. Leukemia. ISSN 0887-6924

F

Ferla, Salvatore, Aboraia, Ahmed S, Brancale, Andrea, Pepper, Christopher J, Zhu, Jinge, Ochalek, Justin T, DeLuca, Hector F and Simons, Claire (2014) Small-molecule inhibitors of 25-hydroxyvitamin D-24-hydroxylase (CYP24A1): synthesis and biological evaluation. Journal of Medicinal Chemistry, 57 (18). pp. 7702-7715. ISSN 0022-2623

G

Ghurye, Rohit R, Stewart, Helen J S and Chevassut, Timothy (2015) Bromodomain inhibition by JQ1 suppresses lipopolysaccharide-stimulated interleukin-6 secretion in multiple myeloma cells. Cytokine, 71 (2). pp. 415-417. ISSN 1043-4666

Gounaris-Shannon, Stephanie and Chevassut, Timothy (2013) The role of miRNA in haematological malignancy. Bone Marrow Research, 2013 (269107). pp. 1-12. ISSN 2090-2999

Gounaris-Shannon, Stephanie, Newbury, Sarah and Chevassut, Timothy (2013) MicroRNAs – key players in haematopoiesis. Current Signal Transduction Therapy, 8 (1). pp. 91-98. ISSN 1574-3624

Graham, Charlotte, Jozwik, Agnieszka, Pepper, Andrea and Benjamin, Reuben (2018) Allogeneic CAR-T cells: more than ease of access? Cells, 7 (10). p. 155. ISSN 2073-4409

Gross, Henrik, Barth, Stephanie, Palermo, Richard D, Mamiani, Alfredo, Hennard, Christine, Zimber-Strobl, Ursula, West, Michelle J, Kremmer, Elisabeth and Grasser, Friedrich A (2010) Asymmetric Arginine dimethylation of Epstein–Barr virus nuclear antigen 2 promotes DNA targeting. Virology, 397 (2). pp. 299-310. ISSN 0042-6822

Gunnell, Andrea, Webb, Helen M, Wood, C David, McClellan, Michael J, Wichaidit, Billy, Kempkes, Bettina, Jenner, Richard G, Osborne, Cameron, Farrell, Paul J and West, Michelle J (2016) RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth. Nucleic Acids Research, 44 (10). pp. 4636-4650. ISSN 0305-1048

H

Horne, Gillian, Brewin, John and Chevassut, Timothy (2012) Genetic profiling in acute myeloid leukemia. New England Journal of Medicine, 366 (24). pp. 2321-2322. ISSN 0028-4793

Horne, Gillian, Stewart, Helen J S, Dickson, Jacqueline, Knapp, Stefan, Ramsahoye, Bernard and Chevassut, Timothy (2015) Nanog requires BRD4 to maintain murine embryonic stem cell pluripotency and is suppressed by bromodomain inhibitor JQ1 together with lefty1. Stem Cells and Development, 24 (7). pp. 879-891. ISSN 1547-3287

Horne, Gillian A and Chevassut, Timothy (2012) Pregnancy in Shwachman-Diamond syndrome: a novel genetic mutation with minimal consequence. BMJ Case Reports, 2012. ISSN 1757-790X

Horne, Gillian A, Chevassut, Timothy J T, Fidler, Katy and Wynne, Catherine (2015) Haemolytic anaemia: don’t leave it out in the cold. Archives of Disease in Childhood. Education and Practice Edition, 100 (6). pp. 323-330. ISSN 1743-0585

Horne, Gillian Abigail, Bastow, Sarah, Stewart, Helen Jayne Susan and Chevassut, Timothy James Telfer (2013) BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1. Cancer Medicine, 2 (6). pp. 826-835. ISSN 2045-7634

Hyatt, Sam, Jones, Rhiannon E, Heppel, Nicole H, Grimstead, Julia W, Fegan, Chris, Jackson, Graham H, Hills, Robert, Allan, James M, Pratt, Guy, Pepper, Christopher and Baird, Duncan M (2017) Telomere length is a critical determinant for survival in multiple myeloma. British Journal of Haematology, 178 (1). pp. 94-98. ISSN 0007-1048

J

Jones, C I, Zabolotskaya, M V, King, A J, Stewart, H J S, Horne, G A, Chevassut, T J and Newbury, S F (2012) Identification of circulating microRNAs as diagnostic biomarkers for use in multiple myeloma. British Journal of Cancer, 107 (12). pp. 1987-1996. ISSN 0007-0920

K

Karia, Dimple, Gilbert, Robert C G, Biasutto, Antonio J, Porcher, Catherine and Mancini, Erika J (2020) The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain. Royal Society Open Science, 7 (1). ISSN 2054-5703

Knapper, Steven, Chevassut, Timothy, Duarte, Rafael, Bergua, Juan Miguel, Salamero, Olga, Johansen, Malin, Jacobsen, Tove Flem, Hals, Petter-Arnt, Rasch, Wenche, Gianella-Borradorif, Athos and Smith, Matthew (2014) Elacytarabine in relapsed/refractory acute myeloid leukaemia: an evaluation of clinical efficacy, pharmacokinetics, cardiac safety and effects on lipid profile. Leukemia Research, 38 (3). pp. 346-351. ISSN 0145-2126

L

Lam, Frankie, Abbas, Abdullahi Y, Shao, Hao, Teo, Theodosia, Adams, Julian, Li, Peng, Bradshaw, Tracey D, Fischer, Peter M, Walsby, Elisabeth, Pepper, Chris, Chen, Yi, Ding, Jian and Wang, Shudong (2014) Targeting RNA transcription and translation in ovarian cancer cells with pharmacological inhibitor CDKI-73. Oncotarget, 5 (17). pp. 7691-7704. ISSN 1949-2553

Law, Philip J, Berndt, Sonja I, Speedy, Helen E, Camp, Nicola J, Sava, Georgina P, Skibola, Christine F, Holroyd, Amy, Joseph, Vijai, Sunter, Nicola J, Nieters, Alexandra, Bea, Silvia, Monnereau, Alain, Martin-Garcia, David, Goldin, Lynn R, Clot, Guillem, Teras, Lauren R, Quintela, Inés, Birmann, Brenda M, Jayne, Sandrine, Cozen, Wendy, Majid, Aneela, Smedby, Karin E, Lan, Qing, Dearden, Claire, Brooks-Wilson, Angela R., Hall, Andrew G, Purdue, Mark P, Mainou-Fowler, Tryfonia, Vajdic, Claire M, Jackson, Graham H, Cocco, Pierluigi, Marr, Helen, Zhang, Yawei, Zheng, Tongzhang, Giles, Graham G, Lawrence, Charles, Call, Timothy G, Liebow, Mark, Melbye, Mads, Glimelius, Bengt, Mansouri, Larry, Glenn, Martha, Curtin, Karen, Diver, W Ryan, Link, Brian K, Conde, Lucia, Bracci, Paige M., Holly, Elizabeth A, Jackson, Rebecca D, Tinker, Lesley F, Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Maynadie, Marc, McKay, James, Albanes, Demetrius, Weinstein, Stephanie, Wang, Zhaoming, Caporaso, Neil E., Morton, Lindsay M, Severson, Richard K, Riboli, Elio, Vineis, Paolo, Vermeulen, Roel C H, Southey, Melissa C, Milne, Roger L., Clavel, Jacqueline, Topka, Sabine, Spinelli, John J, Kraft, Peter, Ennas, Maria Grazia, Summerfield, Geoffrey, Ferri, Giovanni M, Harris, Robert J, Miligi, Lucia, Pettitt, Andrew R, North, Kari E, Allsup, David J, Fraumeni, Joseph F, Bailey, James R, Offit, Kenneth, Pratt, Guy, Hjalgrim, Henrik, Pepper, Christopher, Chanock, Stephen J, Fegan, Chris, Rosenquist, Richard, de Sanjose, Silvia, Carracedo, Angel, Dyer, Martin J S, Catovsky, Daniel, Campo, Elias, Cerhan, James R., Allan, James M, Rothman, Nathanial, Houlston, Richard and Slager, Susan (2017) Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia. Nature Communications, 8. pp. 1-12. ISSN 2041-1723

Law, Philip J, Sud, Amit, Mitchell, Jonathan S, Henrion, Marc, Orlando, Giulia, Lenive, Oleg, Broderick, Peter, Speedy, Helen E, Johnson, David C, Kaiser, Martin, Weinhold, Niels, Cooke, Rosie, Sunter, Nicola J, Jackson, Graham H, Summerfield, Geoffrey, Harris, Robert J, Pettitt, Andrew R, Allsup, David J, Carmichael, Jonathan, Bailey, James R, Pratt, Guy, Rahman, Thahira, Pepper, Christopher, Fegan, Chris, von Strandmann, Elke Pogge, Engert, Andreas, Försti, Asta, Chen, Bowang, da Silva Filho, Miguel Inacio, Thomsen, Hauke, Hoffmann, Per, Noethen, Markus M, Eisele, Lewin, Jöckel, Karl-Heinz, Allan, James M, Swerdlow, Anthony J, Goldschmidt, Hartmut, Catovsky, Daniel, Morgan, Gareth J, Hemminki, Kari and Houlston, Richard S (2017) Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. Scientific Reports, 7. p. 41071. ISSN 2045-2322

M

Mancini, Erika J and West, Michelle J (2015) How to be a pioneer: a one-sided view. Trends in Biochemical Sciences, 40 (10). pp. 547-548. ISSN 0968-0004

McClellan, Michael J, Khasnis, Sarika, Wood, C David, Palermo, Richard D, Schlick, Sandra N, Kanhere, Aditi S, Jenner, Richard G and West, Michelle J (2012) Downregulation of Integrin Receptor-Signaling Genes by Epstein-Barr Virus EBNA 3C via Promoter-Proximal and -Distal Binding Elements. Journal of Virology, 86 (9). pp. 5165-5178. ISSN 0022-538X

McClellan, Michael J, Wood, C David, Ojeniyi, Opeoluwa, Cooper, Tim J, Kanhere, Aditi, Arvey, Aaron, Webb, Helen M, Palermo, Richard D, Harth-Hertle, Marie L, Kempkes, Bettina, Jenner, Richard G and West, Michelle (2013) Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming. PLoS Pathogens, 9 (9). e1003636. ISSN 1553-7366

McGovern, Andrew P, Powell, Benjamin E and Chevassut, Timothy J T (2012) A dynamic multi-compartmental model of DNA methylation with demonstrable predictive value in hematological malignancies. Journal of Theoretical Biology, 310 (7). pp. 14-20. ISSN 1095-8541

Mele, Sylvia, Devereux, Stephen, Pepper, Andrea G, Infante, Elvira and Ridley, Anne J (2018) Calcium-RasGRP2-Rap1 signaling mediates CD38-induced migration of chronic lymphocytic leukemia cells. Blood Advances, 2 (13). pp. 1551-1561. ISSN 2473-9529

Menendez-Gonzalez, Juan Bautista, Sinnadurai, Samantha, Gibbs, Alex, Thomas, Leigh-anne, Konstantinou, Maria, Garcia-Valverde, Alfonso, Boyer, Magali, Wang, Zhengke, Boyd, Ashleigh S, Blair, Allison, Morgan, Rhys G and Rodrigues, Neil P (2019) Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells. Scientific Reports, 9 (1). a12212. ISSN 2045-2322

Milton-Harris, Leanne, Jeeves, Mark, Walker, Sarah A, Ward, Simon E and Mancini, Erika J (2020) Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2. Oncotarget, 11. pp. 1737-1748. ISSN 1949-2553

Morgan, R G, Liddiard, K, Pearn, L, Pumford, S L, Burnett, A K, Darley, R L and Tonks, A (2013) γ-Catenin is expressed throughout normal human hematopoietic development and is required for normal PU.1-dependent monocyte differentiation. Leukemia, 27 (10). pp. 2096-2100. ISSN 1476-5551

Morgan, R G, Pearn, L, Liddiard, K, Pumford, S L, Burnett, A K, Tonks, A and Darley, R L (2013) γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia, 27 (2). pp. 336-43. ISSN 1476-5551

Morgan, Rhys G, Ridsdale, Jenna, Payne, Megan, Heesom, Kate J, Wilson, Marieangela C, Davidson, Andrew, Greenhough, Alexander, Davies, Sara, Williams, Ann C, Blair, Allison, Waterman, Marian L, Tonks, Alex and Darley, Richard L (2019) LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells. Haematologica, 104 (7). pp. 1365-1377. ISSN 1592-8721

Morgan, Rhys G, Ridsdale, Jenna, Tonks, Alex and Darley, Richard L (2014) Factors affecting the nuclear localization of β-catenin in normal and malignant tissue. Journal of Cellular Biochemistry, 115 (8). pp. 1351-1361. ISSN 0730-2312

N

Narwani, Vishal, Gabriel, Joseph, Boyd, Kevin and Chevassut, Timothy (2015) Absolute lymphocyte count at day 29 of treatment is a powerful predictor of outcome in multiple myeloma. Clinical Lymphoma, Myeloma & Leukemia, 15 (4). pp. 222-226. ISSN 2152-2650

Ngo, Greg, Hyatt, Sam, Grimstead, Julia, Jones, Rhiannon, Hendrickson, Eric, Pepper, Chris and Baird, Duncan (2018) PARP inhibition prevents escape from a telomere-driven crisis and inhibits cell immortalisation. Oncotarget, 9 (101). pp. 37549-37563. ISSN 1949-2553

Nichols, Eva-Maria, Jones, Rachael, Pepper, Chris J, Fegan, Chris and Marchbank, Kevin J (2015) A CD21 low phenotype, with no evidence of autoantibodies to complement proteins, is consistent with a poor prognosis in CLL. Oncotarget, 6 (32). pp. 32669-32680. ISSN 1949-2553

Norman, Louis, Tarrant, Paul and Chevassut, Timothy (2014) TET2 inhibits differentiation of embryonic stem cells but does not overcome methylation-induced gene silencing. Bone Marrow Research, 2014. p. 986571. ISSN 2090-2999

Norris, Kevin, Hillmen, Peter, Rawstron, Andrew, Hills, Robert, Baird, Duncan M, Fegan, Christopher D and Pepper, Chris (2019) Telomere length predicts for outcome to FCR chemotherapy in CLL. Leukemia. ISSN 0887-6924

O

O'Brien, Emma Conway, Prideaux, Steven and Chevassut, Timothy (2014) The epigenetic landscape of acute myeloid leukemia. Advances in Hematology, 2014 (103175). pp. 1-15. ISSN 1687-9104

P

Palermo, Richard D, Webb, Helen M, Gunnell, Andrea and West, Michelle J (2008) Regulation of transcription by the Epstein-Barr virus nuclear antigen EBNA 2. Biochemical Society Transactions, 36 (4). pp. 625-8. ISSN 0300-5127

Palermo, Richard D, Webb, Helen M and West, Michelle J (2011) RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus. PLoS Pathogens, 7 (10). e1002334. ISSN 1553-7374

Parry, Helen Marie, Damery, Sarah, Hudson, Christopher, Maurer, Matthew J, Cerhan, James R, Pachnio, Annette, Begum, Jusnara, Slager, Susan L, Fegan, Christopher, Man, Stephen, Pepper, Christopher, Shanafelt, Tait D., Pratt, Guy and Moss, Paul A H (2016) Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia. American Journal of Hematology, 91 (8). pp. 776-781. ISSN 0361-8609

Pasikowska, Marta, Walsby, Elisabeth, Apollonio, Benedetta, Cuthill, Kirsty, Phillips, Elizabeth, Coulter, Eve, Longhi, Maria Serena, Ma, Yun, Yallop, Deborah, Barber, Linda D, Patten, Piers, Fegan, Chris, Ramsay, Alan G, Pepper, Chris, Devereux, Stephen and Buggins, Andrea G S (2016) Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration. Blood, 128 (4). pp. 563-573. ISSN 1528-0020

Pepper, C, Buggins, A G S, Jones, C H, Walsby, E J, Forconi, F, Pratt, G, Devereux, S, Stevenson, F K and Fegan, C (2014) Phenotypic heterogeneity in IGHV-mutated CLL patients has prognostic impact and identifies a subset with increased sensitivity to BTK and PI3Kδ inhibition. Leukemia, 29. pp. 744-747. ISSN 0887-6924

Pepper, Chris, Tu, Henry, Morrill, Paul, Garcia-Rates, Sara, Fegan, Chris and Greenfield, Susan (2017) Tumor cell migration is inhibited by a novel therapeutic strategy antagonizing the alpha-7 receptor. Oncotarget, 14 (8). pp. 11414-11424. ISSN 1949-2553

Phillips, Rupert, Chaudry, Sabah and Chevassut, Timothy (2017) [Correspondence] Clonal hematopoiesis and atherosclerosis. New England Journal of Medicine, 377 (14). pp. 1400-1402. ISSN 0028-4793

Prideaux, Steven M, Conway O'Brien, Emma and Chevassut, Timothy J (2014) The RAG Model: a new paradigm for genetic risk stratification in multiple myeloma. Bone Marrow Research, 2014. a526568. ISSN 2090-2999

Prideaux, Steven M, O'Brien, Emma Conway and Chevassut, Timothy J (2014) The genetic architecture of multiple myeloma. Advances in Hematology, 2014 (864058). pp. 1-16. ISSN 1687-9104

R

Rau, Rachel E, Rodriguez, Benjamin A, Luo, Min, Jeong, Mira, Rosen, Allison, Rogers, Jason H, Campbel, Carly T, Daigle, Scott R, Deng, Lishing, Song, Yongcheng, Sweet, Steve, Chevassut, Timothy, Andreeff, Michael, Kornblau, Steven M, Li, Wei and Goodell, Margaret A (2016) DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood, 128 (7). pp. 971-981. ISSN 0006-4971

Reddy, Udaya, Bewick, Jessica, Good, Catriona, Chevassut, Timothy and Das-Purkayastha, Prodip K (2012) Diffuse large B-cell lymphoma: an unusual cause of severe otalgia and facial palsy. BMJ Case Reports, 2012. ISSN 1757-790X

Reddy, Udaya, Mallepaddi, Nageswara Rao and Chevassut, Timothy J (2015) High INR on warfarin. BMJ, 350. h1282-h1282. ISSN 0959-8138

Rider, Tom, Powell, Robert, Gover, Rebecca, Ansell, Richard, Bastow, Sarah, Ghurye, Rohit R, Stewart, Helen and Chevassut, Timothy (2013) Molecular detection of BRAF-V600E is superior to flow cytometry for disease evaluation in hairy cell leukaemia. Hematological Oncology, 32 (3). pp. 158-161. ISSN 0278-0232

Robinson, Sophie R, Oliver, Antony W, Chevassut, Timothy J and Newbury, Sarah F (2015) The 3' to 5' exoribonuclease DIS3: from structure and mechanisms to biological functions and role in human disease. Biomolecules, 5 (3). pp. 1515-1539. ISSN 2218-273X

Robinson, Sophie R, Viegas, Sandra C, Matos, Rute G, Domingues, Susana, Bedir, Marisa, Stewart, Helen J S, Chevassut, Timothy, Oliver, Antony W, Arraiano, Cecilia M and Newbury, Sarah F (2018) DIS3 isoforms vary in their endoribonuclease activity and are differentially expressed within haematological cancers. Biochemical Journal, 475 (12). pp. 2091-2105. ISSN 0264-6021

Robinson, Stephen D, Gabriel, Joseph, Webb, Andrew, Corbett, Timothy, Johnston, Rosalynd, Wright, David and Chevassut, Timothy (2015) Immunohistochemical prognostication in diffuse large B cell lymphoma: a single centre six year retrospective analysis. Leukemia & Lymphoma, 56 (10). pp. 2975-2977. ISSN 1042-8194

S

Sava, G P, Speedy, H E, Di Bernardo, M C, Dyer, M J S, Holroyd, A, Sunter, N J, Marr, H, Mansouri, L, Deaglio, S, Karabon, L, Frydecka, I, Jamroziak, K, Woszczyk, D, Juliusson, G, Smedby, K E, Jayne, S, Majid, A, Wang, Y, Dearden, C, Hall, A G, Mainou-Fowler, T, Jackson, G H, Summerfield, G, Harris, R J, Pettitt, A R, Allsup, D J, Bailey, J R, Pratt, G, Pepper, C, Fegan, C, Rosenquist, R, Catovsky, D, Allan, J M and Houlston, R S (2014) Common variation at 12q24.13 (OAS3) influences chronic lymphocytic leukemia risk. Leukemia, 29 (3). pp. 748-751. ISSN 0887-6924

Schlick, Sandra N, Wood, C David, Gunnell, Andrea, Webb, Helen M, Khasnis, Sarika, Schepers, Aloys and West, Michelle J (2011) Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells. PLoS ONE, 6 (12). e28638. ISSN 1932-6203

Sewell, H, Tanaka, T, Omari, K E, Mancini, E J, Cruz, A, Fernandez-Fuentes, N, Chambers, J and Rabbitts, T H (2015) Conformational flexibility of the oncogenic protein LMO2 primes the formation of the multi-protein transcription complex. Scientific Reports, 4 (1). a3643. ISSN 2045-2322

Simpson, K, Jones, R E, Grimstead, J W, Hills, R, Pepper, C and Baird, D M (2015) Telomere fusion threshold identifies a poor prognostic subset of breast cancer patients. Molecular Oncology, 9 (6). pp. 1186-1193. ISSN 15747891

Speedy, Helen E, Di Bernardo, Maria Chiara, Sava, Georgina P, Dyer, Martin J S, Holroyd, Amy, Wang, Yufei, Sunter, Nicola J, Mansouri, Larry, Juliusson, Gunnar, Smedby, Karin E, Roos, Göran, Jayne, Sandrine, Majid, Aneela, Dearden, Claire, Hall, Andrew G, Mainou-Fowler, Tryfonia, Jackson, Graham H, Summerfield, Geoffrey, Harris, Robert J, Pettitt, Andrew R, Allsup, David J, Bailey, James R, Pratt, Guy, Pepper, Chris, Fegan, Chris, Rosenquist, Richard, Catovsky, Daniel, Allan, James M and Houlston, Richard S (2013) A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. Nature Genetics, 46 (1). pp. 56-60. ISSN 1061-4036

Stewart, Helen, Chaudry, Sabah, Crichlow, Asante, Feilding, Freya Luling and Chevassut, Timothy (2018) BET inhibition suppresses S100A8 and S100A9 expression in acute myeloid leukemia cells and synergises with daunorubicin in causing cell death. Bone Marrow Research, 2018 (574295). ISSN 2090-2999

Stewart, Helen, Kishikova, Lyudmila, Powell, Fiona, Wheatley, Sally Paula and Chevassut, Timothy (2011) The polo-like kinase inhibitor BI 2536 exhibits potent activity against malignant plasma cells and represents a novel therapy in multiple myeloma. Experimental Hematology, 39 (3). pp. 330-338. ISSN 0301-472X

Stewart, Helen J S, Shalit, Ella, Halliday, Loryn, Morey, Dominic and Chevassut, Timothy J (2015) Letter to the editor: acute myeloid leukemia cells exhibit selective down-regulation of DNMT3A isoform 2. Leukemia & Lymphoma, 56 (12). pp. 3445-3448. ISSN 1042-8194

Strefford, J C, Kadalayil, L, Forster, J, Rose-Zerilli, M J J, Parker, A, Lin, T T, Heppel, N, Norris, K, Gardiner, A, Davies, Z, Gonzalez de Castro, D, Else, M, Steele, A J, Parker, H, Stankovic, T, Pepper, C, Fegan, C, Baird, D, Collins, A, Catovsky, D and Oscier, D G (2015) Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial. Leukemia, 29 (12). pp. 2411-2414. ISSN 0887-6924

T

Teagle, Alexandra R, Barton, Hannah, Charles-Edwards, Elizabeth, Dizdarevic, Sabina and Chevassut, Timothy (2017) Use of FDG PET/CT in identification of bone marrow involvement in diffuse large B cell lymphoma and follicular lymphoma: comparison with iliac crest bone marrow biopsy. Acta Radiologica. ISSN 0284-1851

Tofts, Paul S, Chevassut, Timothy, Cutajar, Marica, Dowell, Nicholas G and Peters, A Michael (2011) Doubts concerning the recently reported human neutrophil lifespan of 5.4 days. Blood, 117 (22). pp. 6050-6052. ISSN 0006-4971

W

Wadley, Alex J, Holliday, Adrian, Morgan, Rhys G, Heesom, Kate J, Aldred, Sarah, Peters, Derek M, Bueno, Allain A and Coles, Steven J (2018) Preliminary evidence of reductive stress in human cytotoxic T-cells following exercise. Journal of Applied Physiology, 125 (2). pp. 586-595. ISSN 8750-7587

Wadley, Alex J, Morgan, Rhys, Heesom, Kate J, Hole, Paul S and Coles, Steven J (2018) Detecting intracellular thiol redox state in leukaemia and heterogeneous immune cell populations: an optimised protocol for digital flow cytometers. MethodsX, 5. pp. 1473-1483. ISSN 2215-0161

Wadley, Alex J, Morgan, Rhys G, Darley, Richard L, Hole, Paul S and Coles, Steven J (2019) Using flow cytometry to detect and measure intracellular thiol redox status in viable T cells from heterogeneous populations. Methods in Molecular Biology. pp. 53-70. ISSN 1064-3745

Walsby, Elisabeth, Buggins, Andrea, Devereux, Stephen, Jones, Ceri, Pratt, Guy, Brennan, Paul, Fegan, Chris and Pepper, Chris (2014) Development and characterization of a physiologically relevant model of lymphocyte migration in chronic lymphocytic leukemia. Blood, 123 (23). pp. 3607-3617. ISSN 0006-4971

Went, Molly, Sud, Amit, Speedy, Helen, Sunter, Nicola J, Försti, Asta, Law, Philip J, Johnson, David C, Mirabella, Fabio, Holroyd, Amy, Li, Ni, Orlando, Giulia, Weinhold, Niels, van Duin, Mark, Chen, Bowang, Mitchell, Jonathan S, Mansouri, Larry, Juliusson, Gunnar, Smedby, Karin E, Jayne, Sandrine, Majid, Aneela, Dearden, Claire, Allsup, David J, Bailey, James R, Pratt, Guy, Pepper, Chris, Fegan, Chris, Rosenquist, Richard, Kuiper, Rowan, Stephens, Owen W, Bertsch, Uta, Broderick, Peter, Einsele, Hermann, Gregory, Walter M, Hillengass, Jens, Hoffmann, Per, Jackson, Graham H, Jöckel, Karl-Heinz, Nickel, Jolanta, Nöthen, Markus M., da Silva Filho, Miguel Inacio, Thomsen, Hauke, Walker, Brian A, Broyl, Annemiek, Davies, Faith E, Hansson, Markus, Goldschmidt, Hartmut, Dyer, Martin J S, Kaiser, Martin, Sonneveld, Pieter, Morgan, Gareth J, Hemminki, Kari, Nilsson, Björn, Catovsky, Daniel, Allan, James M and Houlston, Richard S (2018) Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology. Blood Cancer Journal, 9 (1). pp. 1-9. ISSN 2044-5385

West, Michelle (2017) Chromatin reorganisation in Epstein-Barr virus-infected cells and its role in cancer development. Current Opinion in Virology, 26. pp. 149-155. ISSN 1879-6257

West, Michelle J, Webb, Helen M, Sinclair, Alison J and Woolfson, Derek N (2004) Biophysical and Mutational Analysis of the Putative bZIP Domain of Epstein-Barr Virus EBNA 3C. Journal of Virology, 78 (17). pp. 9431-9445. ISSN 0022-538X

West, Michelle J. (2006) Structure and function of the Epstein-Barr virus transcription factor, EBNA 3C. Current Protein and Peptide Science, 7 (2). pp. 123-136. ISSN 1389-2037

Williams, Jenna, Heppel, Nicole H, Britt-Compton, Bethan, Grimstead, Julia W, Jones, Rhiannon E, Tauro, Sudhir, Bowen, David T, Knapper, Steven, Groves, Michael, Hills, Robert K, Pepper, Chris, Baird, Duncan M and Fegan, Chris (2017) Telomere length is an independent prognostic marker in MDS but not in de novo AML. British Journal of Haematology, 178 (2). pp. 240-249. ISSN 0007-1048

Wood, C David, Carvell, Thomas, Gunnell, Andrea, Ojeniyi, Opeoluwa O, Osborne, Cameron and West, Michelle J (2018) Enhancer control of MicroRNA miR-155 expression in EpsteinBarr virus-infected B cells. Journal of Virology, 92 (19). e000716-18 1 1. ISSN 0022-538X

Z

Zabkiewicz, Joanna, Pearn, Lorna, Hills, Robert K, Morgan, Rhys G, Tonks, Alex, Burnett, Alan K and Darley, Richard L (2014) The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. Haematologica, 99 (5). pp. 858-864. ISSN 1592-8721