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- Research Centres and Groups (128)
- Genome Damage and Stability Centre (128)
A
Abramowicz, Iga, Carpenter, Gillian, Alfieri, Mariaevelina, Colnaghi, Rita, Outwin, Emily, Parent, Philippe, Thauvin-Robinet, Christel, Iaconis, Daniela, Franco, Brunella and O'Driscoll, Mark (2017) Oral-Facial-Digital syndrome Type I cells exhibit impaired DNA repair; unanticipated consequences of defective OFD1 outside of the cilia network. Human Molecular Genetics, 26 (1). pp. 19-32. ISSN 0964-6906
Addis Jones, Owen, Tiwari, Ankana, Olukoga, Tomisin, Herbert, Alex and Chan, Kok-Lung (2019) PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling. Nature Communications, 10 (1). pp. 1-17. ISSN 2041-1723
Akera, Takashi, Goto, Yuhei, Sato, Masamitsu, Yamamoto, Masayuki and Watanabe, Yoshinori (2015) Mad1 promotes chromosome congression by anchoring a kinesin motor to the kinetochore. Nature Cell Biology, 17 (9). pp. 1124-1133. ISSN 1465-7392
Alcantara, Diana, Elmslie, Frances, Tetreault, Martine, Bareke, Eric, Hartley, Taila, Care4Rare Consortium, , Majewski, Jacek, Boycott, Kym, Innes, A Micheil, Dyment, David A and O'Driscoll, Mark (2017) SHORT syndrome due to a novel de novo mutation in PRKCE (Protein Kinase Cɛ) impairing TORC2-dependent AKT activation. Human Molecular Genetics, 26 (19). pp. 3713-3721. ISSN 1460-2083
Alcantara, Diana, Timms, Andrew E, Gripp, Karen, Baker, Laura, Park, Kaylee, Collins, Sarah, Cheng, Chi, Stewart, Fiona, Mehta, Sarju G, Saggar, Anand, Sztriha, László, Zombor, Melinda, Caluseriu, Oana, Mesterman, Ronit, Van Allen, Margot I, Jacquinet, Adeline, Ygberg, Sofia, Bernstein, Jonathan A, Wenger, Aaron M, Guturu, Harendra, Bejerano, Gill, Gomez-Ospina, Natalia, Lehman, Anna, Alfei, Enrico, Pantaleoni, Chiara, Conti, Valerio, Guerrini, Renzo, Moog, Ute, Graham Jr., John M, Hevner, Robert, Dobyns, William B, O'Driscoll, Mark and Mirzaa, Ghayda M (2017) Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly. Brain, 140 (10). pp. 2610-2622. ISSN 0006-8950
B
Bailey, Laura and Doherty, Aidan (2017) Mitochondrial DNA replication: a PrimPol perspective. Biochemical Society Transactions, 45 (2). pp. 513-529. ISSN 0300-5127
Bailey, Laura J, Bianchi, Julie and Doherty, Aidan J (2019) PrimPol is required for the maintenance of efficient nuclear and mitochondrial DNA replication in human cells. Nucleic Acids Research, 47 (8). pp. 4026-4038. ISSN 0305-1048
Barg-Wojas, Anna, Muraszko, Jakub, Kramarz, Karol, Schirmeisen, Kamila, Baranowska, Gabriela, Carr, Antony M and Dziadkowiec, Dorota (2020) S. pombe DNA translocases Rrp1 and Rrp2 have distinct roles at centromeres and telomeres that ensure genome stability. Journal of Cell Science. ISSN 1477-9137
Baxter, Jon (2012) A model for chromosome condensation based on the interplay between condensin and topoisomerase II. Trends in Genetics, 28 (3). pp. 110-117. ISSN 0168-9525
Baxter, Jonathan, Oliver, Antony W and Schalbetter, Stephanie A (2019) Are SMC complexes loop extruding factors? Linking theory with fact. BioEssays, 41 (1). 1800182 1-10. ISSN 1521-1878
Benson, Matthew, Tinsley, Caroline, Waite, Aidan, Carlisle, Francesca, Sweet, Steve, Ehler, Elisabeth, George, Christopher, Lai, Anthony, Martin-Rendon, Enca and Blake, Derek (2017) Ryanodine receptors are part of the myospryn complex in cardiac muscle. Scientific Reports, 7 (6312). pp. 1-12. ISSN 2045-2322
Bertoletti, Federica, Cea, Valentina, Liang, Chih-Chao, Lanati, Taiba, Maffia, Antonio, Avarello, Mario D M, Cipolla, Lina, Lehmann, Alan R, Cohn, Martin A and Sabbioneda, Simone (2017) Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle. Nucleic Acids Research, 45 (16). pp. 9441-9454. ISSN 1362-4962
Biehs, Ronja, Steinlage, Monika, Barton, Oliva, Juhász, Szilvia, Künzel, Julia, Spies, Julian, Shibata, Atsushi, Jeggo, Penny and Löbrich, Markus (2017) DNA double-strand break resection occurs during non-homologous end joining in G1 but is distinct from resection during homologous recombination. Molecular Cell, 65 (4). pp. 671-684. ISSN 1097-2765
Bigot, Nicolas, Day, Matthew, Baldock, Robbie A, Watts, Felicity Z, Oliver, Antony W and Pearl, Laurence H (2019) Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. eLIfe, 8. a44353 1-28. ISSN 2050-084X
Blanco, Miguel G, Matos, Joao, Rass, Ulrich, Ip, Stephen C Y and West, Stephen C (2010) Functional overlap between the structure-specific nucleases Yen1 and Mus81-Mms4 for DNA-damage repair in S. cerevisiae. DNA repair, 9 (4). pp. 394-402. ISSN 1568-7864
Bone, Frédérique, Hopkins, Michael M, Rafols, Ismael, Molas-Gallart, Jordi, Tang, Puay, Davey, Gail and Carr, Antony (2019) DARE to be different? Applying diversity heuristics to the analysis of collaborative research. Working Paper. University of Sussex, Brighton, UK.
Breslin, Claire, Mani, Rajam S, Fanta, Mesfin, Hoch, Nicolas, Weinfield, Michael and Caldecott, Keith W (2017) The RIR motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair. Journal of Biological Chemistry, 292. pp. 16024-16031. ISSN 1083-351X
C
Calmels, Nadege, Botta, Elena, Jia, Nan, Fawcett, Heather, Nardo, Tiziana, Nakazawa, Yuka, Lanzafame, Manuela, Moriwaki, Shinichi, Sugita, Katsuo, Kubota, Masaya, Orbinger, Cathy, Spitz, Marie-Aude, Stefanini, Miria, Laugel, Vincent, Orioli, Donata, Ogi, Tomoo and Lehmann, Alan Robert (2018) Functional and clinical relevance of novel mutations in a large cohort of patients with Cockayne syndrome. Journal of Medical Genetics, 55 (5). pp. 329-343. ISSN 0022-2593
Campillo-Funollet, Eduard, Venkataraman, Chandrasekhar and Madzvamuse, Anotida (2019) Bayesian parameter identification for Turing systems on stationary and evolving domains. Bulletin of Mathematical Biology, 81 (1). pp. 81-104. ISSN 0092-8240
Canela, Andres, Marman, Yaakov, Huang, Shar-yin N, Wutz, Gordana, Tang, Wen, Zagnol-iVieira, Guido, Callen, Elsa, Wong, Nancy, Day, Amanda, Peters, Jan-Michael, Pommier, Yves, Caldecott, Keith W and Nussenzweig, André (2019) Topoisomerase II-Induced chromosome breakage and translocation is determined by chromosome architecture and transcriptional activity. Molecular Cell. ISSN 1097-2765
Cannavo, Elda, Johnson, Dominic, Andres, Sara, Kissling, Vera, Reinert, Julia, Garcia, Valerie, Erie, Dorothy, Hess, Daniel, Thomä, Nicolas, Enchev, Radoslav, Peter, Matthias, Williams, Scott, Neale, Matt and Cejka, Petr (2018) Regulatory control of DNA end resection by Sae2 phosphorylation. Nature Communications, 9. p. 4016. ISSN 2041-1723
Caser Tena, Teresa, Maerz, Lars, Szafranski, Karol, Groth, Marco, Blatte, Tamara, Donow, Cornelia, Matysik, Sabrina, Walther, Paul, Jeggo, Penelope A, Burkhalter, Martin and Philipp, Melanie (2019) Resting cells rely on the DNA helicase component MCM2 to build cilia. Nucleic Acids Research, 47 (1). pp. 134-151. ISSN 0305-1048
Castañeda-García, A, Prieto, A I, Rodríguez-Beltrán, J, Alonso, N, Cantillon, D, Costas, C, Pérez-Lago, L, Zegeye, E D, Herranz, M, Plociński, P, Tonjum, T, García de Viedma, D, Paget, M, Waddell, S J, Rojas, A M, Doherty, A J and Blázquez, J (2017) A non-canonical mismatch repair pathway in prokaryotes. Nature Communications, 8. a14246. ISSN 2041-1723
D
Daigaku, Yasukazu, Etheridge, Thomas J, Nakazawa, Yuka, Nakayama, Mayumi, Watson, Adam T, Miyabe, Izumi, Ogi, Tomoo, Osborne, Mark A and Carr, Antony M (2017) PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast. PLoS Genetics, 13 (5). e1006789. ISSN 1553-7390
Dave, Anoushka, Pai, Chen-Chun, Durley, Samuel C, Hulme, Lydia, Sarkar, Sovan, Wee, Boon-Yu, Prudden, John, Tinline-Purvis, Helen, Cullen, Jason K, Walker, Carol, Watson, Adam, Carr, Antony M, Murray, Johanne M and Humphrey, Timothy C (2019) Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks. Nucleic Acids Research. pp. 1-14. ISSN 0305-1048
Deegan, Tom D, Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T P and Labib, Karim P M (2019) Pif1-Family helicases support fork convergence during DNA replication termination in eukaryotes. Molecular Cell, 74 (2). 231-244.e9. ISSN 1097-4164
d'Adda di Fagagna, Fabrizio, Weller, Geoffrey R, Doherty, Aidan and Jackson, Stephen P (2003) The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku. EMBO Reports, 4 (1). pp. 47-52. ISSN 1469-221X
F
Falquet, Benoît and Rass, Ulrich (2019) Structure-specific endonucleases and the resolution of chromosome underreplication. Genes, 10 (3). p. 232. ISSN 2073-4425
Falquet, Benoît and Rass, Ulrich (2017) A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative helicase. Microbial Cell, 4 (1). pp. 32-34. ISSN 2311-2638
Falquet, Benoît, Ölmezer, Gizem, Enkner, Franz, Klein, Dominique, Challa, Kiran, Appanah, Rowin, Gasser, Susan M and Rass, Ulrich (2020) Disease-associated DNA2 nuclease–helicase protects cells from lethal chromosome under-replication. Nucleic Acids Research, 48 (13). pp. 7265-7278. ISSN 1362-4962
Fleck, Oliver, Fahnøe, Ulrik, Vyff Løvschal, Katrine, Uwamahoro Gasasira, Marie-Fabrice, Marinova, Irina N, Kragelund, Birthe B, Carr, Antony M, Hartsuiker, Edgar, Holmberg, Christian and Nielsen, Olaf (2017) Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-Mediated inhibition of replication. Genes, 8 (5). a128. ISSN 2073-4425
Fontana, Gabriele A, Hess, Daniel, Reinert, Julia K, Mattarocci, Stefano, Falquet, Benoît, Klein, Dominique, Shore, David, Thomä, Nicolas H and Rass, Ulrich (2019) Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane. Nature Communications, 10 (2535). pp. 1-14. ISSN 2041-1723
Fontana, Gabriele A and Rass, Ulrich (2019) Compartmentalized DNA repair: Rif1 S-acylation links DNA double-strand break repair to the nuclear membrane. Molecular & Cellular Oncology. ISSN 2372-3556
Fontana, Gabriele A, Reinert, Julia K, Thomä, Nicolas H and Rass, Ulrich (2018) Shepherding DNA ends: Rif1 protects telomeres and chromosome breaks. Microbial Cell, 5 (7). pp. 327-343. ISSN 2311-2638
G
Gittens, William H, Johnson, Dominic J, Allison, Rachal M, Cooper, Tim J, Thomas, Holly and Neale, Matthew J (2019) A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome. Nature Communications, 10. a4846. ISSN 2041-1723
Goncalves, Maria B, Moehlin, Julien, Clarke, Earl, Grist, John, Hobbs, Carl, Carr, Antony M, Jack, Julian, Mendoza-Parra, Marco Antonio and Corcoran, Jonathan P T (2019) RARb agonist drug (C286) demonstrates efficacy in a pre-clinical neuropathic pain model restoring multiple pathways via DNA repair mechanisms. iScience, 20. pp. 554-566. ISSN 2589-0042
Goto, Yuhei, Yamagishi, Yuya, Shintomi-Kawamura, Miyuki, Abe, Mayumi, Tanno, Yuji and Watanabe, Yoshinori (2017) Pds5 regulates sister-chromatid cohesion and chromosome bi-orientation through a conserved protein interaction module. Current Biology, 27 (7). pp. 1005-1012. ISSN 0960-9822
Guilliam, Thomas A, Brissett, Nigel C, Ehlinger, Aaron, Keen, Benjamin A, Kolesar, Peter, Taylor, Elaine, Bailey, Laura J, Lindsay, Howard, Chazin, Walter J and Doherty, Aidan J (2017) Molecular basis for PrimPol recruitment to replication forks by RPA. Nature Communications, 8. a15222. ISSN 2041-1723
Gómez-Herreros, Fernando, Zagnoli-Vieira, Guido, Ntai, Ioanna, Martínez-Macías, María Isabel, Anderson, Rhona M, Herrero-Ruíz, Andrés and Caldecott, Keith W (2017) TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription. Nature Communications, 8 (1). a233 1-9. ISSN 2041-1723
H
Hall, Janet, Jeggo, Penny A, West, Catherine, Gomolka, Maria, Quintens, Roeal, Badie, Christophe, Laurent, Olivier, Aerts, An, Anastaov, Nataša, Azimzadehh, Omid and Others, (2017) Ionizing radiation biomarkers in epidemiological studies –An update. Mutation Research - Reviews, 771. pp. 59-84. ISSN 1383-5742
Hallett, Stephen T, Campbell Harry, Isabella, Schellenberger, Pascale, Zhou, Lihong, Cronin, Nora B, Baxter, Jonathan, Etheridge, Thomas J, Murray, Johanne M and Oliver, Antony W (2022) Cryo-EM Structure of the Smc5/6 holocomplex. Nucleic Acids Research, 50 (16). pp. 9505-9520. ISSN 0305-1048
Hallett, Stephen T, Pastok, Martyna W, Morgan, R Marc L, Wittner, Anita, Blundell, Katie L I M, Felletar, Ildiko, Wedge, Stephen R, Prodromou, Chrisostomos, Noble, Martin E M, Pearl, Laurence H and Endicott, Jane A (2017) Differential regulation of G1 CDK complexes by the Hsp90-Cdc37 chaperone system. Cell Reports, 21 (5). pp. 1386-1398. ISSN 2211-1247
Hanzlikova, Hana, Gittens, William, Krejcikova, Katerina, Zeng, Zhihong and Caldecott, Keith W (2017) Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin. Nucleic Acids Research, 45 (5). pp. 2546-2557. ISSN 1362-4962
Hanzlikova, Hana, Kalasova, Ilona, Demin, Annie A, Pennicott, Lewis E, Cihlarova, Zuzana and Caldecott, Keith W (2018) The importance of Poly(ADP-Ribose) Polymerase as a sensor of unligated Okazaki fragments during DNA replication. Molecular Cell, 71 (2). pp. 319-331. ISSN 1097-2765
Hegarat, Nadia, Vesely, Clare, Peter, Nisha, Oliver, Antony and Hochegger, Helfrid (2014) PP2A/B55 and Fcp1 regulate Greatwall and Ensa desphorylation during mitotic exit. PLoS Genetics, 10 (2). e1004259 1. ISSN 1553-7390
Hoch, Nicolas C, Hanzlikova, Hana, Rulten, Stuart L, Tétreault, Martine, Komulainen, Emilia, Ju, Limei, Hornyak, Peter, Zeng, Zhihong, Gittens, William, Rey, Stephanie A, Staras, Kevin, Mancini, Grazia M S, McKinnon, Peter J, Wang, Zhao-Qi, Wagner, Justin D, Care4Rare Canada Consortium, , Yoon, Grace and Caldecott, Keith W (2017) XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia. Nature, 541. pp. 87-91. ISSN 0028-0836
I
Ip, Stephen C Y, Rass, Ulrich, Blanco, Miguel G, Flynn, Helen R, Skehel, J Mark and West, Stephen C (2008) Identification of Holliday junction resolvases from humans and yeast. Nature, 456 (7220). pp. 357-61. ISSN 0028-0836
J
Jeggo, Penny and Barazzuol, Lara (2017) In vivo sensitivity of the embryonic and adult neural stem cell compartments to low-dose radiation. Journal of Radiation Research, 57 (S1). i2-i10. ISSN 0449-3060
Jeggo, Penny, Barazzuol, Lara and Ju, Limei (2017) A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biology, 15 (5). e2001264 1-25. ISSN 1544-9173
Jeggo, Penny and Löbrich, Markus (2017) A process of resection-dependent nonhomologous end joining involving the goddess Artemis. Trends in Biochemical Sciences, 42 (9). pp. 690-701. ISSN 0968-0004
Jeggo, Penny A, Downs, Jessica A and Gasser, Susan M (2017) Chromatin modifiers and remodellers in DNA repair and signalling. Philosophical Transactions B: Biological Sciences, 372 (1731). pp. 1-6. ISSN 0962–8436
Jeggo, Penny A and Löbrich, Markus (2017) [Editorial] DNA non-homologous end-joining enters the resection arena. Oncotarget, 8 (55). pp. 93317-93318. ISSN 1949-2553
K
Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J, Stewart, Grant S, Wollnick, Bernd, Yigit, Gökhan and Caldecott, Keith W (2019) Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ. Neurology Genetics, 5 (2). pp. 1-7. ISSN 2376-7839
Karasozen, Yigit, Osbun, Joshua W, Parada, Carolina Angelica, Busald, Tina, Tatman, Philip, Gonzalez-Cuyar, Luis F, Hale, Christopher J, Alcantara, Diana, O'Driscoll, Mark, Dobyns, William B, Murray, Mitzi, Kim, Louis J, Byers, Peter, Dorschner, Michael O and Ferreira, Manuel (2019) Somatic PDGFRB activating variants in fusiform cerebral aneurysms. American Journal of Human Genetics, 104 (5). pp. 968-976. ISSN 1537-6605
Keszthelyi, Andrea, Minchell, Nicola and Baxter, Jon (2016) The causes and consequences of topological stress during DNA replication. Genes, 7 (12). p. 134. ISSN 2073-4425
Kobayashi, Kaori, Guilliam, Thomas A, Tsuda, Masataka, Yamamoto, Junpei, Bailey, Laura J, Iwai, Shigenori, Takeada, Shunichi, Doherty, Aidan J and Hirota, Kouji (2016) Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain terminating nucleosides. Cell Cycle, 15 (15). pp. 1997-2008. ISSN 1538-4101
Kukalev, Alexander, Ng, Yiu-Ming, Ju, Limei, Saidi, Amal, Lane, Sophie, Mondragon, Angeles, Dormann, Dirk, Walker, Sophie E, Grey, William, Ho, Philip Wing-Lok, Stephens, David N, Carr, Antony M, Lamsa, Karri, Tse, Eric and Yu, Veronica (2016) Deficiency of Cks1 leads to learning and long-term memory defects and p27 dependentformation of neuronal cofilin aggregates. Cerebral Cortex, 27 (1). pp. 11-23. ISSN 1047-3211
Kustatscher, Georg, Hégarat, Nadia, Willis, Karen L H, Furlan, Cristina, Bukowski-Wills, Jimi-Carlo, Hochegger, Helfrid and Rappsilber, Juri (2014) Proteomics of a fuzzy organelle: interphase chromatin. The EMBO Journal, 33 (6). pp. 648-664. ISSN 0261-4189
L
Lehmann, Alan (2017) Xeroderma pigmentosum is a definite cause of Huntington's disease-like syndrome. Annals of Clinical and Translational Neurology, 5 (1). pp. 102-108. ISSN 2328-9503
Lehmann, Alan R (2009) DNA damage tolerance and translesions synthesis. In: Khanna, Kum Kum and Shiloh, Yosef (eds.) The DNA damage response: implications on cancer formation and treatment. Springer, Dordrecht, pp. 209-234. ISBN 9789048125609
Lemmens, Bennie, Hegarat, Nadia, Akopyan, Karen, Sala-Gaston, Joan, Bartek, Jiri, Hochegger, Helfrid and Lindqvist, Arne (2018) DNA replication determines timing of mitosis by restricting CDK1 and PLK1 activation. Molecular Cell, 71 (1). 117-128.e3. ISSN 1097-2765
Li, Arthur W H, Zabrady, Katerina, Bainbridge, Lewis J, Zabrady, Matej, Naseem-Khan, Sehr, Berger, Madison B, Kolesar, Peter, Cisneros, G Andrés and Doherty, Aidan J (2022) Molecular basis for the initiation of DNA primer synthesis. Nature. ISSN 0028-0836
Li, Zhaobo, Zhou, Lihong, Prodromou, Chrisostomos, Savic, Velibor and Pearl, Laurence H (2017) HECTD3 mediates an HSP90-dependent degradation pathway for protein kinase clients. Cell Reports, 19 (12). pp. 2515-2528. ISSN 2211-1247
M
Maerz, Lars D, Casar Tena, Teresa, Gerhards, Julian, Donow, Cornelia, Jeggo, Penelope A and Philipp, Melanie (2019) Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of origin recognition complex factors. European Journal of Human Genetics, 27 (5). pp. 772-782. ISSN 1018-4813
Martino, Fabrizio, Pal, Mohinder, Muñoz-Hernández, Hugo, Rodríguez, Carlos F, Núñez-Ramírez, Rafael, Gil-Carton, David, Degliesposti, Gianluca, Skehel, J Mark, Roe, S Mark, Prodromou, Chrisostomos, Pearl, Laurence H and Llorca, Oscar (2018) RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nature Communications, 9 (1). ISSN 2041-1723
Mattarocci, Stefano, Reinert, Julia K, Bunker, Richard D, Fontana, Gabriele A, Shi, Tianlai, Klein, Dominique, Cavadini, Simone, Faty, Mahamadou, Shyian, Maksym, Hafner, Lukas, Shore, David, Thomä, Nicolas H and Rass, Ulrich (2017) Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends. Nature Structural and Molecular Biology, 24 (7). pp. 588-595. ISSN 1545-9985
McLean, Angela R, Adlen, Ella K, Cardis, Elisabeth, Elliot, Alex, Goodhead, Dudely T, Harms-Ringdahl, Mats, Hendry, Jolyon H, Hoskin, Peter, Jeggo, Penny A, Mackay, David J C, Muirhead, Colin R, Shepherd, John, Shore, Roy E, Thomas, Geraldine A, Wakeford, Richard and Godfray, H Charles J (2017) A restatement of the natural science evidence base concerning the health effects of low-level ionizing radiation. Proceedings of the Royal Society B, 284. pp. 1-7. ISSN 0080-464
Meisenberg, Cornelia, Pinder, Sarah I, Hopkins, Suzanna R, Wooller, Sarah K, Benstead-Hume, Graeme, Pearl, Frances M G, Jeggo, Penny A and Downs, Jessica A (2019) Repression of transcription at DNA breaks requires cohesin throughout interphase and prevents genome instability. Molecular Cell, 73 (2). 212-223.e7. ISSN 1097-2765
Minchell, Nicola Elizabeth, Keszthelyi, Andrea and Baxter, Jonathan (2020) Cohesin causes replicative DNA damage by trapping DNA topological stress. Molecular cell, 78 (4). pp. 739-751. ISSN 1097-2765
Mirman, Zachary, Lottersberger, Francisca, Takai, Hiroyuki, Kibe, Tatsuya, Gong, Yi, Takai, Kaori, Bianchi, Alessandro, Zimmerman, Michal, Durocher, Daniel and de Lange, Tittia (2018) 53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in. Nature, 560. pp. 112-116. ISSN 0028-0836
Miyabe, Izumi, Mizuno, Ken'ichi, Keszthelyi, Andrea, Daigaku, Yasukazu, Skouteri, Meliti, Mohebi, Saed, Kunkel, Thomas A, Murray, Johanne and Carr, Antony M (2015) Polymerase δ replicates both strands after homologous recombination-dependent fork restart. Nature Structural & Molecular Biology, 22 (11). pp. 932-939. ISSN 1545-9993
Mok, Myth T, Zhou, Jingying, Tang, Wenshu, Zeng, Xuezhen, Oliver, Antony W, Ward, Simon E and Cheng, Alfred S L (2018) CCRK is a novel signalling hub exploitable in cancer immunotherapy. Pharmacology and Therapeutics, 186. pp. 138-151. ISSN 0163-7258
Mothersill, Carmel, Abend, Michael, Bréchignac, Francois, Copplestone, David, Geras'kin, Stanislav, Goodman, Jessica, Horemans, Nele, Jeggo, Penny, McBride, William, Mousseau, Timothy A, O'Hare, Timothy, Papineni, Rao V L, Powathil, Gibin, Schofield, Paul N, Seymour, Colin, Sutcliffe, Jill and Austin, Brian (2018) The tubercular badger and the uncertain curve:- the need for a multiple stressor approach in environmental radiation protection. Environmental Research, 168. pp. 130-140. ISSN 0013-9351
Murfuni, Ivana and Rass, Ulrich (2016) Targeting homologous recombination repair in cancer. In: Kelley, Mark R and Fishel, Melissa L (eds.) DNA Repair in Cancer Therapy. Academic Press, pp. 225-275. ISBN 9780128035825
Murray, Johanne (2017) Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine. PLoS Medicine, 12 (11). e0187775 1-16. ISSN 1549-1277
Murray, Johanne, Watson, Adam and Carr, Antony (2016) [Protocol] Extraction of chromosomal DNA from Schizosaccharomyces pombe. Cold Spring Harbor Protocols, 2016 (5). ISSN 1559-6095
Murray, Johanne, Watson, Adam and Carr, Antony (2016) [Protocol] Identifying products of recombinase-mediated cassette exchange (RMCE) in schizosaccharomyces pombe. Cold Spring Harbor Protocols, 2016 (5). ISSN 1559-6095
Murray, Johanne, Watson, Adam and Carr, Antony (2016) [Protocol]: Transformation of schizosaccharomyces pombe: electroporation procedure. Cold Spring Harbor Protocols, 2016 (4). ISSN 1559-6095
Murray, Johanne M and Carr, Antony M (2018) Integrating DNA damage repair with the cell cycle. Current Opinion in Cell Biology, 52. pp. 120-125. ISSN 0955-0674
Murray, Johanne M, Watson, Adam T and Carr, Antony M (2016) [Protocol] Colony polymerase chain reaction with Schizosaccharomyces pombe. Cold Spring Harbor Protocols, 2016 (5). ISSN 1559-6095
Murray, Johanne M, Watson, Adam T and Carr, Antony M (2016) [Protocol] Molecular genetic tools and techniques in fission yeast. Cold Spring Harbor Protocols, 2016 (5). ISSN 1559-6095
Murray, Johanne M, Watson, Adam T and Carr, Antony M (2016) [Protocol]: Transformation of schizosaccharomyces pombe: protoplast procedure. Cold Spring Harbour Protocols, 2016 (4). ISSN 1559-6095
Murray, Johanne M, Watson, Adam T and Carr, Antony M (2016) [Protocol]Transformation of schizosaccharomyces pombe: lithium acetate/ dimethyl sulfoxide procedure. Cold Spring Harbour Protocols, 2016 (4). ISSN 1559-6095
Muñoz-Hernández, Hugo, Pal, Mohinder, Rodríguez, Carlos F, Fernandez-Leiro, Rafael, Prodromou, Chrisostomos, Pearl, Laurence H and Llorca, Oscar (2019) Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Science Advances, 5 (5). eaaw1616 1-11. ISSN 2375-2548
Muñoz-Hernández, Hugo, Pal, Mohinder, Rodríguez, Carlos F, Prodromou, Chrisostomos, Pearl, Laurence H and Lllorca, Oscar (2018) Advances on the structure of the R2TP/Prefoldin-like complex. In: Djouder, Nabil (ed.) PrefoldinsL the new chaperones. Advances in Experimental Medicine and Biology, 1106 . Springer, Cham, pp. 73-83. ISBN 9783030007362
N
Naiman, Karel, Campillo-Funollet, Eduard, Watson, Adam T, Budden, Alice, Miyabe, Izumi and Carr, Antony M (2021) Replication dynamics of recombination-dependent replication forks. Nature Communications, 12. a923 1-11. ISSN 2041-1723
Nakazawa, Yuka, Yamashita, Shunichi, Lehmann, Alan R and Ogi, Tomoo (2010) A semi-automated non-radiactive system for measuring recovery of RNA synthesis and unscheduled DNA synthesis using ethynyluracil derivatives. DNA Repair, 9 (5). pp. 506-516. ISSN 1568-7864
O
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