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- Research Centres and Groups (35)
- Dementia Research Group (35)
A
Al-Garawi, Z S, McIntosh, B A, Neill-Hall, D, Hatimy, A A, Sweet, S M, Bagley, M C and Serpell, L C (2017) The amyloid architecture provides a scaffold for enzyme-like catalysts. Nanoscale, 9 (30). pp. 10773-10783. ISSN 2040-3364
Al-Garawi, Zahraa S, Kostakis, Georgios E and Serpell, Louise C (2016) Chemically and thermally stable silica nanowires with a β-sheet peptide core for bionanotechnology. Journal of Nanobiotechnology, 14. p. 79. ISSN 1477-3155
Al-Garawi, Zahraa S, Morris, Kyle L, Marshall, Karen E, Eichler, Jutta and Serpell, Louise C (2017) The diversity and utility of amyloid fibrils formed by short amyloidogenic peptides. Interface Focus, 7 (6). p. 20170027. ISSN 2042-8898
Al-Hilaly, Youssra K, Marshall, Karen E, Lutter, Liisa, Biasetti, Luca, Mengham, Kurtis, Harrington, Charles R, Xue, Wei-Feng, Wischik, Claude M and Serpell, Louise C (2022) An additive-free model for tau self-assembly. In: Protein Aggregation. Humana, New York, NY, pp. 163-188. ISBN 9781071625972
Al-Hilaly, Youssra K, Pollack, Saskia J, Rickard, Janet E, Simpson, Michael, Raulin, Ana-C, Baddeley, Thomas, Schellenberger, Pascale, Storey, John M D, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2018) Cysteine-independent inhibition of alzheimer's disease-like paired helical filament assembly by leuco-methylthioninium (LMT). Journal of Molecular Biology, 430 (21). pp. 4119-4131. ISSN 0022-2836
Al‐Hilaly, Youssra K, Foster, Bronwen E, Biasetti, Luca, Lutter, Liisa, Pollack, Saskia J, Rickard, Janet E, Storey, John M D, Harrington, Charles R, Xue, Wei‐Feng, Wischik, Claude M and Serpell, Louise C (2019) Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer’s disease brain. FEBS Letters. pp. 1-7. ISSN 0014-5793
Ardoña, Herdeline Ann M, Draper, Emily R, Citossi, Francesca, Wallace, Matthew, Serpell, Louise C, Adams, Dave J and Tovar, John D (2017) Kinetically controlled coassembly of multichromophoric peptide hydrogelators and the impacts on energy transport. Journal of the American Chemical Society, 139 (25). pp. 8685-8692. ISSN 0002-7863
B
Bukar Maina, Mahmoud, Al-Hilaly, Youssra and Serpell, Louise (2016) Nuclear tau and its potential role in Alzheimer’s disease. Biomolecules, 6 (1). 9 1-20. ISSN 2218-273X
C
Cafferata, Robin M T, Hicks, Ben and von Bastian, Claudia C (2021) Effectiveness of cognitive stimulation for dementia: a systematic review and meta-analysis. Psychological Bulletin, 147 (5). pp. 455-476. ISSN 0033-2909
Christofferson, Andrew J, Al-Garawi, Zahraa S, Todorova, Nevena, Turner, Jack, Del Borgo, Mark Pasqualino, Serpell, Louise C, Aguilar, Marie-Isabel and Yarovsky, Irene (2018) Identifying the coiled-coil triple helix structure of β-peptide nanofibers at atomic resolution. ACS Nano, 12 (9). pp. 9101-9109. ISSN 1936-0851
Clare, Linda, Wu, Yu-Tzu, Jones, Ian Rees, Victor, Christina R, Nelis, Sharon M, Martyr, Anthony, Quinn, Catherine, Litherland, Rachael, Pickett, James, Hindle, John Vincent, Jones, Roy W, John Knapp, Martin Richard, Kopelman, Michael, Morris, Robin G, Rusted, Jennifer M, Thom, Jeanette M, Lamont, Ruth A., Henderson, Catherine, Rippon, Isla, Hillman, Alexandra and Matthews, Fiona (2018) A comprehensive model of factors associated with subjective perceptions of living well with dementia: findings from the IDEAL study. Alzheimer's and Dementia, 14 (7). Supplement P1422-P1423. ISSN 1552-5260
Clare, Linda, Wu, Yu-Tzu, Quinn, Catherine, Jones, Ian R, Victor, Christina R, Nelis, Sharon M, Martyr, Anthony, Litherland, Rachael, Pickett, James A, Hindle, John V, Jones, Roy W, Knapp, Martin, Kopelman, Michael D, Morris, Robin G, Rusted, Jennifer M, Thom, Jeanette M, Lamont, Ruth A, Henderson, Catherine, Rippon, Isla, Hillman, Alexandra and Matthews, Fiona E (2018) A comprehensive model of factors associated with capability to “live well” for family caregivers of people living with mild-to-moderate dementia. Alzheimer Disease & Associated Disorders, 33 (1). pp. 29-35. ISSN 0893-0341
Colquhoun, Catherine, Draper, Emily R, Schweins, Ralf, Marcello, Marco, Vadukul, Devkee, Serpell, Louise C and Adams, Dave J (2017) Controlling the network type in self-assembled dipeptide hydrogels. Soft Matter, 13 (9). pp. 1914-1919. ISSN 1744-683X
E
Erskine, Elliot, Morris, Ryan J, Schor, Marieke, Earl, Chris, Gillespie, Rachel M C, Bromley, Keith, Sukhodub, Tetyana, Clark, Lauren, Fyfe, Paul, Serpell, Louise C, Stanley-Wall, Nicola R and MacPhee, Cait E (2018) Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA. Molecular Microbiology, 110 (6). pp. 897-913. ISSN 0950-382X
Evans, Simon, Clarke, Devin, Dowell, Nicholas, Tabet, Naji, King - Psychology, Sarah, Hutton, Samuel and Rusted, Jennifer (2018) Using event-related fMRI to examine sustained attention processes and effects of APOE ε4 in young adults. PLoS ONE, 13 (6). e0198312 1-18. ISSN 1932-6203
F
Ford, Lenzie, Crossley, Michael, Vadukul, Devkee M, Kemenes, György and Serpell, Louise C (2017) Structure dependent effects of Amyloid-β on long-term memory in Lymnaea stagnalis. FEBS Letters, 591 (9). pp. 1236-1246. ISSN 0014-5793
G
Gallardo, Rodrigo, Ramakers, Meine, De Smet, Frederik, Claes, Filip, Khodaparast, Ladan, Khodaparast, Laleh, Couceiro, José R, Langenberg, Tobias, Siemons, Maxime, Nyström, Sofie, Young, Laurence J, Laine, Romain F, Young, Lydia, Radaelli, Enrico, Benilova, Iryna, Kumar, Manoj, Staes, An, Desager, Matyas, Beerens, Manu, Vandervoort, Petra, Luttun, Aernout, Gevaert, Kris, Bormans, Guy, Dewerchin, Mieke, Van Eldere, Johan, Carmeliet, Peter, Vande Velde, Greetje, Verfaillie, Catherine, Kaminski, Clemens F, De Strooper, Bart, Hammarström, Per, Nilsson, K Peter R, Serpell, Louise, Schymkowitz, Joost and Rousseau, Frederic (2016) De novo design of a biologically active amyloid. Science, 354 (6313). aah4949. ISSN 0036-8075
H
Hicks, Ben and Innes, Anthea (2020) Developing collaborative relationships with rural-dwelling older men with dementia in the UK: lessons learned from a UK community technological initiative. In: Innes, Anthea, Morgan, Debra and Farmer, Jane (eds.) Remote and rural dementia care: policy, research and practice. Policy Press, Bristol, pp. 151-184. ISBN 9781447344957
Hicks, Ben, Innes, Anthea and Nyman, Samuel R (2019) Experiences of rural life among community-dwelling older men with dementia and their implications for social inclusion. Dementia. pp. 1-20. ISSN 1471-3012
Hoile, Richard, Tabet, Naji, Smith, Helen, Bremner, Stephen, Cassell, Jackie and Ford, Elizabeth (2020) Are symptoms of insomnia in primary care associated with subsequent onset of dementia? A matched retrospective case-control study. Aging and Mental Health, 24 (9). pp. 1466-1471. ISSN 1360-7863
J
John, A, Patel, U, Rusted, J, Richards, M and Gaysina, D (2019) Affective problems and decline in cognitive state in older adults: a systematic review and meta-analysis. Psychological Medicine, 49 (3). pp. 353-365. ISSN 0033-2917
John, Amber, James, Sarah-Naomi, Patel, Urvisha, Rusted, Jennifer, Richards, Marcus and Gaysina, Darya (2019) Longitudinal associations of affective symptoms with mid-life cognitive function: evidence from a British birth cohort. British Journal of Psychiatry, 215 (5). pp. 675-682. ISSN 0007-1250
K
Kraft, Lucas, Serpell, Louise C and Atack, John (2019) A biophysical approach to the identification of novel ApoE chemical probes. Biomolecules, 9 (2). 48 1-16. ISSN 2218-273X
Kubánková, Markéta, López-Duarte, Ismael, Bull, James A, Vadukul, Devkee M, Serpell, Louise C, de Saint Victor, Marie, Stride, Eleanor and Kuimova, Marina K (2017) Probing supramolecular protein assembly using covalently attached fluorescent molecular rotors. Biomaterials, 139. pp. 195-201. ISSN 0142-9612
L
Linke, Reinhold P, Serpell, Louise C, Lottspeich, Friedrich and Toyoda, Mitsuyasu (2017) Cathepsin K as a novel amyloid fibril protein in humans. Amyloid, 24 (1). pp. 68-69. ISSN 1350-6129
M
Maina, Mahmoud B, Bailey, Laura J, Doherty, Aidan J and Serpell, Louise C (2018) The involvement of Aβ42 and tau in nucleolar and protein synthesis machinery dysfunction. Frontiers in Cellular Neuroscience, 12 (220). pp. 1-13. ISSN 1662-5102
Maina, Mahmoud B, Bailey, Laura J, Wagih, Sherin, Biasetti, Luca, Pollack, Saskia J, Quinn, James P, Thorpe, Julian R, Doherty, Aidan J and Serpell, Louise C (2018) The involvement of tau in nucleolar transcription and the stress response. Acta Neuropathologica Communications, 6 (70). pp. 1-13. ISSN 2051-5960
Mangione, P Patrizia, Porcari, Riccardo, Gillmore, Julian D, Pucci, Piero, Monti, Maria, Porcari, Mattia, Giorgetti, Sofia, Marchese, Loredana, Raimondi, Sara, Serpell, Louise C, Chen, Wenjie, Relini, Annalisa, Marcoux, Julien, Clatworthy, Innes R, Taylor, Graham W, Tennent, Glenys A, Robinson, Carol V, Hawkins, Phillip N, Stoppini, Monica, Wood, Stephen P, Pepys, Mark B and Bellotti, Vittorio (2014) Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proceedings of the National Academy of Sciences, 111 (4). pp. 1539-1544. ISSN 0027-8424
Martyr, Anthony, Nelis, Sharon M, Quinn, Catherine, Wu, Yu-Tzu, Lamont, Ruth A, Henderson, Catherine, Clarke, Rachel, Hindle, John V, Thom, Jeanette M, Jones, Ian Rees, Morris, Robin G, Rusted, Jennifer M, Victor, Christina R and Clare, Linda (2018) Living well with dementia: a systematic review and correlational meta-analysis of factors associated with quality of life, well-being and life satisfaction in people with dementia. Psychological Medicine, 48 (13). pp. 2130-2139. ISSN 0033-2917
McAulay, Kate, Dietrich, Bart, Su, Hao, Scott, Michael T., Rogers, Sarah, Al-Hilaly, Youssra K., Cui, Honggang, Serpell, Louise C., Seddon, Annela M., Draper, Emily R. and Adams, Dave J. (2019) Using chirality to influence supramolecular gelation. Chemical Science. ISSN 2041-6539
R
Raulin, Ana-Caroline, Kraft, Lucas, Al-Hilaly, Youssra, Xue, Wei-Feng, McGeehan, John E, Atack, John R and Serpell, Louise (2019) The molecular basis for apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease. Journal of Molecular Biology, 431 (12). pp. 2248-2265. ISSN 0022-2836
S
Sant’Anna, Ricardo, Fernández, Maria Rosario, Batlle, Cristina, Navarro, Susanna, de Groot, Natalia S, Serpell, Louise and Ventura, Salvador (2016) Characterization of amyloid cores in prion domains. Scientific Reports, 6. a34274. ISSN 2045-2322
T
Titheradge, Daniel, Isaac, Mokhtar, Bremner, Stephen and Tabet, Naji (2020) Cambridge Cognitive Examination and Hachinski Ischemic Score as predictors of MRI confirmed pathology in dementia: a cross-sectional study. International Journal of Clinical Practice, 74 (2). pp. 1-10. ISSN 1368-5031
V
Vadukul, Devekee M, Al-Hilaly, Youssra K and Serpell, Louise C (2018) Methods for structural analysis of amyloid fibrils in misfolding diseases. In: Gomes, Cláudio M (ed.) Protein misfolding diseases. Humana Press, New York, NY, pp. 109-122. ISBN 9781493988198
Vadukul, Devkee M, Gbajumo, Oyinkansola, Marshall, Karen E and Serpell, Louise C (2017) Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid-β 1-42. FEBS Letters, 591 (5). pp. 822-830. ISSN 0014-5793