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Treasure, T, Farewell, V, Macbeth, F, Monson, K, Williams, N R, Brew-Graves, C, Lees, B, Grigg, O, Fallowfield, L and PulMiCC Trial Group, . (2019) Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial. Trials, 20 (1). p. 718. ISSN 1745-6215
Bigot, Nicolas, Day, Matthew, Baldock, Robbie A, Watts, Felicity Z, Oliver, Antony W and Pearl, Laurence H (2019) Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. eLIfe, 8. a44353 1-28. ISSN 2050-084X
Benstead-Hume, Graeme, Chen, Xiangrong, Hopkins, Suzi, Lane, Karen A, Downs, Jessica and Pearl, Frances M G (2019) Predicting synthetic lethal interactions using conserved patterns in protein interaction networks. PLoS Computational Biology, 15 (4). e1006888. ISSN 1553-7358
Leimbacher, Pia-Amata, Jones, Samuel E, Shorrocks, Ann-Marie K, de Marco Zompit, Mara, Day, Matthew, Blaauwendraad, Jordy, Bundschuh, Diana, Bonham, Sarah, Fischer, Roman, Fink, Daniel, Kessler, Benedikt M, Oliver, Antony W, Pearl, Laurence H, Blackford, Andrew N and Stucki, Manuel (2019) MDC1 interacts with TOPBP1 to maintain chromosomal stability during mitosis. Molecular Cell. ISSN 1097-2765
Polo, Luis M, Xu, Yingqi, Hornyak, Peter, Garces, Fernando, Zeng, Zhihong, Hailstone, Richard, Matthews, Steve J, Caldecott, Keith W, Oliver, Antony W and Pearl, Laurence H (2019) Efficient single-strand break repair requires binding to both poly(ADP-ribose) and DNA by the central BRCT domain of XRCC1. Cell Reports, 26 (3). 573-581.e5. ISSN 2211-1247
Becker, Jordan R, Cuella-Martin, Raquel, Barazas, Marco, Liu, Rui, Oliveira, Catarina, Oliver, Antony W, Bilham, Kirstin, Holt, Abbey B, Blackford, Andrew N, Heierhorst, Jörg, Jonkers, Jos, Rottenberg, Sven and Chapman, J Ross (2018) The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity. Nature communications, 9 (5406). pp. 1-12. ISSN 2041-1723
Rata, Scott, Suarez Peredo Rodriguez, Maria F, Joseph, Stephy, Peter, Nisha, Echegaray Iturra, Fabio, Yang, Fengwei, Madzvamuse, Anotida, Ruppert, Jan G, Samejima, Kumiko, Platani, Melpomeni, Alvarez-Fernandez, Monica, Malumbres, Marcos, Earnshaw, William C, Novak, Bela and Hochegger, Helfrid (2018) Two interlinked bistable switches govern mitotic control in mammalian cells. Current Biology, 28 (23). 3824-3832.e6. ISSN 0960-9822
Day, Matthew, Rappas, Mathieu, Ptasinska, Katie, Boos, Dominik, Oliver, Antony W and Pearl, Laurence H (2018) BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands. eLife, 7 (e39979). pp. 1-18. ISSN 2050-084X
Zagnol-iVieira, Guido, Bruni, Francesco, Thompson, Kyle, He, Langping, Walker, Sarah, de Brouwer, Arjan P M, Taylor, Robert, Niyazov, Dimitriy and Caldecott, Keith W (2018) Confirming TDP2 mutation in spinocerebellar ataxia autosomal recessive 23 (SCAR23). Neurology Genetics, 4 (4). ISSN 2376-7839
Hanzlikova, Hana, Kalasova, Ilona, Demin, Annie A, Pennicott, Lewis E, Cihlarova, Zuzana and Caldecott, Keith W (2018) The importance of Poly(ADP-Ribose) Polymerase as a sensor of unligated Okazaki fragments during DNA replication. Molecular Cell, 71 (2). pp. 319-331. ISSN 1097-2765
Lemmens, Bennie, Hegarat, Nadia, Akopyan, Karen, Sala-Gaston, Joan, Bartek, Jiri, Hochegger, Helfrid and Lindqvist, Arne (2018) DNA replication determines timing of mitosis by restricting CDK1 and PLK1 activation. Molecular Cell, 71 (1). 117-128.e3. ISSN 1097-2765
Gómez-Herreros, Fernando, Zagnoli-Vieira, Guido, Ntai, Ioanna, Martínez-Macías, María Isabel, Anderson, Rhona M, Herrero-Ruíz, Andrés and Caldecott, Keith W (2017) TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription. Nature Communications, 8 (1). a233 1-9. ISSN 2041-1723
Ocasio, Tony, Sansook, Supojjanee, Jones, Alice Rhiannon, Roberts, Justin, Scott, Thomas, Tsoureas, Nikolaos, Coxhead, Peter, Guille, Matthew, Tizzard, Graham J, Coles, Simon J, Hochegger, Helfrid, Bradner, James E and Spencer, John (2017) Pojamide: An HDAC3-selective ferrocene analogue with remarkably enhanced redox-triggered ferrocenium activity in cells. Organometallics, 36 (17). pp. 3276-3283. ISSN 0276-7333
Monson, Kathryn, Treasure, Tom, Brew-Graves, Chris, Jenkins, Valerie and Fallowfield, Lesley (2017) [Abstract] Surveying patients’ views on trial information provision and decision making using the ‘Accept/Decline’ clinical trials questionnaire. Trials, 18 (Suppl1). P61. ISSN 1745-6215
Grassano, Nicola, Rotolo, Daniele, Hutton, Joshua, Lang, Frédérique and Hopkins, Michael M (2017) Funding data from publication acknowledgements: coverage, uses and limitations. Journal of the Association for Information Science and Technology, 68 (4). pp. 999-1017. ISSN 2330-1643
Rulten, Stuart and Caldecott, Keith (2016) The PARP inhibitor AZD2461 provides insights into the role of PARP3 inhibition for both synthetic lethality and tolerability with chemotherapy in preclinical models. Cancer Research, 76 (20). ISSN 0008-5472
Grundy, Gabrielle J, Rulten, Stuart L, Arribas-Bosacoma, Raquel, Davidson, Kathryn, Kozik, Zuzanna, Oliver, Antony W, Pearl, Laurence H and Caldecott, Keith W (2016) The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins. Nature Communications, 7 (1). a11242. ISSN 2041-1723
Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W and Oliver, Antony W (2016) Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal, 473 (13). pp. 1869-1879. ISSN 0264-6021
Dai, Xiaoxia, Rulten, Stuart L, You, Changjun, Caldecott, Keith W and Wang, Yinsheng (2015) Identification and functional characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in human Poly(ADP-ribose) Polymerase 3. Journal of proteome research, 14 (6). pp. 2575-2582. ISSN 1535-3907
Mohebi, Saed, Mizuno, Ken'Ichi, Watson, Adam, Carr, Antony M and Murray, Johanne M (2015) Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements. Nature Communications, 6 (1). a6357. ISSN 2041-1723
Jenkins, Valerie and Fallowfield, Lesley (2015) For the benefit of others: reasons why women with breast cancer participate in RCTs. Breast Care, 10 (2). ISSN 1661-3805
Cooley, Carol, Dave, Anoushka, Garg, Mansi and Bianchi, Alessandro (2014) Tel1ATM dictates the replication timing of short yeast telomeres. EMBO Reports, 15 (10). pp. 1093-1101. ISSN 1469-221X
Kustatscher, Georg, Hégarat, Nadia, Willis, Karen L H, Furlan, Cristina, Bukowski-Wills, Jimi-Carlo, Hochegger, Helfrid and Rappsilber, Juri (2014) Proteomics of a fuzzy organelle: interphase chromatin. The EMBO Journal, 33 (6). pp. 648-664. ISSN 0261-4189
Hegarat, Nadia, Vesely, Clare, Peter, Nisha, Oliver, Antony and Hochegger, Helfrid (2014) PP2A/B55 and Fcp1 regulate Greatwall and Ensa desphorylation during mitotic exit. PLoS Genetics, 10 (2). e1004259 1. ISSN 1553-7390
Catt, Susan, Chalmers, Anthony, Critchley, Giles and Fallowfield, Lesley (2012) Supportive follow-up in patients treated with radical intent for high-grade glioma. CNS Oncology, 1 (1). pp. 39-48. ISSN 2045-0907