Day, Matthew, Oliver, Antony W and Pearl, Laurence H (2021) Phosphorylation-dependent assembly of DNA damage response systems and the central roles of TOPBP1. DNA Repair, 108. a103232 1-11. ISSN 1568-7864

Prabhakar, Apurva T, James, Claire D, Das, Dipon, Otoa, Raymonde, Day, Matthew, Burgner, John, Fontan, Christian T, Wang, Xu, Glass, Sarah H, Wieland, Andreas, Donaldson, Mary M, Bristol, Molly L, Li, Renfeng, Oliver, Antony W, Pearl, Laurence H, Smith, Brian O and Morgana, Iain M (2021) CK2 phosphorylation of human papillomavirus 16 E2 on serine 23 promotes interaction with TopBP1 and Is critical for E2 interaction with mitotic chromatin and the viral life cycle. mBio, 12 (5). pp. 1-23. ISSN 2150-7511

Wu, Wei, Hill, Sarah E, Nathan, William J, Paiano, Jacob, Callen, Elsa, Wang, Dongpeng, Shinoda, Kenta, van Wietmarschen, Niek, Colón-Mercado, Jennifer M, Zong, Dali, De Pace, Raffaella, Shih, Han-Yu, Coon, Steve, Hanzlikova, Hana, Caldecott, Keith W and others, (2021) Neuronal enhancers are hotspots for DNA single-strand break repair. Nature, 593. pp. 440-444. ISSN 0028-0836

Chen, Xiangrong, Ali, Yusuf I, Fisher, Charlotte E L, Arribas-Bosacoma, Raquel, Rajasekaran, Mohan B, Williams, Gareth, Walker, Sarah, Booth, Jessica R, Hudson, Jessica J R, Roe, S Mark, Pearl, Laurence H, Ward, Simon E, Pearl, Frances M G and Oliver, Antony W (2021) Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein. eLife, 10. a65339 1-32. ISSN 2050-084X

Treasure, T, Farewell, V, Macbeth, F, Monson, K, Williams, N R, Brew-Graves, C, Lees, B, Grigg, O, Fallowfield, L and PulMiCC Trial Group, . (2019) Pulmonary metastasectomy versus continued active monitoring in colorectal cancer (PulMiCC): a multicentre randomised clinical trial. Trials, 20 (1). p. 718. ISSN 1745-6215

Bigot, Nicolas, Day, Matthew, Baldock, Robbie A, Watts, Felicity Z, Oliver, Antony W and Pearl, Laurence H (2019) Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. eLIfe, 8. a44353 1-28. ISSN 2050-084X

Benstead-Hume, Graeme, Chen, Xiangrong, Hopkins, Suzi, Lane, Karen A, Downs, Jessica and Pearl, Frances M G (2019) Predicting synthetic lethal interactions using conserved patterns in protein interaction networks. PLoS Computational Biology, 15 (4). e1006888. ISSN 1553-7358

Leimbacher, Pia-Amata, Jones, Samuel E, Shorrocks, Ann-Marie K, de Marco Zompit, Mara, Day, Matthew, Blaauwendraad, Jordy, Bundschuh, Diana, Bonham, Sarah, Fischer, Roman, Fink, Daniel, Kessler, Benedikt M, Oliver, Antony W, Pearl, Laurence H, Blackford, Andrew N and Stucki, Manuel (2019) MDC1 interacts with TOPBP1 to maintain chromosomal stability during mitosis. Molecular Cell. ISSN 1097-2765

Polo, Luis M, Xu, Yingqi, Hornyak, Peter, Garces, Fernando, Zeng, Zhihong, Hailstone, Richard, Matthews, Steve J, Caldecott, Keith W, Oliver, Antony W and Pearl, Laurence H (2019) Efficient single-strand break repair requires binding to both poly(ADP-ribose) and DNA by the central BRCT domain of XRCC1. Cell Reports, 26 (3). 573-581.e5. ISSN 2211-1247

Becker, Jordan R, Cuella-Martin, Raquel, Barazas, Marco, Liu, Rui, Oliveira, Catarina, Oliver, Antony W, Bilham, Kirstin, Holt, Abbey B, Blackford, Andrew N, Heierhorst, Jörg, Jonkers, Jos, Rottenberg, Sven and Chapman, J Ross (2018) The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity. Nature Communications, 9 (5406). pp. 1-12. ISSN 2041-1723

Rata, Scott, Suarez Peredo Rodriguez, Maria F, Joseph, Stephy, Peter, Nisha, Echegaray Iturra, Fabio, Yang, Fengwei, Madzvamuse, Anotida, Ruppert, Jan G, Samejima, Kumiko, Platani, Melpomeni, Alvarez-Fernandez, Monica, Malumbres, Marcos, Earnshaw, William C, Novak, Bela and Hochegger, Helfrid (2018) Two interlinked bistable switches govern mitotic control in mammalian cells. Current Biology, 28 (23). 3824-3832.e6. ISSN 0960-9822

Day, Matthew, Rappas, Mathieu, Ptasinska, Katie, Boos, Dominik, Oliver, Antony W and Pearl, Laurence H (2018) BRCT domains of the DNA damage checkpoint proteins TOPBP1/Rad4 display distinct specificities for phosphopeptide ligands. eLife, 7 (e39979). pp. 1-18. ISSN 2050-084X

Zagnol-iVieira, Guido, Bruni, Francesco, Thompson, Kyle, He, Langping, Walker, Sarah, de Brouwer, Arjan P M, Taylor, Robert, Niyazov, Dimitriy and Caldecott, Keith W (2018) Confirming TDP2 mutation in spinocerebellar ataxia autosomal recessive 23 (SCAR23). Neurology Genetics, 4 (4). ISSN 2376-7839

Hanzlikova, Hana, Kalasova, Ilona, Demin, Annie A, Pennicott, Lewis E, Cihlarova, Zuzana and Caldecott, Keith W (2018) The importance of Poly(ADP-Ribose) Polymerase as a sensor of unligated Okazaki fragments during DNA replication. Molecular Cell, 71 (2). pp. 319-331. ISSN 1097-2765

Lemmens, Bennie, Hegarat, Nadia, Akopyan, Karen, Sala-Gaston, Joan, Bartek, Jiri, Hochegger, Helfrid and Lindqvist, Arne (2018) DNA replication determines timing of mitosis by restricting CDK1 and PLK1 activation. Molecular Cell, 71 (1). 117-128.e3. ISSN 1097-2765

Robinson, Sophie R, Viegas, Sandra C, Matos, Rute G, Domingues, Susana, Bedir, Marisa, Stewart, Helen J S, Chevassut, Timothy, Oliver, Antony W, Arraiano, Cecilia M and Newbury, Sarah F (2018) DIS3 isoforms vary in their endoribonuclease activity and are differentially expressed within haematological cancers. Biochemical Journal, 475 (12). pp. 2091-2105. ISSN 0264-6021

Mok, Myth T, Zhou, Jingying, Tang, Wenshu, Zeng, Xuezhen, Oliver, Antony W, Ward, Simon E and Cheng, Alfred S L (2018) CCRK is a novel signalling hub exploitable in cancer immunotherapy. Pharmacology and Therapeutics, 186. pp. 138-151. ISSN 0163-7258

Gómez-Herreros, Fernando, Zagnoli-Vieira, Guido, Ntai, Ioanna, Martínez-Macías, María Isabel, Anderson, Rhona M, Herrero-Ruíz, Andrés and Caldecott, Keith W (2017) TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription. Nature Communications, 8 (1). a233 1-9. ISSN 2041-1723

Ocasio, Tony, Sansook, Supojjanee, Jones, Alice Rhiannon, Roberts, Justin, Scott, Thomas, Tsoureas, Nikolaos, Coxhead, Peter, Guille, Matthew, Tizzard, Graham J, Coles, Simon J, Hochegger, Helfrid, Bradner, James E and Spencer, John (2017) Pojamide: An HDAC3-selective ferrocene analogue with remarkably enhanced redox-triggered ferrocenium activity in cells. Organometallics, 36 (17). pp. 3276-3283. ISSN 0276-7333

Monson, Kathryn, Treasure, Tom, Brew-Graves, Chris, Jenkins, Valerie and Fallowfield, Lesley (2017) [Abstract] Surveying patients’ views on trial information provision and decision making using the ‘Accept/Decline’ clinical trials questionnaire. Trials, 18 (Suppl1). a200 P61. ISSN 1745-6215

Grassano, Nicola, Rotolo, Daniele, Hutton, Joshua, Lang, Frédérique and Hopkins, Michael M (2017) Funding data from publication acknowledgements: coverage, uses and limitations. Journal of the Association for Information Science and Technology, 68 (4). pp. 999-1017. ISSN 2330-1643

Rulten, Stuart and Caldecott, Keith (2016) The PARP inhibitor AZD2461 provides insights into the role of PARP3 inhibition for both synthetic lethality and tolerability with chemotherapy in preclinical models. Cancer Research, 76 (20). ISSN 0008-5472

Grundy, Gabrielle J, Rulten, Stuart L, Arribas-Bosacoma, Raquel, Davidson, Kathryn, Kozik, Zuzanna, Oliver, Antony W, Pearl, Laurence H and Caldecott, Keith W (2016) The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins. Nature Communications, 7 (1). a11242. ISSN 2041-1723

Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W and Oliver, Antony W (2016) Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal, 473 (13). pp. 1869-1879. ISSN 0264-6021

Dai, Xiaoxia, Rulten, Stuart L, You, Changjun, Caldecott, Keith W and Wang, Yinsheng (2015) Identification and functional characterizations of N-Terminal α-N-Methylation and Phosphorylation of Serine 461 in human Poly(ADP-ribose) Polymerase 3. Journal of proteome research, 14 (6). pp. 2575-2582. ISSN 1535-3907

Mohebi, Saed, Mizuno, Ken'Ichi, Watson, Adam, Carr, Antony M and Murray, Johanne M (2015) Checkpoints are blind to replication restart and recombination intermediates that result in gross chromosomal rearrangements. Nature Communications, 6 (1). a6357. ISSN 2041-1723

Jenkins, Valerie and Fallowfield, Lesley (2015) For the benefit of others: reasons why women with breast cancer participate in RCTs. Breast Care, 10 (2). ISSN 1661-3805

Cooley, Carol, Dave, Anoushka, Garg, Mansi and Bianchi, Alessandro (2014) Tel1ATM dictates the replication timing of short yeast telomeres. EMBO Reports, 15 (10). pp. 1093-1101. ISSN 1469-221X

Kustatscher, Georg, Hégarat, Nadia, Willis, Karen L H, Furlan, Cristina, Bukowski-Wills, Jimi-Carlo, Hochegger, Helfrid and Rappsilber, Juri (2014) Proteomics of a fuzzy organelle: interphase chromatin. The EMBO Journal, 33 (6). pp. 648-664. ISSN 0261-4189

Hegarat, Nadia, Vesely, Clare, Peter, Nisha, Oliver, Antony and Hochegger, Helfrid (2014) PP2A/B55 and Fcp1 regulate Greatwall and Ensa desphorylation during mitotic exit. PLoS Genetics, 10 (2). e1004259 1. ISSN 1553-7390

Catt, Susan, Chalmers, Anthony, Critchley, Giles and Fallowfield, Lesley (2012) Supportive follow-up in patients treated with radical intent for high-grade glioma. CNS Oncology, 1 (1). pp. 39-48. ISSN 2045-0907