A

Al-Shahi Salman, Rustam, Dennis, Martin S, Sandercock, Peter A G, Sudlow, Cathie L M, Wardlaw, Joanna M, Whiteley, William N, Murray, Gordon D, Stephen, Jacqueline, Rodriguez, Aryelly, Lewis, Steff, Werring, David J, White, Phil M, RESTART Collaboration, and Rajkumar, Chakravarthi (2021) Effects of antiplatelet therapy after stroke caused by intracerebral hemorrhage: extended follow-up of the RESTART randomized clinical trial. JAMA Neurology, 78 (10). pp. 1179-1186. ISSN 2168-6149

Alsagaby, Suliman A, Brewis, Ian A, Vijayakumar, Rejendran, Alhumaydhi, Fahad A, Alwashmi, Ameen S, Alharbi, Naif K, Al Abdulmonem, Waleed, Premanathan, Mariappan, Pratt, Guy, Fegan, Christopher, Pepper, Christopher and Brennan, Paul (2021) Proteomics-based identification of cancer-associated proteins in chronic lymphocytic leukaemia. Electronic Journal of Biotechnology, 52. pp. 1-12. ISSN 0717-3458

Alves, Mariana, Fernandes, Marília Andreia, Bahat, Gülistan, Benetos, Athanase, Clemente, Hugo, Grodzicki, Tomasz, Martínez-Sellés, Manuel, Mattace-Raso, Francesco, Rajkumar, Chakravarthi, Ungar, Andrea, Werner, Nikos, Strandberg, Timo E, EuGMS Special Interest Group inCardiovascular Medicine, and Unset (2021) Protecting older patients with cardiovascular diseases from COVID-19 complications using current medications. European Geriatric Medicine, 12 (4). pp. 725-739. ISSN 1878-7649

Arabi, Yaseen M, Gordon, Anthony C, Derde, Lennie P G, Nichol, Alistair D, Murthy, Srinivas, Beidh, Farah Al, Annane, Djillali, Swaidan, Lolowa Al, Beane, Abi, Beasley, Richard, Berry, Lindsay R, Bhimani, Zahra, Bonten, Marc J M, Bradbury, Charlotte A and Phillips, Barbara (2021) Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. Intensive Care Medicine, 47. pp. 867-886. ISSN 0342-4642

B

Barrett, Thomas J, Patterson, Karen C, James, Timothy M and Kruger, Peter (2021) Impact of reduction of susceptibility to SARS-CoV-2 on epidemic dynamics in four early-seeded metropolitan regions. Scientific Reports, 11 (1). a12213 1-11. ISSN 2045-2322

Battisti, Nicolo` Matteo Luca, Reed, Malcolm W R, Herbert, Esther, Morgan, Jenna L, Collins, Karen A, Ward, Sue E, Holmes, Geoffrey R, Bradburn, Michael, Walters, Stephen J, Burton, Maria, Lifford, Kate, Edwards, Adrian, Robinson, Thompson G, Martin, Charlene, Wright, Juliet and others, (2021) Bridging the age gap in breast cancer: impact of chemotherapy on quality of life in older women with early breast cancer. European Journal of Cancer, 144. pp. 269-280. ISSN 0959-8049

Battisti, Nicolò Matteo Luca, Hatton, Matthew Q, Reed, Malcolm W R, Herbert, Esther, Morgan, Jenna L, Bradburn, Michael, Simcock, Richard, Walters, Stephen J, Collins, Karen A, Ward, Sue E, Holmes, Geoffrey R, Burton, Maria, Lifford, Kate J, Edwards, Adrian, Wright, Juliet and others, (2021) Observational cohort study in older women with early breast cancer: use of radiation therapy and impact on health-related quality of life and mortality. Radiotherapy and Oncology, 161. pp. 166-176. ISSN 0167-8140

Bomben, Riccardo, Rossi, Francesca Maria, Vit, Filippo, Bittolo, Tamara, D'Agaro, Tiziana, Zucchetto, Antonella, Tissino, Erika, Pozzo, Federico, Vendramini, Elena, Degan, Massimo, Zaina, Eva, Cattarossi, Ilaria, Varaschin, Paola, Nanni, Paola, Pepper, Chris and others, (2021) TP53 mutations with low variant allele frequency predict short survival in chronic lymphocytic leukemia. Clinical Cancer Research, 27 (20). pp. 5566-5575. ISSN 1078-0432

Botham, Jed, Shilling, Valerie and Jones, John (2021) Patient and public understanding of the concept of ‘personalised medicine’ in relation to cancer treatment: a systematic review. Future Healthcare Journal, 8 (3). e703-e708. ISSN 2514-6645

Bruce, Julie, Mazuquin, Bruno, Canaway, Alastair, Hossain, Anower, Williamson, Esther, Mistry, Pankaj, Lall, Ranjit, Petrou, Stavros, Lamb, Sarah E, Rees, Sophie, Padfield, Emma, Vidya, Raghavan, Thompson, Alastair M, Prevention of Shoulder Problems Trial (PROSPER) Study Group, and Reed, Malcolm (2021) Exercise versus usual care after non-reconstructive breast cancer surgery (UK PROSPER): multicentre randomised controlled trial and economic evaluation. British Medical Journal, 375. a066542 1-11. ISSN 1759-2151

Bruno, Rosa M, Spronck, Bart, Hametner, Bernhard, Hughes, Alun, Lacolley, Patrick, Mayer, Christopher C, Muiesan, Maria L, Rajkumar, Chakravarthi, Terentes-Printzios, Dimitrios, Weber, Thomas, Hansen, Tine W, Boutouyrie, Pierre and ARTERY Society, (2021) Covid-19 effects on ARTErial StIffness and vascular AgeiNg: CARTESIAN study rationale and protocol. Artery Research, 27 (2). pp. 59-68. ISSN 1872-9312

Burton, Maria, Lifford, Kate J, Wyld, Lynda, Armitage, Fiona, Ring, Alistair, Nettleship, Anthony, Collins, Karen, Morgan, Jenna, Reed, Malcolm W R, Holmes, Geoffrey R, Bradburn, Mike, Gath, Jacqui, Green, Tracy, Revell, Deidre, Brain, Kate and Edwards, Adrian (2021) Process evaluation of the Bridging the Age Gap in Breast Cancer decision support intervention cluster randomised trial. Trials, 22 (a447). pp. 1-13. ISSN 1745-6215

C

Casarotti, Ana C A, Teixeira, Daniela, Longo-Maugeri, Ieda M, Ishimura, Mayari E, Coste, Maria E R, Bianco, Henrique T, Moreira, Flavio T, Bacchin, Amanda F, Izar, Maria C, Gonçalves, Iran, Caixeta, Adriano, Szarf, Gilberto, Pinto, Ibraim M and Fonseca, Francisco A (2021) Role of B lymphocytes in the infarcted mass in patients with acute myocardial infarction. Bioscience Reports, 41 (2). BSR20203413. ISSN 0144-8463

Caserta, Stefano and Ghezzi, Pietro (2021) Release of redox enzymes and micro-RNAs in extracellular vesicles, during infection and inflammation. Free Radical Biology and Medicine. ISSN 0891-5849

Ceeraz, Sabrina, Thompson, Charlotte R, Beatson, Richard and Choy, Ernest H (2021) Harnessing cd8⁺cd28⁻ regulatory t cells as a tool to treat autoimmune disease. Cells, 10 (11). a2973 1-11. ISSN 2073-4409

Chang, Yu-Ling, Rossetti, Maura, Gjertson, David W, Rubbi, Liudmilla, Thompson, Michael, Montoya, Dennis J, Morselli, Marco, Ruffin, Felicia, Hoffmann, Alexander, Pellegrini, Matteo, Fowler, Vance G, Yeaman, Michael R, Reed, Elaine F, Mitchell, Simon, the MRSA Systems Immunology Group, and others, (2021) Human DNA methylation signatures differentiate persistent from resolving MRSA bacteremia. Proceedings of the National Academy of Sciences (PNAS), 118 (10). a2000663118 1-11. ISSN 0027-8424

Chevassut, Tim, Hunt, Beverley J and Pavord, Sue (2021) VITT, COVID-19 and the Expert Haematology Panel: the story of how the UK responded to emerging cases of vaccine-induced immune thrombocytopenia and thrombosis during the vaccination programme. Clinical Medicine, 21 (6). pp. 1-3. ISSN 1470-2118

Clanchy, Felix I L, Borghese, Federica, Bystrom, Jonas, Balog, Attilia, Penn, Henry, Hull, Dobrina N, Wells, Graham M A, Kiriakidis, Serafim, Taylor, Peter C, Sacre, Sandra M, Williams, Lynn M, Stone, Trevor W, Mageed, Rizgar A and Williams, Richard O (2021) TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis. Journal of Autoimmunity, 118. a102597 1-10. ISSN 0896-8411

Cooke, Graham S, Pett, Sarah, McCabe, Leanne, Jones, Chris, Gilson, Richard, Verma, Sumita, Ryder, Stephen D, Collier, Jane D, Barclay, Stephen T, Ala, Aftab, Bhagani, Sanjay, Nelson, Mark, Ch'Ng, Chinlye, Stone, Ben, Wiselka, Martin and others, (2021) Strategic treatment optimization for HCV (STOPHCV1): a randomised controlled trial of ultrashort duration therapy for chronic hepatitis C. Wellcome Open Research, 6 (a93). pp. 1-29. ISSN 2398-502X

Cooper, Max, Pollard, Alex, Panday, Aparjita, Bremner, Stephen, Macken, Lucia, Evans, Catherine J, Austin, Mark, Parnell, Nick, Steer, Shani, Thomson, Sam, Hashim, Ahmed, Mason, Louise and Verma, Sumita (2021) Palliative long-term abdominal drains versus large volume paracentesis in refractory ascites due to cirrhosis (REDUCe study): qualitative outcomes. Journal of Pain and Symptom Management, 62 (2). 312-325.e2. ISSN 0885-3924

D

Dare, Samuel S, Merlo, Emiliano, Rodriguez Curt, Jesus, Ekanem, Peter E, Hu, Nan and Berni, Jimena (2021) Drosophila para^bss flies as a screening model for traditional medicine: anticonvulsant effects of Annona senegalensis. Frontiers in Neurology, 11. a606919 1-14. ISSN 1664-2295

Daultrey, Harriet, Youseff, Elaney, Wright, Juliet, Davies, Kevin, Chakera, Ali J and Levett, Tom (2021) The investigation of diabetes in people living with HIV: a systematic review. Diabetic Medicine, 38 (4). a14454 1-11. ISSN 0742-3071

Dore, Henry, Aviles-Espinosa, Rodrigo, Luo, Zhenhua, Anton, Oana, Rabe, Heike and Rendon-Morales, Elizabeth (2021) Characterisation of textile embedded electrodes for use in a neonatal smart mattress electrocardiography system. Sensors, 21 (3). a999 1-20. ISSN 1424-8220

de Belder, Adam, Myat, Aung, Blaxill, Jonathan, Haworth, Peter, O’Kane, Peter, Hatrick, Robert, Aggarwal, Rajesh, Davie, Andrew, Smith, William, Gerber, Robert, Byrne, Jonathan, Adamson, Dawn, Witherow, Fraser, Alsanjari, Osama, Wright, Juliet, Robinson, Derek R and Hildick-Smith, David (2021) Revascularisation or medical therapy in elderly patients with acute anginal syndromes (RINCAL) a randomised trial. EuroIntervention, 17 (1). pp. 67-74. ISSN 1969-6213

E

Eccles, Jessica, Thompson, Beth, Themelis, Kristy, Amato, Marisa L, Stocks, Robyn, Pound, Amy, Jones, Anna-Marie, Cipinova, Zdenka, Shah-Goodwin, Lorraine, Timeyin, Jean, Thompson, Charlotte R, Batty, Thomas, Harrison, Neil A, Critchley, Hugo D and Davies, Kevin A (2021) Beyond bones: the relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study. Clinical Medicine, 21 (1). pp. 53-58. ISSN 1470-2118

Emerson, Alexander G and Kloepfer, Kirsten M (2021) A genome-wide association study of severe asthma exacerbations in Latino children and adolescents. Pediatrics, 148 (Sup3). S54-S54. ISSN 0031-4005

Evans, Catherine J, Bone, Anna E, Yi, Deokhee, Gao, Wei, Morgan, Myfanwy, Taherzadeh, Shamim, Maddocks, Matthew, Wright, Juliet, Lindsay, Fiona, Bruni, Carla, Harding, Richard, Sleeman, Katherine E, Gomes, Barbara and Higgingson, Irene J (2021) Community-based short-term integrated palliative and supportive care reduces symptom distress for older people with noncancer conditions compared with usual care: a randomised controlled single-blind mixed method trial. International Journal of Nursing Studies, 120. a103978 1-13. ISSN 0020-7489

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Ferretti, Agata, Ienca, Marcello, Sheehan, Mark, Blasimme, Alessandro, Dove, Edward S, Farsides, Bobbie, Friesen, Phoebe, Kahn, Jeff, Karlen, Walter, Kleist, Peter, Liao, S Matthew, Nebeker, Camille, Samuel, Gabrielle, Shabani, Mahsa, Rivas Velarde, Minerva and Vayena, Effy (2021) Ethics review of big data research: what should stay and what should be reformed? BMC Medical Ethics, 22 (1). a51 1-13. ISSN 1472-6939

Fidler, Katy, Dudley, Julia, Cloke, Rachel, Nicholls, Margot, Greig, David R, Dallman, Timothy J, Chattaway, Marie Anne and Godbole, Gauri (2021) Salmonella Paratyphi B; public health and parental choice: when to treat asymptomatic carriers of infection? Pediatric Infectious Disease Journal, 40 (10). e374-e378. ISSN 0891-3668

Fish, Max, Shahvisi, Arianne, Gwaambuka, Tatenda, Tangwa, Godfrey B, Ncayiyana, Daniel and Earp, Brian D (2021) Voluntary medical male circumcision: responding to Brian Morris. Clinical Infectious Diseases, 73 (11). p. 2152. ISSN 1058-4838

G

Ghezzi, Pietro (2021) Redox regulation of immunity and the role of small molecular weight thiols. Redox Biology. a102001. ISSN 2213-2317

Gliddon, Harriet D, Kaforou, Myrsini, Alikian, Mary, Habgood-Coote, Dominic, Zhou, Chenxi, Oni, Tolu, Anderson, Suzanne T, Brent, Andrew J, Crampin, Amelia C, Eley, Brian, Heyderman, Robert, Kern, Florian, Langford, Paul R, Ottenhoff, Tom H M, Hibberd, Martin L and others, (2021) Identification of reduced host transcriptomic signatures for tuberculosis disease and digital PCR-based validation and quantification. Frontiers in Immunology, 12. a637164 1-13. ISSN 1664-3224

Gordon, A C, Mouncey, P R, Al-Beidh, F, Rowan, K M, Nichol, A D, Arabi, Y M, Annane, D, Beane, A, van Bentum-Puijk, W, Berry, L R, Bhimani, Z, Bonten, M J M, Bradbury, C A, Brunkhorst, F M, Phillips, B, REMAP-CAP investigators and collaborators, and others, (2021) Interleukin-6 receptor antagonists in critically ill patients with Covid-19. New England Journal of Medicine, 384 (16). pp. 1491-1502. ISSN 0028-4793

Graham, Charlotte Elizabeth, Jozwik, Agnieszka, Quartey-Papafio, Ruby, Ioannou, Nikolaos, Metelo, Ana M, Scala, Carlo, Dickson, Glenda, Stewart, Orla, Almena-Carrasco, Maria, Peranzoni, Elisa, Ramsay, Alan G, Patten, Piers E M, Pertel, Thomas, Farzaneh, Farzin, Dupouy, Sandra, Pepper, Andrea and Benjamin, Reuben (2021) Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma. Leukemia. pp. 1-4. ISSN 0887-6924

H

Harris, H, Bhutta, M F and Rizan, C (2021) A survey of UK and Irish surgeons' attitudes, behaviours and barriers to change for environmental sustainability. Annals of the Royal College of Surgeons of England, 103 (10). pp. 725-729. ISSN 0035-8843

Hashim, A, Macken, L, Jones, A M, McGeer, M, Aithal, G P and Verma, S (2021) Community-based assessment and treatment of Hepatitis C virus-related liver disease, injecting drug and alcohol use amongst people who are homeless: a systematic review and meta-analysis. International Journal of Drug Policy. a103342. ISSN 0955-3959

Hassell-Hart, Storm, Picaud, Sarah, Lengacher, Raphael, Csucker, Joshua, Millet, Regis, Gasser, Gilles, Alberto, Roger, Maple, Hannah, Felix, Robert, Leśnikowski, Zbigniew J, Stewart, Helen J S, Chevassut, Timothy J, Morley, Simon, Filippakopoulos, Panagis and Spencer, John (2021) Probing BRD inhibition substituent effects in bulky analogues of (+)-JQ1. Helvetica Chimica Acta, 104 (3). a2000214 1-7. ISSN 0018-019X

Hernandez-Pacheco, Natalia, Gorenjak, Mario, Li, Jiang, Repnik, Katja, Vijverberg, Susanne J, Berce, Vojko, Jorgensen, Andrea, Karimi, Leila, Schieck, Maximilian, Samedy-Bates, Lesly-Anne, Tavendale, Roger, Villar, Jesús, Mukhopadhyay, Somnath, Pirmohamed, Munir, Verhamme, Katia M C and others, (2021) Identification of ROBO2 as a potential locus associated with inhaled corticosteroid response in childhood asthma. Journal of personalised medicine, 11 (8). a733 1-17. ISSN 2075-4426

Hernandez-Pacheco, Natalia, Vijverberg, Susanne J, Herrera-Luis, Esther, Li, Jiang, Sio, Yang Yie, Granell, Raquel, Corrales, Almudena, Maroteau, Cyrielle, Lethem, Ryan, Perez-Garcia, Javier, Farzan, Niloufar, Repnik, Katja, Gorenjak, Mario, Soares, Patricia, Mukhopadhyay, Somnath, PiCA and SysPharmPedia consortia, and others, (2021) Genome-wide association study of asthma exacerbations despite inhaled corticosteroids use. European Respiratory Journal, 57 (1). pp. 1-93. ISSN 0903-1936

Holenya, Pavlo, Lange, Paul Joris, Reimer, Ulf, Woltersdorf, Wolfram, Panterodt, Thomas, Glas, Michael, Wasner, Mark, Eckey, Maren, Drosch, Michael, Hollidt, Jörg‐Michael, Naumann, Michael, Kern, Florian, Wenschuh, Holger, Lange, Robert, Schnatbaum, Karsten and Bier, Frank F (2021) Peptide microarray based analysis of antibody responses to SARS-CoV-2 identifies unique epitopes with potential for diagnostic test development. European Journal of Immunology. ISSN 0014-2980

Holmes, Geoffrey R, Ward, Sue E, Brennan, Alan, Bradburn, Michael, Morgan, Jenna L, Reed, Malcolm W R, Richards, Paul, Rafia, Rachid, Wyld, Lynda and The Age Gap Trial Steering Group, (2021) Cost-effectiveness modeling of surgery plus adjuvant endocrine therapy versus primary endocrine therapy alone in UK women aged 70 and over with early breast cancer. Value in Health, 24 (6). pp. 770-779. ISSN 1098-3015

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Jayawant, Eleanor S, Hutchinson, Jack, Gašparíková, Dorota, Lockey, Christine, Pruñonosa Lara, Lidón, Guy, Ciaran, Brooks, Rhiannon L and Dixon, Ann M (2021) Molecular basis of selectivity and activity for the antimicrobial Peptide Lynronne-1 informs rational design of Peptide with improved activity. ChemBioChem, 22 (14). pp. 2430-2439. ISSN 1439-4227

Jones, J R, Barber, A, Le Bihan, Y V, Weinhold, N, Ashby, C, Walker, B A, Wardell, C P, Wang, H, Kaiser, M F, Jackson, G H, Davies, F E, Chopra, R, Morgan, G J and Pawlyn, C (2021) Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs. Leukemia, 35. pp. 3017-3020. ISSN 0887-6924

Jones, John, Jackson, Graham and Pawlyn, Jones (2021) Safety of lenalidomide for maintenance treatment of patients with multiple myeloma following autologous stem cell transplantation. Expert Opinion on Drug Safety. ISSN 1474-0338

K

Karimi, Leila, Vijverberg, Susanne J, Engelkes, Marjolein, Hernandez-Pacheco, Natalia, Farzan, Niloufar, Soares, Patricia, Pino-Yanes, Maria, Jorgensen, Andrea L, Eng, Celeste, Mukhopadhyay, Somnath, PiCA and SysPharmPedia consortia, and others, (2021) ADRB2 haplotypes and asthma exacerbations in children and young adults: an individual participant data meta-analysis. Clinical and Experimental Allergy. ISSN 0954-7894

Karunaratne, D, Karunaratne, N, Wilmot, J, Vincent, T, Wright, J, Mahmood, N, Tang, A, Sam, A H, Reed, M and Howlett, D (2021) An online teaching resource to support UK medical student education during the Covid-19 pandemic: a descriptive account. Advances in Medical Education and Practice, 12. pp. 1317-1327. ISSN 1179-7258

Kennedy, Emma, Coulter, Eve Marie, Halliwell, Emma, Profitos-Peleja, Nuria, Walsby, Elisabeth, Clark, Barnaby, Phillips, Elizabeth H, Burley, Thomas A, Mitchell, Simon, Devereux, Stephen, Jones, Christopher Iain, Johnston, Rosalynd, Chevassut, Timothy J, Pepper, Chris, Pepper, Andrea G S and others, (2021) TLR9 expression in Chronic Lymphocytic Leukemia identifies a pro-migratory subpopulation and novel therapeutic target. Blood. pp. 1-32. ISSN 0006-4971

Kirkham, Frances, Pera, Alejandra, Simanek, Amanda M, Bano, Aalia, Morrow, George, Reus, Bernhard, Caserta, Stefano, Smith, Helen E, Davies, Kevin A, Rajkumar, Chakravarthi and Kern, Florian (2021) Cytomegalovirus infection is associated with an increase in aortic stiffness in older men which may be mediated in part by CD4 memory T-cells. Theranostics. ISSN 1838-7640

L

Latif, Anne-Louise, Newcombe, Ashley, Li, Sha, Gilroy, Kathryn, Robertson, Neil A, Lei, Xue, Stewart, Helen J S, Cole, John, Terradas, Maria Terradas, Rishi, Loveena, McGarry, Lynn, McKeeve, Claire, Reid, Claire, Clark, William, Chevassut, Timothy J T and others, (2021) BRD4-mediated repression of p53 is a target for combination therapy in AML. Nature Communications, 12 (1). a241 1-16. ISSN 2041-1723

Loyal, Lucie, Braun, Julian, Henze, Larissa, Kruse, Beate, Dingeldey, Manuela, Reimer, Ulf, Kern, Florian, Schwarz, Tatjana, Arndt, Lil Meyer, Thiel, Andreas and Thiel, Claudia Giesecke (2021) Cross-reactive CD4+T cells enhance SARS-CoV-2 immune responses upon infection and vaccination. 6th European Congress of Immunology, Virtual Conference, 1-4 September 2021. Published in: European Journal of Immunology. 51 (S1) 140-140. Wiley ISSN 0014-2980

Loyal, Lucie, Braun, Julian, Henze, Larissa, Kruse, Beate, Dingeldey, Manuela, Reimert, Ulf, Kern, Florian, Schwarz, Tatjana, Mangold, Maike, Unger, Clara, Dörfler, Friederike, Kadler, Shirin, Rosowski, Jennifer, Gürcan, Kübrah, Uyar-Aydin, Zehra and others, (2021) Cross-reactive CD4+ T cells enhance SARS-CoV-2 immune responses upon infection and vaccination. Science. pp. 1-18. ISSN 1095-9203

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Macken, Lucia, Palaniyappan, Naaventhan, Verma, Sumita and Aithal, Guruprasad (2021) Large volume paracentesis: to do or where to do? Gut, 70. pp. 2401-2402. ISSN 0017-5749

Magny, Emile G, Platero, Ana Isabel, Bishop, Sarah A, Pueyo, Jose I, Aguilar-Hidalgo, Daniel and Couso, Juan Pablo (2021) Pegasus, a small extracellular peptide enhancing the short-range diffusion of Wingless. Nature Communications, 12. a5660 1-11. ISSN 2041-1723

Maroteau, Cyrielle, Espuela-Ortiz, Antonio, Herrera-Luis, Esther, Srinivasan, Sundararajan, Carr, Fiona, Tavendale, Roger, Wilson, Karen, Hernandez-Pacheco, Natalia, Chalmers, James D, Turner, Steve, Mukhopadhyay, Somnath, Maitland-van der Zee, Anke-Hilse, Burchard, Esteban G, Pino-Yanes, Maria, Young, Simon, Lassi, Glenda, Platt, Adam and Palmer, Colin N A (2021) LTA4H rs2660845 association with montelukast response in early and late-onset asthma. PLoS One, 16 (9). a0257396 1-17. ISSN 1932-6203

Martin, Charlene, Shrestha, Anne, Morgan, Jenna, Bradburn, Michael, Herbert, Esther, Burton, Maria, Todd, Annaliza, Walters, Stephen, Ward, Sue, Holmes, Geoffrey, Reed, Malcolm, Collins, Karen, Robinson, ThompsonG, Ring, Alistair, Cheung, Kwok-Leung and others, (2021) Treatment choices for older women with primary operable breast cancer and cognitive impairment: results from a prospective, multicentre cohort study. Journal of Geriatric Oncology, 12 (5). pp. 705-713. ISSN 1879-4068

Masoli, Jane A H, Kirkham, Frances A and Rajkumar, Chakravarthi (2021) Atrial fibrillation and oral anticoagulation in older adults: an update. Age and Ageing, 50 (3). pp. 687-689. ISSN 0002-0729

Masoli, Jane A H, Sheppard, James P and Rajkumar, Chakravarthi (2021) Hypertension management in older patients-Are the guideline blood pressure targets appropriate? Age and Ageing. pp. 1-3. ISSN 0002-0729

Mattace-Raso, Francesco and Rajkumar, Chakravarthi (2021) Medicine is a science of uncertainty and an art of probability. Blood pressure management in older people. Age and Ageing, 50 (1). pp. 59-61. ISSN 0002-0729

Mercer, Judith S, Erickson-Owens, Debra A and Rabe, Heike (2021) Placental transfusion: may the “force” be with the baby. Journal of Perinatology, 41 (6). pp. 1495-1504. ISSN 0743-8346

Mitchell, Simon (2021) What will B will B: identifying molecular determinants of diverse B-cell fate decisions through systems biology. Frontiers in Cell and Developmental Biology, 8. a616592 1-8. ISSN 2296-634X

Morgan, J L, Shrestha, A, Reed, M W R, Herbert, E, Bradburn, M, Walters, S J, Martin, C, Collins, K, Ward, S, Holmes, G, Burton, M, Lifford, K, Edwards, A, Ring, A, Wright, Juliet and others, (2021) Bridging the age gap in breast cancer: impact of omission of breast cancer surgery in older women with oestrogen receptor-positive early breast cancer on quality-of-life outcomes. British Journal of Surgery, 108 (3). pp. 315-325. ISSN 0007-1323

Munro, Alasdair P S, Janani, Leila, Cornelius, Victoria, Aley, Parvinder K, Babbage, Gavin, Baxter, David, Bula, Marcin, Cathie, Katrina, Chatterjee, Krishna, Dodd, Kate, Enever, Yvanne, Gokani, Karishma, Goodman, Anna L, Green, Christopher A, Llewelyn, Martin J and others, (2021) Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial. The Lancet, 398 (10318). pp. 2258-2276. ISSN 0140-6736

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Pashler, Amy L, Towler, Benjamin P, Jones, Christopher I, Haime, Hope J, Burgess, Tom and Newbury, Sarah F (2021) Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identify disease-relevant transcripts containing G-rich motifs. RNA, 27 (10). pp. 1265-1280. ISSN 1355-8382

Patterson, Karen C, Rosenbach, Misha, Bravo, Paco E and Dubroff, Jacob G (2021) Stable extent of recurrently active cardiac and cutaneous sarcoidosis. Frontiers in Medicine, 8. p. 729229. ISSN 2296-858X

Pazan, Farhad, Petrovic, Mirko, Cherubini, Antonio, Onder, Graziano, Cruz-Jentoft, Alfonso J, Denkinger, Michael, van der Cammen, Tischa J M, Stevenson, Jennifer M, Ibrahim, Kinda, Rajkumar, Chakravarthi, Bakken, Marit Stordal, Baeyens, Jean-Pierre, Crome, Peter, Frühwald, Thomas, Gallaghar, Paul and others, (2021) Correction to: Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials. European Journal of Clinical Pharmacology, 77. pp. 1593-1594. ISSN 0031-6970

Pazan, Farhad, Petrovic, Mirko, Cherubini, Antonio, Onder, Graziano, Cruz-Jentoft, Alfonso J, Denkinger, Michael, van der Cammen, Tischa J M, Stevenson, Jennifer M, Ibrahim, Kinda, Rajkumar, Chakravarthi, Bakken, Marit Stordal, Baeyens, Jean-Pierre, Crome, Peter, Frühwald, Thomas, Gallaghar, Paul and others, (2021) Current evidence on the impact of medication optimization or pharmacological interventions on frailty or aspects of frailty: a systematic review of randomized controlled trials. European Journal of Clinical Pharmacology, 77. pp. 1-12. ISSN 0031-6970

Pellicer, Adelina, Fernández, Ramón, Jullien, Vincent, Gleeson, Clare, Bravo, María Carmen, Ortego, Paloma López, Sánchez, Laura, Ybarra, Marta, Rojas-Anaya, Héctor, Cabañas, Fernando, Koch, Armin, Smith, Andrea, Rabe, Heike, Neocirculation Consortium, and others, (2021) Pharmacokinetic study (phase I−II) of a new dobutamine formulation in preterm infants immediately after birth. Pediatric Research, 89. pp. 981-986. ISSN 0031-3998

Perry, Mark, Kemmis Betty, Sophia, Downes, Nicole, Andrews, Neil, MacKenzie, Simon, Guideline Committee, and Rajkumar, Chakravarthi (2021) Atrial fibrillation: diagnosis and management—summary of NICE guidance. BMJ, 373. n1150 1-6. ISSN 1759-2151

Phillips, Rupert, Wood, Henry, Weaving, Gary and Chevassut, Timothy (2021) Changes in full blood count parameters with age and sex: results of a survey of 900,000 patient samples from primary care. British Journal of Haematology, 192 (4). e102-e105. ISSN 0007-1048

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Rabe, Heike, Bhatt-Mehta, Varsha, Bremner, Stephen A, Ahluwalia, Aisling, Mcfarlane, Renske, Baygani, Simin, Batton, Beau, Klein, Agnes, Ergenekon, Ebru, Pesco Koplowitz, Luana, Dempsey, Eugene, Apele-Freimane, Dina, Iwami, Hiroko, Dionne, Janis M and International Neonatal Consortium, (2021) Antenatal and perinatal factors influencing neonatal blood pressure: a systematic review. Journal of Perinatology. pp. 1-13. ISSN 0743-8346

Rajkumar, Chakravarthi (2021) Correction to: Toward a geriatric approach to patients with advanced age and cardiovascular diseases: position statement of the EuGMS Special Interest Group on Cardiovascular Medicine. Eur Geriatr Med, 12. p. 429. ISSN 1878-7649

Ravandi, Farhad, Roboz, Gail J, Wei, Andrew H, Döhner, Hartmut, Pocock, Christopher, Selleslag, Dominik, Montesinos, Pau, Sayar, Hamid, Musso, Maurizio, Figuera-Alvarez, Angela, Safah, Hana, Tse, William, Sohn, Sang Kyun, Hiwase, Devendra, Chevassut, Timothy, Pierdomenico, Francesca, La Torre, Ignazia, Skikne, Barry, Bailey, Rochelle, Zhong, Jianhua, Beach, C L and Dombret, Herve (2021) Management of adverse events in patients with acute myeloid leukemia in remission receiving oral azacitidine: experience from the phase 3 randomized QUAZAR AML-001 trial. Journal of Hematology and Oncology, 14 (1). a133 1-14. ISSN 1756-8722

Reus, Bernhard, Caserta, Stefano, Larsen, Martin, Morrow, George, Bano, Aalia, Hallensleben, Michael, Rajkumar, Chakravarthi, Pera, Alejandra and Kern, Florian (2021) In-depth profiling of T-cell responsiveness to commonly recognized CMV antigens in older people reveals important sex differences. Frontiers in Immunology, 12. a707830 1-21. ISSN 1664-3224

Reynolds, Peter, Bustani, Porus, Darby, Colm, Fernandez Alvarez, Jose Ramon, Fox, Grenville, Jones, Steve, Robertson, Sara Jane, Vasu, Vimal and Roehr, Charles Christoph (2021) Less-invasive surfactant administration for neonatal respiratory distress syndrome: a consensus guideline. Neonatology, 118 (5). pp. 586-592. ISSN 1661-7800

Ring, Alistair, Battisti, Nicolò Matteo Luca, Reed, Malcolm W R, Herbert, Esther, Morgan, Jenna L, Bradburn, Michael, Walters, Stephen J, Collins, Karen A, Ward, Sue E, Holmes, Geoffrey R, Burton, Maria, Lifford, Kate, Wright, Juliet, Harder, Helena, Simcock, Richard, Age Gap TMG, and others, (2021) Bridging the age gap: observational cohort study of effects of chemotherapy and trastuzumab on recurrence, survival and quality of life in older women with early breast cancer. British Journal of Cancer, 125. pp. 209-219. ISSN 0007-0920

Rizan, Chantelle and Bhutta, Mahmood F (2021) Strategy for net-zero carbon surgery. British Journal of Surgery, 108 (7). pp. 737-739. ISSN 0007-1323

Rizan, Chantelle, Bhutta, Mahmood F, Reed, Malcom and Lillywhite, Rob (2021) The carbon footprint of waste streams in a UK hospital. Journal of Cleaner Production, 286. a125446. ISSN 0959-6526

Rizan, Chantelle, Reed, Malcolm and Bhutta, Mahmood F (2021) Environmental impact of personal protective equipment distributed for use by health and social care services in England in the first six months of the COVID-19 pandemic. Journal of the Royal Society of Medicine, 114 (5). pp. 250-263. ISSN 0141-0768

Robinson, Alyss V, Weaving, Gary, Philips, Barbara J, Eziefula, Alice C, Shipman, Kate E and Chevassut, Timothy (2021) Real-world experience of SARS-CoV-2 antibody assays in UK healthcare workers. Clinical Medicine. pp. 1-6. ISSN 1470-2118

Ruffles, Thomas, Jones, Christina J, Palmer, Colin, Turner, Steve, Grigg, Jonathan, Tavendale, Roger, Hogarth, Fiona, Rauchhaus, Petra, Pilvinyte, Kristina, Hannah, Romanie, Smith, Helen, Littleford, Roberta, Lipworth, Brian and Mukhopadhyay, Somnath (2021) Asthma prescribing according to Arg16Gly beta-2 genotype: a randomised trial in adolescents. European Respiratory Journal. ISSN 0903-1936

Ruffles, Tom, Lipworth, Brian and Mukhopadhyay, Somnath (2021) Considerations of a real life pragmatic clinical trial in adolescent asthma. European Respiratory Journal, 58. a2100461. ISSN 0903-1936

Ruffles, Tom J C, Goyal, Vikas, Marchant, Julie M, Masters, Brent, Yerkovich, Stephanie, Buntain, Helen, Cook, Anne, Schultz, Andre, Upham, John W, Champion, Anita, Versteegh, Lesley and Chang, Anne B (2021) Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. The Lancet Respiratory Medicine. ISSN 2213-2600

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Saad, Ramy, Tsoi, Kevin, Onac, Ioana Anamaria, Davies, Kevin A, Hajela, Vijay Kumar and Tacu, Cristina (2021) Streptococcus-associated vasculitis: a role for antibiotic therapy? ID Cases, 24. a01071 1-5. ISSN 2214-2509

Sadler, Jonathan, Wright, Juliet, Vincent, Timothy, Kurka, Thomas and Howlett, David (2021) What is the impact of Apps in medical education? A study of CAPSULE, a case-based learning App. BMJ Simulation & Technology Enhanced Learning, 7 (5). pp. 293-296. ISSN 2056-6697

Sam, A H, Reid, M D, Thakerar, V, Gurnell, M, Westacott, R, Yeates, P, Reed, M W R and Brown, C A (2021) The influence of candidates’ physical attributes on assessors’ ratings in clinical practice. Medical Teacher, 43 (5). pp. 554-559. ISSN 0142-159X

Samarasinghe, Ranmal A, Miranda, Osvaldo A, Buth, Jessie E, Mitchell, Simon, Ferando, Isabella, Watanabe, Momoko, Allison, Thomas F, Kurdian, Arinnae, Fotion, Namie N, Gandal, Michael J, Golshani, Peyman, Plath, Kathrin, Lowry, William E, Parent, Jack M, Mody, Istvan and Novitch, Bennett G (2021) Identification of neural oscillations and epileptiform changes in human brain organoids. Nature Neuroscience, 24. pp. 1488-1500. ISSN 1097-6256

Seidler, Anna Lene, Gyte, Gillian M L, Rabe, Heike, Díaz-Rossello, José L, Duley, Lelia, Aziz, Khalid, Costa-Nobre, Daniela Testoni, Davis, Peter G, Schmölzer, Georg M, Ovelman, Colleen, Askie, Lisa M and Soll, Roger (2021) Umbilical cord management for newborns < 34 weeks' gestation: a meta-analysis. Pediatrics, 147 (3). a20200576 1-20. ISSN 0031-4005

Shahvisi, Arianne (2021) Colonial monuments as slurring speech acts. Journal of Philosophy of Education. ISSN 0309-8249

Shahvisi, Arianne (2021) “FGM” vs. female “cosmetic” surgeries: why do they continue to be treated separately? International Journal of Impotence Research. pp. 1-5. ISSN 0955-9930

Shahvisi, Arianne (2021) Resisting wrongful explanations. Journal of Ethics and Social Philosophy, 19 (2). pp. 168-191. ISSN 1559-3061

Shao, Hao, Foley, David W, Huang, Shiliang, Abbas, Abdullahi Y, Lam, Frankie, Gershkovich, Pavel, Bradshaw, Tracey D, Pepper, Chris, Fischer, Peter M and Wang, Shudong (2021) Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents. European Journal of Medicinal Chemistry, 214. a13244 1-15. ISSN 0223-5234

Shears, Annalie, Fidler, Katy, Luck, Suzanne and Walter, Simone (2021) Routine vestibular function assessment in children with congenital CMV: are we ready? Hearing Journal, 74 (5). pp. 12-14. ISSN 0745-7472

Slob, Elise M A, Richards, Levi B, Vijverberg, Susanne J H, Longo, Cristina, Koppelman, Gerard H, Pijnenburg, Mariëlle W H, Bel, Elisabeth H D, Neerincx, Anne H, Luis, Esther Herrera, Perez‐Garcia, Javier, Chew, Fook Tim, Sio, Yang Yie, Andiappan, Anand K, Turner, Steve W, Mukhopadhyay, Somnath and others, (2021) Genome-wide association studies of exacerbations in children using long-acting beta2-agonists. Pediatric Allergy and Immunology. ISSN 0905-6157

Soares, Patricia, Fidler, Katy, Felton, Jessie, Jones, Christina J, Tavendale, Roger, Hövels, Anke, Bremner, Stephen, Palmer, Colin N A and Mukhopadhyay, Somnath (2021) An FCER2 polymorphism is associated with increased oral leukotriene receptor antagonists and allergic rhinitis prescribing. Clin Exp Allergy. pp. 1-4. ISSN 0954-7894

Sturrock, B R H, Chevassut, E I, Shahvisi, A and Chevassut, T J T (2021) Impact of affluence on the local spread of SARS-CoV2 during the first wave of the COVID-19 pandemic. Public Health in Practice, 2. a100141 1-3. ISSN 2666-5352

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Thieleman, Kara, Cacciatore, Joanne and Gorman, Richard (2021) “Perhaps something of beauty can grow:” experiences of care farming for grief. Death Studies. ISSN 0748-1187

Thwaites, Ryan S, Unterberger, Sarah, Chamberlain, Giselle, Gray, Henry, Jordan, Kelsey, Davies, Kevin A, Harrison, Neil A and Sacre, Sandra (2021) Expression of sterile-α and armadillo motif in rheumatoid arthritis monocytes correlates with TLR2 induced IL-1β and disease activity. Rheumatology. pp. 1-29. ISSN 1462-0324

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Unterberger, Sarah, Davies, Kevin A, Rambhatla, Srinivasa Bhargav and Sacre, Sandra (2021) Contribution of toll-like receptors and the NLRP3 inflammasome in rheumatoid arthritis pathophysiology. ImmunoTargets and Therapy, 10. pp. 285-298. ISSN 2253-1556

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Walker, Eleanor, Shaw, Sebastian C K, Reed, Malcolm and Anderson, John L (2021) The experiences of foundation doctors with dyspraxia: a phenomenological study. Advances in Health Sciences Education. ISSN 1382-4996

Weber, Thomas, Andrzej, Januszewicz, Rosei, Enrico Agabiti, Tsioufis, Konstantinos, Okorie, Michael, Stergiou, George S, Volpe, Massimo, Kreutz, Reinhold, Abraham, Gyorgy, Azizi, Michel, Barna, Istvan, Barroso, Weimar Kunz Sebba, Brguljan, Jana, Chapman, Neil, Rajkumar, Chakravarthi and others, (2021) The corona-virus disease 2019 pandemic compromised routine care for hypertension: a survey conducted among excellence centers of the European Society of Hypertension. Journal of Hypertension, 39 (1). pp. 190-195. ISSN 0263-6352

Wells, Geoffrey, Llewellyn, Carrie, Hiersche, Andreas, Minton, Ollie and Wright, Juliet (2021) Medical student anxiety in caring for dying patients and their family: a cross-sectional study. BMJ Supportive & Palliative Care. ISSN 2045-435X

West-Oram, Peter (2021) Solidarity is for other people: identifying derelictions of solidarity in responses to COVID-19. Journal of Medical Ethics, 47 (2). pp. 65-68. ISSN 0306-6800

West-Oram, Peter G N and Nunes, Jordanna A A (2021) Conscience absolutism via legislative amendment. Clinical Ethics. pp. 1-5. ISSN 1477-7509

Winter, Rebecca, Al-Jawad, Muna, Wright, Juliet, Shrewsbury, Duncan, Van Marwijk, Harm, Johnson, Helen and Levett, Tom (2021) What is meant by “frailty” in undergraduate medical education? A national survey of UK medical schools. European Geriatric Medicine, 12. pp. 355-362. ISSN 1878-7649

Wyld, Lynda, Reed, Malcolm W R, Morgan, Jenna, Collins, Karen, Ward, Sue, Holmes, Geoffrey R, Bradburn, Mike, Walters, Stephen, Burton, Maria, Herbert, Esther, Lifford, Kate, Edwards, Adrian, Ring, Alistair, Robinson, Thompson, Wright, Charlene and oithers, (2021) Bridging the age gap in breast cancer. Impacts of omission of breast cancer surgery in older women with oestrogen receptor positive early breast cancer. A risk stratified analysis of survival outcomes and quality of life. European Journal of Cancer, 142. pp. 48-62. ISSN 0959-8049