Items for Sussex Centre for Genome Damage and Stability in 2019

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Number of items: 32.

A

Addis, Owen (2019) Polo-like kinase 1 (PLK1) promotes centromere protection against a PICH/BLM-mediated deformation pathway. Doctoral thesis (PhD), University of Sussex.

Addis Jones, Owen, Tiwari, Ankana, Olukoga, Tomisin, Herbert, Alex and Chan, Kok-Lung (2019) PLK1 facilitates chromosome biorientation by suppressing centromere disintegration driven by BLM-mediated unwinding and spindle pulling. Nature Communications, 10 (1). pp. 1-17. ISSN 2041-1723

B

Bailey, Laura J, Bianchi, Julie and Doherty, Aidan J (2019) PrimPol is required for the maintenance of efficient nuclear and mitochondrial DNA replication in human cells. Nucleic Acids Research, 47 (8). pp. 4026-4038. ISSN 0305-1048

Baxter, Jonathan, Oliver, Antony W and Schalbetter, Stephanie A (2019) Are SMC complexes loop extruding factors? Linking theory with fact. BioEssays, 41 (1). 1800182 1-10. ISSN 1521-1878

Bigot, Nicolas, Day, Matthew, Baldock, Robbie A, Watts, Felicity Z, Oliver, Antony W and Pearl, Laurence H (2019) Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint. eLIfe. ISSN 2050-084X

Blanshard, Robert Christopher (2019) An investigation of genome stability in human female meiosis by genome-wide chromosome fingerprinting and copy number analysis. Doctoral thesis (PhD), University of Sussex.

Buist, David John (2019) Establishing a method to monitor replicative polymerase usage genome-wide in human cells. Doctoral thesis (PhD), University of Sussex.

C

Canela, Andres, Marman, Yaakov, Huang, Shar-yin N, Wutz, Gordana, Tang, Wen, Zagnol-iVieira, Guido, Callen, Elsa, Wong, Nancy, Day, Amanda, Peters, Jan-Michael, Pommier, Yves, Caldecott, Keith W and Nussenzweig, André (2019) Topoisomerase II-Induced chromosome breakage and translocation is determined by chromosome architecture and transcriptional activity. Molecular Cell. ISSN 1097-2765

Caser Tena, Teresa, Maerz, Lars, Szafranski, Karol, Groth, Marco, Blatte, Tamara, Donow, Cornelia, Matysik, Sabrina, Walther, Paul, Jeggo, Penelope A, Burkhalter, Martin and Philipp, Melanie (2019) Resting cells rely on the DNA helicase component MCM2 to build cilia. Nucleic Acids Research, 47 (1). pp. 134-151. ISSN 0305-1048

D

Deegan, Tom D, Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T P and Labib, Karim P M (2019) Pif1-Family helicases support fork convergence during DNA replication termination in eukaryotes. Molecular Cell, 74 (2). 231-244.e9. ISSN 1097-4164

E

Eckert, Aimee (2019) Validating Greatwall kinase as a potential target in cancer therapy. Doctoral thesis (PhD), University of Sussex.

F

Falquet, Benoît and Rass, Ulrich (2019) Structure-specific endonucleases and the resolution of chromosome underreplication. Genes, 10 (3). p. 232. ISSN 2073-4425

Fontana, Gabriele A, Hess, Daniel, Reinert, Julia K, Mattarocci, Stefano, Falquet, Benoît, Klein, Dominique, Shore, David, Thomä, Nicolas H and Rass, Ulrich (2019) Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane. Nature Communications, 10 (2535). pp. 1-14. ISSN 2041-1723

Fontana, Gabriele A and Rass, Ulrich (2019) Compartmentalized DNA repair: Rif1 S-acylation links DNA double-strand break repair to the nuclear membrane. Molecular & Cellular Oncology. ISSN 2372-3556

G

Goncalves, Maria B, Moehlin, Julien, Clarke, Earl, Grist, John, Hobbs, Carl, Carr, Antony M, Jack, Julian, Mendoza-Parra, Marco Antonio and Corcoran, Jonathan P T (2019) RARb agonist drug (C286) demonstrates efficacy in a pre-clinical neuropathic pain model restoring multiple pathways via DNA repair mechanisms. iScience, 20. pp. 554-566. ISSN 2589-0042

K

Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J, Stewart, Grant S, Wollnick, Bernd, Yigit, Gökhan and Caldecott, Keith W (2019) Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ. Neurology Genetics, 5 (2). pp. 1-7. ISSN 2376-7839

Karasozen, Yigit, Osbun, Joshua W, Parada, Carolina Angelica, Busald, Tina, Tatman, Philip, Gonzalez-Cuyar, Luis F, Hale, Christopher J, Alcantara, Diana, O'Driscoll, Mark, Dobyns, William B, Murray, Mitzi, Kim, Louis J, Byers, Peter, Dorschner, Michael O and Ferreira, Manuel (2019) Somatic PDGFRB activating variants in fusiform cerebral aneurysms. American Journal of Human Genetics, 104 (5). pp. 968-976. ISSN 1537-6605

Kozik, Zuzanna (2019) Investigation of DNA double-strand break-associated histone post-translational modifications using targeted mass spectrometry. Doctoral thesis (PhD), University of Sussex.

L

Leimbacher, Pia-Amata, Jones, Samuel E, Shorrocks, Ann-Marie K, de Marco Zompit, Mara, Day, Matthew, Blaauwendraad, Jordy, Bundschuh, Diana, Bonham, Sarah, Fischer, Roman, Fink, Daniel, Kessler, Benedikt M, Oliver, Antony W, Pearl, Laurence H, Blackford, Andrew N and Stucki, Manuel (2019) MDC1 interacts with TOPBP1 to maintain chromosomal stability during mitosis. Molecular Cell. ISSN 1097-2765

M

Maerz, Lars D, Casar Tena, Teresa, Gerhards, Julian, Donow, Cornelia, Jeggo, Penelope A and Philipp, Melanie (2019) Analysis of cilia dysfunction phenotypes in zebrafish embryos depleted of origin recognition complex factors. European Journal of Human Genetics, 27 (5). pp. 772-782. ISSN 1018-4813

Martinez-Macias, Maria Isabel, Moore, Duncan A Q, Green, Ryan L, Gomez-Herreros, Fernando, Naumann, Marcel, Hermann, Andreas, Van Damme, Philip, Hafezparast, Majid and Caldecott, Keith W (2019) FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I–induced DNA breakage and transcriptional stress. Life Science Alliance, 2 (2). e201800222 1-14. ISSN 2575-1077

Minchell, Nicola E (2019) DNA topological stress during DNA replication in Saccharomyces cerevisiae. Doctoral thesis (PhD), University of Sussex.

Muñoz-Hernández, Hugo, Pal, Mohinder, Rodríguez, Carlos F, Fernandez-Leiro, Rafael, Prodromou, Chrisostomos, Pearl, Laurence H and Llorca, Oscar (2019) Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Science Advances, 5 (5). eaaw1616 1-11. ISSN 2375-2548

P

Pai, Chen-Chen, Hsu, Kuo-Feng, Durley, Samuel C, Keszthelyi, Andrea, Kearsey, Stephen E, Rallis, Charalampos, Folkes, Lisa K, Deegan, Rachel, Wilkins, Sarah E, Pfister, Sophia X, De León, Nagore, Schofield, Christopher J, Bähler, Jürg, Carr, Antony and Humphrey, Timothy C (2019) An essential role for dNTP homeostasis following CDK-induced replication stress. Journal of Cell Science, 132 (6). jcs226969 1-16. ISSN 0021-9533

Polo, Luis M, Xu, Yingqi, Hornyak, Peter, Garces, Fernando, Zeng, Zhihong, Hailstone, Richard, Matthews, Steve J, Caldecott, Keith W, Oliver, Antony W and Pearl, Laurence H (2019) Efficient single-strand break repair requires binding to both poly(ADP-ribose) and DNA by the central BRCT domain of XRCC1. Cell Reports, 26 (3). 573-581.e5. ISSN 2211-1247

R

Rass, Ulrich (2019) Freedom of movement. Nature Chemical Biology, 15 (37). pp. 209-210. ISSN 1552-4450

Ren, Laifeng, Zeng, Ming, Tang, Zizhi, Li, Mingyuan, Wang, Ziaojun, Xu, Yang, Weng, Yuding, Wang, Xiaobo, Guo, Liandi, Zuo, Bing, Wang, Xin, Wang, Si, Lou, Jiangyan, Carr, Antony M, Jeggo, Penelope and others, (2019) The anti-resection activity of the X protein encoded by Hepatitis Virus B. Hepatology. ISSN 0270-9139

S

Shibata, Atsushi and Jeggo, Penny (2019) A historical reflection on our understanding of radiation-induced DNA double strand break repair in somatic mammalian cells; interfacing the past with the present. International Journal of Radiation Biology. ISSN 0955-3002

T

Tsuda, Masataka, Ogawa, Saki, Ooka, Masato, Kobayashi, Kaori, Hirota, Kouji, Wakasugi, Mitsuo, Matsunaga, Tsukasa, Sakuma, Tetsushi, Yamamoto, Takashi, Chikuma, Shunsuke, Sasanuma, Hiroyuki, Debatisse, Michelle, Doherty, Aidan J, Fuchs, Robert P and Takeda, Shunichi (2019) PDIP38/PolDIP2 controls the DNA damage tolerance pathways by increasing the relative usage of translesion DNA synthesis over template switching. PLoS ONE, 14 (3). e0213383 1-23. ISSN 1932-6203

V

Van Esch, Hilde, Colnaghi, Rita, Freson, Kathleen, Starokadomskyy, Petro, Zankl, Andreas, Backx, Liesbeth, Abramowicz, Iga, Outwin, Emily, Rohena, Luis, Faulkner, Claire, Leong, Gary M, Newbury-Ecob, Ruth A, Challis, Rachel C, Õunap, Katrin, Jaeken, Jacques, Seuntjens, Eve, Devriendt, Koen, Burstein, Ezra, Low, Karen J and O'Driscoll, Mark (2019) Defective DNA polymerase α-primase leads to X-linked intellectual disability associated with severe growth retardation, microcephaly, and hypogonadism. American Journal of Human Genetics, 104 (5). pp. 957-967. ISSN 1537-6605

X

xu, Wanping, Beebe, Kristin, Chavez, Juan D, Boysen, Marta, Lu, YinYing, Zuehlke, Abbey D, Keramisanou, Dimitra, Trepel, Jane B, Prodromou, Chrisostomos, Mayer, Matthias P, Bruce, James E, Gelis, Ioannis and Neckers, Len (2019) Hsp90 middle domain phosphorylation initiates a complex conformational program to recruit the ATPase-stimulating cochaperone Aha1. Nature Communications, 10. pp. 2574-2587. ISSN 2041-1723

Z

Zagnoli Vieira, Guido (2019) Investigating the effect of TDP2 absence in CRISPR/Cas9 knock-out or patient-derived cell lines. Doctoral thesis (PhD), University of Sussex.

This list was generated on Fri Dec 6 03:15:48 2019 GMT.