Items for Sussex Centre for Genome Damage and Stability in 2017

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Number of items: 40.

A

Abramowicz, Iga, Carpenter, Gillian, Alfieri, Mariaevelina, Colnaghi, Rita, Outwin, Emily, Parent, Philippe, Thauvin-Robinet, Christel, Iaconis, Daniela, Franco, Brunella and O'Driscoll, Mark (2017) Oral-Facial-Digital syndrome Type I cells exhibit impaired DNA repair; unanticipated consequences of defective OFD1 outside of the cilia network. Human Molecular Genetics, 26 (1). pp. 19-32. ISSN 0964-6906

Alcantara, Diana, Elmslie, Frances, Tetreault, Martine, Bareke, Eric, Hartley, Taila, Care4Rare Consortium, , Majewski, Jacek, Boycott, Kym, Innes, A Micheil, Dyment, David A and O'Driscoll, Mark (2017) SHORT syndrome due to a novel de novo mutation in PRKCE (Protein Kinase Cɛ) impairing TORC2-dependent AKT activation. Human Molecular Genetics, 26 (19). pp. 3713-3721. ISSN 1460-2083

Alcantara, Diana, Timms, Andrew E, Gripp, Karen, Baker, Laura, Park, Kaylee, Collins, Sarah, Cheng, Chi, Stewart, Fiona, Mehta, Sarju G, Saggar, Anand, Sztriha, László, Zombor, Melinda, Caluseriu, Oana, Mesterman, Ronit, Van Allen, Margot I, Jacquinet, Adeline, Ygberg, Sofia, Bernstein, Jonathan A, Wenger, Aaron M, Guturu, Harendra, Bejerano, Gill, Gomez-Ospina, Natalia, Lehman, Anna, Alfei, Enrico, Pantaleoni, Chiara, Conti, Valerio, Guerrini, Renzo, Moog, Ute, Graham Jr., John M, Hevner, Robert, Dobyns, William B, O'Driscoll, Mark and Mirzaa, Ghayda M (2017) Mutations of AKT3 are associated with a wide spectrum of developmental disorders including extreme megalencephaly. Brain, 140 (10). pp. 2610-2622. ISSN 0006-8950

Alt, Aaron, Dang, Hung Q, Wells, Owen S, Polo, Luis M, Smith, Matt A, McGregor, Grant A, Welte, Thomas, Lehmann, Alan R, Pearl, Laurence H, Murray, Johanne M and Oliver, Antony W (2017) Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nature Communications, 8. p. 14011. ISSN 2041-1723

B

Bailey, Laura and Doherty, Aidan (2017) Mitochondrial DNA replication: a PrimPol perspective. Biochemical Society Transactions, 45 (2). pp. 513-529. ISSN 0300-5127

Benstead-Hume, Graeme, Wooller, Sarah K and Pearl, Frances M G (2017) 'Big data' approaches for novel anti-cancer drug discovery. Expert opinion in drug discovery, 12 (6). pp. 599-609. ISSN 1746-045X

Bertoletti, Federica, Cea, Valentina, Liang, Chih-Chao, Lanati, Taiba, Maffia, Antonio, Avarello, Mario D M, Cipolla, Lina, Lehmann, Alan R, Cohn, Martin A and Sabbioneda, Simone (2017) Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle. Nucleic Acids Research, 45 (16). pp. 9441-9454. ISSN 1362-4962

Biehs, Ronja, Steinlage, Monika, Barton, Oliva, Juhász, Szilvia, Künzel, Julia, Spies, Julian, Shibata, Atsushi, Jeggo, Penny and Löbrich, Markus (2017) DNA double-strand break resection occurs during non-homologous end joining in G1 but is distinct from resection during homologous recombination. Molecular Cell, 65 (4). pp. 671-684. ISSN 1097-2765

Breslin, Claire, Mani, Rajam S, Fanta, Mesfin, Hoch, Nicolas, Weinfield, Michael and Caldecott, Keith W (2017) The RIR motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair. Journal of Biological Chemistry, 292. pp. 16024-16031. ISSN 1083-351X

C

Castañeda-García, A, Prieto, A I, Rodríguez-Beltrán, J, Alonso, N, Cantillon, D, Costas, C, Pérez-Lago, L, Zegeye, E D, Herranz, M, Plociński, P, Tonjum, T, García de Viedma, D, Paget, M, Waddell, S J, Rojas, A M, Doherty, A J and Blázquez, J (2017) A non-canonical mismatch repair pathway in prokaryotes. Nature Communications, 8. a14246. ISSN 2041-1723

D

Daigaku, Yasukazu, Etheridge, Thomas J, Nakazawa, Yuka, Nakayama, Mayumi, Watson, Adam T, Miyabe, Izumi, Ogi, Tomoo, Osborne, Mark A and Carr, Antony M (2017) PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast. PLoS Genetics, 13 (5). e1006789. ISSN 1553-7390

F

Falquet, Benoît and Rass, Ulrich (2017) A new role for Holliday junction resolvase Yen1 in processing DNA replication intermediates exposes Dna2 as an accessory replicative helicase. Microbial Cell, 4 (1). pp. 32-34. ISSN 2311-2638

Fleck, Oliver, Fahnøe, Ulrik, Vyff Løvschal, Katrine, Uwamahoro Gasasira, Marie-Fabrice, Marinova, Irina N, Kragelund, Birthe B, Carr, Antony M, Hartsuiker, Edgar, Holmberg, Christian and Nielsen, Olaf (2017) Deoxynucleoside salvage in fission yeast allows rescue of ribonucleotide reductase deficiency but not Spd1-Mediated inhibition of replication. Genes, 8 (5). a128. ISSN 2073-4425

G

Guilliam, Thomas A (2017) An investigation into the role, recruitment, and regulation of PrimPol in DNA replication restart. Doctoral thesis (PhD), University of Sussex.

Guilliam, Thomas A, Brissett, Nigel C, Ehlinger, Aaron, Keen, Benjamin A, Kolesar, Peter, Taylor, Elaine, Bailey, Laura J, Lindsay, Howard, Chazin, Walter J and Doherty, Aidan J (2017) Molecular basis for PrimPol recruitment to replication forks by RPA. Nature Communications, 8. a15222. ISSN 2041-1723

Gómez-Herreros, Fernando, Zagnoli-Vieira, Guido, Ntai, Ioanna, Martínez-Macías, María Isabel, Anderson, Rhona M, Herrero-Ruíz, Andrés and Caldecott, Keith (2017) TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription. Nature Communications, 8 (233). ISSN 2041-1723

H

Hall, Janet, Jeggo, Penny A, West, Catherine, Gomolka, Maria, Quintens, Roeal, Badie, Christophe, Laurent, Olivier, Aerts, An, Anastaov, Nataša, Azimzadehh, Omid and Others, (2017) Ionizing radiation biomarkers in epidemiological studies –An update. Mutation Research - Reviews, 771. pp. 59-84. ISSN 1383-5742

Hallett, Stephen T, Pastok, Martyna W, Morgan, R Marc L, Wittner, Anita, Blundell, Katie L I M, Felletar, Ildiko, Wedge, Stephen R, Prodromou, Chrisostomos, Noble, Martin E M, Pearl, Laurence H and Endicott, Jane A (2017) Differential regulation of G1 CDK complexes by the Hsp90-Cdc37 chaperone system. Cell Reports, 21 (5). pp. 1386-1398. ISSN 2211-1247

Hanzlikova, Hana, Gittens, William, Krejcikova, Katerina, Zeng, Zhihong and Caldecott, Keith W (2017) Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin. Nucleic Acids Research, 45 (5). pp. 2546-2557. ISSN 1362-4962

J

Jeggo, Penny and Barazzuol, Lara (2017) In vivo sensitivity of the embryonic and adult neural stem cell compartments to low-dose radiation. Journal of Radiation Research, 57 (S1). i2-i10. ISSN 0449-3060

Jeggo, Penny, Barazzuol, Lara and Ju, Limei (2017) A coordinated DNA damage response promotes adult quiescent neural stem cell activation. PLoS Biology, 15 (5). e2001264 1-25. ISSN 1544-9173

Jeggo, Penny and Löbrich, Markus (2017) A process of resection-dependent nonhomologous end joining involving the goddess Artemis. Trends in Biochemical Sciences, 42 (9). pp. 690-701. ISSN 0968-0004

Jeggo, Penny A, Downs, Jessica A and Gasser, Susan M (2017) Chromatin modifiers and remodellers in DNA repair and signalling. Philosophical Transactions B: Biological Sciences, 372 (1731). pp. 1-6. ISSN 0962–8436

Jeggo, Penny A and Löbrich, Markus (2017) [Editorial] DNA non-homologous end-joining enters the resection arena. Oncotarget, 8 (55). pp. 93317-93318. ISSN 1949-2553

L

Lehmann, Alan (2017) Xeroderma pigmentosum is a definite cause of Huntington's disease-like syndrome. Annals of Clinical and Translational Neurology, 5 (1). pp. 102-108. ISSN 2328-9503

Li, Zhaobo, Zhou, Lihong, Prodromou, Chrisostomos, Savic, Velibor and Pearl, Laurence H (2017) HECTD3 mediates an HSP90-dependent degradation pathway for protein kinase clients. Cell Reports, 19 (12). pp. 2515-2528. ISSN 2211-1247

M

Mattarocci, Stefano, Reinert, Julia K, Bunker, Richard D, Fontana, Gabriele A, Shi, Tianlai, Klein, Dominique, Cavadini, Simone, Faty, Mahamadou, Shyian, Maksym, Hafner, Lukas, Shore, David, Thomä, Nicolas H and Rass, Ulrich (2017) Rif1 maintains telomeres and mediates DNA repair by encasing DNA ends. Nature Structural and Molecular Biology, 24 (7). pp. 588-595. ISSN 1545-9985

McLean, Angela R, Adlen, Ella K, Cardis, Elisabeth, Elliot, Alex, Goodhead, Dudely T, Harms-Ringdahl, Mats, Hendry, Jolyon H, Hoskin, Peter, Jeggo, Penny A, Mackay, David J C, Muirhead, Colin R, Shepherd, John, Shore, Roy E, Thomas, Geraldine A, Wakeford, Richard and Godfray, H Charles J (2017) A restatement of the natural science evidence base concerning the health effects of low-level ionizing radiation. Proceedings of the Royal Society B, 284. pp. 1-7. ISSN 0080-464

Murray, Johanne (2017) Fission yeast strains with circular chromosomes require the 9-1-1 checkpoint complex for the viability in response to the anti-cancer drug 5-fluorodeoxyuridine. PLoS Medicine, 12 (11). e0187775 1-16. ISSN 1549-1277

O

O'Driscoll, Mark (2017) The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery. Journal of Pathology, 241 (2). pp. 192-207. ISSN 0022-3417

Ocasio, Tony, Sansook, Supojjanee, Jones, Alice Rhiannon, Roberts, Justin, Scott, Thomas, Tsoureas, Nikolaos, Coxhead, Peter, Guille, Matthew, Tizzard, Graham J, Coles, Simon J, Hochegger, Helfrid, Bradner, James E and Spencer, John (2017) Pojamide: An HDAC3-selective ferrocene analogue with remarkably enhanced redox-triggered ferrocenium activity in cells. Organometallics, 36 (17). pp. 3276-3283. ISSN 0276-7333

P

Pai, Chen-Chun, Kishkevich, Anastasiya, Deegan, Rachel S, Keszthelyi, Andrea, Folkes, Lisa, Kearsey, Stephen E, De León, Nagore, Soriano, Ignacio, de Bruin, Robertus Antonius Maria, Carr, Antony M and Humphrey, Timothy C (2017) Set2 methyltransferase facilitates DNA replication and promotes genotoxic stress responses through MBF-dependent transcription. Cell Reports, 20 (11). pp. 2693-2705. ISSN 2211-1247

Plocinski, Przemyslaw, Brissett, Nigel C, Bianchi, Julie, Brzostek, Anna, Korycka-Machała, Małgorzata, Dziembowski, Andrzej, Dziadek, Jaroslaw and Doherty, Aidan J (2017) DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria. Nature Communications, 1251 (2017). ISSN 2041-1723

R

Rivera-Calzada, Angel, Pal, Mohinder, Muñoz-Hernández, Hugo, Luque-Ortega, Juan R, Gil-Carton, David, Degliesposti, Gianluca, Skehel, J. Mark, Prodromou, Chrisostomos, Pearl, Laurence H and llorca, Oscar (2017) The structure of the R2TP complex defines a platform for recruiting diverse client proteins to the HSP90 molecular chaperone system. Structure, 25 (7). pp. 1145-1152. ISSN 0969-2126

S

Schalbettertter, S A, Goloborodko, A, Fudenberg, G, Belton, J M, Miles, C, Yu, M, Dekker, J, Mirny, L and Baxter, J (2017) SMC complexes differentially compact mitotic chromosomes according to genomic context. Nature Cell Biology, 19 (9). pp. 1071-1080. ISSN 1465-7392

V

Villahermosa, Desirée, Christensen, Olaf, Knapp, Karen and Fleck, Oliver (2017) Schizosaccharomyces pombe MutSα and MutLα maintain stability of tetra-nucleotide repeats and Msh3 of hepta-nucleotide repeats. G3, 7 (5). pp. 1463-1473. ISSN 2160-1836

Villahermosa, Desirée and Fleck, Oliver (2017) Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNALys UUU modifications. Scientific Reports, 7 (1). ISSN 2045-2322

Villahermosa, Desirée, Knapp, Karen and Fleck, Oliver (2017) A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents. Current Genetics, 63 (6). pp. 1081-1091. ISSN 0172-8083

W

Wooller, Sarah K, Benstead-Hume, Graeme, Chen, Xiangrong, Ali, Yusuf and Pearl, Frances MG (2017) Bioinformatics in translational drug discovery. Biosience Reports, 37 (4). pp. 1-13. ISSN 0144-8463

Z

Zeng, Zhihong, Rulten, Stuart L, Breslin, Claire, Zlatanou, Anastasia, Coulthard, Victoria and Caldecott, Keith (2017) Acylpeptide hydrolase is a component of the cellular response to DNA damage. DNA Repair, 58. pp. 52-61. ISSN 1568-7864

This list was generated on Tue Oct 15 20:53:42 2019 BST.