Items for Sussex Centre for Genome Damage and Stability in 2012

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Number of items: 37.

A

Alagoz, M, Gilbert, D C, El-Khamisy, S and Chalmers, A J (2012) DNA repair and resistance to topoisomerase I inhibitors: mechanisms, biomarkers and therapeutic targets. Current Medicinal Chemistry, 19 (23). pp. 3874-3885. ISSN 0929-8673

Ali, Ammar A E, Timinszky, Gyula, Arribas-Bosacoma, Raquel, Kozlowski, Marek, Hassa, Paul O, Hassler, Markus, Ladurner, Andreas G, Pearl, Laurence H and Oliver, Antony W (2012) The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks. Nature Structural & Molecular Biology, 9 (7). pp. 685-692. ISSN 1545-9985

B

Bass, Kirstin L, Murray, Johanne M and O'Connell, Matthew J (2012) Brc1-dependent recovery from replication stress. Journal of Cell Science, 125 (11). pp. 2753-2764. ISSN 0021-9533

Baxter, Jon (2012) A model for chromosome condensation based on the interplay between condensin and topoisomerase II. Trends in Genetics, 28 (3). pp. 110-117. ISSN 0168-9525

Brownlee, Peter M, Chambers, Anna L, Oliver, Antony W and Downs, Jessica A (2012) Cancer and the bromodomains of BAF180. Biochemical Society Transactions, 40 (2). pp. 364-369. ISSN 0300-5127

Busygina, Valeria, Saro, Dorina, Williams, Gareth, Leung, Wing-Kit, Say, Amanda F, Sehorn, Michael G, Sung, Patrick and Tsubouchi, Hideo (2012) Novel attributes of Hed1 affect dynamics and activity of the Rad51 presynaptic filament during meiotic recombination. Journal of Biological Chemistry, 287 (2). pp. 1566-1575. ISSN 0021-9258

C

Campillo-Funollet, E, Grün, G and Klingbeil, F (2012) On modeling and simulation of electrokinetic phenomena in two-phase flow with general mass densities. SIAM Journal on Applied Mathematics, 72 (6). pp. 1899-1925. ISSN 0036-1399

Chambers, A L, Brownlee, P M, Durley, S C, Beacham, T, Kent, N A and Downs, J A (2012) The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses. PLoS ONE, 7 (2). e32016. ISSN 1932-6203

Chambers, Anna L and Downs, Jessica A (2012) The RSC and INO80 chromatin-remodeling complexes in DNA double-strand break repair. Progress in molecular biology and translational science, 110. pp. 229-261. ISSN 1878-0814

Chambers, Anna L, Ormerod, Georgina, Durley, Samual C, Sing, Tina L, Brown, Grant W, Kent, Nicholas A and Downs, Jessica A (2012) The INO80 chromatin remodeling complex prevents polyploidy and maintains normal chromatin structure at centromeres. Genes & Development, 26 (23). pp. 2590-2603. ISSN 0890-9369

D

Durand-Dubief, Mickaël, Will, William Ryan, Petrini, Edoardo, Theodorou, Delphine, Harris, Rachael R., Crawford, Margaret R., Paszkiewicz, Konrad, Krueger, Felix, Correra, Rosa Maria, Vetter, Anna T., Miller, J. Ross, Kent, Nicholas A. and Varga-Weisz, Patrick (2012) SWI/SNF-like chromatin remodeling factor Fun30 supports point centromere function in S. cerevisiae. PLoS Genetics, 8 (9). e1002974. ISSN 1553-7390

F

Farmer, Sarah, Hong, Eun-Jin, Leung, Wing-Kit, Argunhan, Bilge, Terentyev, Yaroslav, Humphryes, Neil, Toyoizumi, Hiroshi and Tsubouchi, Hideo (2012) Budding yeast Pch2, a widely conserved meiotic protein, is involved in the initiation of meiotic recombination. PLoS ONE, 7 (6). e39724. ISSN 1932-6203

Fitzgerald, Brendan, O'Driscoll, Mark, Chong, Karen, Keating, Sarah and Shannon, Patrick (2012) Neuropathology of fetal stage Seckel syndrome: A case report providing a morphological correlate for the emerging molecular mechanisms. Brain and Development, 34 (3). pp. 238-243. ISSN 0387-7604

H

Hu, Jiazhi, Sun, Lei, Shen, Fenfen, Chen, Yufei, Hua, Yu, Liu, Yang, Zhang, Mian, Hu, Yiren, Wang, Qingsong, Xu, Wei, Sun, Fei, Ji, Jianguo, Murray, Johanne M, Carr, Antony M and Kong, Daochun (2012) The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing. Cell, 149 (6). pp. 1221-1232. ISSN 1097-4172

Hudson, Jessica J R, Chiang, Shih-Chieh, Wells, Owen S, Rookyard, Chris and El-Khamisy, Sherif F (2012) SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair. SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair., 3. p. 733. ISSN 2041-1723

K

Kerzendorfer, Claudia, Hannes, Femke, Colnaghi, Rita, Abramowicz, Iga, Carpenter, Gillian, Vermeesch, Joris Robert and O'Driscoll, Mark (2012) Characterizing the functional consequences of haploinsufficiency of NELF-A (WHSC2) and SLBP identifies novel cellular phenotypes in Wolf-Hirschhorn syndrome. Human Molecular Genetics, 21 (10). pp. 2181-2193. ISSN 0964-6906

L

Lando, David, Endesfelder, Ulrike, Berger, Harald, Subramanian, Lakxmi, Dunne, Paul D, McColl, James, Klenerman, David, Carr, Antony M, Sauer, Markus, Allshire, Robin C, Heilemann, Mike and Laue, Ernest D (2012) Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast. Open Biology, 2 (7). p. 120078. ISSN 2046-2441

Lehmann, Alan R (2012) DNA repair, DNA replication and human disorders: A personal journey. DNA Repair, 11 (4). pp. 328-334. ISSN 1568-7864

Lin, Su-Jiun, Wardlaw, Christopher Paul, Morishita, Takashi, Miyabe, Izumi, Chahwan, Charly, Caspari, Thomas, Schmidt, Ulrike, Carr, Antony and Garcia, Valerie (2012) The Rad4TopBP1 ATR-Activation domain functions in G1/S phase in a chromatin-dependent manner. PLoS Genetics, 8 (6). ISSN 1553-7390

M

Meier, Christoph, Brookings, Daniel C, Ceska, Thomas A, Doyle, Carl, Gong, Haiping, McMillan, David, Saville, Giles P, Mushtaq, Adeel, Knight, David, Reich, Stefanie, Pearl, Laurence H, Powell, Keith A, Savva, Renos and Allen, Rodger A (2012) Engineering human MEK-1 for structural studies: A case study of combinatorial domain hunting. Journal of Structural Biology, 177 (2). pp. 329-334. ISSN 1095-8657

Murray, Johanne M, Stiff, Tom and Jeggo, Penny A (2012) DNA double-strand break repair within heterochromatic regions. Biochemical Society Transactions, 40 (1). pp. 173-178. ISSN 0300-5127

N

Nakazawa, Yuka, Sasaki, Kensaku, Mitsutake, Norisato, Matsuse, Michiko, Shimada, Mayuko, Nardo, Tiziana, Takahashi, Yoshito, Ohyama, Kaname Ohyama, Ito, Kosei, Mishima, Hiroyuki, Nomura, Masayo, Kinoshita, Akira, Ono, Shinji, Takenaka, Katsuya, Masuyama, Ritsuko, Kudo, Takashi, Slor, Hanoch, Utani, Atsushi, Tateishi, Satoshi, Yamashita, Shunichi, Stefanini, Miria, Lehmann, Alan R, Yoshiura, Koh-ichiro and Ogi, Tomoo (2012) Mutations in UVSSA cause UV-sensitive syndrome and impair RNA polymerase IIo processing in transcription-coupled nucleotide-excision repair. Nature Genetics, 44 (5). pp. 586-592. ISSN 1061-4036

Niimi, Atsuko, Chambers, Anna L, Downs, Jessica A and Lehmann, Alan R (2012) A role for chromatin remodellers in replication of damaged DNA. Nucleic Acids Research, 40 (15). pp. 7393-7403. ISSN 0305-1048

O

O'Driscoll, Mark (2012) Diseases associated with defective responses to DNA damage. Cold Spring Harbor Perspectives in Biology, 4 (12). :a012773. ISSN 1943-0264

Ogi, Tomoo, Walker, Sarah, Stiff, Tom, Hobson, Emma, Limsirichaikul, Siripan, Carpenter, Gillian, Prescott, Katrina, Suri, Mohnish, Byrd, Philip J, Matsuse, Michiko, Mitsutake, Norisato, Nakazawa, Yuka, Vasudevan, Pradeep, Barrow, Margaret, Stewart, Grant S, Taylor, A Malcolm R, O'Driscoll, Mark and Jeggo, Penny A (2012) Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome. PLoS Genetics, 8 (11). e1002945. ISSN 1553-7390

P

Pernot, Eileen, Hall, Janet, Baatout, Sarah, Benotmane, Mohammed Abderrafi, Blanchardon, Eric, Bouffler, Simon, El Saghire, Houssein, Gomolka, Maria, Guertler, Anne, Harms-Ringdahl, Mats, Jeggo, Penny and et al, (2012) Ionizing radiation biomarkers for potential use in epidemiological studies. Mutation Research - Reviews, 751 (2). pp. 258-286. ISSN 1383-5742

Prodromou, Chrisostomos (2012) The 'active life' of Hsp90 complexes. BBA - Molecular Cell Research, 1823 (3). pp. 614-623. ISSN 0006-3002

R

Reynolds, John J, Walker, Alexandra K, Gilmore, Edward C, Walsh, Christopher A and Caldecott, Keith W (2012) Impact of PNKP mutations associated with microcephaly, seizures and developmental delay on enzyme activity and DNA strand break repair. Nucleic Acids Research, 40 (14). pp. 6608-6619. ISSN 1362-4962

Rivière, Jean-Baptiste, Mirzaa, Ghayda M, O'Roak, Brian J, Beddaoui, Margaret, Alcantara, Diana, Conway, Robert L, St-Onge, Judith, Schwartzentruber, Jeremy A, Gripp, Karen W, Nikkel, Sarah M, Worthylake, Thea, Sullivan, Christopher T, Ward, Thomas R, Butler, Hailly E, Kramer, Nancy A, Albrecht, Beate, Armour, Christine M, Armstrong, Linlea, Caluseriu, Oana, Cytrynbaum, Cheryl, Drolet, Beth A, Innes, A Micheil, Lauzon, Julie L, Lin, Angela E, Mancini, Grazia M S, Meschino, Wendy S, Reggin, James D, Saggar, Anand K, Lerman-Sagie, Tally, Uyanik, Gökhan, Weksberg, Rosanna, Zirn, Birgit, Beaulieu, Chandree L, (FORGE):, Finding of Rare Disease Genes Canada Consortium, Majewski, Jacek, Bulman, Dennis E, O'Driscoll, Mark, Shendure, Jay, Graham Jr, John M, Boycott, Kym M and Dobyns, William B (2012) De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes. Nature Genetics, 44 (8). pp. 934-940. ISSN 1546-1718

S

Sale, Julian E, Lehmann, Alan R and Woodgate, Roger (2012) Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nature Reviews Molecular Cell Biology, 13. pp. 141-152. ISSN 1471-0072

Sharp, Swee Y, Roe, S Mark, Kazlauskas, Egidijus, Čikotienė, Inga, Workman, Paul, Matulis, Daumantas and Prodromou, Chrisostomos (2012) Co-crystalization and in vitro biological characterization of 5-Aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors. PLoS Genetics, 7(9) (e44642). ISSN 1553-7390

T

Tanaka, Akio, Weinel, Sarah, Nagy, Nikoletta, O'Driscoll, Mark, Lai-Cheong, Joey E, Kulp-Shorten, Carol L, Knable, Alfred, Carpenter, Gillian, Fisher, Sheila A, Hiragun, Makiko, Yanase, Yuhki, Hide, Michihiro, Callen, Jeffrey and McGrath, John A (2012) Germline Mutation in ATR in Autosomal- Dominant Oropharyngeal Cancer Syndrome. American Journal of Human Genetics, 90 (3). pp. 511-517. ISSN 0002-9297

Tang, Zhaohua, Luca, Maria, Taggart-Murphy, Laura, Portillo, Jessica, Chang, Cathey, Guven, Ayse, Lin, Ren-Jang, Murray, Johanne and Carr, Antony (2012) Interacting factors and cellular localization of SR protein-specific kinase Dsk1. Experimental Cell Research, 318 (16). pp. 2071-2084. ISSN 0014-4827

Toyoizumi, Hiroshi and Tsubouchi, Hideo (2012) Estimating the number of double-strand breaks formed during meiosis from partial observation. Journal of Computational Biology, 19 (12). pp. 1277-1283. ISSN 1066-5277

Tsutsumi, Shinji, Mollapour, Mehdi, Prodromou, Chrisostomos, Lee, Chung-Tien, Panaretou, Barry, Yoshida, Soichiro, Mayer, Matthias P and Neckers, Leonard M (2012) Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity. Proceedings of the National Academy of Sciences, 109 (8). pp. 2937-2942. ISSN 1091-6490

Z

Zeng, Z, Sharma, A, Ju, L, Murai, J, Umans, L, Vermeire, L, Pommier, Y, Takeda, S, Huylebroeck, D, Caldecott, K and El-Khamisy, S (2012) TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1. Nucleic Acids Research, 40 (17). pp. 8371-8380. ISSN 1362-4962

Zheng, Yupeng, Sweet, Steve M M, Popovic, Relja, Martinez-Garcia, Eva, Tipton, Jeremiah D, Thomas, Paul M, Licht, Jonathan D and Kelleher, Neil L (2012) Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3. Proceedings of the National Academy of Sciences of the United States of America (PNAS) ISSN 1091-6490, 109 (34). pp. 13549-13554. ISSN 1091-6490

This list was generated on Tue Oct 15 03:48:33 2019 BST.