Items for Sussex Centre for Genome Damage and Stability in 2011

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Number of items: 51.

A

Ali, MMU, Bagratuni, T, Davenport, EL, Nowak, PR, Silva-Santiestaban, MC, Hardcastle, A, McAndrews, C, Rowlands, MG, Morgan, GJ, Aherne, W, Collins, I, Davies, FE and Pearl, Laurence (2011) Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response. EMBO Journal, 30 (5). pp. 894-905. ISSN 0261-4189

Anderson, Victoria E, Walton, Michael I, Eve, Paul D, Boxall, Katherine J, Antoni, Laurent, Caldwell, John J, Aherne, Wynne, Pearl, Laurence H, Oliver, Antony W, Collins, Ian and Garrett, Michelle D (2011) CCT241533 Is a Potent and Selective Inhibitor of CHK2 that Potentiates the Cytotoxicity of PARP Inhibitors. Cancer Research, 71 (2). pp. 463-472. ISSN 0008-5472

B

Baxter, J and Aragón, L (2011) Physical Linkages between Sister Chromatids and Their Removal during Yeast Chromosome Segregation. Cold Spring Harbor Symposia on Quantitative Biology. ISSN 0091-7451

Baxter, J, Sen, N, López Martínez, V, Monturus De Carandini, M E, Schwartzman, J B, Diffley, J F X and Aragón, L (2011) Positive supercoiling of mitotic DNA drives decatenation by topoisomerase II in eukaryotes. Science, 331 (6022). pp. 1328-32. ISSN 0036-8075

Bicknell, Louise S, Walker, Sarah, Klingseisen, Anna, Stiff, Tom, Leitch, Andrea, Kerzendorfer, Claudia, Martin, Carol-Anne, Yeyati, Patricia, Al Sanna, Nouriya, Bober, Michael, Johnson, Diana, Wise, Carol, Jackson, Andrew P, O'Driscoll, Mark and Jeggo, Penny A (2011) Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome. Nature Genetics, 43 (4). pp. 350-355. ISSN 1061-4036

Boos, Dominik, Sanchez-Pulido, Luis, Rappas, Mathieu, Pearl, Laurence H, Oliver, Antony W, Ponting, Chris P and Diffley, John F X (2011) Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans. Current Biology, 21 (13). pp. 1152-1157. ISSN 0960-9822

Brissett, Nigel C, Martin, Maria J, Pitcher, Robert S, Bianchi, Julie, Juarez, Raquel, Green, Andrew J, Fox, Gavin C, Blanco, Luis and Doherty, Aidan J (2011) Structure of a preternary complex involving a prokaryotic NHEJ DNA polymerase. Molecular Cell, 41 (2). pp. 221-231. ISSN 1097-2765

C

Caldwell, John J, Welsh, Emma J, Matjissen, Cornelis, Anderson, Victoria E, Antoni, Laurent, Boxall, Kathy, Urban, Frederique, Hayes, Angela, Raynaud, Florence I, Rigoreau, Laurent J M, Raynham, Tony, Aherne, G Wynne, Pearl, Laurence H, Oliver, Antony W, Garrett, Michelle D and Collins, Ian (2011) Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2. Journal of Medicinal Chemistry, 54 (2). pp. 580-590. ISSN 0022-2623

Colnaghi, Rita, Carpenter, Gillian, Volker, Marcel and O'Driscoll, Mark (2011) The Consequences of structural genomic alterations in humans: Genomic Disorders, genomic instability and cancer. Seminars in Cell and Developmental Biology, 22 (8). pp. 875-885. ISSN 1084-9521

Colnaghi, Rita, Carpenter, Gillian, Volker, Marcel and O'Driscoll, Mark (2011) The consequences of structural genomic alterations in humans: Genomic Disorders, genomic instability and cancer. Seminars in Cell & Developmental Biology.

Colnaghi, Rita, Carpenter, Gillian, Volker, Marcel and O'Driscoll, Mark (2011) The consequences of structural genomic alterations in humans: genomic disorders, genomic instability & cancer. Seminars in Cell & Developmental Biology, 22 (8). pp. 875-885. ISSN 10849521

Cuomo, Maria Emanuela, Platt, Georgina M, Pearl, Laurence H and Mittnacht, Sibylle (2011) Cyclin-cyclin-dependent kinase regulatory response is linked to substrate recognition. Journal of Biological Chemistry, 286 (11). pp. 9713-9725. ISSN 0021-9258

D

Day, James E H, Sharp, Swee Y, Rowlands, Martin G, Aherne, Wynne, Hayes, Angela, Raynaud, Florence I, Lewis, William, Roe, S Mark, Prodromou, Chrisostomos, Pearl, Laurence H, Workman, Paul and Moody, Christopher J (2011) Targeting the Hsp90 Molecular Chaperone with Novel Macrolactams. Synthesis, Structural, Binding, and Cellular Studies. ACS Chemical Biology, 6 (12). pp. 1339-1347. ISSN 1554-8929

E

El-Khamisy, Sherif (2011) To live or to die: a matter of processing damaged DNA termini in neurons. EMBO Molecular Medicine, 3 (2). pp. 78-88. ISSN 17574676

F

Farmer, Sarah, Leung, Wing-Kit and Tsubouchi, Hideo (2011) Characterization of meiotic recombination initiation sites using pulsed-field gel electrophoresis. In: Tsubouchi, Hideo (ed.) DNA recombination: methods and protocols. Springer protocols, 745 . Humana Press, New York. ISBN 9781617791284

G

Garces, Fernando, Pearl, Laurence H and Oliver, Antony W (2011) The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase. Molecular Cell, 44 (3). 385 - 396. ISSN 1097-2765

Garcia, V, Phelps, S E, Gray, S and Neale, M J (2011) Bidirectional resection of DNA double-strand breaks by Mre11 and Exo1. Nature, 478 (7369). pp. 241-244. ISSN 0028-0836

Gatz, Susanne A, Ju, Limei, Gruber, Ralph, Hoffmann, Eva, Carr, Antony M, Wang, Zhao-Qi, Liu, Cong and Jeggo, Penny A (2011) Requirement for DNA Ligase IV during Embryonic Neuronal Development. Journal of Neuroscience, 31. pp. 10088-100100.

Goodarzi, Aaron A, Kurka, Thomas and Jeggo, Penelope A (2011) KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nature Structural and Molecular Biology, 18 (7). pp. 831-839. ISSN 1545-9993

Göhler, Thomas, Sabbioneda, Simone, Green, Catherine M and Lehmann, Alan R (2011) ATR-mediated phosphorylation of DNA polymerase η is needed for efficient recovery from UV damage. Journal of Cell Biology, 192 (2). pp. 219-227. ISSN 0021-9525

H

Harvard, Chansonette, Strong, Emma, Mercier, Eloi, Colnaghi, Rita, Alcantara, Diana, Chow, Eva, Martell, Sally, Tyson, Christine, Hrynchak, Monica, McGillivray, Barbara, Hamilton, Sara, Marles, Sandra, Mhanni, Aziz, Dawson, Angelika J, Pavlidis, Paul, Qiao, Ying, Holden, Jeanette J, Lewis, Suzanne M E, O'Driscoll, Mark and Rajcan-Separovic, Evica (2011) Understanding the impact of 1q21.1 Copy Number Variant. Orphanet Journal of Rare Diseases, 6 (1 (54)).

Havard, Chansonette, Strong, Emma, Mercier, Eloi, Colnaghi, Rita, Alcantara, Diana Rita Ralha, Chow, Eva, Martell, Sally, Tyson, Christine, Hrynchak, Monica, McGillivray, Barbara, Hamilton, Sara, Marles, Sandra, Mhanni, Aziz, Dawson, Angelika J, Pavlidis, Paul and Qiao, Ying (2011) Understanding the impact of 1q21.1 copy number variant. Orphanet Journal of Rare Diseases, 6 (54). pp. 1-12. ISSN 1750-1172

Hegarat, Nadia, Smith, Ewan, Nayak, Gowri, Takeda, Shunichi, Eyers, Patrick A and Hochegger, Helfrid (2011) Aurora A and Aurora B jointly coordinate chromosome segregation. Journal of Cell Biology, 195 (7). pp. 1103-1113. ISSN 0021-9525

Hoffmann, Eva (2011) Chromosome Recombination. Seminars in Cell and Developmental Biology, 22 (8). p. 865. ISSN 1084-9521

Huang-Doran, I, Bicknell, LS, Finucane, FM, Rocha, N, Porter, KM, Tung, YCL, Szekeres, F, Krook, A, Nolan, JJ, O'Driscoll, Mark, Bober, M, O'Rahilly, S, Jackson, AP and Semple, R.K (2011) Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes. Diabetes, 60 (3). pp. 925-935. ISSN 00121797

Hudson, Jessica J. R., Bednarova, Katerina, Kozakova, Lucie, Liao, Chunyan, Guerineau, Marc, Colnaghi, Rita, Vidot, Susanne, Marek, Jaromir, Bathula, Sreenivas R., Lehmann, Alan R. and Palecek, Jan (2011) Interactions between the Nse3 and Nse4 Components of the SMC5-6 Complex Identify Evolutionarily Conserved Interactions between MAGE and EID Families. PLoS ONE, 6 (2). pp. 1-14. ISSN 1932-6203

J

Jozwiakowski, Stanislaw and Connolly, BA (2011) A modified family-B archaeal DNA polymerase with reverse transcriptase activity. Chembiochem : a European journal of chemical biology, 12 (1). pp. 35-7. ISSN 14394227

K

Kerzendorfer, Claudia, Hart, Lesley, Colnaghi, Rita, Carpenter, Gillian, Alcantara, Diana, Outwin, Emily, Carr, Antony M and O'Driscoll, Mark (2011) CUL4B-deficiency in humans: Understanding the clinical consequences of impaired Cullin 4-RING E3 ubiquitin ligase function. Mechanisms of Ageing and Disease.

L

Lehmann, Alan R (2011) Ubiquitin-family modifications in the replication of DNA damage. FEBS Letters, 585 (18). pp. 2772-2779. ISSN 0014-5793

Lehmann, Alan R, McGibbon, David and Stefanini, Miria (2011) Xeroderma Pigmentosum. Orphanet Journal of Rare Diseases, 6. ISSN 1750-1172

Lehmann, Alan R. (2011) DNA polymerases and repair synthesis in NER in human cells. DNA Repair, 10 (7). pp. 730-733. ISSN 1568-7864

M

Maclagan, Kate, Tommasi, Rita, Laurine, Emmanuelle, Prodromou, Chrisostomos, Driscoll, Paul C, Pearl, Laurence H, Reich, Stefanie and Savva, Renos (2011) A combinatorial method to enable detailed investigation of protein–protein interactions. Future Medicinal Chemistry, 3 (3). pp. 271-282. ISSN 1756-8919

Martinez-Garcia, Eva, Popovic, Relja, Min, Dong-Joon, Sweet, Steve M M, Thomas, Paul M, Zamdborg, Leonid, Heffner, Aaron, Will, Christine, Lamy, Laurence, Staudt, Louis M, Levens, David L, Kelleher, Neil L and Licht, Jonathan D (2011) The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood, 117 (1). pp. 211-220. ISSN 0006-4971

Miyabe, Izumi, Kunkel, Thomas A and Carr, Antony M (2011) The major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conserved. PLoS Genetics, 7 (12). e1002407. ISSN 1553-7390

Mollapour, Mehdi, Tsutsumi, Shinji, Truman, Andrew W, Xu, Wanping, Vaughan, Cara K, Beebe, Kristin, Konstantinova, Anna, Vourganti, Srinivas, Panaretou, Barry, Piper, Peter W, Trepel, Jane B, Prodromou, Chrisostomos, Pearl, Laurence H and Neckers, Len (2011) Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Molecular Cell, 41 (6). pp. 672-681. ISSN 1097-2765

Morris, Edward P, Rivera-Calzada, Angel, da Fonseca, Paula C A, Llorca, Oscar, Pearl, Laurence H and Spagnolo, Laura (2011) Evidence for a remodelling of DNA-PK upon autophosphorylation from electron microscopy studies. Nucleic Acids Research, 39 (13). pp. 5757-5767. ISSN 1362-4962

O

Outwin, Emily, Carpenter, Gillian, Bi, Weimin, Withers, Marjorie A, Lupski, James R and O'Driscoll, Mark (2011) Increased RPA1 gene dosage affects genomic stability potentially contributing to 17p13.3 duplication syndrome. PLoS Genetics, 7 (8). e1002247. ISSN 1553-7390

P

Pan, J, Sasaki, M, Kniewel, R, Murakami, H, Blitzblau, H.G, Tischfield, S.E, Zhu, X, Neale, Matt, Jasin, M, Socci, N.D, Hochwagen, A and Keeney, S (2011) A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation. Cell, 114 (5). pp. 719-731. ISSN 00928674

R

Raffan, Eleanor, Hurst, Liam A, Al Turki, Saeed, Carpenter, Gillian, Scott, Carol, Daly, Allan, Coffey, Alison, Bhaskar, Sanjeev, Howard, Eleanor, Khan, Naz, Kingston, Helen, Palotie, Aarno, Savage, David B, O'Driscoll, Mark, Smith, Claire, O'Rahilly, Stephen, Barroso, Inês and Semple, Robert K (2011) Early diagnosis of Werner's syndrome using exome-wide sequencing in a single, atypical patient. Frontiers in Genomic Endocrinology, 2 (Articl).

Rappas, Mathieu, Oliver, Antony W and Pearl, Laurence H (2011) Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1. Nucleic Acids Research, 39 (1). pp. 313-324. ISSN 0305-1048

Rulten, Stuart L, Fisher, Anna E O, Robert, Isabelle, Zuma, Maria C, Rouleau, Michele, Ju, Limei, Poirier, Guy, Reina-San-Martin, Bernardo and Caldecott, Keith W (2011) PARP-3 and APLF function together to accelerate nonhomologous end joining. Molecular Cell, 41 (1). pp. 33-45. ISSN 1097-2765

S

Say, Amanda F, Ledford, LeAnna L, Sharma, Deepti, Singh, Akhilesh K, Leung, Wing-Kit, Sehorn, Hilarie A, Tsubouchi, Hideo, Sung, Patrick and Sehorn, Michael G (2011) The budding yeast Mei5-Sae3 complex interacts with Rad51 and preferentially binds a DNA fork structure. DNA Repair, 10 (6). pp. 586-594. ISSN 1568-7864

Sertic, Sarah, Pizzi, Sara, Cloney, Ross, Lehmann, Alan R, Marini, Federica, Plevani, Paolo and Muzi-Falconi, Marco (2011) Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation. Proceedings of the National Academy of Sciences, 108 (33). pp. 13647-13652. ISSN 1091-6490

Shibata, A, Conrad, S, Birraux, J, Geuting, V, Barton, O, Ismail, A, Kakarougkas, A, Meek, K, Taucher-Scholz, G, Lobrich, M and Jeggo, P (2011) Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO Journal, 30 (6). pp. 1079-1092. ISSN 0261-4189

Slupianek, A, Poplawski, T, Jozwiakowski, Stanislaw, Cramer, K, Pytel, D, Stoczynska, E, Nowicki, MO, Blasiak, J and Skorski, T (2011) BCR/ABL stimulates WRN to promote survival and genomic instability. Cancer Research, 71 (3). pp. 842-851. ISSN 0008-5472

Steere, N, Wagner, M, Beishir, S, Smith, Ewan, Breslin, Claire, Morrison, C.G, Hochegger, Helfrid and Kuriyama, R (2011) Centrosome amplification in CHO and DT40 cells by inactivation of cyclin-dependent kinases. Cytoskeleton, 68 (8). pp. 446-458. ISSN 19493584

T

Tang, Zhaohua, Luca, Maria, Portillio, Jessica, Ngo, Benson, Chang, Cathey, Wen, Teresa, Murray, Johanne and Carr, Antony (2011) LAMMER kinase Kic1 is involved in pre-mRNA processing. Experimental Cell Research, 317 (16). pp. 2308-2320. ISSN 0014-4827

Taylor, Mark, Moore, Karen, Murray, Johanne, Aves, Stephen J and Price, Clive (2011) Mcm10 interacts with Rad4/Cut5(TopBP1) and its association with origins of DNA replication is dependent on Rad4/Cut5(TopBP1). DNA Repair, 10 (11). pp. 1154-63.

Tran, JC, Zamdborg, L, Ahlf, DR, Lee, JE, Catherman, AD, Durbin, KR, Tipton, JD, Vellaichamy, A, Kellie, JF, LI, M, Wu, C, Sweet, Steve, Early, BP, Siuti, N, Leduc, R.D, Compton, P.D, Thomas, PM and Lelleher, N.L (2011) Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature, 480 (7376). pp. 254-258. ISSN 00280836

V

Vejrup-Hansen, Rasmus, Mizuno, Ken'ichi, Miyabe, Izumi, Fleck, Oliver, Holmberg, Christian, Murray, Johanne M, Carr, Antony M and Nielsen, Olaf (2011) Schizosaccharomyces pombe Mms1 channels repair of perturbed replication into Rhp51 independent homologous recombination. DNA Repair, 10 (3). pp. 283-295.

W

Watts, Felicity Z and Hoffmann, Eva (2011) SUMO meets meiosis: an encounter at the synaptonemal complex: SUMO chains and sumoylated proteins suggest that heterogeneous and complex interactions lie at the centre of the synaptonemal complex. BioEssays, 33. pp. 529-33. ISSN 0265-9247

This list was generated on Fri Dec 6 03:18:49 2019 GMT.