Items for Sussex Centre for Genome Damage and Stability in 2008

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Number of items: 53.


Anttinen, Anu, Koulu, Leena, Nikoskelainen, Eeva, Portin, Raija, Kurki, Timo, Erkinjuntti, Matti, Jaspers, Nicolaas G J, Raams, Anja, Green, Michael H L, Lehmann, Alan, Wing, Jonathan F, Arlett, Colin F and Marttila, Reijo J (2008) Neurological symptoms and natural course of xeroderma pigmentosum. Brain, 131 (8). pp. 1979-1989. ISSN 0006-8950

Anttinen, Anu, Koulu, Leena, Nikoskelainen, Eeva, Portin,, Raija, Kurki, Timo, Erkinjuntti,, Matti, Jaspers, Nicolaas G J, Raams, Anja, Green, Michael H L, Lehmann, Alan R, Wing, Jonathan F, Arlett, Colin F and Marttila, Reijo J (2008) Neurological symptoms and natural course of xeroderma pigmentosum. Brain, 131 (8). pp. 1979-1989. ISSN 0006-8950

Arlett, C F, Green, M H L, Rogers, P B, Lehmann, A R and Plowman, P N (2008) Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts. British Journal of Radiology, 81 (961). pp. 51-58. ISSN 0007-1285

Baxter, Jonathan and Diffley, John F X (2008) Topoisomerase II inactivation prevents the completion of DNA replication in budding yeast. Molecular Cell, 30 (6). pp. 790-802. ISSN 1097-2765

Bianchi, Alessandro and Shore, D (2008) How telomerase reaches its end: mechanism of telomerase regulation by the telomeric complex. Molecular Cell, 31 (2). pp. 153-165. ISSN 10972765

Bianchi, Alessandro and Shore, David (2008) Refined view of the ends. Science, 320 (5881). pp. 1301-1302. ISSN 00368075

Brough, Paul A., Pearl, Laurence H., Prodromou, Chrisostomos and et al, (2008) 4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer. Journal of Medicinal Chemistry, 51 (2). pp. 196-218. ISSN 0022-2623

Busygina, Valeria, Sehorn, Michael G, Shi, Idina Y, Tsubouchi, Hideo, Roeder, G Shirleen and Sung, Patrick (2008) Hed1 regulates Rad51-mediated recombination via a novel mechanism. Genes & Development, 22 (6). pp. 786-795. ISSN 0890-9369

Caldecott, Keith (2008) Single-strand break repair and genetic disease. Nature Reviews Genetics, 9 (8). pp. 619-631. ISSN 0028-0836

Caldecott, Keith (2008) Special Issue - DNA damage responses and neurological disease - Preface. DNA Repair, 7 (7). p. 1009. ISSN 15687864

Caldecott, Keith W (2008) Preface. DNA Repair, 7 (7). p. 1009. ISSN 1568-7864

Carballo, Jesús A, Johnson, Anthony L, Sedgwick, Steven G and Cha, Rita S (2008) Phosphorylation of the axial element protein Hop1 by Mec1/Tel1 ensures meiotic interhomolog recombination. Cell, 132 (5). pp. 758-770. ISSN 0092-8674

Catt, Susan, Chalmers, Anthony J. and Fallowfield, Lesley J. (2008) Psychosocial and supportive-care needs in high-grade glioma. Lancet Oncology, 9 (9). pp. 884-891. ISSN 1470-2045

Connell, Claire M, Colnaghi, Rita and Wheatley, Sally P (2008) Nuclear survivin has reduced stability and is not cytoprotective. Journal of Biological Chemistry, 238 (6). pp. 3289-3296. ISSN 0021-9258

Connell, Claire M, Wheatley, Sally P and McNeish, Iain A (2008) Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis. Cancer Research, 68 (19). pp. 7923-7931. ISSN 1538-7445 (Electronic)

Connell, Claire M., Colnaghi, Rita and Wheatley, Sally P. (2008) Nuclear survivin has reduced stability and is not cytoprotective. Journal of Biological Chemistry, 238 (6). pp. 3289-3296. ISSN 0021-9258

Downs, Jessica (2008) Histone H3 K56 acetylation, chromatin assembly, and the DNA damage checkpoint. DNA Repair, 7 (12). pp. 2020-2024. ISSN 1568-7864

Eccles, Suzanne A, Massey, Andy, Raynaud, Florence I, Sharp, Swee Y, Box, Gary, Valenti, Melanie, Patterson, Lisa, de Haven Brandon, Alexis, Gowan, Sharon, Boxall, Frances, Aherne, Wynne, Rowlands, Martin, Hayes, Angela, Martins, Vanessa, Urban, Frederique, Boxall, Kathy, Prodromou, Chrisostomos, Pearl, Laurence, James, Karen, Matthews, Thomas P, Cheung, Kwai-Ming, Kalusa, Andrew, Jones, Keith, McDonald, Edward, Barril, Xavier, Brough, Paul A, Cansfield, Julie E, Dymock, Brian, Drysdale, Martin J, Finch, Harry, Howes, Rob, Hubbard, Roderick E, Surgenor, Alan, Webb, Paul, Wood, Mike, Wright, Lisa and Workman, Paul (2008) NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis. Cancer Research, 68 (8). pp. 2850-2860. ISSN 0008-5472

Goodarzi, Aaron, Noon, Angela T, Deckbar, Dorothee, Ziv, Yael, Shiloh, Yosef, Löbrich, Markus and Jeggo, Penny A (2008) ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Molecular Cell, 31 (2). pp. 167-177. ISSN 1097-2765

Gupta, S K, Sheikh, M A, Islam, M S, Rahman, K S, Jahan, N, Rahman, M M, Hoekstra, R M, Johnston, R, Ram, P K and Luby, S (2008) Usefulness of the hydrogen sulfide test for assessment of water quality in Bangladesh. Journal of Applied Microbiology, 104 (2). pp. 388-395. ISSN 1364-5072

Hawkins, Thomas A, Haramis, Anna-Pavlina, Etard, Christelle, Prodromou, Chrisostomos, Vaughan, Cara K, Ashworth, Rachel, Ray, Saikat, Behra, Martine, Holder, Nigel, Talbot, William S, Pearl, Laurence H, Strähle, Uwe and Wilson, Stephen W (2008) The ATPase-dependent chaperoning activity of Hsp90a regulates thick filament formation and integration during skeletal muscle myofibrillogenesis. Development, 135 (6). pp. 1147-1156. ISSN 0950-1991

Hirota, K, Mizuno, Ken'ichi, Shibata, T and Ohta, K (2008) Distinct Chromatin Modulators Regulate the Formation of Accessible and Repressive Chromatin at the Fission Yeast Recombination Hotspot ade6-M26. Molecular Biology of the Cell, 19 (3). pp. 1162-1173. ISSN 1939-4586

Ip, Stephen C Y, Rass, Ulrich, Blanco, Miguel G, Flynn, Helen R, Skehel, J Mark and West, Stephen C (2008) Identification of Holliday junction resolvases from humans and yeast. Nature, 456 (7220). pp. 357-61. ISSN 0028-0836

Kilkenney, M L, Dore, A, Roe, S M, Nestoras, K, Ho, J, Watts, F Z and Pearl, L (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair. Genes & Development, 22 (15). pp. 2034-2047. ISSN 0890-9369

Kilkenny, Mairi L, Doré, Andrew S, Roe, S Mark, Nestoras, Konstantinos, Ho, Jenny C Y, Watts, Felicity Z and Pearl, Laurence H (2008) Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signalling. Genes & Development, 22 (15). pp. 2034-47. ISSN 0890-9369

Kleijer, Wim J, Laugel, Vincent, Berneburg, Mark, Nardo, Tiziana, Fawcett, Heather, Gratchev, Alexei, Jaspers, Nicolaas G J, Sarasin, Alain, Stefanini, Miria and Lehmann, Alan R (2008) Incidence of DNA repair deficiency disorders in western Europe: Xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. DNA Repair, 7 (5). pp. 744-750. ISSN 1568-7864

Lehmann, Alan R. (2008) XPD structure reveals its secrets. DNA Repair, 7 (11). pp. 1912-1915. ISSN 1568-7864

Luby, S P, Gupta, S K, Sheikh, M A, Johnston, R B, Ram, P K and Islam, M S (2008) Tubewell water quality and predictors of contamination in three flood-prone areas in Bangladesh. Journal of Applied Microbiology, 105 (4). pp. 1002-1008. ISSN 1364-5072

Millson, Stefan H, Vaughan, Cara K, Zhai, Chao, Ali, Maruf M U, Panaretou, Barry, Piper, Peter W, Pearl, Laurence H and Prodromou, Chrisostomos (2008) Chaperone ligand-discrimination by the TPR-domain protein Tah1. Biochemical Journal, 413. pp. 261-268. ISSN 0264-6021

Murray, Johanne M and Carr, Antony M (2008) Smc5/6: a link between DNA repair and unidirectional replication? Nature Reviews Molecular Cell Biology, 9. pp. 177-182. ISSN 1471-0072

Niimi, Atsuko, Brown, Stephanie, Sabbioneda, Simone, Kannouche, Patricia L., Scott, Andrew, Yasui, Akira, Green, Catherine M. and Lehmann, Alan R. (2008) Regulation of proliferating cell nuclear antigen ubiquitination in mammalian cells. Proceedings of the National Academy of Sciences, 105 (42). pp. 16125-16130. ISSN 0027-8424

O'Driscoll, Mark (2008) Haploinsufficiency of DNA damage response genes and their potential influence in human genomic disorders. Current Genomics, 9 (3). pp. 137-146. ISSN 1389-2029

O'Driscoll, Mark (2008) TREX1 DNA exonuclease deficiency, accumulation of single stranded DNA and complex human genetic disorders. DNA Repair, 7 (6). pp. 997-1003. ISSN 1568-7864

O'Driscoll, Mark and Jeggo, Penny (2008) CsA can induce DNA double-strand breaks: implications for BMT regimens particularly for individuals with defective DNA repair. Bone Marrow Transplantation, 41 (11). pp. 983-989. ISSN 0268-3369

O'Driscoll, Mark and Jeggo, Penny (2008) The role of the DNA damage response pathways in brain development and microcephaly: insight from human disorders. DNA Repair, 7 (7). pp. 1039-1050. ISSN 15687864

Offman, Judith, Jina, Nipurna, Theron, Therina, Pallas, Jacky, Hubank, Mike and Lehmann, Alan (2008) Transcriptional changes in trichothiodystrophy cells. DNA Repair, 7 (8). pp. 1364-1371. ISSN 1568-7864

Pearl, Laurence H, Prodromou, Chrisostomos and Workman, Paul (2008) The Hsp90 molecular chaperone: an open and shut case for treatment. Biochemical Journal, 410. pp. 439-453. ISSN 0264-6021

Petermann, Eva, Helleday, Thomas and Caldecott, Keith W (2008) Claspin promotes normal replication fork rates in human cells. Molecular Biology of the Cell, 19 (6). pp. 2373-2378. ISSN 1059-1524

Pike, Ashley C W, Rellos, Peter, Niesen, Frank H, Turnbull, Andrew, Oliver, Antony W, Parker, Sirlester A, Turk, Benjamin E, Pearl, Laurence H and Knapp, Stefan (2008) Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites. EMBO Journal, 27 (4). pp. 704-714. ISSN 0261-4189

Puglisi, Andrea, Bianchi, Alessandro, Lemmens, Laure, Damay, Pascal and Shore, David (2008) Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition. EMBO Journal, 27 (17). pp. 2328-2339. ISSN 0261-4189

Rass, Ulrich, Ahel, Ivan and West, Stephen C (2008) Molecular mechanism of DNA deadenylation by the neurological disease protein aprataxin. The Journal of Biological Chemistry, 283 (49). pp. 33994-34001. ISSN 0021-9258

Rulten, Stuart L, Cortes-Ledesma, Felipe, Guo, Liandi, Iles, Natasha J and Caldecott, Keith W (2008) APLF (C2orf13) is a novel component of poly(ADP-ribose) signaling in mammalian cells. Molecular and Cellular Biology, 28 (14). pp. 4620-4628. ISSN 0270-7306

Sabbioneda, Simone, Gourdin, Audrey M, Green, Catherine M, Zotter, Angelika, Giglia-Mari, Giuseppina, Houtsmuller, Adriaan, Vermeulen, Wim and Lehmann, Alan R (2008) Effect of proliferating cell nuclear antigen ubiquitination and chromatin structure on the dynamic properties of the Y-family DNA polymerases. Molecular Biology of the Cell, 19 (12). pp. 5193-5202. ISSN 1939-4586

Sheikh, Md Arif, Potter, Jane A, Johnson, Kenneth A, Sim, Robert B, Boyd, E Fidelma and Taylor, Garry L (2008) Crystal structure of VC1805, a conserved hypothetical protein from a Vibrio cholerae pathogenicity island, reveals homology to human p32. Proteins: Structure, Function, and Bioinformatics, 71 (3). pp. 1563-1571. ISSN 0887-3585

Stiff, Thomas, Cerosaletti, K, Concannon, P, O'Driscoll, Mark and Jeggo, Penny (2008) Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1. Human Molecular Genetics, 17 (20). pp. 3247-3253. ISSN 09646906

Taylor, Elaine M, Copsey, Alice C, Hudson, Jessica J, Vidot, Susanne and Lehmann, Alan R (2008) Identification of the proteins, including MAGEG1, that make up the human SMC5-6 protein complex. Molecular and Cellular Biology, 28 (4). pp. 1197-1206. ISSN 0270-7306

Tsang, Ellen and Carr, Antony M (2008) Replication fork arrest, recombination and the maintenance of ribosomal DNA stability. DNA Repair, 7 (10). pp. 1613-1623. ISSN 1568-7864

Vaughan, Cara K, Mollapour, Mehdi, Smith, Jennifer R, Truman, Andrew, Hu, Bin, Good, Valerie M, Panaretou, Barry, Neckers, Len, Clarke, Paul A, Workman, Paul, Piper, Peter W, Prodromou, Chrisostomos and Pearl, Laurence H (2008) Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. Molecular Cell, 31 (6). pp. 886-895. ISSN 1097-2765

Wrzesinski, J and Jozwiakowski, Stanislaw (2008) Structural basis for recognition of Co2+ by RNA aptamers. FEBS Journal, 275 (8). pp. 1651-1662. ISSN 1742-464X

Yamada, K, Hirota, K, Mizuno, Ken'ichi, Shibata, Atsushi and Ohta, K (2008) Essential roles of Snf21, a Swi2/Snf2 family chromatin remodeler, in fission yeast mitosis. Genes & Genetic Systems, 83 (5). pp. 361-372. ISSN 1880-5779

Zhang, Minghao, Botër, Marta, Li, Kuoyu, Kadota, Yasuhiro, Panaretou, Barry, Prodromou, Chrisostomos, Shirasu, Ken and Pearl, Laurence H (2008) Structural and functional coupling of Hsp90- and Sgt1-centred multi-protein complexes. EMBO Journal, 27 (20). pp. 2789-2798. ISSN 0261-4189

Conference or Workshop Item

Walliser, C, Retlich, M, Wollny, C, Harris, R, Everett, K L, Josephs, M B, Roe, S M, Vatter, P, Christow, C, Rodrigues-Lima, F, Pearl, L H, Driscoll, P C, Katan, M, Gierschik, P and Bunney, T D (2008) Rac2 regulates its effector phospholipase C-gamma 2 through interaction with a split PH domain. In: 49th Annual Meeting German-Society-for-Experimental-and-Clinical-Pharmacology-and-Toxicology, Mainz, GERMANY.


Cancer Research Technology Ltd; Collins, Ian; Caldwell, John J; Oliver, Antony W; Raynham, Tony M; Welsh, Emma J; Matijssen, Cornelius A J (2008) Therapeutic oxy-phenyl-aryl compounds and their use. PCT/GB2008/003586.

This list was generated on Thu Jan 26 11:40:00 2023 GMT.