Article

Caldecott, Keith (2003) Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions. DNA Repair, 2 (10). pp. 1087-1100. ISSN 1568-7864

Caldecott, Keith (2003) Cell signaling: The BRCT domain: signaling with friends? Science, 302 (5645). pp. 579-580. ISSN 0036-8075

Caldecott, Keith (2003) DNA single-strand break repair and spinocerebellar ataxia. Cell, 112 (1). pp. 7-10. ISSN 0092-8674

Caldecott, Keith (2003) XRCC1 and DNA strand break repair. DNA Repair, 2 (9). pp. 955-969. ISSN 1568-7864

Caldecott, Keith (2003) A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage. Nucleic Acids Research, 31 (19). pp. 5526-5533. ISSN 0305-1048

Carvalho, Ana, Carmena, Mar, Sambade, Clara, Earnshaw, William C and Wheatley, Sally P (2003) Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. Journal of Cell Science, 116 (14). pp. 2987-2998. ISSN 0021-9533

Dai, Y, Kysela, B, Hanakahi, L A, Manolis, K, Riballo, E, Stumm, M, Harville, T O, West, S C, Oettinger, M A and Jeggo, P A (2003) Non-homologous end joining and V(D)J recombination require an additional factor. Proceedings of the National Academy of Sciences, 100 (5). pp. 2462-2467. ISSN 1091-6490

Dionne, Isabelle, Nookala, Ravi K, Jackson, Stephen P, Doherty, Aidan J and Bell, Stephen D (2003) The heterotrimeric PCNA of the hyperthermophilic archaeon Sulfolobus solfatricus: implications for the clamp loading mechanism. Molecular Cell, 11 (1). pp. 275-282. ISSN 1097-2765

Doherty, Aidan, Kysela, Boris, Jeggo, Penny, Iwabuchi, K, Basu, BP and Kurihara, T (2003) p53-binding protein 1 (53BP1) binds to DNA at IR damage-induced foci and promotes DNA double-strand break repair. Journal of Biological Chemistry, 278. pp. 36487-36495. ISSN 0021-9258

Downs, Jessica A, Kosmidou, Effie, Morgan, Alan and Jackson, Stephen P (2003) Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. Molecular Cell, 11 (6). pp. 1685-1692. ISSN 1097-2765

Foray, Nicolas, Marot, Didier, Gabriel, Anastasia, Randrianarison, Voahangy, Carr, Antony M, Perricaudet, Michel, Ashworth, Alan and Jeggo, Penny (2003) A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein. EMBO Journal, 22 (11). pp. 2860-2871. ISSN 0261-4189

Gennery, A R and O'Driscoll, M (2003) Unravelling the web of DNA repair disorders. Clinical and Experimental Immunology, 134 (3). pp. 385-387. ISSN 0009-9104

Henry-Mowatt, Judith, Jackson, Dean, Masson, Jean-Yves, Johnson, Penny A, Clements, Paula M, Benson, Fiona E, Thompson, Larry H, Takeda, Shunichi, West, Stephen C and Caldecott, Keith W (2003) XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Molecular Cell, 11 (4). pp. 1109-1117. ISSN 1097-2765

Hinks, J, Roe, Mark, Ho, J C, Watts, Felicity, Phelan, J, McAllister, M and Pearl, Laurence (2003) Expression, purification and preliminary X-ray analysis of the BRCT domain from Rhp9/Crb2. Acta Crystallographica Section D: Biological Crystallography, 59 (Pt 7). 1230-1233.. ISSN 0907-4449

Ho, J C and Watts, Felicity (2003) Characterisation of SUMO conjugating enzyme mutants in Schizosaccharomyces pombe identifies a dominant negative allele which severely reduces SUMO conjugation. Biochemical Journal, 21. ISSN 0264-6021

Hoffmann, Eva R, Shcherbakova, Polina V, Kunkel, Thomas A and Borts, Rhona H (2003) MLH1 Mutations Differentially Affect Meiotic Functions in Saccharomyces cerevisiae. Genetics, 163 (2). pp. 515-526. ISSN 0016-6731

Hughes-Davies, Luke, Huntsman, David, Ruas, Margarida, Fuks, Francois, Bye, Jacqueline, Chin, Suet-Feung, Milner, Jonathon, Brown, Lindsay A, Hsu, Forrest, Gilks, Blake, Nielsen, Torsten, Schulzer, Michael, Chia, Stephen, Ragaz, Joseph, Cahn, Anthony, Linger, Lori, Ozdag, Hilal, Cattaneo, Elena, Jordanova, E S, Schuuring, Edward, Yu, David S, Venkitaraman, Ashok, Ponder, Bruce, Doherty, Aidan, Aparicio, Samuel, Bentley, David, Theillet, Charles, Ponting, Chris P, Caldas, Carlos and Kouzarides, Tony (2003) EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell, 115 (5). pp. 523-535. ISSN 0092-8674

Iwabuchi, Kuniyoshi, Basu, Balaka Piku, Kysela, Boris, Kurihara, Takayuki, Shibata, Masao, Guan, Deyu, Cao, Yongheng, Hamada, Tomio, Imamura, Kouji, Jeggo, Penny A, Date, Takayasu and Doherty, Aidan J (2003) Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. Journal of Biological Chemistry, 278 (38). pp. 36487-36495. ISSN 0021-9258

Kannouche, Patricia, Fernández de Henestrosa, Antonio R, Coull, Barry, Vidal, Antonio E, Gray, Colin, Zicha, Daniel, Woodgate, Roger and Lehmann, Alan R (2003) Localization of DNA polymerases η and ι to the replication machinery is tightly co-ordinated in human cells. EMBO Journal, 22 (5). pp. 1223-1233. ISSN 0261-4189

Kysela, Boris, Doherty, Aidan J, Chovanec, Miroslav, Stiff, Thomas, Ameer-Beg, Simon M, Vojnovic, Borivoj, Girard, Pierre-Marie and Jeggo, Penny A (2003) Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule. Journal of Biological Chemistry, 278 (25). pp. 22466-22474. ISSN 0021-9258

Laursen, Louise V, Ampatzidou, Eleni, Andersen, Anni H and Murray, Johanne M (2003) Role for the fission yeast RecQ helicase in DNA repair in G2. Molecular and Cellular Biology, 23 (10). pp. 3692-3705. ISSN 0270-7306

Laursen, Louise V, Bjergbaek, Lotte, Murray, Johanne M and Andersen, Anni H (2003) RecQ helicases and topoisomerase III in cancer and aging. Biogerontology, 4 (5). pp. 275-87. ISSN 1573-6768

Lehmann, Alan (2003) Low-fidelity DNA polymerases. Current Biology, 13 (15). R585-R585. ISSN 1362-4962

Lehmann, Alan R (2003) Replication of Damaged DNA. Cell Cycle, 2 (4). pp. 299-301. ISSN 1538-4101

Lehmann, Alan R. (2003) DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. Biochimie, 85 (11). pp. 1101-1111. ISSN 0300-9084

Liu, Cong, Powell, Kelly A, Mundt, Kirsten, Wu, Le-Jung, Carr, Antony M and Caspari, Thomas (2003) Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. Genes & Development, 17 (9). pp. 1130-1140. ISSN 0890-9369

Nakamura, Jun, Asakura, Shoji, Hester, Susan D, de Murcia, Gilbert, Caldecott, Keith W and Swenberg, James A (2003) Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time. Nucleic Acids Research, 31 (17). e104-e104. ISSN 0305-1048

O'Driscoll, M, Ruiz-Peres, V L, Woods, C G, Jeggo, P A and Goodship, J A (2003) A splicing mutation affecting expression of ataxia-telangiectasis and Rad3-related protein (ATR) results in Seckel syndrome. Nature Genetics, 33. pp. 497-501.

O'Driscoll, Mark and Jeggo, Penny A (2003) Clinical impact of ATR checkpoint signalling failure in humans. Cell Cycle, 2 (3). pp. 194-195.

Okano, Satoshi, Lan, Li, Caldecott, Keith W, Mori, Toshio and Yasui, Akira (2003) Spatial and temporal cellular responses to single-strand breaks in human cells. Molecular and Cellular Biology, 23 (11). pp. 3974-3981. ISSN 1098-5549

Pemberton, Trevor J, Rulten, Stuart L and Kay, John E (2003) Identification and characterisation of Schizosaccharomyces pombe cyclophilin 3 and its human homologue cyclophilin 20. Journal of Chromatography B, 786 (1-2). pp. 81-91. ISSN 1570-0232

Rünger, Thomas M, Kotas, Markus, Poot, Martin, Leverkus, Martin, Epe, Bernd, Jeggo, Penny and Hellfritsch, Doris (2003) Reduced joining of DNA ends correlates with chromosomal instability in three melanoma cell lines. Tumor Biology, 24 (2). pp. 100-108. ISSN 1010-4283

Smith, Julianne, Riballo, Enriqueta, Kysela, B, Baldeyron, Celine, Manolis, Kostas, Masson, Christel, Lieber, Michael R, Papadopoulo, Dora and Jeggo, Penny (2003) Impact of DNA ligase IV on the fidelity of end joining in human cells. Nucleic Acids Research, 31 (8). pp. 2157-2167. ISSN 0305-1048

Stary, Anne, Kannouche, Patricia, Lehmann, Alan R and Sarasin, Alain (2003) Role of DNA Polymerase η in the UV Mutation Spectrum in Human Cells. Journal of Biological Chemistry, 278 (21). pp. 18767-18775. ISSN 0021-9258

Werler, Petra J H, Hartsuiker, Edgar and Carr, Antony M (2003) A simple Cre-loxP method for chromosomal N-terminal tagging of essential and non-essential Schizosaccharomyces pombe genes. Gene, 304. pp. 133-141. ISSN 0378-1119

d'Adda di Fagagna, Fabrizio, Weller, Geoffrey R, Doherty, Aidan J and Jackson, Stephen P (2003) The Gam protein of phage Mu is an orthologue of eukaryotic Ku. EMBO Reports, 4 (1). pp. 47-52. ISSN 1469-221X

Book Section

Fousteri, Maria I and Lehmann, Alan R (2003) Xeroderma Pigmentosum. In: Hisama, Fuki M, Weissman, Sherman M and Martin, George M (eds.) Chromosomal Instability and Aging: Basic Science and Clinical Implications. Marcel Dekker, New York, pp. 409-439. ISBN 0824708563

Goodarzi, Aaron, Block, WD and Lees-Miller, SP (2003) The roles of ATM and ATR in DNA damage-induced cell cycle control. In: Meijer, L, Mezequel, J and Roberge, M (eds.) Progress in Cell Cycle Research Volume 5: Cell Cycle Regulators as Therapeutic Targets. Life in Progress Editions, France.