A

Alard, Emilie, Butnariu, Aura-Bianca, Grillo, Marta, Kirkham, Charlotte, Zinovkin, Dmitry Aleksandrovich, Newnham, Louise, Macciochi, Jenna and Pranjol, Md Zahidul Islam (2020) Advances in anti-cancer immunotherapy: car-T cell, checkpoint inhibitors, dendritic cell vaccines, and oncolytic viruses, and emerging cellular and molecular targets. Cancers, 12 (7). a1826. ISSN 2072-6694

B

Baden, Tom, Maina, Mahmoud Bukar, Maia Chagas, Andre, Mohammed, Yunusa Garba, Auer, Thomas O, Silbering, Ana, von Tobel, Lukas, Pertin, Marie, Hartig, Renee, Aleksic, Jelena, Akinrinade, Ibukun, Awadelkareem, Mosab A, Koumoundourou, Artemis, Jones, Aled, Arieti, Fabiana, Beale, Andrew, Münch, Daniel, Salek, Samyra Cury, Yusuf, Sadiq and Prieto-Godino, Lucia L (2020) TReND in Africa: toward a truly global (neuro)science community. Neuron, 107. pp. 1-5. ISSN 0896-6273

Barqawi, Aminah (2020) Understanding the nature of specificity of Bacillus thuringiensis Cry2A toxins against Plutella xylostella. Doctoral thesis (PhD), University of Sussex.

Biasetti, Luca (2020) Characterising the effects of genetic risk factors of Alzheimer’s disease on synaptic transmission: a functional and structural analysis. Doctoral thesis (PhD), University of Sussex.

Bradshaw, Daniel, Gilleece, Yvonne, Verma, Sumita, Abramowicz, Iga, Bremner, Stephen and Perry, Nicky (2020) Protocol for a phase IV, open-label feasibility study investigating non-invasive markers of hepatic fibrosis in people living with HIV-1 and non-alcoholic fatty liver disease randomised to receiving optimised background therapy (OBT) plus maraviroc or OBT alone. BMJ Open, 10. a035596 1-9. ISSN 2044-6055

C

Collins, Richard, Ojea, Maria Jose Heras, Mansikkamaki, Akseli, Tang, Jinkui and Layfield, Richard A (2020) Carbonyl back-bonding influences the rate of quantum tunnelling in a dysprosium metallocene single-molecule magnet. Inorganic Chemistry, 59 (1). pp. 642-647. ISSN 0020-1669

D

Danahay, H, Fox, R, Lilley, S, Charlton, H, Adley, K, Christie, L, Ansari, E, Ehre, C, Flen, A, Tuvim, M J, Dickey, B F, Williams, C, Beaudoin, S, Collingwood, S P and Gosling, M (2020) Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction. FASEB BioAdvances, 2. pp. 464-477. ISSN 2573-9832

Danahay, Hannah L, Lilley, Sarah, Fox, Roy, Charlton, Holly, Sabater, Juan, Button, Brian, McCarthy, Clive, Collingwood, Stephen P and Gosling, Martin (2020) TMEM16A potentiation: a novel therapeutic approach for the treatment of cystic fibrosis. American Journal of Respiratory and Critical Care Medicine, 201 (8). pp. 946-954. ISSN 1073-449X

Ditsiou, Angeliki (2020) Targeting breast cancer via LMTK3 inhibition: from structural and functional studies to the discovery and preclinical testing of the first LMTK3 small molecule inhibitor. Doctoral thesis (PhD), University of Sussex.

Ditsiou, Angeliki, Cilibrasi, Chiara, Simigdala, Nikiana, Harris, Leanne, Vella, Viviana, Gagliano, Teresa, Iachini, Maria Chiara, Simon, Thomas, Zhou, Lihong, Hassell-Hart, Storm, Pearl, Laurence H, Roe, S Mark, Spencer, John, Prodromou, Chrisostomos, Giamas, Georgios and others, (2020) The structure-function relationship of oncogenic LMTK3. Science Advances, 6 (46). pp. 1-19. ISSN 2375-2548

G

Gagliano, Teresa, Shah, Kalpit, Gargani, Sofia, Lao, Liyan, Alsaleem, Mansour, Chen, Jianing, Ntafis, Vasileios, Huang, Penghan, Ditsiou, Angeliki, Vella, Viviana, Yadav, Kritika, Bienkowska, Kamila, Benstead-Hum, Graeme, Pearl, Frances M G, Giamas, Georgios and others, (2020) PIK3Cδ expression by fibroblasts promotes triple-negative breast cancer progression. Journal of Clinical Investigation, 130 (6). pp. 3188-3204. ISSN 0021-9738

Giamas, Georgios (2020) [Editorial] Cancer gene therapy: vision and strategy for the new decade. Cancer Gene Therapy, 27. p. 115. ISSN 0929-1903

Giamas, Georgios (2020) Reviewer recognition. Cancer gene therapy, 27. a264. ISSN 0929-1903

Goje, Lazarus Joseph, Elmi, Elmi Dahir, Bracuti, Anthony, Courty, Thomas, Rao, Tejas, Alzahrani, Faisal Ay and Crickmore, Neil (2020) Identification of Aedes aegypti specificity motifs in the N-terminus of the Bacillus thuringiensis Cry2Aa pesticidal protein. Journal of Invertebrate Pathology, 174. a107423 1-5. ISSN 0022-2011

Guo, Zhaojiang, Kang, Shi, Sun, Dan, Gong, Lijun, Zhou, Junlei, Qin, Jianying, Guo, Le, Zhu, Liuhong, Bai, Yang, Ye, Fan, Wu, Qingjun, Wang, Shaoli, Crickmore, Neil, Zhou, Xuguo and Zhang, Youjun (2020) MAPK-dependent hormonal signaling plasticity contributes to overcoming Bacillus thuringiensis toxin action in an insect host. Nature Communications, 11. a3003 1-14. ISSN 2041-1723

H

Harries, Rhiannon W, Brown, Christopher J, Ogilvie, Sean P, Large, Matthew J, Amorim Graf, Aline, Clifford, Keiran, Simon, Thomas, Giamas, Georgios, Dalton, Alan B and King, Alice A K (2020) Langmuir films of layered nanomaterials: edge interactions and cell culture applications. Journal of Physical Chemistry B. ISSN 1520-5207

K

Karia, Dimple, Gilbert, Robert C G, Biasutto, Antonio J, Porcher, Catherine and Mancini, Erika J (2020) The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain. Royal Society Open Science, 7 (1). ISSN 2054-5703

L

Lassalle, Damien, Tetreau, Guillaume, Pinaud, Silvain, Galinier, Richard, Crickmore, Neil, Gourbal, Benjamin and Duval, David (2020) Glabralysins, potential New β-pore-forming toxin family members from the schistosomiasis vector snail biomphalaria glabrata. Genes, 11 (65). pp. 1-17. ISSN 2073-4425

M

Maina, Mahmoud B, Burra, Gunasekhar, Al-Hilaly, Youssra, Mengham, Kurtis, Fennell, Kate and Serpell, Louise C (2020) Metal- and UV- catalyzed oxidation results in trapped amyloid-β intermediates revealing that self-assembly is required for Aβ-induced cytotoxicity. iScience, 23 (10). a101537. ISSN 2589-0042

Marshall, Karen E, Vadukul, Devkee M, Staras, Kevin and Serpell, Louise C (2020) Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway. Cellular and Molecular Life Sciences, 77. pp. 5031-5043. ISSN 1420-682X

Martelli, Costanza, King, Alice, Simon, Thomas and Giamas, Georgios (2020) Graphene-induced transdifferentiation of cancer stem cells as a therapeutic strategy against glioblastoma. ACS Biomaterials Science & Engineering. ISSN 2373-9878

Milton-Harris, Leanne, Jeeves, Mark, Walker, Sarah A, Ward, Simon E and Mancini, Erika J (2020) Small molecule inhibits T-cell acute lymphoblastic leukaemia oncogenic interaction through conformational modulation of LMO2. Oncotarget, 11. pp. 1737-1748. ISSN 1949-2553

N

Navti, Beryl Bongkwati (2020) Living with dementia in care homes: the nature, role, and impact of pharmaceutical care provision by community pharmacists. Doctoral thesis (PhD), University of Sussex.

Noble, James William (2020) The biological and pharmacological allosteric modulation of inositol monophosphatase. Doctoral thesis (PhD), University of Sussex.

O

Oakley, Sebastian S, Maina, Mahmoud B, Marshall, Karen E, Al-Hilaly, Youssra K, Harrington, Charlie R, Wischik, Claude M and Serpell, Louise C (2020) Tau filament self-assembly and structure: tau as a therapeutic target. Frontiers in Neurology, 11. p. 590754. ISSN 1664-2295

P

Paladino, Antonella, Woodford, Mark R, Backe, Sarah J, Sager, Rebecca A, Kancherla, Priyanka, Daneshvar, Michael A, Chen, Victor Z, Bourboulia, Dimitra, Ahanin, Elham F, Prodromou, Chrisostomos, Bergamaschi, Greta, Strada, Alessandro, Cretich, Marina, Gori, Alessandro, Veronesi, Marina, Bandiera, Tiziano, Vanna, Renzo, Bratslavsky, Gennady, Serapian, Stefano A, Mollapour, Mehdi and Colombo, Giorgio (2020) Chemical perturbation of oncogenic protein folding: from the prediction of locally unstable structures to the design of disruptors of Hsp90-Client interactions. Chemistry - A European Journal, 26 (43). pp. 9459-9465. ISSN 0947-6539

Piepoli, Sofia, Alt, Aaron Oliver, Atilgan, Canan, Mancini, Erika Jazmin and Erman, Batu (2020) Structural analysis of the PATZ1 BTB domain homodimer. Acta Crystallographica Section D: Structural Biology, 76. pp. 581-593. ISSN 2059-7983

Pollack, Saskia j, Trigg, Jasmine, Khanom, Tahmida, Biasetti, Luca, Marshall, Karen E, Al-Hilaly, Youssra K, Rickard, Janet E, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2020) Paired helical filament-forming region of tau (297–391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells. Journal of Molecular Biology, 432 (17). pp. 4891-4907. ISSN 0022-2836

R

Rajabnezhad, Saeid, Ghafourian, Taravat, Rajabi-Siahboomi, Ali, Missaghi, Shahrzad, Naderi, Majid, Salvage, Jonathan P and Nokhodchi, Ali (2020) Investigation of water vapour sorption mechanism of starch-based pharmaceutical excipients. Carbohydrate Polymers, 238. a116208. ISSN 0144-8617

S

Sacristan-Reviriego, Almudena, Mai Le, Hoang, Georgiou, Michalis, Meunier, Isabelle, Bocquet, Beatrice, Roux, Anne-Françoise, Prodromou, Chrisostomos, Bainbridge, James, Michaelides, Michel and Spuy, Jacqueline van der (2020) Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration. Scientific Reports, 10 (1). a17520 1-15. ISSN 2045-2322

Santha, Miklos, Durham, Heather D, Vigh, Laszlo and Prodromou, Chrisostomos (2020) Editorial: the role of heat shock proteins in neuroprotection. Frontiers in Pharmacology, 11 (a1227). pp. 1-2. ISSN 1663-9812

Shah, Kalpit, Gagliano, Teresa, Garland, Lisa, O’Hanlon, Timothy, Bortolotti, Daria, Gentili, Valentina, Rizzo, Roberta, Giamas, Georgios and Dean, Michael (2020) Androgen receptor signaling regulates the transcriptome of prostate cancer cells by modulating global alternative splicing. Oncogene. ISSN 0950-9232

Simon, Thomas, Jackson, Ellen and Giamas, Georgios (2020) Breaking through the glioblastoma micro-environment via extracellular vesicles. Oncogene. pp. 1-14. ISSN 0950-9232

Simon, Thomas, Kumaran, Anish, Veselu, Diana-Florentina and Giamas, Georgios (2020) Three method-combination protocol for improving purity of extracellular vesicles. International Journal of Molecular Sciences, 21 (9). a3071. ISSN 1661-6596

T

Tabish, Tanveer A, Pranjol, Md Zahidul I, Whatmore, Jacqueline L and Zhang, Shaowei (2020) Status and future directions of anti-metastatic cancer nanomedicines for the inhibition of cathepsin L. Frontiers in Nanotechnology, 2 (a1). pp. 1-10. ISSN 2673-3013

Tareque, Raysa Kahn, Hassell-Hart, Storm, Krojer, Tobias, Bradley, Anthony, Velupillai, Srikannathasan, Talon, Romain, Fairhead, Michael, Day, Iain J, Bala, Kamlesh, Felix, Robert, Kemmitt, Paul, Brennan, Paul, von Delft, Frank, Díaz Sáez, Laura, Spencer, John and Huber, Kilian (2020) Deliberately losing control of C-H activation processes in the design of small molecule fragment arrays targeting peroxisomal metabolism. ChemMedChem. ISSN 1860-7179

Towler, Benjamin P, Pashler, Amy L, Haime, Hope J, Przybyl, Katarzyna M, Viegas, Sandra C, Matos, Rute G, Morley, Simon J, Arraiano, Cecilia M and Newbury, Sarah F (2020) Dis3L2 regulates cell proliferation and tissue growth though a conserved mechanism. PLOS Genetics, 16 (12). a1009297 1-29. ISSN 1553-7390

V

Vadukul, Devkee M, Maina, Mahmoud, Franklin, Hannah, Nardecchia, Astrid, Serpell, Louise C and Marshall, Karen E (2020) Internalisation and toxicity of amyloid-β 1-42 are influenced by its conformation and assembly state rather than size. FEBS Letters, 594 (21). pp. 3490-3503. ISSN 0014-5793

Veenstra, Hildegonda F (2020) Investigating the deregulation of host cell genes by Epstein-Barr virus nuclear antigens. Doctoral thesis (PhD), University of Sussex.

Visic, Petra (2020) The role of the Sigma1 receptor (σ1R) in Store-operated calcium entry (SOCE) microdomains. Doctoral thesis (PhD), University of Sussex.

Y

Young, Luke, Rosell-Hidalgo, Alicia, Inaoka, Daniel Ken, Xu, Fei, Albury, Mary, May, Benjamin, Kita, Kiyoshi and Moore, Anthony L (2020) Kinetic and structural characterisation of the ubiquinol-binding site and oxygen reduction by the trypanosomal alternative oxidase. BBA - Bioenergetics, 1861 (10). a148247. ISSN 0005-2728

Z

Zagorac, Sladjana, de Giorgio, Alex, Dabrowska, Aleksandra, Kalisz, Mark, Casas-Vila, Nuria, Cathcart, Paul, Yiu, Angela, Ottaviani, Silvia, Degani, Neta, Lombardo, Ylenia, Tweedie, Alistair, Nissan, Tracy, Vance, Keith W, Ulitsky, Igor, Stebbing, Justin and Castellano, Leandro (2020) SCIRT lncRNA restrains tumorigenesis by opposing transcriptional programs of tumor-initiating cells. Cancer Research. ISSN 0008-5472