A

Al-Hilaly, Youssra K, Williams, Thomas L, Stewart-Parker, Maris, Ford, Lenzie, Skaria, Eldhose, Cole, Michael, Bucher, William, Morris, Kyle L, Sada, Alaa, Thorpe, Julian R and Serpell, Louise C (2013) A central role for dityrosine crosslinking of Amyloid-β in Alzheimer’s disease. Acta Neuropathologica Communications, 1 (83). pp. 1-17. ISSN 2051-5960

Alcantara, Diana (2013) Understanding at the molecular level the consequences of defective ATR signalling in humans. Doctoral thesis (PhD), University of Sussex.

B

Bartlett, Edward J (2013) Structural and functional characterisation of the Nonhomologous End-­‐Joining proteins of the archaeon Methanocella Paludicola. Doctoral thesis (PhD), University of Sussex.

Beebe, Kristin, Mollapour, Mehdi, Scroggins, Bradley, Prodromou, Chrisostomos, Xu, Wanping, Tokita, Mari, Taldone, Tony, Pullen, Lester, Zierer, Bettina K, Lee, Min-Jung, Trepel, Jane, Buchner, Johannes, Bolon, Daniel, Chiosis, Gabriela and Neckers, Leonard (2013) Post-translational modification and conformational state of Heat Shock Protein 90 differentially affect binding of chemically diverse small molecule inhibitors. Oncotarget, 4. pp. 1065-1074. ISSN 1949-2553

Bianchi, Julie (2013) Investigating the role of a novel primase-polymerase, PrimPol, in DNA damage tolerance in vertebrate cells. Doctoral thesis (PhD), University of Sussex.

Boruah, Bhargavi M., Liu, Dawei, Ye, Duan, Gu, Tie-jun, Jiang, Chun-lai, Qu, Mingsheng, Wright, Edward, Wang, Wei, He, Wen, Liu, Changzhen and Gao, Bin (2013) Single domain antibody multimers confer protection against rabies infection. PLoS ONE, 8 (8). e71383 1-10. ISSN 1932-6203

Both, Leonard, Banyard, Ashley C, van Dolleweerd, Craig, Wright, Edward, Ma, Julian K C and Fooks, Anthony R (2013) Monoclonal antibodies for prophylactic and therapeutic use against viral infections. Vaccine, 31 (12). pp. 1553-1559. ISSN 0264410X

Both, Leonard, van Dolleweerd, Craig, Wright, Edward, Banyard, Ashley C, Bulmer-Thomas, Bianca, Selden, David, Altmann, Friedrich, Fooks, Anthony R and Ma, Julian K C (2013) Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans. The FASEB Journal, 27 (5). pp. 2055-2065. ISSN 0892-6638

C

Carroll, Jean (2013) Investigating aprataxin function: roles in DNA single strand break repair and functional cellular effects. Doctoral thesis (PhD), University of Sussex.

Castellano, Leandro and Stebbing, Justin (2013) Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues. Nucleic Acids Research, 41 (5). pp. 3339-3351. ISSN 0305-1048

Clemens, Michael J, Elia, Androulla and Morley, Simon J (2013) Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibition. PLoS ONE, 8 (8). e71138. ISSN 1932-6203

Cohen, Yifat, Megyeri, Márton, Chen, Oscar C W, Condomitti, Giuseppe, Riezman, Isabelle, Loizides-Mangold, Ursula, Abdul-Sada, Alaa, Rimon, Nitzan, Riezman, Howard, Platt, Frances M, Futerman, Anthony H and Schuldiner, Maya (2013) The yeast P5 type ATPase, Spf1, regulates manganese transport into the endoplasmic reticulum. PLoS ONE, 8 (12). e85519. ISSN 1932-6203

Coldwell, Mark J, Cowan, Joanne L, Vlasak, Markete, Mead, Abbie, Willett, Mark, Perry, Lisa S and Morley, Simon J (2013) Phosphorylation of eIF4GII and 4E-BP1 in response to nocodazole treatment: a reappraisal of translation initiation during mitosis. Cell Cycle, 12 (23). pp. 3615-3628. ISSN 1538-4101

D

Duan, Wei (2013) Cell impedance of cancer cells: towards novel diagnostic and therapeutic selection methods. Masters thesis (MPhil), University of Sussex.

E

El Omari, Kamel, Hoosdally, Sarah J, Tuladhar, Kapil, Karia, Dimple, Hall-Ponselé, Elisa, Platonova, Olga, Vyas, Paresh, Patient, Roger, Porcher, Catherine and Mancini, Erika J (2013) Structural basis for LMO2-driven recruitment of the SCL: E47bHLH heterodimer to hematopoietic-specific transcriptional targets. Cell Reports, 4 (1). pp. 135-147. ISSN 2211-1247

El Omari, Kamel, Meier, Christoph, Kainov, Denis, Sutton, Geoff, Grimes, Jonathan M, Poranen, Minna M, Bamford, Dennis H, Tuma, Roman, Stuart, David I and Mancini, Erika J (2013) Tracking in atomic detail the functional specializations in viral RecA helicases that occur during evolution. Nucleic Acids Research, 41 (20). pp. 9396-9410. ISSN 1362-4962

El Omari, Kamel, Sutton, Geoff, Ravantti, Janne J, Zhang, Hanwen, Walter, Thomas S, Grimes, Jonathan M, Bamford, Dennis H, Stuart, David I and Mancini, Erika J (2013) Plate tectonics of virus shell assembly and reorganization in phage φ8, a distant relative of mammalian reoviruses. Structure, 21 (8). pp. 1384-1395. ISSN 1878-4186

Elliott, Catherine Rebecca (2013) The over-expression, purification and crystallisation of the alternative oxidase. Doctoral thesis (PhD), University of Sussex.

F

Fentiman, Ian, Cartlidge, Christopher, Dixon, J Michael, Giamas, Georgios and Kiritsi, Marianna (2013) Journal Watch: Our panel of experts highlight the most important research articles across the spectrum of topics relevant to the field of breast cancer management. Breast Cancer Management, 2 (6). pp. 455-457. ISSN 1758-1923

Filipovic, Aleksandra, Stebbing, Justin and Giamas, Georgios (2013) Cancer stem cells - therapeutic targeting or therapy? Lancet Oncology, 14 (7). pp. 579-580. ISSN 1470-2045

G

Ghafourian, Taravat and Amin, Zeshan (2013) QSAR models for the prediction of plasma protein binding. BioImpacts, 3 (1). pp. 21-27. ISSN 2228-5652

Gray, Stephen (2013) Investigating the molecular mechanisms of meiotic recombination. Doctoral thesis (PhD), University of Sussex.

K

Kitson, Russell R A, Chang, Chuan-Hsin, Xiong, Rui, Williams, Huw E L, Davis, Adrienne L, Lewis, William, Dehn, Donna L, Siegel, David, Roe, S Mark, Prodromou, Chrisostomos, Ross, David and Moody, Christopher J (2013) Synthesis of 19-substituted geldanamycins with altered conformations and their binding to heat shock protein Hsp90. Nature Chemistry, 5 (4). pp. 307-314. ISSN 1755-4330

Krishnan, Vidisha (2013) Investigation of parasporins, the cytotoxic proteins from the bacterium Bacillus thuringiensis. Doctoral thesis (PhD), University of Sussex.

L

Lit, Lei Cheng, Scott, Susan, Zhang, Hua, Stebbing, Justin, Photiou, Andrew and Giamas, Georgios (2013) LATS2 is a modulator of estrogen receptor alpha. Anticancer Research, 33 (1). pp. 53-63. ISSN 0250-7005

M

Mather, Stuart, Scott, Simon, Temperton, Nigel, Wright, Edward, King, Barnabas and Daly, Janet (2013) Current progress with serological assays for exotic emerging/re-emerging viruses. Future Virology, 8 (8). pp. 745-755. ISSN 1746-0794

McClellan, Michael J, Wood, C David, Ojeniyi, Opeoluwa, Cooper, Tim J, Kanhere, Aditi, Arvey, Aaron, Webb, Helen M, Palermo, Richard D, Harth-Hertle, Marie L, Kempkes, Bettina, Jenner, Richard G and West, Michelle (2013) Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming. PLoS Pathogens, 9 (9). e1003636. ISSN 1553-7366

Mercer, Brenda (2013) An investigation into the function of sumoylation in genomic stability in schizosaccharomyces pombe. Doctoral thesis (PhD), University of Sussex.

Moore, Rachel, Theveneau, Eric, Pozzi, Sara, Alexandre, Paula, Richardson, Joanna, Merks, Anne, Parsons, Maddy, Kashef, Jubin, Linker, Claudia and Mayor, Roberto (2013) Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion. Development, 140. pp. 4763-4775. ISSN 0950-1991

Morgan, R G, Liddiard, K, Pearn, L, Pumford, S L, Burnett, A K, Darley, R L and Tonks, A (2013) γ-Catenin is expressed throughout normal human hematopoietic development and is required for normal PU.1-dependent monocyte differentiation. Leukemia, 27 (10). pp. 2096-2100. ISSN 1476-5551

Morgan, R G, Pearn, L, Liddiard, K, Pumford, S L, Burnett, A K, Tonks, A and Darley, R L (2013) γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin. Leukemia, 27 (2). pp. 336-43. ISSN 1476-5551

Morris, Kyle L, Chen, Lin, Raeburn, Jaclyn, Sellick, Owen R, Cotanda, Pepa, Paul, Alison, Griffiths, Peter C, King, Stephen M, O’Reilly, Rachel K, Serpell, Louise C and Adams, Dave J (2013) Chemically programmed self-sorting of gelator networks. Nature Communications, 4. p. 1480. ISSN 2041-1723

Morris, Kyle L, Zibaee, Shahin, Chen, Lin, Goedert, Michel, Sikorski, Pawel and Serpell, Louise C (2013) The structure of cross-β tapes and tubes formed by an octapeptide, αSβ1. Angewandte Chemie International Edition, 52 (8). pp. 2279-2283. ISSN 1433-7851

Métifiot, Mathieu, Maddali, Kasthuraiah, Johnson, Barry C, Hare, Stephen, Smith, Steven J, Zhao, Xue Zhi, Marchand, Christophe, Burke, Terrence R, Hughes, Stephen H, Cherepanov, Peter and Pommier, Yves (2013) Activities, crystal structures, and molecular dynamics of dihydro-1H-isoindole derivatives, inhibitors of HIV-1 integrase. ACS Chemical Biology, 8 (1). pp. 209-217. ISSN 1554-8929

N

Newby, Danielle, Freitas, Alex A and Ghafourian, Taravat (2013) Coping with unbalanced class data sets in oral absorption models. Journal of Chemical Information and Modeling, 53 (2). pp. 461-474. ISSN 1549-9596

Newby, Danielle, Freitas, Alex A and Ghafourian, Taravat (2013) Pre-processing feature selection for improved C&RT models for oral absorption. Journal of Chemical Information and Modeling, 53 (10). pp. 2730-2742. ISSN 1549-9596

P

Pellegrino, Loredana, Stebbing, Justin, Braga, Vania M, Frampton, Adam E, Jacob, Jimmy, Buluwela, Lakjaya, Jiao, Long R, Periyasamy, Manikandan, Madsen, Chris D, Caley, Matthew P, Ottaviani, Silvia, Roca-Alonso, Laura, El-Bahrawy, Mona, Coombes, R Charles, Krell, Jonathan and Castellano, Leandro (2013) miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts. Nucleic Acids Research, 41 (10). pp. 5400-5412. ISSN 1362-4962

Pinho, Filipa G, Frampton, Adam E, Nunes, Joao, Krell, Jonathan, Alshaker, Heba, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, de Giorgio, Alexander, Harding, Victoria, Waxman, Jonathan, Stebbing, Justin, Pchejetski, Dmitry and Castellano, Leandro (2013) Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation. Cancer Research, 73 (19). pp. 5936-5948. ISSN 0008-5472

Polier, Sigrun, Samant, Rahul S, Clarke, Paul A, Workman, Paul, Prodromou, Chrisostomos and Pearl, Laurence H (2013) Erratum: ATP-competitive inhibitors block protein kinase recruitment to the Hsp90-Cdc37 system (Nature Chemical Biology (2013) 9 (307-312)). Nature Chemical Biology, 9. p. 406. ISSN 1552-4450

Prodromou, Chrisostomos and Pearl, Laurence (2013) Structural basis of Hsp90 function. In: Machajewski, Timothy D, Gao, Zhenhai and Rotella, David (eds.) Inhibitors of molecular chaperones as therapeutic agents. RSC drug discovery; No. 37 . RSC Publishing, Cambridge, UK, pp. 37-64. ISBN 9781849736664

R

Raymond, Ben, Wright, Denis J, Crickmore, Neil and Bonsall, Michael B (2013) The impact of strain diversity and mixed infections on the evolution of resistance to Bacillus thuringiensis. Proceedings of the Royal Society B: Biological Sciences, 280 (1769). p. 20131497. ISSN 0962-8452

Robinson, Lucy E and Murrell-Lagnado, Ruth D (2013) The trafficking and targeting of P2X receptors. Frontiers in Cellular Neuroscience, 7. p. 233. ISSN 1662-5102

Rudd, Sean G (2013) Cellular and biochemical characterisation of PrimPol, a novel eukaryotic primase-polymerase involved in DNA damage tolerance. Doctoral thesis (PhD), University of Sussex.

Russell, Liam (2013) The conservation and landscape genetics of the sand lizard Lacerta agilis. Doctoral thesis (PhD), University of Sussex.

S

Serjeant, Anthony Frederick (2013) The ecology of great diving beetles (Dytiscus spp.) in the Somerset levels and moors. Doctoral thesis (PhD), University of Sussex.

Sharifi, Mohsen and Ghafourian, Taravat (2013) Estimation of biliary excretion of foreign compounds using properties of molecular structure. AAPS Journal, 16 (1). pp. 65-78. ISSN 1550-7416

Shiba, Tomoo, Kido, Yasutoshi, Sakamoto, Kimitoshi, Inaoka, Daniel Ken, Tsuge, Chiaki, Tatsumi, Ryoko, Balogun, Emmanuel Oluwarade, Nara, Takeshi, Aoki, Takashi, Honma, Teruki, Tanaka, Akiko, Inoue, Masayuki, Matsuoka, Shigeru, Saimoto, Hiroyuki, Moore, Anthony L., Harada, Shigeharu and Kita, Kiyoshi (2013) Structure of the trypanosome cyanide-insensitive alternative oxidase. Proceedings of the National Academy of Sciences of the United States of America, 110 (12). pp. 4580-4585. ISSN 1091-6490

Shinday, Nina M, Sawyer, Eileen K, Fischer, Bradford D, Platt, Donna M, Licata, Stephanie C, Atack, John R, Dawson, Gerard R, Reynolds, David S and Rowlett, James K (2013) Reinforcing effects of compounds lacking intrinsic efficacy at α1 subunit-containing GABAA receptor subtypes in midazolam- but not cocaine-experienced rhesus monkeys. Neuropsychopharmacology, 38 (6). pp. 1006-1014. ISSN 0893-133X

Shu, Changlong, Zhang, Jingtao, Chen, Guihua, Liang, Gemei, He, Kanglai, Crickmore, Neil, Huang, Dafang, Zhang, Jie and Song, Fuping (2013) Use of a pooled clone method to isolate a novel Bacillus thuringiensis Cry2A toxin with activity against Ostrinia furnacalis. Journal of Invertebrate Pathology, 114 (1). pp. 31-33. ISSN 0022-2011

Sinclair, Alison J (2013) Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle? Frontiers in Genetics, 4 (161). pp. 1-4. ISSN 1664-8021

Singaravelu, B, Crickmore, N, Srikanth, J, Hari, K, Sankaranarayanan, C, Nirmala, R, Radesh Krishnan, S and Meghna, M (2013) Prospecting for scarabid specific Bacillus thuringiensis crystal toxin cry8 gene in sugarcane ecosystem of Tamil Nadu, India. Journal of Sugarcane Research, 3 (2). pp. 141-144. ISSN 2249-927X

Skalska, Lenka, White, Robert E, Parker, Gillian A, Turro, Ernest, Sinclair, Alison J, Pachos, Kostas and Allday, Martin J (2013) Induction of p16INK4a is the major barrier to proliferation when Epstein-Barr virus (EBV) transforms primary B cells into Lymphoblastoid cell lines. PLoS Pathogens, 9 (2). e1003187. ISSN 1553-7366

Smalley, Sarah (2013) Investigating the use of connectivity mapping to manipulate MGMT protein levels in T98G glioblastoma multiforme cells. Doctoral thesis (PhD), University of Sussex.

Smith, J R, de Billy, E, Hobbs, S, Powers, M, Prodromou, C, Pearl, L, Clarke, P A and Workman, P (2013) Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins. Oncogene, 34 (1). pp. 15-26. ISSN 0950-9232

Smith, S E, Gibson, M S, Wash, R S, Ferrara, F, Wright, Edward, Temperton, N, Kellam, P and Fife, M (2013) Chicken interferon-inducible transmembrane protein 3 restricts influenza viruses and lyssaviruses in vitro. Journal of Virology, 87 (23). pp. 12957-12966. ISSN 0022-538X

Stebbing, J, Filipovic, A, Lit, L C, Blighe, K, Grothey, A, Xu, Y, Miki, Y, Chow, L W, Coombes, R C, Sasano, H, Shaw, J A and Giamas, G (2013) LMTK3 is implicated in endocrine resistance via multiple signaling pathways. Oncogene, 32 (28). pp. 3371-3380. ISSN 0950-9232

Stebbing, J, Filipović, A and Giamas, G (2013) Claudin-1 as a promoter of EMT in hepatocellular carcinoma. Oncogene, 32 (41). pp. 4871-4872. ISSN 0950-9232

T

Tabib-Salazar, Aline, Liu, Bing, Doughty, Philip, Lewis, Richard A, Ghosh, Somadri, Parsy, Marie-Laure, Simpson, Peter J, O'Dwyer, Kathleen, Matthews, Steve J and Paget, Mark S (2013) The actinobacterial transcription factor RbpA binds to the principal sigma subunit of RNA polymerase. Nucleic Acids Research, 41 (11). pp. 5679-5691. ISSN 0305-1048

Tsoureas, Nikolaos, Summerscales, Owen T, Cloke, F Geoffrey N and Roe, S Mark (2013) Steric effects in the reductive coupling of CO by mixed-sandwich uranium(III) complexes. Organometallics, 32 (5). pp. 1353-1362. ISSN 0276-7333

W

Wakatsuki, Takeru, LaBonte, Melissa J, Bohanes, Pierre O, Zhang, Wu, Yang, Dongyun, Azuma, Mizutomo, Barzi, Afsaneh, Ning, Yan, Loupakis, Fotios, Saadat, Siamak, Volz, Nico, Stintzing, Sebastian, El-Khoueiry, Rita, Koizumi, Wasaburo, Watanabe, Masahiko, Shah, Manish, Stebbing, Justin, Giamas, Georgios and Lenz, Heinz-Josef (2013) Prognostic role of lemur tyrosine kinase-3 germline polymorphisms in adjuvant gastric cancer in Japan and the United States. Molecular Cancer Therapeutics, 12 (10). pp. 2261-2272. ISSN 1535-7163

Willett, Mark, Brocard, Michele, Pollard, Hilary J and Morley, Simon J (2013) mRNA encoding WAVE-Arp2/3-associated proteins is co-localized with foci of active protein synthesis at the leading edge of MRC5 fibroblasts during cell migration. The Biochemical Journal, 452 (1). pp. 45-55. ISSN 1470-8728

Z

Zhang, H, Xu, Y, Filipovic, A, Lit, L C, Koo, C-Y, Stebbing, J and Giamas, G (2013) SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1. British Journal of Cancer, 109 (10). pp. 2675-2684. ISSN 1532-1827

Zhang, Hua, Koo, Chuay Yeng, Stebbing, Justin and Giamas, Georgios (2013) The dual function of KSR1: a pseudokinase and beyond. Biochemical Society Transactions, 41 (4). pp. 1078-82. ISSN 0300-5127

Zimmerman, Kristin Mara (2013) The cellular impact of diminished DNA origin licensing capacity and its potential therapeutic exploitation. Doctoral thesis (PhD), University of Sussex.