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Antonio, L S, Stewart, A P, Xu, X J, Varanda, W A, Murrell-Lagnado, R D and Edwardson, J M (2011) P2X4 receptors interact with both P2X2 and P2X7 receptors in the form of homotrimers. British Journal of Pharmacology, 163 (5). pp. 1069-1077. ISSN 0007-1188

Cherepanov, Peter, Maertens, Geodele N and Hare, Stephen (2011) Structural insights into the retroviral DNA integration apparatus. Current Opinion in Structural Biology, 21 (2). pp. 249-256. ISSN 0959-440X

Crickmore, Neil, Badenes-Pérez, Francisco, Baxter, Simon, Heckel, David, Jiggins, Chris, Kain, Wendy, Morrison, Anna, Vogel, Heiko and Wang, Ping (2011) Parallel evolution of Bt toxin resistance in Lepidoptera. Genetics, 189 (2). pp. 675-679. ISSN 0016-6731

El Omari, Kamel, Hoosdally, Sarah J, Tuladhar, Kapil, Karia, Dimple, Vyas, Paresh, Patient, Roger, Porcher, Catherine and Mancini, Erika J (2011) Structure of the leukemia oncogene LMO2: implications for the assembly of a hematopoietic transcription factor complex. Blood, 117 (7). pp. 2146-2156. ISSN 1528-0020

Filipović, A, Giamas, G and Stebbing, J (2011) The potential role of cyclooxygenase-2 (COX-2) during early breast cancer therapy. Annals of Oncology, 22 (8). pp. 1700-1702. ISSN 0923-7534

Flower, Kirsty, Thomas, David, Heather, James, Ramasubramanyan, Sharada, Jones, Susan and Sinclair, Alison J. (2011) Epigenetic Control of Viral Life-Cycle by a DNA-Methylation Dependent Transcription Factor. PLoS ONE, 6 (10). e25922. ISSN 1932-6203

Giamas, G (2011) LMTK3: a novel therapeutic target for breast cancer. Pharmacogenomics, 12 (7). pp. 931-932. ISSN 1462-2416

Giamas, Georgios, Filipović, Aleksandra, Jacob, Jimmy, Messier, Walter, Zhang, Hua, Yang, Dongyun, Zhang, Wu, Shifa, Belul Assefa, Photiou, Andrew, Tralau-Stewart, Cathy, Castellano, Leandro, Green, Andrew R, Coombes, R Charles, Ellis, Ian O, Ali, Simak, Lenz, Heinz-Josef and Stebbing, Justin (2011) Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nature Medicine, 17 (6). pp. 715-719. ISSN 1546-170X

Hare, Stephen, Smith, Steven J, Métifiot, Mathieu, Jaxa-Chamiec, Albert, Pommier, Yves, Hughes, Stephen H and Cherepanov, Peter (2011) Structural and functional analyses of the second-generation integrase strand transfer inhibitor dolutegravir (S/GSK1349572). Molecular Pharmacology, 80 (4). pp. 565-572. ISSN 0026-895X

Marshall, Karen, Morris, Kyle L, Charlton, Deborah, O’Reilly, Nicola, Lewis, Laurence, Walden, Helen and Serpell, Louise C (2011) Hydrophobic, aromatic and electrostatic interactions play a central role in amyloid fibril formation. Biochemistry, 50 (12). pp. 2061-2071. ISSN 0006-2960

McGonnell, Imelda M, Graham, Anthony, Richardson, Joanna, Fish, Jennifer L, Depew, Michael J, Dee, Chris T, Holland, Peter WH and Takahashi, Tokiharu (2011) Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene. Evolution and Development, 13 (4). pp. 343-351. ISSN 1520-541X

Millson, Stefan H, Chua, Chun-Song, Roe, S Mark, Polier, Sigrun, Solovieva, Svetlana, Pearl, Laurence H, Sim, Tiow-Suan, Prodromou, Chrisostomos and Piper, Peter W (2011) Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90. FASEB Journal, 25 (11). pp. 3828-3837. ISSN 0892-6638

Mollapour, Mehdi, Tsutsumi, Shinji, Truman, Andrew W, Xu, Wanping, Vaughan, Cara K, Beebe, Kristin, Konstantinova, Anna, Vourganti, Srinivas, Panaretou, Barry, Piper, Peter W, Trepel, Jane B, Prodromou, Chrisostomos, Pearl, Laurence H and Neckers, Len (2011) Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Molecular Cell, 41 (6). pp. 672-681. ISSN 1097-2765

Moore, A, Affourtit, C and Carré, J (2011) Interaction of purified plant alternative oxidase from Arum maculatum with pyruvate. FEBS Letters, 585 (2). pp. 397-401. ISSN 0014-5793

Morley, Simon, Brocard, Michele, Davide, Alexandre and Willett, Mark (2011) Translation initiation factors and active sites of protein synthesis co-localise at the leading edge of migrating MRC5 fibroblasts. Biochemical Journal, 438 (1). pp. 217-227. ISSN 0264-6021

Page, Tristan, Gitcho, Michael A, Mosaheb, Sabrina, Carter, Deborah, Chakraverty, Sumi, Perry, Robert H, Bigio, Eileen H, Gearing, Marla, Ferrer, Isidre, Goate, Alison M, Cairns, Nigel J and Thorpe, Julian R (2011) FUS immunogold labelling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS proteinopathy. Journal of Molecular Neuroscience, 45 (3). pp. 409-421. ISSN 0895-8696

Palermo, Richard D, Webb, Helen M and West, Michelle J (2011) RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus. PLoS Pathogens, 7 (10). e1002334. ISSN 1553-7374

Schlick, Sandra N, Wood, C David, Gunnell, Andrea, Webb, Helen M, Khasnis, Sarika, Schepers, Aloys and West, Michelle J (2011) Upregulation of the cell-cycle regulator RGC-32 in Epstein-Barr virus-immortalized cells. PLoS ONE, 6 (12). e28638. ISSN 1932-6203

Serpell, Louise, Adams, Dave, Chen, Lin, Lotze, Gudrun, Morris, Kyle, Pont, Guillaume and Squires, Adam (2011) Salt-induced hydrogelation of functionalised-dipeptides at high pH. Chemical Communications, 47. 12071 - 12073. ISSN 1359-7345

Stebbing, Justin, Filipović, Aleksandra and Giamas, Georgios (2011) [Editorial] LMTK3 and evolution. Oncotarget, 2. pp. 428-429. ISSN 1949-2553

Stebbing, Justin, Filipović, Aleksandra and Giamas, Georgios (2011) Lemur tyrosine kinase-3 (LMTK3) in cancer and evolution. Oncotarget, 2 (6). pp. 428-9. ISSN 1949-2553

Vosler, Peter S, Gao, Yanqin, Brennan, Christopher S, Yanagiya, Akiko, Gan, Yu, Cao, Guodong, Zhang, Feng, Morley, Simon J, Sonenberg, Nahum, Bennett, Michael V L and Chen, Jun (2011) Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death. Proceedings of the National Academy of Sciences, 108 (44). pp. 18102-18107. ISSN 1091-6490

Willett, Mark, Brocard, Michele, Davide, Alexandre and Morley, Simon J (2011) Translation initiation factors and active sites of protein synthesis co-localize at the leading edge of migrating fibroblasts. The Biochemical Journal, 438 (1). pp. 217-227. ISSN 1470-8728

Williams, Thomas L, Johnson, Benjamin R G, Urbanc, Brigita, Jenkins, A Toby A, Connell, Simon D A and Serpell, Louise C (2011) Alzheimer's Aß42 oligomers but not fibrils simultaneously bind to and cause damage to ganglioside containing lipid membranes. Biochemical Journal, 439. pp. 67-77.

Book Section

Hare, S, Cherepanov, P and Engelman, A (2011) Structural aspects of Lentiviral Integrase-LEDGF interaction. In: Neamati, Nouri and Wang, Binghe (eds.) HIV-1 Integrase: Mechanism and Inhibitor Design. Wiley, pp. 131-140. ISBN 9780470184745

Conference Proceedings

Winder, T, Giamas, G, Zhang, W, Yang, D, Bohanes, P O, Ning, Y, Gerger, A, Labonte, M J, Stebbing, J and Lenz, H (2011) Use of insulin-like growth factor (IGF) pathway polymorphism IGF1R_rs2016347 to predict tumor recurrence in estrogen receptor-positive breast cancer patients. 2011 ASCO Annual Meeting I, Chicago, Illinois, June 03 - June 07, 2011. Published in: Journal of Clinical Oncology. 29 (15) 538-538. American Society of Clinical Oncology ISSN 0732-183X

Thesis

Al-Fartusie, Falah Sumoon Daghal (2011) Engineering and characterisation of novel protein covalent linkages in horseradish peroxidase (HRP): effect on structure and function. Doctoral thesis (DPhil), University of Sussex.

Braithwaite, Natalie Emma (2011) Functional genomics and signalling in invasive growth of Schizosaccharomyces pombe. Doctoral thesis (DPhil), University of Sussex.

Brunton, Holly (2011) Investigating the role of higher order chromatin structure and DNA damage complexity on ATM signalling and G2/M checkpoint arrest. Doctoral thesis (DPhil), University of Sussex.

Chambers, Helen (2011) Investigating the effects of repair of DNA single-strand breaks on chromatin structure. Doctoral thesis (DPhil), University of Sussex.

Cloney, Ross (2011) Involvement of human DNA polymerase kappa in nucleotide excision repair. Doctoral thesis (DPhil), University of Sussex.

Damerell, David Robert (2011) The computational analysis of post-translational modifications. Doctoral thesis (DPhil), University of Sussex.

Fallas, Andrea Jennifer (2011) C1, SAP and ZiCo: structural studies of three metal‑binding proteins from a crystallographic perspective. Doctoral thesis (DPhil), University of Sussex.

Flower, Kirsty (2011) Methylation dependent interactions of viral transcription factor Zta with DNA. Doctoral thesis (DPhil), University of Sussex.

Fontebasso, Yari (2011) Novel insights into the DNA interstrand cross-link repair in Schizosaccharomyces pombe: characterisation of Fan1 through standard and high-throughput genetic analysis. Doctoral thesis (DPhil), University of Sussex.

Gamper, Frederick (2011) Dysregulated toll-like receptor mechanisms: the cause of atherosclerosis? Doctoral thesis (DPhil), University of Sussex.

George, Zenas Okon (2011) Expression and genetic manipulation of Bacillus thuringiensis toxins for improved toxicity and development of a protocol for in vivo selection of toxin variants with improved activity. Doctoral thesis (DPhil), University of Sussex.

Lin, Su-Jiun (2011) Structure/function analysis of the essential protein Rad4TopBP1 in S. pombe. Doctoral thesis (DPhil), University of Sussex.

Mishra, Ruchir (2011) Characterisation of insecticide resistance in Plutella xylostella (the diamondback moth). Doctoral thesis (DPhil), University of Sussex.

Pannell, Sarah Esme (2011) Structural determinants of peroxidase activities. Doctoral thesis (DPhil), University of Sussex.

Philpott, Amelia (2011) Investigations into the biochemical and cellular biology of a cytoplasmic dynein mutation, abnormal rear leg (Arl). Doctoral thesis (DPhil), University of Sussex.

Roeseler de Rivera, Francois-Xavier P.G. (2011) The effects of LPS plus pro-inflammatory cytokines on glycogen synthesis in C2C12 myocytes. Doctoral thesis (DPhil), University of Sussex.

Strain-Damerell, Claire Michelle (2011) Functional analysis of Rex, a sensor of the NADH/NAD+ redox poise in Streptomyces coelicolor. Doctoral thesis (DPhil), University of Sussex.

Warren, Ben (2011) Hearing and acoustic interaction in mosquitoes. Doctoral thesis (PhD), University of Sussex.