A

Abraham, Michael H, Hassanisadi, Mostafa, Jalali-Heravi, Mehdi, Ghafourian, Taravat, Cain, William S and Cometto-Muñiz, J Enrique (2003) Draize rabbit eye test compatibility with eye irritation thresholds in humans: a quantitative structure-activity relationship analysis. Toxicological Sciences, 76 (2). pp. 384-391. ISSN 1096-6080

Aherne, Wynne, Maloney, Alison, Prodromou, Chrisostomos, Rowlands, Martin G, Hardcastle, Anthea, Boxall, Katherine, Clarke, Paul, Walton, Michael I, Pearl, Laurence and Workman, Paul (2003) Assays for HSP90 and inhibitors. Methods in Molecular Medicine, 85. pp. 149-161. ISSN 1543-1894

Amoah-Buahin, Evelyn, Ramdath, Ramona, Antoniadi, Thalia, Bone, Neil and Armstrong, John (2003) Schizosaccharomyces pombe: a dimorphic fission yeast. In: 21st International Conference on Yeast Genetics and Molecular Biology, JUL 07-12, 2003, GOTHENBURG, SWEDEN.

B

Berriman, John, Serpell, Louise C, Oberg, Keith A, Fink, Anthony L, Goedert, Michel and Crowther, R Anthony (2003) Tau filaments from human brain and from in vitro assembly of recombinant protein show cross-ß structure. Proceedings of the National Academy of Sciences, 100 (15). pp. 9034-9038. ISSN 0027-8424

Bone, N, Nurse, P and Armstrong, J (2003) VTC4: a regulator of vacuole size in fission yeast. In: 21st International Conference on Yeast Genetics and Molecular Biology, JUL 07-12, 2003, Gothenburg, Sweden.

Brekasis, Dimitris and Paget, Mark S B (2003) A novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3(2). EMBO Journal, 22 (18). pp. 4856-4865. ISSN 0261-4189

Brown, J, Walter, T S, Carter, L, Abrescia, N G A, Aricescu, A R, Batuwangala, T D, Bird, L E, Brown, N, Chamberlain, P P, Davis, S J, Dubinina, E, Endicott, J, Fennelly, J A, Gilbert, R J C, Harkiolaki, M, Hon, W-C, Kimberley, F, Love, C A, Mancini, E J, Manso-Sancho, R, Nichols, C E, Robinson, R A, Sutton, G C, Schueller, N, Sleeman, M C, Stewart-Jones, G B, Vuong, M, Welburn, J, Zhang, Z, Stammers, D K, Owens, R J, Jones, E Y, Harlos, K and Stuart, D I (2003) A procedure for setting up high-throughput nanolitre crystallization experiments. II. Crystallization results. Journal of Applied Crystallography, 36 (2). pp. 315-318. ISSN 0021-8898

Butler, Miranda J, Jacobsen, Thomas L, Cain, Donna M, Jarman, Michael G, Hubank, Michael, Whittle, J Robert S, Phillips, Roger and Simcox, Amanda (2003) Discovery of genes with highly restricted expression patterns in the Drosophila wing disc using DNA oligonucleotide microarrays. Development, 130. pp. 659-670. ISSN 0950-1991

C

Crowther, Damian C, Serpell, Louise C, Daffron, Timothy R, Gooptu, Bibek and Lomas, David A (2003) Nucleation of alpha1-Antichymotrypsin Polymerization. Biochemistry, 42 (8). pp. 2355-2363. ISSN 0006-2960

D

d'Adda di Fagagna, Fabrizio, Weller, Geoffrey R, Doherty, Aidan and Jackson, Stephen P (2003) The Gam protein of bacteriophage Mu is an orthologue of eukaryotic Ku. EMBO Reports, 4 (1). pp. 47-52. ISSN 1469-221X

de Maagd, Ruud A, Bravo, Alejandra, Berry, Colin, Crickmore, Neil and Schnepf, H Ernest (2003) Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria. Annual Review of Genetics, 37. pp. 409-433. ISSN 0066-4197

H

Harris, Sheila, Kemplen, Caroline, Caspari, Thomas, Chan, Christopher, Lindsay, Howard D, Poitelea, Marius, Carr, Antony M and Price, Clive (2003) Delineating the position of rad4+/cut5+ within the DNA-structure checkpoint pathways in Schizosaccharomyces pombe. Journal of Cell Science, 116 (17). pp. 3519-3529. ISSN 0021-9533

Hashemzadeh-Bonehi, Lida, Curtis, Penelope S, Morley, Simon J, Thorpe, Julian R and Pain, Virginia M (2003) Overproduction of a conserved domain of fission yeast and mammalian translation initiation factor eIF4G causes aberrant cell morphology and results in disruption of the localization of F-actin and the organization of microtubules. Genes to Cells, 8 (2). pp. 163-178. ISSN 1356-9597

Hedgecoe, Adam and Martin, Paul (2003) The Drugs Don't Work: Expectations and the Shaping of Pharmacogenetics. Social Studies of Science, 33 (3). pp. 327-364. ISSN 1460-3659

Hicks, Matthew R., Al-Mehairi, Salama S. and Sinclair, Alison J. (2003) The Zipper Region of Epstein-Barr Virus bZIP Transcription Factor Zta Is Necessary but Not Sufficient To Direct DNA Binding. Journal of Virology, 77 (14). pp. 8173-8177. ISSN 0022-538X

J

Jenkinson, Elizabeth and Crickmore, Neil (2003) Identification of a novel DNA methyltransferase activity from Bacillus thuringiensis. Current Microbiology, 47 (2). pp. 144-145. ISSN 0343-8651

Jones, Rhiannon E, Chapman, J Ross, Puligilla, Chandrakala, Murray, Johanne M, Carr, Antony M, Ford, Christopher C and Lindsay, Howard D (2003) XRad17 Is Required for the Activation of XChk1 But Not XCds1 during Checkpoint Signaling in Xenopus. Molecular Biology of the Cell, 14 (9). pp. 3898-3910. ISSN 1059-1524

Jones, Susan, Barker, Jonathan A, Nobeli, Irene and Thornton, Janet M (2003) Using structural motifs to identify proteins with DNA binding function. Nucleic Acids Research, 31 (11). pp. 2811-2823. ISSN 0305-1048

Jones, Susan, Shanahan, Hugh P, Berman, Helen M and Thornton, Janet M (2003) Using electrostatic potentials to predict DNA-binding sites on DNA-binding proteins. Nucleic Acids Research, 31 (24). pp. 7189-7198. ISSN 0305-1048

L

Li, Wei, Bottrill, Andrew R, Bibb, Maureen J, Buttner, Mark J, Paget, Mark S B and Kleanthous, Colin (2003) The Role of Zinc in the Disulfide Stress-Regulated Anti-Sigma Factor RsrA from Streptomyces coelicolor. Journal of Molecular Biology, 333 (2). pp. 461-472. ISSN 0022-2836

Lynch, Anthony, Harvey, James, Aylott, Michael, Nicholas, Emma, Burman, Mark, Siddiqui, Ayesha, Walker, Sarah and Rees, Robert (2003) Investigations into the concept of a threshold for topoisomerase inhibitor-induced clastogenicity. Mutagenesis, 18 (4). pp. 345-53. ISSN 0267-8357

M

Mancini, E J, Grimes, J M, Malby, R, Sutton, G C, Kainov, D E, Juuti, J T, Makeyev, E V, Tuma, R, Bamford, D H and Stuart, D I (2003) Order and disorder in crystals of hexameric NTPases from dsRNA bacteriophages. Acta Crystallographica Section D: Biological Crystallography, 59 (12). pp. 2337-2341. ISSN 0907-4449

Meyer, Philipe, Prodromou, Chrisostomos, Hu, Bin, Vaughan, Cara, Roe, S Mark, Panaretou, Barry, Piper, Peter W and Pearl, Laurence H (2003) Structural and functional analysis of the middle segment of hsp90: implications for ATP hydrolysis and client protein and cochaperone interactions. Molecular Cell, 11 (3). pp. 647-658. ISSN 1097-2765

Morley, Simon J and Naegele, Susanne (2003) Phosphorylation of initiation factor 4E is resistant to SB203580 in cells expressing a drug-resistant mutant of stress-activated protein kinase 2a/p38. Cellular Signalling, 15 (8). pp. 741-749. ISSN 0898-6568

N

Nokhodchi, A, Shokri, J, Dashbolaghi, A, Hassan-Zadeh, D, Ghafourian, T and Barzegar-Jalali, M (2003) The enhancement effect of surfactants on the penetration of lorazepam through rat skin. International Journal of Pharmaceutics, 250 (2). pp. 359-369. ISSN 0378-5173

P

Paget, Mark and Helmann, John (2003) Protein family review - The sigma(70) family of sigma factors. Genome Biology, 4 (1). ISSN 1465-6906

Paget, Mark S B and Buttner, Mark J (2003) Thiol-based regulatory switches. Annual Review Genetics, 37. pp. 91-121. ISSN 0066-4197

Paget, Mark S B and Helmann, John D (2003) The Sig70 family of sigma factors. Genome Biology, 4 (1). ISSN 1465-6906

Piper, Peter W, Millson, Stefan H, Mollapour, Mehdi, Panaretou, Barry, Siligardi, Giuliano, Pearl, Laurence H and Prodromou, Chrisostomos (2003) Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast. European Journal of Biochemistry, 270 (23). pp. 4689-4695. ISSN 0014-2956

Piper, Peter W, Panaretou, Barry, Millson, Stefan H, Truman, Andrew, Mollapour, Mehdi, Pearl, Laurence and Prodromou, Chrisostomos (2003) Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors. Gene, 302 (1-2). pp. 165-170. ISSN 0378-1119

Prodromou, Chrisostomos and Pearl, Laurence H (2003) Structure and functional relationships of Hsp90. Current Cancer Drug Targets, 3 (5). pp. 301-323. ISSN 1568-0096

R

Reynolds, Lindsey, Ullman, Christopher, Moore, Michael, Isalan, Mark, West, Michelle J, Clapham, Paul, Klug, Aaron and Choo, Yen (2003) Repression of the HIV-1 5' LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors. Proceedings of the National Academy of Sciences, 100 (4). pp. 1615-1620. ISSN 0027-8424

Royle, Stephen J and Murrell-Lagnado, Ruth D (2003) Constitutive cycling: a general mechanism to regulate cell surface proteins. BioEssays, 25 (1). pp. 39-46. ISSN 0265-9247

S

Sikorski, Pawel, Atkins, Edward D T and Serpell, Louise C (2003) Structure and textures of fibrous crystals of the Abeta (11-25) peptide fragment from Alzheimer's Abeta Amyloid protein. Structure, 11 (1). pp. 1-2. ISSN 0969-2126

Sinclair, Alison J. (2003) bZIP proteins of human gammaherpesviruses. Journal of General Virology, 84 (8). pp. 1941-1949. ISSN 0022-1317

Smith, David P, Jones, Susan, Serpell, Louise C, Sunde, Margaret and Radford, Sheena E (2003) A Systematic Investigation into the Effect of Protein Destabilisation on Beta 2-Microglobulin Amyloid Formation. Journal of Molecular Biology, 330 (5). pp. 943-954. ISSN 0022-2836

Spriggs, Ruth V, Artymiuk, Peter J and Willett, Peter (2003) Searching for patterns of amino acids in 3D protein structures. Journal of Chemical Information and Computer Sciences, 43 (2). pp. 412-421. ISSN 0095-2338

T

Taylor, D L, Ward, P N, Leigh, J A and Bowler, L D (2003) Identification of a Differentially Expressed Oligopeptide Binding Protein (OppA2) in Streptococcus uberis by Representational Difference Analysis of cDNA. Journal of Bacteriology, 185 (17). pp. 5210-9. ISSN 0021-9193

U

Ueno, Masaru, Nakazaki, Tomofumi, Akamatsu, Yufuko, Watanabe, Kikuo, Tomita, Kazunori, Lindsay, Howard D, Shinagawa, Hideo and Iwasaki, Hiroshi (2003) Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance. Molecular and Cellular Biology, 23 (18). pp. 6553-6563. ISSN 0270-7306

W

Walsh, Derek, Meleady, Paula, Power, Brendan, Morley, Simon J and Clynes, Martin (2003) Increased levels of the translation initiation factor eIF4E in differentiating epithelial lung tumor cell lines. Differentiation, 71 (2). pp. 126-134. ISSN 0301-4681