Items for Atack, John

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Number of items: 11.

Article

Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W and Oliver, Antony W (2016) Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal, 473 (13). pp. 1869-1879. ISSN 0264-6021

Walker, Sarah, Meisenberg, Cornelia, Bibby, Rachel A, Askwith, Trevor, Williams, Gareth, Rininsland, Frauke H, Pearl, Laurence H, Oliver, Antony W, El-Khamisy, Sherif, Ward, Simon and Atack, John R (2014) Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. Analytical Biochemistry, 454. pp. 17-22. ISSN 0003-2697

Shinday, Nina M, Sawyer, Eileen K, Fischer, Bradford D, Platt, Donna M, Licata, Stephanie C, Atack, John R, Dawson, Gerard R, Reynolds, David S and Rowlett, James K (2013) Reinforcing effects of compounds lacking intrinsic efficacy at α1 subunit-containing GABAA receptor subtypes in midazolam- but not cocaine-experienced rhesus monkeys. Neuropsychopharmacology, 38 (6). pp. 1006-1014. ISSN 0893-133X

Eng, W, Atack, J, Bergstrom, M, Sanabria, S, Appel, L, Dawson, G R, Sciberras, G, Hargreaves, R J, Langstrom, B and Burns, H D (2010) Occupancy of human brain GABA A receptors by the novel α5 subtype-selective benzodiazepine site inverse agonist α5IA as measured using [ 11C]flumazenil PET imaging. Neuropharmacology, 59 (7). pp. 635-639. ISSN 0028-3908

Dixon, Claire I, Morris, Hannah V, Breen, Gerome, Desrivieres, Sylvane, Jugurnauth, Sarah, Steiner, Rebecca C, Vallada, Homero, Guindalini, Camila, Laranjeira, Ronaldo, Messas, Guilherme, Rosahl, Thomas W, Atack, John R, Peden, Dianne R, Belelli, Delia, Lambert, Jeremy J, King, Sarah L, Schumann, Gunter and Stephens, David N (2010) Cocaine effects on mouse incentive-learning and human addiction are linked to α2 subunit-containing GABAA receptors. Proceedings of the National Academy of Sciences, 107 (5). pp. 2289-2294. ISSN 0027-8424

Atack, John R, Wong, Dean F, Fryer, Tim D, Ryan, Christine, Sanabria, Sandra, Zhou, Yun, Dannals, Robert F, Eng, Wai-si, Gibson, Raymond E, Burns, H Donald, Vega, Jose M, Vessy, Laura, Scott-Stevens, Paul, Beech, John S, Baron, Jean-Claude, Sohal, Bindi, Schrag, Michael L, Aigbirhio, Franklin I, McKernan, Ruth M and Hargreaves, Richard J (2010) Benzodiazepine binding site occupancy by the novel GABAA receptor subtype-selective drug 7-(1,1-dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine (TPA023) in rats, primates, and humans. The Journal of Pharmacology and Experimental Therapeutics, 332 (1). pp. 17-25. ISSN 0022-3565

Atack, John R (2010) Preclinical and clinical pharmacology of the GABAA receptor α5 subtype-selective inverse agonist α5IA. Pharmacology & Therapeutics, 125 (1). pp. 11-26. ISSN 0163-7258

Atack, John R, Maubach, Karen A, Wafford, Keith A, O'Connor, Desmond, Rodrigues, A David, Evans, David C, Tattersall, F David, Chambers, Mark S, MacLeod, Angus M, Eng, Wai-Si, Ryan, Christine, Hostetler, Eric, Sanabria, Sandra M, Gibson, Raymond E, Krause, Stephen, Burns, H Donald, Hargreaves, Richard J, Agrawal, Nancy G B, McKernan, Ruth M, Murphy, M Gail, Gingrich, Kevin, Dawson, Gerard R, Musson, Donald G and Petty, Kevin J (2009) In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist. Journal of Pharmacology and Experimental Therapeutics, 331 (2). pp. 470-484. ISSN 0022-3565

Atack, John R, Eng, Wai-Si, Gibson, Ray E, Ryan, Christine, Francis, Barbara, Sohal, Bindi, Dawson, Gerard R, Hargreaves, Richard J and Burns, H Donald (2009) The plasma-occupancy relationship of the novel GABAA receptor benzodiazepine site ligand, alpha5IA, is similar in rats and primates. British Journal of Pharmacology, 157 (5). pp. 796-803. ISSN 1476-5381

Van Laere, Koen, Bormans, Guy, Sanabria-Bohórquez, Sandra M, de Groot, Tjibbe, Dupont, Patrick, De Lepeleire, Inge, de Hoon, Jan, Mortelmans, Luc, Hargreaves, Richard J, Atack, John R and Burns, H Donald (2008) In vivo characterization and dynamic receptor occupancy imaging of TPA023B, an alpha 2/alpha 3/alpha 5 subtype selective gamma-aminobutyric acid-a partial agonist. Biological Psychiatry, 64 (2). pp. 153-161. ISSN 0006-3223

Stephens, David N, Pistovkacova, Jana, Worthing, Lynn, Atack, John R and Dawson, Gerard R (2005) Role of GABAA α5-containing receptors in ethanol reward in the mouse: the effects of targeted gene deletion and a selective inverse agonist. European Journal of Pharmacology, 526 (1-3). pp. 240-250. ISSN 0014-2999

This list was generated on Mon Jun 26 20:02:09 2017 BST.