Items for Doherty, Aidan

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Article

Plocinski, Przemyslaw, Brissett, Nigel C, Bianchi, Julie, Brzostek, Anna, Korycka-Machała, Małgorzata, Dziembowski, Andrzej, Dziadek, Jaroslaw and Doherty, Aidan J (2017) DNA Ligase C and Prim-PolC participate in base excision repair in mycobacteria. Nature Communications. ISSN 2041-1723

Guilliam, Thomas A, Brissett, Nigel C, Ehlinger, Aaron, Keen, Benjamin A, Kolesar, Peter, Taylor, Elaine, Bailey, Laura J, Lindsay, Howard, Chazin, Walter J and Doherty, Aidan J (2017) Molecular basis for PrimPol recruitment to replication forks by RPA. Nature Communications, 8. a15222. ISSN 2041-1723

Castañeda-García, A, Prieto, A I, Rodríguez-Beltrán, J, Alonso, N, Cantillon, D, Costas, C, Pérez-Lago, L, Zegeye, E D, Herranz, M, Plociński, P, Tonjum, T, García de Viedma, D, Paget, M, Waddell, S J, Rojas, A M, Doherty, A J and Blázquez, J (2017) A non-canonical mismatch repair pathway in prokaryotes. Nature Communications, 8. a14246. ISSN 2041-1723

Kobayashi, Kaori, Guilliam, Thomas A, Tsuda, Masataka, Yamamoto, Junpei, Bailey, Laura J, Iwai, Shigenori, Takeda, Shunichi, Doherty, Aidan J and Hirota, Kouji (2016) Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides. Cell Cycle, 15 (15). pp. 1997-2008. ISSN 1538-4101

Guilliam, Thomas A, Bailey, Laura J, Brissett, Nigel C and Doherty, Aidan J (2016) PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities. Nucleic Acids Research, 44 (7). pp. 3317-3329. ISSN 0305-1048

Schiavone, Davide, Jozwiakowski, Stanislaw K, Romanello, Marina, Guilbaud, Guillaume, Guilliam, Thomas A, Bailey, Laura J, Sale, Julian E and Doherty, Aidan J (2016) PrimPol is required for replicative tolerance of G quadruplexes in vertebrate cells. Molecular Cell, 61 (1). pp. 161-169. ISSN 1097-2765

Bailey, Laura J, Bianchi, Julie, Hegarat, Nadia, Hochegger, Helfrid and Doherty, Aidan J (2015) PrimPol-deficient cells exhibit a pronounced G2 checkpoint response following UV damage. Cell Cycle, 15 (7). pp. 908-918. ISSN 1538-4101

Jozwiakowski, Stanislaw K, Borazjani Gholami, Farimah and Doherty, Aidan J (2015) Archaeal replicative primases can perform translesion DNA synthesis. Proceedings of the National Academy of Sciences, 112 (7). E633-E638. ISSN 0027-8424

Guilliam, Thomas A, Jozwiakowski, Stanislaw K, Ehlinger, Aaron, Barnes, Ryan P, Rudd, Sean G, Bailey, Laura J, Skehel, J Mark, Eckert, Kristin A, Chazin, Walter J and Doherty, Aidan J (2015) Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins. Nucleic Acids Research, 43 (2). pp. 1056-1068. ISSN 0305-1048

Bartlett, Edward J, Brissett, Nigel C, Plocinski, Przemyslaw, Carlberg, Tom and Doherty, Aidan J (2015) Molecular basis for DNA strand displacement by NHEJ repair polymerases. Nucleic Acids Research. gkv965. ISSN 0305-1048

Guilliam, Thomas A, Keen, Benjamin A, Brissett, Nigel C and Doherty, Aidan J (2015) Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes. Nucleic Acids Research, 43 (14). pp. 6651-6664. ISSN 0305-1048

Hentges, Pierre, Waller, Helen Rachel, Reis, Clara C, Ferreira, Miguel Godinho and Doherty, Aidan J (2014) Cdk1 restrains NHEJ through phosphorylation of XRCC4-like factor Xlf1. Cell Reports, 9 (6). pp. 2011-2017. ISSN 2211-1247

Jozwiakowski, Stanislaw A, Keith, Brian J, Gilroy, Louise, Doherty, Aidan J and Connolly, Bernard A (2014) An archaeal family-B DNA polymerase variant able to replicate past DNA damage: occurrence of replicative and translesion synthesis polymerases within the B family. Nucleic Acids Research, 42 (15). pp. 9949-9963. ISSN 0305-1048

Rasheduzzaman, Chowdhury, Brissett, Nigel, Krojer, Tobias, Ho, Chia-hua, Ng, Stanley S, Clifton, Ian J, Ge, Wei, Kershaw, Nadia J, Fox, Gavin C, Muniz, Joao R C, Vollmar, Melanie, Phillips, Claire, Pilka, Ewa S, Kavanagh, Kathryn L, von Delft, Frank, Oppermann, Udo, McDonough, Michael A, Doherty, Aidan and Schofield, Christopher J (2014) Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510. pp. 422-426. ISSN 0028-0836

Kuron, Aneta, Korycka-Machala, Malgorzata, Brzostek, Anna, Nowosielski, Marcin, Doherty, Aidan, Dziadek, Bożena and Dziadek, Jaroslaw (2014) Evaluation of DNA primase DnaG as a potential target for antibiotics. Antimicrobial Agents and Chemotherapy, 58 (3). pp. 1699-1706. ISSN 1098-6596

Keen, Benjamin A, Bailey, Laura, Jozwiakowski, Stanislaw and Doherty, Aidan J (2014) Human PrimPol mutation associated with high myopia has a DNA replication defect. Nucleic Acids Research, 42 (19). pp. 12102-12111. ISSN 0305-1048

Keen, Benjamin A, Jozwiakowski, Stanislaw K, Bailey, Laura J, Bianchi, Julie and Doherty, Aidan J (2014) Molecular dissection of the domain architecture and catalytic activities of human PrimPol. Nucleic Acids Research, 42 (9). pp. 5830-5845. ISSN 0305-1048

Rudd, Sean G, Glover, Lucy, Jozwiakowski, Stanislaw K, Horn, David and Doherty, Aidan J (2013) PPL2 translesion polymerase is essential for the completion of chromosomal DNA replication in the African trypanosome. Molecular Cell, 52 (4). pp. 554-565. ISSN 1097-2765

Bianchi, Julie, Rudd, Sean G, Jozwiakowski, Stanislaw K, Bailey, Laura J, Soura, Violetta, Taylor, Elaine, Stevanovic, Irena, Green, Andrew J, Stracker, Travis H, Lindsay, Howard D and Doherty, Aidan J (2013) PrimPol bypasses UV photoproducts during eukaryotic chromosomal DNA replication. Molecular Cell, 52 (4). pp. 566-573. ISSN 1097-2765

Brissett, Nigel C, Martin, Maria J, Bartlett, Edward J, Bianchi, Julie, Blanco, Luis and Doherty, Aidan J (2013) Molecular basis for DNA double-strand break annealing and primer extension by a NHEJ DNA polymerase. Cell Reports, 5 (4). pp. 1108-1120. ISSN 2211-1247

Bartlett, Edward, Brissett, Nigel C and Doherty, Aidan J (2013) Ribonucleolytic resection is required for repair of strand displaced nonhomologous end-joining intermediates. Proceedings of the National Academy of Sciences, 110 (22). E1984-E1991. ISSN 1091-6490

Brissett, Nigel C, Martin, Maria J, Pitcher, Robert S, Bianchi, Julie, Juarez, Raquel, Green, Andrew J, Fox, Gavin C, Blanco, Luis and Doherty, Aidan J (2011) Structure of a preternary complex involving a prokaryotic NHEJ DNA polymerase. Molecular Cell, 41 (2). pp. 221-231. ISSN 1097-2765

Wright, Douglas, DeBeaux, Aaustin, Shi, Runhua, Doherty, Aidan J and Harrison, Lynn (2010) Characterization of the roles of the catalytic domains of Mycobacterium tuberculosis ligase D in Ku-dependent error-prone DNA end joining. Mutagenesis, 25 (5). pp. 473-481. ISSN 0267-8357

Bailey, Sarah G, Verrall, Elizabeth, Schelcher, Celine, Rhie, Alex, Doherty, Aidan J and Sinclair, Alison J (2009) Functional interaction between Epstein-Barr virus replication protein Zta and host DNA damage response protein 53BP1. Journal of Virology, 83 (21). pp. 11116-11122. ISSN 0022-538X

Eliezer, Yifat, Argaman, Liron, Rhie, Alexandre, Doherty, Aidan J and Goldberg, Michal (2009) The direct interaction between 53BP1 and MDC1 is required for the recruitment of 53BP1 to sites of damage. Journal of Biological Chemistry, 284 (1). pp. 426-435. ISSN 0021-9258

Brissett, Nigel C, Pitcher, Robert S, Juarez, Raquel, Picher, Angel J, Green, Andrew J, Dafforn, Timothy R, Fox, Gavin C, Blanco, Luis and Doherty, Aidan J (2007) Structure of a polymerase-mediated DNA NHEJ synaptic complex. Science, 318. pp. 456-459. ISSN 0028-0836

Pitcher, R. S., Green, A. J., Brzostek, A., Korycka-Machala, M., Dziadek, J. and Doherty, A. J. (2007) NHEJ protects mycobacteria in stationary phase against the harmful effects of desiccation. DNA Repair, 6 (9). pp. 1271-1276. ISSN 0144-8420

Pitcher, Robert S, Green, Andrew J, Brzostek, Anna, Korycka-Machala, Malgorzata, Dziadek, Jaroslaw and Doherty, Aidan J (2007) NHEJ protects mycobacteria in stationary phase against the harmful effects of desiccation. DNA Repair, 6 (9). pp. 1271-1276. ISSN 1568-7864

Pitcher, R S, Brissett, N, Picher, A J, Andrade, P, Juarez, R, Thompson, D, Fox, G C, Blanco, L and Doherty, A J (2007) Structure and Function of a Mycobacterial NHEJ DNA Repair Polymerase. Journal of Molecular Biology, 366 (2). pp. 391-405. ISSN 0022-2836

Dhir, Vivek, Ivison, Hannah E, Krone, Nils, Shackleton, Cedric H L, Doherty, Aidan J, Stewart, Paul M and Arlt, Wiebke (2007) Differential Inhibition of CYP17A1 and CYP21A2 Activities by the P450 Oxidoreductase Mutant A287P. Molecular Endocrinology, 21 (8). pp. 1958-1968. ISSN 0888-8809

Malyarchuk, Svitlana, Wright, Douglas, Castore, Reneau, Klepper, Emily, Weiss, Bernard, Doherty, Aidan J and Harrison, Lynn (2007) Expression of Mycobacterium tuberculosis Ku and Ligase D in Escherichia coli results in recA-independent DNA end-joining at regions of microhomology. DNA repair, 6 (10). pp. 1413-1424. ISSN 1568-7864

Pitcher, Robert S, Brissett, Nigel C and Doherty, Aidan J (2007) Nonhomologous end-joining in bacteria: a microbial perspective. Annual Review of Microbiology, 61. pp. 258-282. ISSN 0066-4227

Moeller, Ralf, Stackebrandt, Erko, Reitz, Günther, Berger, Thomas, Rettberg, Petra, Doherty, Aidan J, Horneck, Gerda and Nicholson, Wayne L (2007) Role of DNA Repair by Nonhomologous-End Joining in Bacillus subtilis Spore Resistance to Extreme Dryness, Mono- and Polychromatic UV, and Ionizing Radiation. Journal of Bacteriology, 189 (8). pp. 3306-3311. ISSN 0021-9193

Palecek, Jan, Vidot, Susanne, Feng, Min, Doherty, Aidan J and Lehmann, Alan R (2006) The Smc5-Smc6 DNA Repair Complex: BRIDGING OF THE Smc5-Smc6 HEADS BY THE KLEISIN, Nse4,AND NON-KLEISIN SUBUNITS. Journal of Biological Chemistry, 281 (48). pp. 36952-36959. ISSN 0021-9258

Hentges, P., Ahnesorg, P., Pitcher, R. S., Bruce, C. K., Kysela, B., Green, A. J., Bianchi, J., Wilson, T. E., Jackson, S. P. and Doherty, A. J. (2006) Evolutionary and functional conservation of the DNA non homologous end joining protein, XLF/Cernunnos. Journal of Biological Chemistry, 281 (49). pp. 37517-37526. ISSN 0021-9258

Pitcher, Robert S, Tonkin, Louise M, Daley, James M, Palmbos, Phillip L, Green, Andrew, Velting, Tricia L, Brzostek, Anna, Korycka-Machala, Malgorzata, Cresawn, Steve, Dziadek, Jaroslaw, Hatfull, Graham F, Wilson, Thomas E and Doherty, Aidan J (2006) Mycobacteriophage exploit NHEJ to facilitate genome circularization. Molecular Cell, 23 (5). pp. 743-748. ISSN 1097-2765

Marchetti, Caterina, Walker, Sarah A, Odreman, Federico, Vindigni, Alessandro, Doherty, Aidan J and Jeggo, Penny (2006) Identification of a novel motif in DNA ligases exemplified by DNA ligase IV. DNA Repair, 5 (7). pp. 788-798. ISSN 1568-7864

Hentges, Pierre, Ahnesorg, Peter, Pitcher, Robert S, Bruce, Chris K, Kysela, Boris, Green, Andrew J, Bianchi, Julie, Wilson, Thomas E, Jackson, Stephen P and Doherty, Aidan J (2006) Evolutionary and functional conservation of the DNA non homologous end joining protein, XLF/Cernunnos. Journal of Biological Chemistry, 281 (49). pp. 37517-37526. ISSN 0021-9258

Bowater, R. and Doherty, A. J. (2006) Making ends meet: repairing breaks in bacterial DNA by non-homologous end-joining. PLoS Genetics, 2 (2). ISSN 1553-7404

Bowater, Richard and Doherty, Aidan J (2006) Making ends meet: repairing breaks in bacterial DNA by non-homologous end-joining. PLoS Genetics, 2 (2). e8. ISSN 1553-7404

Doherty, Aidan, Palecek, Jan, Vidot, Susanne, Feng, Min and Lehmann, AR (2006) Nse4 is the kleisin component of the Smc5-6 DNA repair complex. Biological Chemistry, 281. pp. 36952-36959. ISSN 1431-6730

Palecek, J., Vidot, S., Feng, M., Doherty, A. J. and Lehmann, A. R. (2006) The SMC5-6 DNA repair complex: Bridging of the SMC5-6 heads by the Kleisin, NSE4, and non-Kleisin subunits. Journal of Biological Chemistry, 2006 D (48). pp. 36952-36959. ISSN 0021-9258

Boisvert, François-Michel, Rhie, Alexandre, Richard, Stéphane and Doherty, Aidan J (2005) The GAR motif of 53BP1 is a target for PRMT1 methylation and directs chromatin localisation in response to DNA damage. Cell Cycle, 4 (12). pp. 1834-1841. ISSN 1538-4101

Chavali, Gayatri B, Ekblad, Caroline M S, Basu, Balaka P, Brissett, Nigel C, Veprintsev, Dmitry, Hughes-Davies, Luke, Kouzarides, Tony, Itzhaki, Laura S and Doherty, Aidan J (2005) Crystal structure of the ENT domain of human EMSY. Journal of Molecular Biology, 350 (5). pp. 964-973. ISSN 0022-2836

Pitcher, Robert S, Wilson, Thomas E and Doherty, Aidan J (2005) New insights into NHEJ repair processes in prokaryotes. Cell Cycle, 4 (5). pp. 675-678. ISSN 1551-4005

Ekblad, Caroline M S, Chavali, Gayatri B, Basu, Balaka P, Freund, Stefan M V, Veprintsev, Dmitry, Hughes-Davies, Luke, Kouzarides, Tony, Doherty, Aidan J and Itzhaki, Laura S (2005) Binding of EMSY to HP1beta: implications for recruitment of HP1beta and BS69. EMBO Reports, 6 (7). pp. 675-680. ISSN 1469-221X

Gissen, Paul, Johnson, Colin A, Gentle, Dean, Hurst, Laurence D, Doherty, Aidan J, O'Kane, Cahir J, Kelly, Deirdre A and Maher, Eamonn R (2005) Comparative evolutionary analysis of VPS33 homologues: genetic and functional insight. Human Molecular Genetics, 14 (10). pp. 1261-1270. ISSN 0964-6906

Gissen, Paul, Johnson, Colin A., Gentle, Dean, Hurst, Laurence D., Doherty, Aidan J., O'Kane, Cahir J., Kelly, Deirdre A. and Maher, Eamonn R. (2005) Comparative evolutionary analysis of VPS33 homologues: genetic and functional insights. Human Molecular Genetics, 14 (10). pp. 1261-1270. ISSN 0964-6906

Chavali, Gayatri B., Ekblad, Caroline M.S., Basu, Balaka P., Brissett, Nigel C., Veprintsev, Dmitry, Hughes-Davies, Luke, Kouzarides, Tony, Itzhaki, Laura S. and Doherty, Aidan J. (2005) Crystal structure of the ENT domain of human EMSY. Journal of Molecular Biology, 350 (5). pp. 964-73. ISSN 0022-2836

Pitcher, Robert S., Tonkin, Louise M., Green, Andrew J. and Doherty, Aidan J. (2005) Domain structure of a NHEJ DNA repair ligase from Mycobacterium tuberculosis. Journal of Molecular Biology, 351 (3). pp. 531-44. ISSN 0022-2836

Pitcher, Robert S, Tonkin, Louise M, Green, Andrew J and Doherty, Aidan J (2005) Domain structure of a NHEJ DNA repair ligase from Mycobacterium tuberculosis. Journal of Molecular Biology, 351 (3). pp. 531-544. ISSN 1551-4005

Pitcher, R. S., Wilson, T. E. and Doherty, A. J. (2005) New insights into NHEJ repair processes in prokaryotes. Cell Cycle, 4 (5). pp. 675-8. ISSN 1551-4005

Jowsey, Paul A, Doherty, Aidan J and Rouse, John (2004) Human PTIP Facilitates ATM-mediated Activation of p53 and Promotes Cellular Resistance to Ionizing Radiation. Journal of Biological Chemistry, 279 (53). pp. 55562-55569. ISSN 0021-9258

Riballo, Enriqueta, Kühne, Martin, Rief, Nicole, Doherty, Aidan, Smith, Graeme C M, Recio, Marı́a-José, Reis, Caroline, Dahm, Kirsten, Fricke, Andreas, Krempler, Andrea, Parker, Antony R, Jackson, Stephen P, Gennery, Andrew, Jeggo, Penny A and Löbrich, Markus (2004) A Pathway of Double-Strand Break Rejoining Dependent upon ATM, Artemis, and Proteins Locating to ¿-H2AX Foci. Molecular Cell, 16 (5). pp. 715-724. ISSN 1097-2765

Della, Marina, Palmbos, Phillip L, Tseng, Hui-Min, Tonkin, Louise M, Daley, James M, Topper, Leana M, Pitcher, Robert S, Tomkinson, Alan E, Wilson, Thomas E and Doherty, Aidan J (2004) Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science, 306 (5696). pp. 683-685. ISSN 0036-8075

Girard, Pierre-Marie, Kysela, Boris, Harer, Christine J., Doherty, Aidan J. and Jeggo, Penny A. (2004) Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms. Human Molecular Genetics, 13 (20). pp. 2369-76. ISSN 0964-6906

Girard, Pierre-Marie, Kysela, Boris, Härer, Christine J, Doherty, Aidan J and Jeggo, Penny A (2004) Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms. Human Molecular Genetics, 13 (20). pp. 2369-2376. ISSN 0964-6906

Englander, J., Klein, E., Brumfeld, V., Sharma, A. K., Doherty, A. J. and Minsky, A. (2004) DNA toroids: framework for DNA repair in Deinococcus radiodurans and in germinating bacterial spores. Journal of Bacteriology, 186 (18). pp. 5973-7. ISSN 5973-5977

Englander, Joseph, Klein, Eugenia, Brumfeld, Vlad, Sharma, Ajay K, Doherty, Aidan J and Minsky, Abraham (2004) DNA toroids: framework for DNA repair in Deinococcus radiodurans and in germinating bacterial spores. Journal of Bacteriology, 186 (18). pp. 5973-5977. ISSN 5973-5977

Jowsey, Paul A., Doherty, Aidan J. and Rouse, John (2004) Human PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. Journal of Biological Chemistry, 279 (53). pp. 55562-9. ISSN 0021-9258

Della, M., Palmbos, P. L., Tseng, H. M., Tonkin, L. M., Daley, J. M., Topper, L. M., Pitcher, R. S., Tomkinson, A. E., Wilson, T. E. and Doherty, A. J. (2004) Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science, 306 (5696). pp. 683-5. ISSN http://eprints.sussex.ac.uk/570/

Jowsey, Paul A., Doherty, Aidan J. and Rouse, John (2004) hPTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionising radiation. Journal of Biological Chemistry, 279 (53). pp. 55562-55569. ISSN 0021-9258

Riballo, E., Kuhne, M., Rief, N., Doherty, A. J., Smith, G. C. M., Recio, M-J., Reis, C., Dahm, K., Fricke, A., Krempler, A., Parker, A. R., Jackson, S. P., Gennery, A. R., Jeggo, P. A. and Lobrich, M. (2004) A pathway of double strand break rejoining dependent upon ATM, Artemis and proteins locating to g-H2AX foci. Molecular Cell, 16. pp. 715-724. ISSN 1097-2765

Iwabuchi, K., Basu, B. P., Kysela, B., Kurihara, T., Shibata, M., Guan, D., Cao, Y., Hamada, T., Imamura, K., Jeggo, P. A., Date, T. and Doherty, A. J. (2003) Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. Journal of Biological Chemistry, 278 (38). pp. 36487-36495. ISSN 0021-9258

Iwabuchi, Kuniyoshi, Basu, Balaka Piku, Kysela, Boris, Kurihara, Takayuki, Shibata, Masao, Guan, Deyu, Cao, Yongheng, Hamada, Tomio, Imamura, Kouji, Jeggo, Penny A, Date, Takayasu and Doherty, Aidan J (2003) Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. Journal of Biological Chemistry, 278 (38). pp. 36487-36495. ISSN 0021-9258

Hughes-Davies, L., Huntsman, D., Ruas, M., Fuks, F., Bye, J., Chin, S. F., Milner, J., Brown, L. A., Hsu, F., Gilks, B., Nielsen, T., Schulzer, M., Chia, S., Ragaz, J., Cahn, A., Linger, L., Ozdag, H., Cattaneo, E., Jordanova, E. S., Schuuring, E., Yu, D. S., Venkitaraman, A., Ponder, B., Doherty, A., Aparicio, S., Bentley, D., Theillet, C., Ponting, C. P., Caldas, C. and Kouzarides, T. (2003) EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell, 115 (5). pp. 523-35. ISSN 0092-8674

Hughes-Davies, Luke, Huntsman, David, Ruas, Margarida, Fuks, Francois, Bye, Jacqueline, Chin, Suet-Feung, Milner, Jonathon, Brown, Lindsay A, Hsu, Forrest, Gilks, Blake, Nielsen, Torsten, Schulzer, Michael, Chia, Stephen, Ragaz, Joseph, Cahn, Anthony, Linger, Lori, Ozdag, Hilal, Cattaneo, Elena, Jordanova, E S, Schuuring, Edward, Yu, David S, Venkitaraman, Ashok, Ponder, Bruce, Doherty, Aidan, Aparicio, Samuel, Bentley, David, Theillet, Charles, Ponting, Chris P, Caldas, Carlos and Kouzarides, Tony (2003) EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell, 115 (5). pp. 523-535. ISSN 0092-8674

d'Adda di Fagagna, Fabrizio, Weller, Geoffrey R, Doherty, Aidan J and Jackson, Stephen P (2003) The Gam protein of phage Mu is an orthologue of eukaryotic Ku. EMBO Reports, 4 (1). pp. 47-52. ISSN 1469-221X

Kysela, Boris, Doherty, Aidan J, Chovanec, Miroslav, Stiff, Thomas, Ameer-Beg, Simon M, Vojnovic, Borivoj, Girard, Pierre-Marie and Jeggo, Penny A (2003) Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule. Journal of Biological Chemistry, 278 (25). pp. 22466-22474. ISSN 0021-9258

Dionne, Isabelle, Nookala, Ravi K, Jackson, Stephen P, Doherty, Aidan J and Bell, Stephen D (2003) The heterotrimeric PCNA of the hyperthermophilic archaeon Sulfolobus solfatricus: implications for the clamp loading mechanism. Molecular Cell, 11 (1). pp. 275-282. ISSN 1097-2765

Doherty, Aidan, Kysela, Boris, Jeggo, Penny, Iwabuchi, K, Basu, BP and Kurihara, T (2003) p53-binding protein 1 (53BP1) binds to DNA at IR damage-induced foci and promotes DNA double-strand break repair. Journal of Biological Chemistry, 278. pp. 36487-36495. ISSN 0021-9258

Derbyshire, D J, Basu, B P, Date, T, Iwabuchi, K and Doherty, A J (2002) Purification, crystallization and preliminary X-ray analysis of a complex of the BRCT domains of human 53BP1 bound to the p53 tumour suppressor. Acta Crystallographica Section D: Biological Crystallography, 58-10 (2). pp. 1826-1829. ISSN 0907-4449

Weller, Geoffery R, Kysela, Boris, Roy, Rajat, Tonkin, Louise M, Scanlan, Elizabeth, Della, Marina, Devine, Susanne Krogh, Day, Jonathan P, Wilkinson, Adam, d'Adda di Fagagna, Fabrizio, Devine, Kevin M, Bowater, Richard P, Jeggo, Penny A, Jackson, Stephen P and Doherty, Aidan J (2002) Identification of a DNA nonhomologous end-joining complex in bacteria. Science, 297. pp. 1686-1689. ISSN 0036-8075

Derbyshire, Dean J, Basu, Balaku P, Serpell, Louise C, Joo, Woo S, Date, Takayasu, Iwabuchi, Kuniyoshi and Doherty, Aidan J (2002) Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor. EMBO Journal, 21 (14). pp. 3863-3872. ISSN 0261-4189

Doherty, Aidan J and Jackson, Stephen P (2001) DNA repair: How Ku makes ends meet. Current Biology, 11 (22). R920-R924. ISSN 0960-9822

Riballo, Enriqueta, Doherty, Aidan J, Dai, Yan, Stiff, Thomas, Oettinger, Marjorie A, Jeggo, Penny A and Kysela, Boris (2001) Cellular and biochemical impact of a mutation in DNA ligase IV conferring clinical radiosensitivity. Journal of Biological Chemistry, 276. pp. 31124-31132. ISSN 0021-9258

Doherty, Aidan J, Jackson, Stephen P and Weller, Geoffrey R (2001) Identification of bacterial homologues of the Ku DNA repair proteins. FEBS Letters, 500 (3). pp. 186-188. ISSN 0014-5793

Weller, Geoffery R and Doherty, Aidan J (2001) A family of DNA repair ligases in bacteria? FEBS Letters, 505 (2). pp. 340-342. ISSN 0014-5793

Riballo, E, Critchlow, S E, Teo, S-H, Doherty, A J, Priestley, A, Broughton, B, Kysela, B, Beamish, H, Plowman, N, Arlett, C F, Lehmann, A R, Jackson, S P and Jeggo, P A (1999) Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient. Current Biology, 9 (13). 699 - 702. ISSN 0960-9822

Conference or Workshop Item

Brissett, Nigel C and Doherty, Aidan J (2009) Repairing DNA double-strand breaks by the prokaryotic non-homologous end-joining pathway. In: Symposium on DNA Damage - From Causes to Cures, Univ Cambridge, Robinson Coll, Cambridge, ENGLAND, DEC 15-17, 2008.

This list was generated on Tue Nov 21 04:09:04 2017 GMT.