Items for El-Khamisy, Sherif

Up a level
Export as [feed] RSS
Group by: Item Type | No Grouping
Number of items: 27.

Article

Carroll, Jean, Page, Tristan K W, Chiang, Shih-Chieh, Kalmar, Bernadett, Bode, David, Greensmith, Linda, Mckinnon, Peter J, Thorpe, Julian R, Hafezparast, Majid and El-Khamisy, Sherif F (2015) Expression of a pathogenic mutation of SOD1 sensitizes aprataxin-deficient cells and mice to oxidative stress and triggers hallmarks of premature ageing. Human Molecular Genetics, 24 (3). pp. 828-40. ISSN 1460-2083

Walker, Sarah, Meisenberg, Cornelia, Bibby, Rachel A, Askwith, Trevor, Williams, Gareth, Rininsland, Frauke H, Pearl, Laurence H, Oliver, Antony W, El-Khamisy, Sherif, Ward, Simon and Atack, John R (2014) Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. Analytical Biochemistry, 454. pp. 17-22. ISSN 0003-2697

Alagoz, Meryem, Wells, Owen S and El-Khamisy, Sherif F (2014) TDP1 deficiency sensitizes human cells to base damage via distinct topoisomerase I and PARP mechanisms with potential applications for cancer therapy. Nucleic Acids Research, 42 (5). pp. 3089-3103. ISSN 0305-1048

Alagoz, Meryem, Chiang, Shih-Chieh, Sharma, Abhishek and El-Khamisy, Sherif F (2013) ATM deficiency results in accumulation of DNA-Topoisomerase I covalent intermediates in neural cells. PLoS ONE, 8 (4). e58239. ISSN 1932-6203

Hudson, Jessica J R, Chiang, Shih-Chieh, Wells, Owen S, Rookyard, Chris and El-Khamisy, Sherif F (2012) SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair. SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair., 3. p. 733. ISSN 2041-1723

Zeng, Z, Sharma, A, Ju, L, Murai, J, Umans, L, Vermeire, L, Pommier, Y, Takeda, S, Huylebroeck, D, Caldecott, K and El-Khamisy, S (2012) TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1. Nucleic Acids Research, 40 (17). pp. 8371-8380. ISSN 1362-4962

El-Khamisy, Sherif (2011) To live or to die: a matter of processing damaged DNA termini in neurons. EMBO Molecular Medicine, 3 (2). pp. 78-88. ISSN 17574676

Zeng, Zhihong, Cortes-Ledesma, Felipe, El-Khamisy, Sherif and Caldecott, Keith W (2010) TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damage. Journal of Biological Chemistry, 286 (1). pp. 403-409. ISSN 0021-9258

El-Khamisy, Sherif, Chiang, Shih-Chieh and Carroll, John (2010) TDP1 serine 81 promotes interaction with DNA ligase IIIalpha and facilitates cell survival following DNA damage. Cell Cycle, 9 (3). pp. 588-595. ISSN 15384101

Cortes Ledesma, Felipe, El-Khamisy, Sherif F, Zuma, Maria C, Osborn, Kay and Caldecott, Keith W (2009) A human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damage. Nature, 461 (7264). pp. 674-678. ISSN 0028-0836

Lee, Youngsoo, Katyal, Sachin, Li, Yang, El-Khamisy, Sherif F, Russell, Helen R, Caldecott, Keith W and McKinnon, Peter J (2009) The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nature Neuroscience, 12 (8). 973-U35. ISSN 1097-6256

El-Khamisy, Sherif F, Katyal, Sachin, Patel, Poorvi, Ju, Limei, McKinnon, Peter J and Caldecott, Keith W (2009) Synergistic decrease of DNA single-strand break repair rates in mouse neural cells lacking both Tdp1 and aprataxin. DNA Repair, 8 (6). pp. 760-766. ISSN 1568-7864

Reynolds, John J, El-Khamisy, Sherif F, Katyal, Sachin, Clements, Peter, McKinnon, Peter J and Caldecott, Keith W (2009) Defective DNA ligation during short-patch single-strand break repair in ataxia oculomotor apraxia 1. Molecular and Cellular Biology, 29 (5). pp. 1354-1362. ISSN 0270-7306

Katyal, Sachin, El-Khamisy, Sherif F, Russell, Helen R, Liu, Yang, Ju, Limei, Caldecott, Keith W and McKinnon, Peter J (2007) TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. EMBO Journal, 26. pp. 4720-4731. ISSN 0261-4189

El-Khamisy, Sherif F, Hartsuiker, Edgar and Caldecott, Keith W (2007) TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks. DNA Repair, 6 (10). pp. 1485-1495. ISSN 1568-7864

Iles, Natasha, Rulten, Stuart, El-Khamisy, Sherif F and Caldecott, Keith W (2007) APLF (C2orf13) Is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks. Molecular and Cellular Biology, 27 (10). pp. 3793-3803. ISSN 0270-7306

Iles, Natasha, Rulten, Stuart L., El-Khamisy, Sherif F. and Caldecott, Keith W. (2007) APLF (C2orf13) is a Novel Human Protein Involved in the Cellular Response to Chromosomal DNA Strand Breaks. Molecular and Cellular Biology, 27 (10). pp. 3793-3803. ISSN 0270-7306

El-Khamisy, S F and Caldecott, K W (2007) DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1. Neuroscience, 145 (4). pp. 1260-1266. ISSN 0306-4522

El-Khamisy, Sherif F and Caldecott, Keith W (2006) TDP1-dependent DNA single-strand break repair and neurodegeneration. Mutagenesis, 21 (4). pp. 219-224. ISSN 0267-8357

Ahel, Ivan, Rass, Ulrich, El-Khamisy, Sherif F, Katyal, Sachin, Clements, Paula M, McKinnon, Peter J, Caldecott, Keith W and West, Stephen C (2006) The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates. Nature, 443. pp. 713-716. ISSN 0028-0836

Breslin, Claire, Clements, Paula M, El-Khamisy, Sherif F, Petermann, Eva, Iles, Natasha and Caldecott, Keith W (2006) Measurement of chromosomal DNA single-strand breaks and replication fork progression rates. Methods in Enzymology, 409. pp. 410-425. ISSN 0076-6879

El-Khamisy, Sherif F, Saifi, Gulam M, Weinfeld, Michael, Johansson, Fredrik, Helleday, Thomas, Lupski, James R and Caldecott, Keith W (2005) Defective DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1. Nature, 434. pp. 108-113. ISSN 0306-4522

El-Khamisy, Sherif F, Saifi, Gulam M, Weinfeld, Michael, Johansson, Fredrik, Helleday, Thomas, Lupski, James R and Caldecott, Keith W (2005) Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1. Nature, 434. pp. 108-113. ISSN 0028-0836

El-Khamisy, S. F., Saifi, G. M., Weinfeld, M., Johansson, F., Helleday, T., Lupski, J. R. and Caldecott, K. W. (2005) Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1. Nature, 434 (7029). pp. 108-13. ISSN 1476-4687

Loizou, Joanna I, El-Khamisy, Sherif F, Zlatanou, Anastasia, Moore, David J, Chan, Douglas W, Qin, Jun, Sarno, Stefania, Meggio, Flavio, Pinna, Lorenzo A and Caldecott, Keith W (2004) The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks. Cell, 117 (1). pp. 17-28. ISSN 0092-8674

Book Section

Wells, Owen Spencer and El-Khamisy, Sherif F (2014) Autosomal recessive ataxias due to defects in DNA repair. In: LeDoux, Mark S (ed.) Movement Disorders, 2nd Edition. Elsevier, London. ISBN 9780124051959

Conference or Workshop Item

Reynolds, John J, El-Khamisy, Sherif F and Caldecott, Keith W (2009) Short-patch single-strand break repair in ataxia oculomotor apraxia-1. In: Symposium on DNA Damage - From Causes to Cures Univ Cambridge, Robinson Coll, Cambridge, ENGLAND, DEC 15-17, 2008, Cambridge, ENGLAND.

This list was generated on Sat Mar 25 09:38:27 2017 GMT.