Items for Oliver, Antony

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Article

Alt, Aaron, Dang, Hung Q, Wells, Owen S, Polo, Luis M, Smith, Matt A, McGregor, Grant A, Welte, Thomas, Lehmann, Alan R, Pearl, Laurence H, Murray, Johanne M and Oliver, Antony W (2017) Specialized interfaces of Smc5/6 control hinge stability and DNA association. Nature Communications, 8. p. 14011. ISSN 2041-1723

Ocasio, Cory A, Rajasekaran, Mohan B, Walker, Sarah, Le Grand, Darren, Spencer, John, Pearl, Frances M G, Ward, Simon E, Savic, Velibor, Pearl, Laurence H, Hochegger, Helfrid and Oliver, Antony W (2016) A first generation inhibitor of human Greatwall kinase, enabled by structural and functional characterisation of a minimal kinase domain construct. Oncotarget, 7 (44). 71182 -71197. ISSN 1949-2553

Grundy, Gabrielle J, Polo, Luis M, Zeng, Zhihong, Rulten, Stuart, Hoch, Nicolas, Pathompong, Paomephan, Xu, Yingqi, Sweet, Steve M, Thorne, Alan W, Oliver, Antony W, Matthews, Steve J, Pearl, Laurence H and Caldecott, Keith W (2016) PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2). Nature Communications, 7 (12404). ISSN 2041-1723

van der Crabben, Saskia N, Hennus, Marije P, McGregor, Grant, Ritter, Deborah I, Nagamani, Sandesh C S, Wells, Owen S, Harakalova, Magdalena, Chinn, Ivan K, Alt, Aaron, Vondrova, Lucie, Hochstenbach, Ron, van Montfrans, Joris M, Terheggen-Lagro, Suzanne W, van Lieshout, Stef, van Roosmalen, Markus J, Renkens, Ivo, Duran, Karen, Nijman, Isaac J, Kloosterman, Wigard P, Hennekam, Eric, Orange, Jordan S, van Hasselt, Peter M, Wheeler, David A, Palecek, Jan J, Lehmann, Alan R, Oliver, Antony W, Pearl, Laurence H, Plon, Sharon E, Murray, Johanne M and van Haaften, Gijs (2016) Destabilized SMC5/6 complex leads to chromosome breakage syndrome with severe lung disease. Journal of Clinical Investigation, 126 (8). pp. 2881-2892. ISSN 0021-9738

Hornyak, Peter, Askwith, Trevor, Walker, Sarah, Komulainen, Emilia, Paradowski, Michael, Pennicott, Lewis E, Bartlett, Edward J, Brissett, Nigel C, Raoof, Ali, Watson, Mandy, Jordan, Allan M, Ogilvie, Donald J, Ward, Simon E, Atack, John R, Pearl, Laurence H, Caldecott, Keith W and Oliver, Antony W (2016) Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2. Biochemical Journal, 473 (13). pp. 1869-1879. ISSN 0264-6021

Grundy, Gabrielle J, Rulten, Stuart L, Arribas-Bosacoma, Raquel, Davidson, Kathryn, Kozik, Zuzanna, Oliver, Antony W, Pearl, Laurence H and Caldecott, Keith W (2016) The Ku-binding motif is a conserved module for recruitment and stimulation of non-homologous end-joining proteins. Nature Communications, 7. a11242. ISSN 2041-1723

Zabrady, Katerina, Adamus, Marek, Vondrova, Lucie, Liao, Chunyan, Skoupilova, Hana, Novakova, Marketa, Jurcisinova, Lenka, Alt, Aaron, Oliver, Antony W, Lehmann, Alan R and Palecek, Jan J (2016) Chromatin association of the SMC5/6 complex is dependent on binding of its NSE3 subunit to DNA. Nucleic Acids Research, 44 (3). pp. 1064-1079. ISSN 1362-4962

McKinnon, Peter, Byrd, Philip J, Stewart, Grant. S, Smith, Anna, Eaton, Charlotte, Taylor, Alexander J, Guy, Chloe, Eringyte, Ieva, Fooks, Peggy, Last, James I, Horsley, Robert, Oliver, Antony W, Janic, Dragana, Dokmanovic, Lidija, Stankovic, Tatjana and Taylor, A Malcolm R (2016) A hypomorphic PALB2 allele gives rise to an unusual form of FA-N associated with lymphoid tumour development. PLOS Genetics, 12 (3). e1005945. ISSN 1553-7404

Donato, Nataliya Di, Rump, Andreas, Mirzaa, Ghayda M, Alcantara, Diana, Oliver, Antony, Schrock, Evelin, Dobyns, William B and O'Driscoll, Mark (2015) Identification and characterisation of a novel constitutional PIK3CA mutation in a child lacking the typical segmental overgrowth of "PIK3CA-Related Overgrowth Spectrum" (PROS). Human Mutation, 37 (3). pp. 242-245. ISSN 1059-7794

Baldock, Robert A, Day, Matthew, Wilkinson, Oliver J, Cloney, Ross, Jeggo, Penelope A, Oliver, Antony W, Watts, Felicity Z and Pearl, Laurence H (2015) ATM localization and heterochromatin repair depend on Direct Interaction of the 53BP1-BRCT2 domain with γH2AX. Cell Reports, 13 (10). pp. 2081-2089. ISSN 2211-1247

Robinson, Sophie R, Oliver, Antony W, Chevassut, Timothy J and Newbury, Sarah F (2015) The 3' to 5' exoribonuclease DIS3: from structure and mechanisms to biological functions and role in human disease. Biomolecules, 5 (3). pp. 1515-1539. ISSN 2218-273X

Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L, Hanzlikova, Hana, Oliver, Antony W and Caldecott, Keith W (2015) The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function. Nucleic Acids Research, 43 (14). pp. 6934-6944. ISSN 0305-1048

Wardlaw, Christopher P, Carr, Antony M and Oliver, Antony W (2014) TopBP1: A BRCT-scaffold protein functioning in multiple cellular pathways. DNA Repair, 22. pp. 165-174. ISSN 1568-7864

Walker, Sarah, Meisenberg, Cornelia, Bibby, Rachel A, Askwith, Trevor, Williams, Gareth, Rininsland, Frauke H, Pearl, Laurence H, Oliver, Antony W, El-Khamisy, Sherif, Ward, Simon and Atack, John R (2014) Development of an oligonucleotide-based fluorescence assay for the identification of tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors. Analytical Biochemistry, 454. pp. 17-22. ISSN 0003-2697

Fontebasso, Y, Etheridge, T J, Oliver, A W, Murray, J M and Carr, A M (2013) The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast. DNA Repair, 12 (12). pp. 1011-1023. ISSN 15687864

Chambers, Anna L, Pearl, Laurence H, Oliver, Antony W and Downs, Jessica A (2013) The BAH domain of Rsc2 is a histone H3 binding domain. Nucleic Acids Research, 41 (19). pp. 9168-9182. ISSN 0305-1048

Silva-Santisteban, M Cris, Westwood, Isaac M, Boxall, Kathy, Brown, Nathan, Peacock, Sam, McAndrew, Craig, Barrie, Elaine, Richards, Meirion, Mirza, Amin, Oliver, Antony W, Burke, Rosemary, Hoelder, Swen, Jones, Keith, Aherne, G Wynne, Blagg, Julian, Collins, Ian, Garrett, Michelle D and van Montfort, Rob L M (2013) Fragment-based screening maps inhibitor interactions in the ATP-binding site of checkpoint kinase 2. PLoS ONE, 8 (6). e65689. ISSN 1932-6203

Grundy, Gabrielle L, Rulten, Stuart L, Zeng, Zhihong, Arribas-Bosacoma, Raquel, Iles, Natasha, Manley, Katie, Oliver, Antony and Caldecott, Keith W (2013) APLF promotes the assembly and activity of non-homologous end joining protein complexes. The EMBO journal, 32 (1). pp. 112-125. ISSN 1460-2075

Qu, Meng, Rappas, Mathieu, Wardlaw, Christopher P, Garcia, Valerie, Ren, Jing-Yi, Day, Matthew, Carr, Antony M, Oliver, Antony, Du, Li-Lin and Pearl, Laurence (2013) Phosphorylation-dependent assembly and coordination of the DNA damage checkpoint apparatus by Rad4TopBP1. Molecular Cell, 51 (6). pp. 723-736. ISSN 1097-2765

Brownlee, Peter M, Chambers, Anna L, Oliver, Antony W and Downs, Jessica A (2012) Cancer and the bromodomains of BAF180. Biochemical Society Transactions, 40 (2). pp. 364-369. ISSN 0300-5127

Ali, Ammar A E, Timinszky, Gyula, Arribas-Bosacoma, Raquel, Kozlowski, Marek, Hassa, Paul O, Hassler, Markus, Ladurner, Andreas G, Pearl, Laurence H and Oliver, Antony W (2012) The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks. Nature Structural & Molecular Biology, 9 (7). pp. 685-692. ISSN 1545-9985

Garces, Fernando, Pearl, Laurence H and Oliver, Antony W (2011) The structural basis for substrate recognition by mammalian polynucleotide kinase 3' phosphatase. Molecular Cell, 44 (3). 385 - 396. ISSN 1097-2765

Boos, Dominik, Sanchez-Pulido, Luis, Rappas, Mathieu, Pearl, Laurence H, Oliver, Antony W, Ponting, Chris P and Diffley, John F X (2011) Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans. Current Biology, 21 (13). pp. 1152-1157. ISSN 0960-9822

Caldwell, John J, Welsh, Emma J, Matjissen, Cornelis, Anderson, Victoria E, Antoni, Laurent, Boxall, Kathy, Urban, Frederique, Hayes, Angela, Raynaud, Florence I, Rigoreau, Laurent J M, Raynham, Tony, Aherne, G Wynne, Pearl, Laurence H, Oliver, Antony W, Garrett, Michelle D and Collins, Ian (2011) Structure-Based Design of Potent and Selective 2-(Quinazolin-2-yl)phenol Inhibitors of Checkpoint Kinase 2. Journal of Medicinal Chemistry, 54 (2). pp. 580-590. ISSN 0022-2623

Anderson, Victoria E, Walton, Michael I, Eve, Paul D, Boxall, Katherine J, Antoni, Laurent, Caldwell, John J, Aherne, Wynne, Pearl, Laurence H, Oliver, Antony W, Collins, Ian and Garrett, Michelle D (2011) CCT241533 Is a Potent and Selective Inhibitor of CHK2 that Potentiates the Cytotoxicity of PARP Inhibitors. Cancer Research, 71 (2). pp. 463-472. ISSN 0008-5472

Rappas, Mathieu, Oliver, Antony W and Pearl, Laurence H (2011) Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1. Nucleic Acids Research, 39 (1). pp. 313-324. ISSN 0305-1048

Woodbine, Lisa, Grigoriadoub, Sofia, Goodarzi, Aaron A, Riballo, Enriqueta, Tape, Christopher, Oliver, Antony W, van Zelm, Menno C, Buckland, Matthew S, Davies, E Graham, Pearl, Laurence H and Jeggo, Penny A (2010) An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity. DNA Repair, 9 (9). pp. 1003-1010. ISSN 1568-7864

Hilton, Stephen, Naud, Sebastien, Caldwell, John J, Boxall, Kathy, Burns, Samantha, Anderson, Victoria E, Antoni, Laurent, Allen, Charlotte E, Pearl, Laurence H, Oliver, Antony W, Aherne, G Wynne, Garrett, Michelle D and Collins, Ian (2010) Identification and characterisation of 2-aminopyridine inhibitors of checkpoint kinase 2. Bioorganic & Medicinal Chemistry, 18 (2). pp. 707-718. ISSN 0968-0896

Oliver, Antony W, Swift, Sally, Lord, Christopher J, Ashworth, Alan and Pearl, Laurence H (2009) Structural basis for recruitment of BRCA2 by PALB2. EMBO Reports, 10 (9). pp. 990-996. ISSN 1469-221X

Ali, Ammar A. E., Jukes, Rachel M., Pearl, Laurence H. and Oliver, Antony W. (2009) Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK. Nucleic Acids Research, 37 (5). pp. 1701-1712. ISSN 0305-1048

Pike, Ashley C W, Rellos, Peter, Niesen, Frank H, Turnbull, Andrew, Oliver, Antony W, Parker, Sirlester A, Turk, Benjamin E, Pearl, Laurence H and Knapp, Stefan (2008) Activation segment dimerization: a mechanism for kinase autophosphorylation of non-consensus sites. EMBO Journal, 27 (4). pp. 704-714. ISSN 0261-4189

Oliver, Antony W, Knapp, Stefan and Pearl, Laurence H (2007) Activation segment exchange: a common mechanism of kinase autophosphorylation? Trends in Biochemical Science, 32 (8). pp. 351-356.

Dore, A S, Kilkenny, M L, Jones, S A, Oliver, A W, Roe, S M, Bell, S D and Pearl, L H (2006) Structure of an archaeal PCNA1-PCNA2-FEN1 complex: elucidating PCNA subunit and client enzyme specificity. Nucleic Acids Research, 34 (16). pp. 4515-4526.

Oliver, Antony W, Paul, Angela, Boxall, Katherine J, Barrie, S Elaine, Aherne, G Wynne, Garrett, Michelle D, Mittnacht, Sibylle and Pearl, Laurence H (2006) Trans-activation of the DNA-damage signalling protein kinase Chk2 by T-loop exchange. EMBO Journal, 25 (13). pp. 3179-3190. ISSN 0261-4189

Oliver, Antony W, Jones, Sarah A, Roe, Stephen Mark, Matthews, Steve, Goodwin, Graham H and Pearl, Laurence H (2005) Crystal structure of the proximal BAH domain of the polybromo protein. Biochemical Journal, 389 (3). pp. 657-664. ISSN 0264-6021

Oliver, A W, Amé, J C, Roe, S M, Good, V, de Murcia, G and Pearl, L H (2004) Crystal structure of the catalytic fragment of murine poly(ADP-ribose) polymerase-2. Nucleic Acids Research, 32 (2). pp. 456-464. ISSN 0305-1048

Oliver, Antony W, Bogdarina, Irina, Schroeder, Ewald, Taylor, Ian A and Kneale, G Geoff (2000) Preferential binding of fd gene 5 protein to tetraplex nucleic acid structures. Journal of Molecular Biology, 301 (3). pp. 575-584.

Oliver, Antony W and Kneale, G Geoff (1999) Structural characterization of DNA and RNA sequences recognized by the gene 5 protein of bacteriophage fd. Biochemical Journal, 339 (3). pp. 525-531.

Oliver, Antony W and Kneale, G Geoff (1997) Preferential binding of the fd gene 5 protein to a structured form of the single-stranded DNA sequence d(GT5G4CT4C). Biochemical Society Transactions, 25 (4). S643.

Book Section

Oliver, Antony, Carpenter, ML and Kneale, GG (2001) Analysis of DNA-protein interactions by intrinsic fluorescence. In: Methods in Molecular Biology. Unset, pp. 491-502.

Carpenter, M L, Oliver, A W and Kneale, G G (2001) Circular dichroism for the analysis of protein-DNA interactions. In: Methods in Molecular Biology. Unset, pp. 503-510.

Patent

Cancer Research Technology Ltd; Collins, Ian; Caldwell, John J; Oliver, Antony W; Raynham, Tony M; Welsh, Emma J; Matijssen, Cornelius A J (2008) Therapeutic oxy-phenyl-aryl compounds and their use. PCT/GB2008/003586.

This list was generated on Mon Apr 24 14:22:51 2017 BST.