Items for Jeggo, Penny

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Article

Stiff, Tom, Casar Tena, Teresa, O'Driscoll, Mark, Jeggo, Penny A and Philipp, Melanie (2016) ATR promotes cilia signalling: links to developmental impacts. Human Molecular Genetics, 25 (8). pp. 1574-1587. ISSN 0964-6906

Baldock, Robert A, Day, Matthew, Wilkinson, Oliver J, Cloney, Ross, Jeggo, Penelope A, Oliver, Antony W, Watts, Felicity Z and Pearl, Laurence H (2015) ATM localization and heterochromatin repair depend on Direct Interaction of the 53BP1-BRCT2 domain with γH2AX. Cell Reports, 13 (10). pp. 2081-2089. ISSN 2211-1247

Woodbine, Lisa, Haines, Jackie, Coster, Margaret, Barazzuol, Lara, Ainsbury, Elizabeth, Sienkiewicz, Zenon and Jeggo, Penny (2015) The rate of X-ray-induced DNA double-strand break repair in the embryonic mouse brain is unaff ected by exposure to 50 Hz magnetic fi elds. International Journal of Radiation Biology, 91 (6). pp. 495-499. ISSN 0955-3002

Jeggo, Penny A, Pearl, Laurence H and Carr, Antony M (2015) DNA repair, genome stability and cancer: a historical perspective. Nature Reviews Cancer, 16 (1). pp. 35-42. ISSN 1474-175X

Jeggo, Penny A and Lobrich, Markus (2015) How cancer cells hijack DNA double-strand break repair pathways to gain genomic instability. Biochemical Journal, 471 (1). pp. 1-11. ISSN 0264-6021

Barazzuol, Lara, Rickett, Nicole, Ju, Limei and Jeggo, Penny A (2015) Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells. Journal of Cell Science, 128 (19). pp. 3597-3606. ISSN 0021-9533

Alagoz, Meryem, Katsuki, Yoko, Ogiwara, Hideaki, Ogi, Tomoo, Shibata, Atsushi, Kakarougkas, Andreas and Jeggo, Penny (2015) SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells. Nucleic Acids Research, 43 (16). pp. 7931-7944. ISSN 0305-1048

Guo, Chaowan, Nakazawa, Yuka, Woodbine, Lisa, Björkman, Andrea, Shimada, Mayuko, Fawcett, Heather, Jia, Nan, Ohyama, Kaname, Li, Tao-Sheng, Nagayama, Yuji, Mitsutake, Norisato, Pan-Hammarström, Qiang, Gennery, Andrew R, Lehmann, Alan R, Jeggo, Penny A and Ogi, Tomoo (2015) XRCC4 deficiency in human subjects causes a marked neurological phenotype but no overt immunodeficiency. Journal of Allergy and Clinical Immunology, 136 (4). pp. 1007-1017. ISSN 0091-6749

Saha, Shreya, Woodbine, Lisa, Haines, Jacqueline, Coster, Margaret, Ricket, Nicole, Barazzuol, Lara, Ainsbury, Elizabeth, Sienkiewicz, Zenon and Jeggo, Penny (2014) Increased apoptosis and DNA double-strand breaks in the embryonic mouse brain in response to very low-dose X-rays but not 50 Hz magnetic fields. Journal of the Royal Society Interface, 11 (100). p. 20140783. ISSN 1742-5689

Kakarougkas, Andreas, Ismail, Amani, Chambers, Anna, Riballo, Queti, Herbert, Alex, Kunzel, Julia, Lobrich, Markus, Jeggo, Penny and Downs, Jessica (2014) Requirement for PBAF in transcriptional repression and repair at DNA breaks in actively transcribed regions of chromatin. Molecular Cell, 55 (5). pp. 723-732. ISSN 1097-2765

Woodbine, Lisa, Gennery, Andrew R and Jeggo, Penny A (2014) Reprint of “The clinical impact of deficiency in DNA non-homologousend-joining”. DNA Repair, 17. pp. 9-20. ISSN 1568-7864

Kakarougkas, A and Jeggo, P A (2014) DNA DSB repair pathway choice: an orchestrated handover mechanism. British Journal of Radiology, 87 (1035). p. 20130685. ISSN 0007-1285

Shibata, Atsushi, Moiani, Davide, Arvai, Andrew S, Perry, Jefferson, Harding, Shane M, Genois, Marie-Michelle, Maity, Ranjan, van Rossum-Fikkert, Sari, Kertokalio, Aryandi, Romoli, Filipo, Ismail, Amani, Ismalaj, Ermal, Petricci, Elena, Neale, Matthew J, Bristow, Robert G, Masson, Jean-Yves, Wyman, Claire, Jeggo, Penny and Tainer, John A (2014) DNA double-strand break repair pathway shoice is directed by distinct MRE11 nuclease activities. Molecular Cell, 53 (1). pp. 7-18. ISSN 1097-2765

Barton, Olivia, Naumann, Steffen C, Diemer-Biehs, Ronja, Kunzel, Julia, Steinlage, Monika, Conrad, Sandro, Makharashvili, Nodar, Wang, Jiadong, Feng, Lin, Lopez, Bernard S, Paull, Tanya T, Chen, Junji, Jeggo, Penny A and Löbrich, Markus (2014) Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1. Journal of Cell Biology, 206 (7). pp. 877-894. ISSN 0021-9525

Shibata, Atsushi, Moiani, Davide, Arvai, Andrew S, Perry, Jefferson, Harding, Shane M, Genoise, Marie-Michelle, Maity, Ranjan, van Rossum-Fikkert, Sari, Kertokalio, Aryandi, Romoli, Filippo, Ismail, Amani, Ismalaj, Ermal, Neale, Matthew J, Bristow, Robert G, Masson, Jean-Yves, Wyman, Claire, Jeggo, Penny A, Tainer, John A and Petricci, Elena (2013) DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities. Molecular Cell, 53 (1). pp. 7-18. ISSN 1097-2765

Lee, Pamela P, Woodbine, Lisa, Gilmour, Kimberly C, Bibi, Shahnaz, Cale, Catherine M, Amrolia, Persios J, Veys, Paul A, Davies, E Graham, Jeggo, Penny A and Jones, Alison (2013) The many faces of Artemis-deficient combined immunodeficiency — two patients with DCLRE1C mutations and a systematic literature review of genotype–phenotype correlation. Clinical Immunology, 149 (3B). pp. 464-474. ISSN 1521-6616

Woodbine, Lisa, Neal, Jessica A, Sasi, Nanda-Kumar, Shimada, Mayuko, Deem, Karen, Coleman, Helen, Dobyns, William B, Ogi, Tomoo, Meek, Katheryn, Davies, E Graham and Jeggo, Penny A (2013) PRKDC mutations in a SCID patient with profound neurological abnormalities. Journal of Clinical Investigation, 123 (7). pp. 2969-2980. ISSN 0021-9738

Stiff, Tom, Alagoz, Meryem, Alcantara, Diana, Outwin, Emily, Brunner, Han G, Bongers, Ernie M H F, O'Driscoll, Mark and Jeggo, Penny A (2013) Deficiency in origin licensing proteins impairs cilia formation: implications for the aetiology of meier-gorlin syndrome. PLoS genetics, 9 (3). e1003360. ISSN 1553-7404

Kakarougkas, Andreas, Ismail, Amani, Katsuki, Yoko, Freire, Raimundo, Shibata, Atsushi and Jeggo, Penny A (2013) Co-operation of BRCA1 and POH1 relieves the barriers posed by 53BP1 and RAP80 to resection. Nucleic Acids Research, 41 (22). pp. 10298-10311. ISSN 0305-1048

Kakarougkas, Andreas, Ismail, Amani, Klement, Karolin, Goodarzi, Aaron A, Conrad, Sandro, Freire, Raimundo, Shibata, Atsushi, Lobrich, Markus and Jeggo, Penny A (2013) Opposing roles for 53BP1 during homologous recombination. Nucleic Acids Research, 41 (21). pp. 9719-9731. ISSN 0305-1048

Pernot, Eileen, Hall, Janet, Baatout, Sarah, Benotmane, Mohammed Abderrafi, Blanchardon, Eric, Bouffler, Simon, El Saghire, Houssein, Gomolka, Maria, Guertler, Anne, Harms-Ringdahl, Mats, Jeggo, Penny and et al., (2012) Ionizing radiation biomarkers for potential use in epidemiological studies. Mutation Research/Reviews in Mutation Research, 751 (2). pp. 258-286. ISSN 1383-5742

Murray, Johanne M, Stiff, Tom and Jeggo, Penny A (2012) DNA double-strand break repair within heterochromatic regions. Biochemical Society Transactions, 40 (1). pp. 173-178. ISSN 0300-5127

Ogi, Tomoo, Walker, Sarah, Stiff, Tom, Hobson, Emma, Limsirichaikul, Siripan, Carpenter, Gillian, Prescott, Katrina, Suri, Mohnish, Byrd, Philip J, Matsuse, Michiko, Mitsutake, Norisato, Nakazawa, Yuka, Vasudevan, Pradeep, Barrow, Margaret, Stewart, Grant S, Taylor, A Malcolm R, O'Driscoll, Mark and Jeggo, Penny A (2012) Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome. PLoS Genetics, 8 (11). e1002945. ISSN 1553-7390

Goodarzi, Aaron A, Kurka, Thomas and Jeggo, Penelope A (2011) KAP-1 phosphorylation regulates CHD3 nucleosome remodeling during the DNA double-strand break response. Nature Structural and Molecular Biology, 18 (7). pp. 831-839. ISSN 1545-9993

Bicknell, Louise S, Walker, Sarah, Klingseisen, Anna, Stiff, Tom, Leitch, Andrea, Kerzendorfer, Claudia, Martin, Carol-Anne, Yeyati, Patricia, Al Sanna, Nouriya, Bober, Michael, Johnson, Diana, Wise, Carol, Jackson, Andrew P, O'Driscoll, Mark and Jeggo, Penny A (2011) Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome. Nature Genetics, 43 (4). pp. 350-355. ISSN 1061-4036

Gatz, Susanne A, Ju, Limei, Gruber, Ralph, Hoffmann, Eva, Carr, Antony M, Wang, Zhao-Qi, Liu, Cong and Jeggo, Penny A (2011) Requirement for DNA Ligase IV during Embryonic Neuronal Development. Journal of Neuroscience, 31. pp. 10088-100100.

Shibata, A, Conrad, S, Birraux, J, Geuting, V, Barton, O, Ismail, A, Kakarougkas, A, Meek, K, Taucher-Scholz, G, Lobrich, M and Jeggo, P (2011) Factors determining DNA double-strand break repair pathway choice in G2 phase. EMBO Journal, 30 (6). pp. 1079-1092. ISSN 0261-4189

Jeggo, Penny (2010) The role of the DNA damage response mechanisms after low-dose radiation exposure and a consideration of potentially sensitive individuals. Radiation Research, 174 (6b). pp. 825-832. ISSN 0033-7587

Woodbine, Lisa, Grigoriadoub, Sofia, Goodarzi, Aaron A, Riballo, Enriqueta, Tape, Christopher, Oliver, Antony W, van Zelm, Menno C, Buckland, Matthew S, Davies, E Graham, Pearl, Laurence H and Jeggo, Penny A (2010) An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity. DNA Repair, 9 (9). pp. 1003-1010. ISSN 1568-7864

Deckbar, Dorothee, Stiff, Thomas, Kock, Barbara, Reis, Caroline, Löbrich, Markus and Jeggo, Penny (2010) The limitations of the G1-S checkpoint. Cancer Research, 70 (11). pp. 4412-4421. ISSN 0008-5472

Löser, Dana A., Shibata, Atsushi, Shibata, Akiko K ., Woodbine, Lisa J., Jeggo, Penny A. and Chalmers, Anthony J. (2010) Sensitization to Radiation and Alkylating Agents by Inhibitors of Poly(ADP-ribose) Polymerase Is Enhanced in Cells Deficient in DNA Double-Strand Break Repair. Molecular Cancer Therapeutics, 9 (6). pp. 1775-1787. ISSN 1535-7163

Lee, Ji-Hoon, Goodarzi, A.A., Jeggo, P.A. and Paull, Tanya T. (2010) 53BP1 promotes ATM activity through direct interactions with the MRN complex. EMBO Journal, 3. pp. 574-585. ISSN 0261-4189

Lobrich, Markus, Shibata, Atsushi, Beucher, Andrea, Fisher, Anna, Esminger, Michael, Goodarzi, Aaron A, Barton, Olivia and Jeggo, Penny A (2010) γH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization. Cell Cycle, 9 (4). pp. 662-669. ISSN 1538-4101

Noon, Angela T, Shibata, Atsushi, Rief, Nicole, Lobrich, Markus, Stewart, Grant S, Jeggo, Penelope A and Goodarzi, Aaaron A (2010) 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair. Nature Cell Biology, 12 (2). pp. 177-184. ISSN 1465-7392

Jeggo, Penny and Lavin, Martin F (2009) Cellular Radiosensitivity: How much better do we understand it? International Journal of Radiation Biology, 85 (12). pp. 1061-1081. ISSN 0955-3002

Beucher, Andrea, Birraux, Julie, Tchouandong, Leopoldine, Barton, Olivia, Shibata, Atsushi, Conrad, Sandro, Goodarzi, Aaron A, Krempler, Andrea, Jeggo, Penny and Lo¨brich, Markus (2009) ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2. EMBO Journal, 28 (21). pp. 3413-3427. ISSN 0261-4189

Jeggo, Peggy A. (2009) Risks from low dose/dose rate radiation: what an understanding of DNA damage response mechanisms can tell us. Health Physics, 97 (5). pp. 416-425. ISSN 0017-9078

Covo, Shay, de Villartay, Jean-Pierre, Jeggo, Penny A and Livneh, Zvi (2009) Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells. Nucleic Acids Research, 37 (20). pp. 6737-6745. ISSN 0305-1048

Nijnik, Anastasia, Dawson, Sara, Woodbine, Lisa, Visetnoi, Supawan, Bennett, Sophia, Jones, Margaret, Turner, Gareth D, Jeggo, Penelope A, Goodnow, Christopher C and Cornall, Richard J (2009) Impaired lymphocyte development and antibody class switching and increased malignancy in a murine model of DNA ligase IV syndrome. Journal of Clinical Investigation, 119 (6). pp. 1696-1705. ISSN 00219738

Goodarzi, Aaron A, Noon, Angela T and Jeggo, Penny A (2009) The impact of heterochromatin on DSB repair. Biochemical Society Transactions, 37 (3). pp. 569-576. ISSN 03005127

Goodarzi, Aaron A, Noon, Angela T and Jeggo, Penny A (2009) The impact of heterochromatin on DSB repair. Biochemical Society Transactions, 37 (3). pp. 569-576. ISSN 0300-5127

Riballo, Enriqueta, Woodbine, Lisa, Stiff, Thomas, Walker, Sarah A., Goodarzi, Aaron A. and Jeggo, Penny A. (2009) XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation. Nucleic Acids Research, 37 (2). pp. 482-492. ISSN 0305-1048

Stiff, Thomas, Cerosaletti, K, Concannon, P, O'Driscoll, Mark and Jeggo, Penny (2008) Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1. Human Molecular Genetics, 17 (20). pp. 3247-3253. ISSN 09646906

Goodarzi, Aaron, Noon, A.T, Deckbar, D, Ziv, Y, Shiloh, Y, Löbrich, M and Jeggo, Penny (2008) ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Molecular Cell, 31 (2). pp. 167-77. ISSN 10972765

O'Driscoll, Mark and Jeggo, Penny (2008) The role of the DNA damage response pathways in brain development and microcephaly: insight from human disorders. DNA Repair, 7 (7). pp. 1039-1050. ISSN 15687864

O'Driscoll, Mark and Jeggo, Penny (2008) Cyclosporine A can induce DNA double strand breaks: implications for bone marrow transplantation regimens particularly for individuals with defective DNA repair. Bone Marrow Transplantation, 41 (11). pp. 983-989. ISSN 02683369

Griffith, Elen, Walker, Sarah, Martin, Carol-Anne, Vagnarelli, Paola, Stiff, Tom, Vernay, Bertrand, Al Sanna, Nouriya, Saggar, Anand, Hamel, Ben, Earnshaw, William C, Jeggo, Penny A, Jackson, Andrew P and O'Driscoll, Mark (2008) Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nature Genetics, 40 (2). pp. 232-235. ISSN 1061-4036

O'Driscoll, M and Jeggo, P.A. (2008) Cyclosporine A can induce DNA double strand breaks: implications for bone marrow transplantation regimens particularly for individuals with defective DNA repair. Bone Marrow Transplantation, 41 (11). pp. 983-989. ISSN 0268-3369

Griffith, E., Walker, S., Martin, C.A., Vagnarelli, P., Stiff, T., Vernay, B., Al Sanna, N., Saggar, A., Hamel, B., Earnshaw, W.C., Jeggo, P.A., Jackson, A.P. and O'Driscoll, M. (2008) Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nature Genetics, 40 (2). pp. 232-236. ISSN 1061-4036

Griffith, E, Walker, Sarah, Stiff, Thomas, Martin, C-A, Vagnarelli, P, Vernay, B, Sanna, N.A, Saggar, A, Hamel, B, Earnshaw, W.C, Jeggo, Penny, Jackson, A.P and O'Driscoll, Mark (2008) Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nature Genetics, 40 (2). pp. 232-236. ISSN 10614036

Goodarzi, A.A., Noon, A.T., Deckbar, D., Ziv, Y., Shiloh, Y., Lobrich, M. and Jeggo, P.A. (2008) ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin. Molecular Cell, 31 (2). pp. 167-177. ISSN 1097-4164

Kegel, P., Riballo, M.E., Kuhne, M., Jeggo, P.A. and Lobrich, M. (2007) X-irradiation of cells on glass slides has a dose doubling impact. DNA Repair, 6 (11). pp. 1692-1697. ISSN 1568-7864

Krempler, A., Deckbar, D., Jeggo, P.A. and Lobrich, M. (2007) An Imperfect G(2)/M Checkpoint Contributes to Chromosome Instability Following Irradiation of S and G(2) Phase Cells. Cell Cycle, 6 (14). pp. 1682-1686. ISSN 1551-4005

O'Driscoll, Mark, Dobyns, William B, van Hagen, Johanna M and Jeggo, Penny A (2007) Cellular and clinical impact of haploinsufficiency for genes involved in ATR-signaling. American Journal of Human Genetics, 81 (1). pp. 77-86. ISSN 0002-9297

O'Driscoll, Mark, Dobyns, William B, van Hagen, Johanna M and Jeggo, Penny A (2007) Cellular and clinical impact of Haploinsufficiency for genes involved in ATR signaling. American Journal of Human Genetics, 81 (1). pp. 77-86. ISSN 0002-9297

Nijnik, Anastasia, Woodbine, Lisa, Marchetti, Caterina, Dawson, Sara, Lambe, Teresa, Liu, Cong, Rodrigues, Neil P, Crockford, Tanya L, Cabuy, Erik, Vindigni, Alessandro, Enver, Tariq, Bell, John I, Slijepcevic, Predrag, Goodnow, Christopher C, Jeggo, Penny A and Cornall, Richard J (2007) DNA repair is limiting for haematopoietic stem cells during ageing. Nature, 447, 686-690. Nature, 447. pp. 686-690. ISSN 0028-0836

Deckbar, D., Birraux, J., Krempler, A., Tchouandong, L., Beucher, A., Walker, S., Stiff, T, Jeggo, P.A. and Lobrich, M (2007) Chromosome breakage after G2 checkpoint release. Journal of Cell Biology, 176 (6). pp. 749-755. ISSN 0021-9525

Deckbar, Dorothee, Birraux, Julie, Krempler, Andrea, Tchouandong, Leopoldine, Beucher, Andrea, Walker, Sarah, Stiff, Thomas, Jeggo, Penny and Löbrich, Markus (2007) Chromosome breakage after G2 checkpoint release. Journal of Cell Biology, 176 (6). pp. 749-755. ISSN 0022-1007

Jeggo, P.A. and Lobrich, M. (2007) DNA double-strand breaks: their cellular and clinical impact? Oncogene, 26 (56). pp. 7717-7719. ISSN 1476-5594

Costantini, S., Woodbine, L., Andreoli, L., Jeggo, P. A. and Vindigni, A. (2007) Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK. DNA Repair. pp. 7711-11. ISSN 1568-7864

Costantini, Silvia, Woodbine, Lisa, Andreoli, Lucia, Jeggo, Penny A and Vindigni, Alessandro (2007) Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK. DNA Repair, 6(6). pp. 712-722. ISSN 1568-7864

Griffith, E., Walker, S., Martin, C.A., Vagnarelli, P., Stiff, T., Vernay, B., Al Sanna, A., Saggar, A., Hamel, B., Earnshaw, W.C., Jeggo, P.A., Jackson, A.P. and O'Driscoll, M. (2007) Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nature Genetics, 40 (2). pp. 232-236. ISSN 1546-1718 (Electronic)

Stiff, Thomas, Walker, Sarah, Cerosaletti, Karen, Goodarzi, Aaron, Petermann, Mylene Pamela, Concannon, Pat, O'Driscoll, Mark and Jeggo, Penny (2006) ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling. EMBO Journal, 25 (24). pp. 5775-5782. ISSN 0261-4189

Jeggo, Penny and Löbrich, Markus (2006) Radiation induced DNA damage responses. Radiation Protection Dosimetry, 122 (1-4). pp. 124-127. ISSN 1742-3406

Goodarzi, Aaron A, Yu, Yaping, Riballo, Enriqueta, Douglas, Pauline, Walker, Sarah A, Ye, Ruiqiong, Harer, Christine, Marchetti, Caterina, Morrice, Nick, Jeggo, Penny A and Lees-Miller, Susan P (2006) DNA-PK autophosphorylation facilitates Artemis endonuclease activity. EMBO Journal, 25 (16). pp. 3880-3889. ISSN 0261-4189

Marchetti, Caterina, Walker, Sarah A, Odreman, Federico, Vindigni, Alessandro, Doherty, Aidan J and Jeggo, Penny (2006) Identification of a novel motif in DNA ligases exemplified by DNA ligase IV. DNA Repair, 5 (7). pp. 788-798. ISSN 1568-7864

Alderton, Gemma K, Galbiati, Laura, Griffith, Elen, Surinya, Kathatrina H, Neitzel, Heidemarie, Jackson, Andrew P, Jeggo, Penny A and O'Driscoll, Mark (2006) Regulation of mitotic entry by microcephalin and its overlap with ATR signalling. Nature Cell Biology, 8 (7). pp. 725-733. ISSN 1465-7392

O'Driscoll, Mark and Jeggo, Penny (2006) The role of DSB repair-insights from human genetics. Nature Reviews Genetics, 7 (1). pp. 45-54. ISSN 1471-0056

Deckbar, D., Birraux, J., Krempler, A., Tchouandong, L., Beucher, A., Walker, S., Stiff, T., Jeggo, P.A. and Lobrich, M. (2006) Chromosome breakage after G2 checkpoint release. Cell Biology, 176 (6). pp. 749-755. ISSN 0022-1007

Jeggo, P. A. and Lobrich, M. (2006) Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stability. DNA Repair, 5 (9-10). pp. 1192-1198. ISSN 1568-7864

O'Driscoll, M., Jackson, A. P. and Jeggo, P. A. (2006) Microcephalin: A Causal Link Between Impaired Damage Response Signalling and Microcephaly. Cell Cycle, 5 (20). pp. 2339-2344. ISSN 1551-4005

O'Driscoll, Mark, Jackson, Andrew and Jeggo, Penny (2006) Microcephalin: A Causal Link Between Impaired Damage Response Signalling and Microcephaly. Cell Cycle, 5(20). pp. 2339-2344. ISSN 1551-4005

Evans, Paul M, Woodbine, Lisa, Riballo, Enriquetta, Gennery, Andrew R, Hubank, Michael and Jeggo, Penny A (2006) Radiation-induced delayed cell death in a hypomorphic Artemis cell line. Human Molecular Genetics, 15 (8). pp. 1303-1311. ISSN 0964-6906

Alderton, G. K., Galbiati, L., Griffith, E., Surinya, K. H., Neitzel, H., Jackson, A. P., Jeggo, P. A. and O'Driscoll, M. (2006) Regulation of mitotic entry by microcephalin and its overlap with ATR signalling. Nature Cell Biology. pp. 725-733. ISSN 1465-7392

O'Driscoll, M. and Jeggo, P. A. (2006) The role of double-strand break repair - insights from human genetics. Nature Reviews Genetics, 7 (1). pp. 45-54. ISSN 1471-0056

O'Driscoll, Mark and Jeggo, Penny A (2006) The role of double-strand break repair - insights from human genetics. Nature Reviews Genetics, 7(1). pp. 45-54. ISSN 1471-0056

Stiff, Thomas, Reis, Caroline, Alderton, Gemma K, Woodbine, Lisa, O'Driscoll, Mark and Jeggo, Penny A (2005) Nbs1 is required for ATR-dependent phosphorylation events. EMBO Journal, 24 (1). pp. 199-208. ISSN 0261-4189

Cabuy, E., Newton, C., Joksic, G., Woodbine, L., Koller, B., Jeggo, P. A. and Slijepcevic, P. (2005) Accelerated telomere shortening and telomere abnormalities in radiosensitive cell lines. Radiation Research, 164 (1). pp. 53-62. ISSN 0033-7587

Cabuy, E, Newton, C, Joksic, G, Woodbine, L, Koller, B, Jeggo, P A and Slijepcevic, P (2005) Accelerated telomere shortening and telomere abnormalities in radiosensitive cell lines. Radiation Research, 164 (1). pp. 53-62. ISSN 0033-7587

Jeggo, P. A. and Lobrich, M. (2005) Artemis links ATM to double strand breaking rejoining. Cell Cycle, 4. pp. 359-362. ISSN 1551-4005

Jeggo, P A and Lobrich, M (2005) Artemis links ATM to double strand breaking rejoining. Cell Cycle, 4(3). pp. 359-362. ISSN 1551-4005

Gennery, Andrew R., Slatter, Mary A., Bhattacharya, Arpita, Jeggo, Penny A., Abinun, Mario, Flood, Terence J. and Cant, Andrew J. (2005) Bone Marrow Transplantation for Nijmegan Breakage Syndrome. Journal of Pediatric Hematology/Oncology, 27 (4). p. 239. ISSN 1077-4114

Lobrich, M. and Jeggo, P. A. (2005) Harmonising the response to DSBs: a new string in the ATM bow. DNA Repair, 7. pp. 749-759. ISSN 1568-7864

Jeggo, Penny A and Löbrich, Markus (2005) Harmonising the response to DSBs: a new string in the ATM bow. DNA Repair, 4(7). pp. 749-759. ISSN 1568-7864

Kysela, B., Chovanec, M and Jeggo, P. A. (2005) Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation i the presence of histone H1. Proceedings of the National Academy of Sciences, 102. pp. 1877-1882. ISSN 1091-6490

Kysela, Boris, Chovanec, Miroslav and Jeggo, Penny A (2005) Phosphorylation of linker histones by DNA-dependent protein kinase is required for DNA ligase IV-dependent ligation i the presence of histone H1. Proceedings of the National Academy of Sciences, 102 (6). pp. 1877-1882. ISSN 1091-6490

Lobrich, M. and Jeggo, P. A. (2005) The two edges of the ATM sword: Co-operation between repair and checkpoint functions. Radiotherapy and Oncology, 76. pp. 112-118. ISSN 0167-8140

Löbrich, Markus and Jeggo, Penny A (2005) The two edges of the ATM sword: Co-operation between repair and checkpoint functions. Radiotherapy and Oncology, 76 (2). pp. 112-118. ISSN 0167-8140

Riballo, Enriqueta, Kühne, Martin, Rief, Nicole, Doherty, Aidan, Smith, Graeme C M, Recio, Marı́a-José, Reis, Caroline, Dahm, Kirsten, Fricke, Andreas, Krempler, Andrea, Parker, Antony R, Jackson, Stephen P, Gennery, Andrew, Jeggo, Penny A and Löbrich, Markus (2004) A Pathway of Double-Strand Break Rejoining Dependent upon ATM, Artemis, and Proteins Locating to ¿-H2AX Foci. Molecular Cell, 16 (5). pp. 715-724. ISSN 1097-2765

Gennery, A.R, Slatter, M.A., Bhattacharya, A, Barge, D, Haigh, S, O'Driscoll, Mark, Coleman, R, Abinun, M, Flood, T.J, Cant, A.J and Jeggo, Penny (2004) The clinical and biological overlap between Nijmegen Breakage syndrome and Fanconi Anemia. Clinical Immunology, 113 (2). pp. 214-219. ISSN 1521-6616

O'Driscoll, Mark, Gennery, AR, Seidel, J, Concammon, P and Jeggo, Penny (2004) An Overview of three new disorders associated with genetic instability: LIG4 syndrome, RS-SCID and ATR-Seckel syndrome. DNA Repair, 3 (8-9). pp. 1227-1235. ISSN 15687864

Stiff, Thomas, O'Driscoll, Mark, Rief, N, Iwabuchi, K, Lobrich, M and Jeggo, Penny (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation. Cancer Research, 64 (7). pp. 2390-2396. ISSN 00085472

Stiff, Thomas, Shtivelman, E, Jeggo, Penny and Kysela, B (2004) AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation. DNA Repair, 3 (3). pp. 245-256. ISSN 15687864

Stiff, T., Shtivelman, E., Jeggo, P. and Kysela, B. (2004) AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV mediated double stranded ligation. DNA Repair, 3. pp. 245-256. ISSN 1568-7864

Stiff, Thomas, Shtivelman, Emma, Jeggo, Penny, Kysela, Boris and Unset (2004) AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV mediated double stranded ligation. DNA Repair, 3(3). pp. 245-256. ISSN 1568-7864

Stiff, T., O'Driscoll, M., Rief, N., Iwabuchi, K., Lobrich, M. and Jeggo, P. A. (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX following exposure to ioninsing radiation. Cancer Research, 64. pp. 2390-2396. ISSN 0008-5472

Stiff, Tom, O'Driscoll, Mark, Rief, Nicole, Iwabuchi, Kuniyoshi, Löbrich, Markus and Jeggo, Penny A (2004) ATM and DNA-PK function redundantly to phosphorylate H2AX following exposure to ioninsing radiation. Cancer Research, 64(7). pp. 2390-2396. ISSN 0008-5472

Girard, Pierre-Marie, Kysela, Boris, Harer, Christine J., Doherty, Aidan J. and Jeggo, Penny A. (2004) Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms. Human Molecular Genetics, 13 (20). pp. 2369-76. ISSN 0964-6906

Girard, Pierre-Marie, Kysela, Boris, Härer, Christine J, Doherty, Aidan J and Jeggo, Penny A (2004) Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms. Human Molecular Genetics, 13 (20). pp. 2369-2376. ISSN 0964-6906

Izsvak, Z., Stuwe, E. E., Fiedler, D., Katzer, A., Jeggo, P. A. and Ivics, Z. (2004) Healing the wounds inflicted by Sleeping Beauty transposition by double-strand break repair in mammalian somatic cells. Molecular Cell, 13. pp. 279-290. ISSN 1097-2765

Izsvák, Zsuzsanna, Stüwe, Eva E, Fiedler, Dora, Katzer, Andrea, Jeggo, Penny A and Ivics, Zoltán (2004) Healing the wounds inflicted by Sleeping Beauty transposition by double-strand break repair in mammalian somatic cells. Molecular Cell, 13(2). pp. 279-290. ISSN 1097-2765

Jeggo, P. A. (2004) Non-Homologous end joining. Encyclopedia of Biological Chemistry, 3. pp. 66-70. ISSN 0-12-443710-9

Alderton, G. K., Joenje, H., Varon, R., Borglum, A. D., Jeggo, P. A. and O'Driscoll, M. (2004) Seckel syndrome exhibits cellular features demonstrating defects in the ATR signalling pathway. Human Molecular Genetics, 13. pp. 3127-3138. ISSN 1460-2083

Alderton, Gemma K, Joenje, Hans, Varon, Raymonda, Børglum, Anders D, Jeggo, Penny A and O'Driscoll, Mark (2004) Seckel syndrome exhibits cellular features demonstrating defects in the ATR signalling pathway. Human Molecular Genetics, 13(24). pp. 3127-3138. ISSN 0964-6906

Gennery, A.R., Slatter, M.A., Bhattacharya, A., Barge, D., Haigh, S., O'Driscoll, M., Coleman, R., Abinun, M., Flood, T.J., Cant, A.J. and Jeggo, P.A. (2004) The clinical and biological overlap between nijmegen breakage syndrome and fanconi anaemia. Clinical Immunology, 113. pp. 214-219. ISSN 1521-6616

Gennery, A R, Slatter, M A, Bhattacharya, A, Barge, D, Haigh, S, O'Driscoll, M, Coleman, R, Abinun, M, Flood, T J, Cant, A J and Jeggo, P A (2004) The clinical and biological overlap between nijmegen breakage syndrome and fanconi anaemia. Clinical Immunology, 113(2). pp. 214-219. ISSN 1521-6616

Kuhne, M., Riballo, E., Rief, N., Rothkamm, K., Jeggo, P. A. and Lobrich, M. (2004) A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Research, 64 (2). pp. 500-508. ISSN 0008-5472

Kuhne, Martin, Riballo, Enriqueta, Rief, Nicole, Rothkamm, Kai, Jeggo, Penny A and Löbrich, Markus (2004) A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity. Cancer Research, 64 (2). pp. 500-508. ISSN 0008-5472

Collis, S. J., DeWeese, T. L., Jeggo, P. A. and Parker, A. R. (2004) The life and death of DNA-PK. Oncogene, 24. pp. 949-961. ISSN 1476-5594

Collis, Spencer J, DeWeese, Theodore L, Jeggo, Penny A and Parker, Antony R (2004) The life and death of DNA-PK. Oncogene, 24(6). pp. 949-961. ISSN 1476-5594

O'Driscoll, M., Gennery, A. R., Seidel, J, Concannon, P. and Jeggo, P. A. (2004) An overview of three disorders associated with genetic instability: LIG4 syndrom, RS-SCID and ATR-Seckel syndrome. DNA Repair, 3. pp. 1227-1235. ISSN 1568-7864

O'Driscoll, M, Gennery, A R, Seidel, J, Concannon, P and Jeggo, P A (2004) An overview of three disorders associated with genetic instability: LIG4 syndrom, RS-SCID and ATR-Seckel syndrome. DNA Repair, 3(8-9). pp. 1227-1235. ISSN 1568-7864

Riballo, E., Kuhne, M., Rief, N., Doherty, A. J., Smith, G. C. M., Recio, M-J., Reis, C., Dahm, K., Fricke, A., Krempler, A., Parker, A. R., Jackson, S. P., Gennery, A. R., Jeggo, P. A. and Lobrich, M. (2004) A pathway of double strand break rejoining dependent upon ATM, Artemis and proteins locating to g-H2AX foci. Molecular Cell, 16. pp. 715-724. ISSN 1097-2765

Iwabuchi, K., Basu, B. P., Kysela, B., Kurihara, T., Shibata, M., Guan, D., Cao, Y., Hamada, T., Imamura, K., Jeggo, P. A., Date, T. and Doherty, A. J. (2003) Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. Journal of Biological Chemistry, 278 (38). pp. 36487-36495. ISSN 0021-9258

Iwabuchi, Kuniyoshi, Basu, Balaka Piku, Kysela, Boris, Kurihara, Takayuki, Shibata, Masao, Guan, Deyu, Cao, Yongheng, Hamada, Tomio, Imamura, Kouji, Jeggo, Penny A, Date, Takayasu and Doherty, Aidan J (2003) Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. Journal of Biological Chemistry, 278 (38). pp. 36487-36495. ISSN 0021-9258

O'Driscoll, Mark and Jeggo, Penny A (2003) Clinical impact of ATR checkpoint signalling failure in humans. Cell Cycle, 2 (3). pp. 194-195.

O'Driscoll, Mark, Ruiz-Perez, Victor L, Woods, C Geoffrey, Jeggo, Penny A and Goodship, Judith A (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nature Genetics, 33. pp. 497-501. ISSN 1061-4036

O'Driscoll, M. and Jeggo, P. A. (2003) Clinical Impact of ATR Checkpoint Signalling Failure in Humans. Cell Cycle, 2 (3). 194-195.. ISSN 1551-4005

Smith, J., Riballo, E., Kysela, B., Baldeyron, C., Manolis, K., Masson, C., Lieber, M. R., Papadopoulo, D. and Jeggo, P. (2003) Impact of DNA ligase IV on the fidelity of end joining in human cells. Nucleic Acids Research, 31. pp. 2157-2167. ISSN 0305-1048

Smith, Julianne, Riballo, Enriqueta, Kysela, B, Baldeyron, Celine, Manolis, Kostas, Masson, Christel, Lieber, Michael R, Papadopoulo, Dora and Jeggo, Penny (2003) Impact of DNA ligase IV on the fidelity of end joining in human cells. Nucleic Acids Research, 31(8). pp. 2157-2167. ISSN 0305-1048

Kysela, Boris, Doherty, Aidan J, Chovanec, Miroslav, Stiff, Thomas, Ameer-Beg, Simon M, Vojnovic, Borivoj, Girard, Pierre-Marie and Jeggo, Penny A (2003) Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule. Journal of Biological Chemistry, 278 (25). pp. 22466-22474. ISSN 0021-9258

Dai, Y, Kysela, B, Hanakahi, L A, Manolis, K, Riballo, E, Stumm, M, Harville, T O, West, S C, Oettinger, M A and Jeggo, P A (2003) Non-homologous end joining and V(D)J recombination require an additional factor. Proceedings of the National Academy of Sciences, 100 (5). pp. 2462-2467. ISSN 1091-6490

Doherty, Aidan, Kysela, Boris, Jeggo, Penny, Iwabuchi, K, Basu, BP and Kurihara, T (2003) p53-binding protein 1 (53BP1) binds to DNA at IR damage-induced foci and promotes DNA double-strand break repair. Journal of Biological Chemistry, 278. pp. 36487-36495. ISSN 0021-9258

O'Driscoll, M., Ruiz-Perez, V. L., Woods, C. G., Jeggo, P. A. and Goodship, J. A. (2003) A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome. Nature Genetics, 33. pp. 497-501. ISSN 1061-4036

O'Driscoll, M, Ruiz-Peres, V L, Woods, C G, Jeggo, P A and Goodship, J A (2003) A splicing mutation affecting expression of ataxia-telangiectasis and Rad3-related protein (ATR) results in Seckel syndrome. Nature Genetics, 33. pp. 497-501.

Foray, Nicolas, Marot, Didier, Gabriel, Anastasia, Randrianarison, Voahangy, Carr, Antony M, Perricaudet, Michel, Ashworth, Alan and Jeggo, Penny (2003) A subset of ATM- and ATR-dependent phosphorylation events requires the BRCA1 protein. EMBO Journal, 22 (11). pp. 2860-2871. ISSN 0261-4189

Roddam, P, Rollinson, S, O'Driscoll, M, Jeggo, P, Jack, A and Morgan, G (2002) Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombination. Journal of Medical Genetics, 39 (12). pp. 900-905.

Weller, Geoffery R, Kysela, Boris, Roy, Rajat, Tonkin, Louise M, Scanlan, Elizabeth, Della, Marina, Devine, Susanne Krogh, Day, Jonathan P, Wilkinson, Adam, d'Adda di Fagagna, Fabrizio, Devine, Kevin M, Bowater, Richard P, Jeggo, Penny A, Jackson, Stephen P and Doherty, Aidan J (2002) Identification of a DNA nonhomologous end-joining complex in bacteria. Science, 297. pp. 1686-1689. ISSN 0036-8075

O'Driscoll, Mark and Jeggo, Penny (2002) Immunological disorders and DNA Repair. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 509(1-. pp. 109-126. ISSN 0027-5107

Hirao, A., Cheung, A., Duncan, G., Girard, P-M., Elia, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., de Stanchina, E., Bristow, R. G., Suda, T., Lowe, S. W., Jeggo, P. A., Elledge, S. J. and Mak, T. E. (2002) Chk2 is a tumour suppressor that regulates apoptosis in both an ataxia telangiectasia mutad (ATM)-dependent and an ATM-independent manner. Molecular and Cellular Biology, 22. pp. 6521-6532. ISSN 0270-7306

Hirao, Atsushi, Cheung, Alison, Duncan, Gordon, Girard, Pierre-Marie, Elia, Andrew J, Wakeham, Andrew, Okada, Hitoshi, Sarkissian, Talin, Wong, Jorge A, Sakai, Takashi, de Stanchina, Elisa, Bristow, Robert G, Suda, Toshio, Lowe, Scott W, Jeggo, Penny A, Elledge, Stephen J and Mak, Tak W (2002) Chk2 is a tumour suppressor that regulates apoptosis in both an ataxia telangiectasia mutad (ATM)-dependent and an ATM-independent manner. Molecular and Cellular Biology, 22(18). pp. 6521-6532. ISSN 0270-7306

Foray, N., Marot, D., Randrianarison, V., Venezia, N. D., Picard, D., Perricaudet, M., Favaudon, V. and Jeggo, P. (2002) Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Molecular and Cellular Biology, 22 (12). 4020-4032.. ISSN 0270-7306

Foray, Nicolas, Marot, Didier, Randrianarison, Voahangy, Venezia, Nicole Dalla, Picard, Didier, Perricaudet, Michel, Favaudon, Vincent and Jeggo, Penny (2002) Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Molecular and Cellular Biology, 22(12). 4020-4032.. ISSN 0270-7306

Roddam, P. L., Rollinson, S., O'Driscoll, M., Jeggo, P. A., Jack, A. and Morgan, G. J. (2002) Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class-switch recombination. Journal of Medical Genetics, 39. pp. 900-905. ISSN 1468-6244

Jeggo, P. A. and O'Neill, P (2002) The Greek goddess, Artemis, reveals the secrets of her cleavage. DNA Repair, 67. pp. 1-7. ISSN 1568-7864

Jeggo, Penny and O'Neill, Peter (2002) The Greek goddess, Artemis, reveals the secrets of her cleavage. DNA Repair, 1(9). pp. 771-777. ISSN 1568-7864

O'Driscoll, M. and Jeggo, P. (2002) Immunological disorders and DNA Repair. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 509 ((1-2)). pp. 109-126. ISSN 0027-5107

Girard, P-M., Riballo, E., Begg, A., Waugh, A. and Jeggo, P. A. (2002) Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene, 21. pp. 4191-4199. ISSN 0950-9232

Girard, P M, Riballo, E, Begg, A C, Waugh, A and Jeggo, P A (2002) Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest. Oncogene, 21(27). pp. 4191-4199. ISSN 1476-5594

Jeggo, P. A. (2002) The fidelity of repair radiation damage. Radiation Protection Dosimetry, 99. pp. 117-122. ISSN 1742-3406

Jeggo, Penny (2002) The fidelity of repair radiation damage. Radiation Protection Dosimetry, 99 (1-4). pp. 117-122. ISSN 01448420

O'Driscoll, M., Cerosaletti, K. M., Girard, P-M., Dai, Y., Stumm, M., Kysela, B., Hirsch, B., Gennery, A., Palmer, S.E., Seidel, J., Gatti, R. A., Varon, R., Oettinger, M. A., Sperling, K., Jeggo, P. A. and Concannon, P. (2001) DNA Ligase IV mutations identified in patients exhibiting development delay and immunodeficiency. Molecular Cell, 8 (6). pp. 1175-1185. ISSN 1097-2765

O'Driscoll, Mark, Cerosaletti, Karen M, Girard, Pierre-M, Dai, Yan, Stumm, Markus, Kysela, Boris, Hirsch, Betsy, Gennery, Andrew, Palmer, Susan E, Seidel, Jörg, Gatti, Richard A, Varon, Raymonda, Oettinger, Marjorie A, Neitzel, Heidemarie, Jeggo, Penny A and Concannon, Patrick (2001) DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency. Molecular Cell, 8 (6). pp. 1175-1185. ISSN 1097-2765

Manolis, Kostas G, Nimmo, Elaine R, Hartsuiker, Edgar, Carr, Antony M, Jeggo, Penny A and Allshire, Robin C (2001) Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe. EMBO Journal, 20. pp. 210-221. ISSN 0261-4189

Riballo, Enriqueta, Doherty, Aidan J, Dai, Yan, Stiff, Thomas, Oettinger, Marjorie A, Jeggo, Penny A and Kysela, Boris (2001) Cellular and biochemical impact of a mutation in DNA ligase IV conferring clinical radiosensitivity. Journal of Biological Chemistry, 276. pp. 31124-31132. ISSN 0021-9258

O'Driscoll, Mark, Cerosaletti, Karen M, Girard, Pierre-M, Dai, Yan, Stumm, Markus, Kysela, Boris, Hirsch, Betsy, Gennery, Andrew, Palmer, Susan E, Seidel, Jörg, Gatti, Richard A, Varon, Raymonda, Oettinger, Marjorie A, Neitzel, Heidemarie, Jeggo, Penny A and Concannon, Patrick (2001) DNA Ligase IV mutations identified in patients exhibiting development delay and immunodeficiency. Molecular Cell, 8. pp. 1175-1185.

Jeggo, P. A. and Concannon, P. (2001) Immune diversity and genomic stability: opposite goals but similar paths. Journal of Photochemistry and Photobiology B: Biology, 65 (2-3). pp. 88-96. ISSN 1011-1344

Jeggo, Penny A and Concannon, Patrick (2001) Immune diversity and genomic stability: opposite goals but similar paths. Journal of Photochemistry and Photobiology B: Biology, 65(2-3. pp. 88-96. ISSN 1011-1344

Girard, P M, Foray, N, Stumm, M, Waugh, A, Riballo, E, Maser, R S, Phillips, W P, Petrini, J, Arlett, C F and Jeggo, P A (2000) Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. Cancer Research, 60. 4881 - 4888. ISSN 0008-5472

Riballo, E, Critchlow, S E, Teo, S-H, Doherty, A J, Priestley, A, Broughton, B, Kysela, B, Beamish, H, Plowman, N, Arlett, C F, Lehmann, A R, Jackson, S P and Jeggo, P A (1999) Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient. Current Biology, 9 (13). 699 - 702. ISSN 0960-9822

Singleton, B K, Torres-Arzayus, M I, Rottinghaus, ST, Taccioli, G E and Jeggo, P A (1999) The C Terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit. Molecular and Cellular Biology, 19(5). 3267 - 3277. ISSN 0270-7306

Blunt, Tracy, Gell, David, Fox, Margaret, Taccioli, Guillermo E, Lehmann, Alan R, Jackson, Stephen P and Jeggo, Penny A (1996) Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the i scid mouse. Proceedings of the National Academy of Sciences of the United States of America, 93. 10285 - 10290. ISSN 0027-8424

Book Section

O'Driscoll, Mark and Jeggo, Penny (2009) Introduction to the DNA repair and methylation defects. In: Primary Immunodeficiency Diseases. A Molecular and Genetic Approach. Oxford University Press.

Jeggo, P. A. (2005) Genomic Instability in cancer development. In: Nigg, E. A. (ed.) Genome Instability. Springer, Netherlands, pp. 175-197. ISBN 978-1-4020-3764-1

Jeggo, Penny (2005) Genomic Instability in cancer development. In: Nigg, Erich A (ed.) Genome Instability in Cancer Development. Advances in Experimental Medicine and Biology, 570 . Springer, Netherlands, pp. 175-197. ISBN 9781402037634

Conference or Workshop Item

Jeggo, Penny (2009) Mechanisms conferring sensitivity to low dose radiation exposure and consideration of potentially sensitivie individuals. In: Late health effects of ionizing radiation: bridging the experimental and epidemiological divide, 4-6 May 2009, Georgetown University, Washington D.C..

This list was generated on Thu Apr 27 04:15:22 2017 BST.