Article

Maina, Mahmoud B, Al-Hilaly, Youssra K, Oakley, Sebastian, Burra, Gunasekhar, Khanom, Tahmida, Biasetti, Luca, Mengham, Kurtis, Marshall, Karen, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2022) Dityrosine cross-links are present in alzheimer's disease-derived Tau Oligomers and Paired Helical Filaments (PHF) which Promotes the stability of the PHF-core Tau (297–391) in vitro. Journal of Molecular Biology, 434 (19). a167785 1-14. ISSN 0022-2836

Biasetti, Luca, Rey, Stephanie, Fowler, Milena, Ratnayaka, Arjuna, Fennell, Kate, Smith, Catherine, Marshall, Karen, Hall, Catherine, Vargas-Caballero, Mariana, Serpell, Louise and Staras, Kevin (2022) Elevated amyloid beta disrupts the nanoscale organization and function of synaptic vesicle pools in hippocampal neurons. Cerebral Cortex. pp. 1-14. ISSN 1047-3211

Lyu, Chen, Da Vela, Stefano, Al-Hilaly, Youssra, Marshall, Karen E, Thorogate, Richard, Svergun, Dmitri, Serpell, Louise C, Pastore, Annalisa and Hanger, Diane P (2021) The disease associated Tau35 fragment has an increased propensity to aggregate compared to full-length Tau. Frontiers in Molecular Biosciences, 8. a779240 1-13. ISSN 2296-889X

Marshall, Karen E, Vadukul, Devkee M, Staras, Kevin and Serpell, Louise C (2020) Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway. Cellular and Molecular Life Sciences, 77. pp. 5031-5043. ISSN 1420-682X

Oakley, Sebastian S, Maina, Mahmoud B, Marshall, Karen E, Al-Hilaly, Youssra K, Harrington, Charlie R, Wischik, Claude M and Serpell, Louise C (2020) Tau filament self-assembly and structure: tau as a therapeutic target. Frontiers in Neurology, 11. p. 590754. ISSN 1664-2295

Vadukul, Devkee M, Maina, Mahmoud, Franklin, Hannah, Nardecchia, Astrid, Serpell, Louise C and Marshall, Karen E (2020) Internalisation and toxicity of amyloid-β 1-42 are influenced by its conformation and assembly state rather than size. FEBS Letters, 594 (21). pp. 3490-3503. ISSN 0014-5793

Pollack, Saskia j, Trigg, Jasmine, Khanom, Tahmida, Biasetti, Luca, Marshall, Karen E, Al-Hilaly, Youssra K, Rickard, Janet E, Harrington, Charles R, Wischik, Claude M and Serpell, Louise C (2020) Paired helical filament-forming region of tau (297–391) influences endogenous tau protein and accumulates in acidic compartments in human neuronal cells. Journal of Molecular Biology, 432 (17). pp. 4891-4907. ISSN 0022-2836

Vadukul, Devkee M, Gbajumo, Oyinkansola, Marshall, Karen E and Serpell, Louise C (2017) Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid-β 1-42. FEBS Letters, 591 (5). pp. 822-830. ISSN 0014-5793

Marshall, Karen E, Vadukul, Devkee M, Dahal, Liza, Theisen, Alina, Fowler, Milena W, Al-Hilaly, Youssra, Ford, Lenzie, Kemenes, György, Day, Iain J, Staras, Kevin and Serpell, Louise (2016) A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration. Scientific Reports, 6 (1). a30182. ISSN 2045-2322

Marshall, Karen E, Marchante, Ricardo, Xue, Wei-Feng and Serpell, Louise C (2014) The relationship between amyloid structure and cytotoxicity. Prion, 8 (2). pp. 5-4. ISSN 1933-6896

Marshall, Karen, Morris, Kyle L, Charlton, Deborah, O’Reilly, Nicola, Lewis, Laurence, Walden, Helen and Serpell, Louise C (2011) Hydrophobic, aromatic and electrostatic interactions play a central role in amyloid fibril formation. Biochemistry, 50 (12). pp. 2061-2071. ISSN 0006-2960

Tamamis, Phanourios, Adler-Abramovich, Lihi, Reches, Meital, Marshall, Karen, Sikorski, Pawel, Serpell, Louise, Gazit, Ehud and Archontis, Georgios (2009) Self-Assembly of Phenylalanine Oligopeptides: Insights from Experiments and Simulations. Biophysical Journal, 96 (12). pp. 5020-5029. ISSN 0006-3495

Marshall, Karen E and Serpell, Louise C (2009) The structural integrity of β-sheet assembly. Biochemical Society Transactions, 37 (4). pp. 671-676. ISSN 0300-5127

Marshall, Karen E and Serpell, Louise C (2009) Structural integrity of ß-sheet assembly. Biochemical Society Transactions, 37. pp. 671-676. ISSN 0300-5127

Thesis

Marshall, Karen Elizabeth (2010) Structural polymorphism of amyloidogenic peptides. Doctoral thesis (DPhil), University of Sussex.