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Ottaviani, Silvia, Stebbing, Justin, Frampton, Adam E, Zagorac, Sladjana, Krell, Jonathan, de Giorgio, Alexander, Trabulo, Sara M, Nguyen, Van T M, Magnani, Luca, Feng, Hugang, Giovannetti, Elisa, Funel, Nicola, Gress, Thomas, Jiao, Long, Lombardo, Ylenia, Lemoine, Nicholas R, Heeschen, Christopher and Castellano, Leandro (2018) TGF-ß induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression. Nature Communications, 9 (1845). pp. 1-18. ISSN 2041-1723

Begum, S, Yiu, A, Stebbing, J and Castellano, L (2018) Novel tumour suppressive protein encoded by circular RNA, circ-SHPRH, in glioblastomas. Oncogene. ISSN 1476-5594

Frampton, Adam E, Prado, Mireia Mato, López-Jiménez, Elena, Fajardo-Puerta, Ana Belen, Jawad, Zaynab A R, Lawton, Phillip, Giovannetti, Elisa, Habib, Nagy A, Castellano, Leandro, Stebbing, Justin, Krell, Jonathan and Jiao, Long R (2018) Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden. Oncotarget, 9 (27). pp. 19006-19013. ISSN 1949-2553

Macdougall, Claire E, Wood, Elizabeth G, Loschko, Jakob, Scagliotti, Valeria, Cassidy, Féaron C, Robinson, Mark E, Feldhahn, Niklas, Castellano, Leandro, Voisin, Mathieu-Benoit, Marelli-Berg, Federica, Gaston-Massuet, Carles, Charalambous, Marika and Longhi, M Paula (2018) Visceral adipose tissue immune homeostasis is regulated by the crosstalk between adipocytes and dendritic cell subsets. Cell metabolism, 27 (3). 588-601.e4. ISSN 1932-7420

Harrod, A, Fulton, J, Nguyen, V T M, Periyasamy, M, Ramos-Garcia, L, Lai, C-F, Metodieva, G, de Giorgio, A, Williams, R L, Santos, D B, Gomez, P J, Lin, M-L, Metodiev, M V, Stebbing, J, Castellano, L, Magnani, L, Coombes, R C, Buluwela, L and Ali, S (2017) Genomic modelling of the ESR1 Y537S mutation for evaluating function and new therapeutic approaches for metastatic breast cancer. Oncogene, 36 (16). pp. 2286-2296. ISSN 1476-5594

Boulianne, Bryant, Robinson, Mark E, May, Philippa C, Castellano, Leandro, Blighe, Kevin, Thomas, Jennifer, Reid, Alistair, Müschen, Markus, Apperley, Jane F, Stebbing, Justin and Feldhahn, Niklas (2017) Lineage-specific genes are prominent DNA damage hotspots during leukemic transformation of B cell precursors. Cell reports, 18 (7). pp. 1687-1698. ISSN 2211-1247

Castellano, Leandro, Dabrowska, Aleksandra, Pellegrino, Loredana, Ottaviani, Silvia, Cathcart, Paul, Frampton, Adam E, Krell, Jonathan and Stebbing, Justin (2017) Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR. Nucleic acids research, 45 (8). pp. 4401-4412. ISSN 1362-4962

Miller, Helen C, Frampton, Adam E, Malczewska, Anna, Ottaviani, Silvia, Stronach, Euan A, Flora, Rashpal, Kaemmerer, Daniel, Schwach, Gert, Pfragner, Roswitha, Faiz, Omar, Kos-Kudła, Beata, Hanna, George B, Stebbing, Justin, Castellano, Leandro and Frilling, Andrea (2016) MicroRNAs associated with small bowel neuroendocrine tumours and their metastases. Endocrine-related cancer, 23 (9). pp. 711-726. ISSN 1479-6821

Pardo, Olivier E, Castellano, Leandro, Munro, Catriona E, Hu, Yili, Mauri, Francesco, Krell, Jonathan, Lara, Romain, Pinho, Filipa G, Choudhury, Thameenah, Frampton, Adam E, Pellegrino, Loredana, Pshezhetskiy, Dmitry, Wang, Yulan, Waxman, Jonathan, Seckl, Michael J and Stebbing, Justin (2016) miR-515-5p controls cancer cell migration through MARK4 regulation. EMBO reports, 17 (4). pp. 570-584. ISSN 1469-3178

Jacob, Jimmy, Favicchio, Rosa, Karimian, Negin, Mehrabi, Maryam, Harding, Victoria, Castellano, Leandro, Stebbing, Justin and Giamas, Georgios (2016) LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5. Cancer Letters, 372 (1). pp. 137-146. ISSN 0304-3835

Krell, Jonathan, Stebbing, Justin, Carissimi, Claudia, Dabrowska, Aleksandra F, de Giorgio, Alexander, Frampton, Adam E, Harding, Victoria, Fulci, Valerio, Macino, Giuseppe, Colombo, Teresa and Castellano, Leandro (2016) TP53 regulates miRNA association with AGO2 to remodel the miRNA-mRNA interaction network. Genome Research, 26 (3). pp. 331-341. ISSN 1549-5469

Nguyen, Van T M, Barozzi, Iros, Faronato, Monica, Lombardo, Ylenia, Steel, Jennifer H, Patel, Naina, Darbre, Philippa, Castellano, Leandro, Győrffy, Balázs, Woodley, Laura, Meira, Alba, Patten, Darren K, Vircillo, Valentina, Periyasamy, Manikandan, Ali, Simak, Frige, Gianmaria, Minucci, Saverio, Coombes, R Charles and Magnani, Luca (2015) Differential epigenetic reprogramming in response to specific endocrine therapies promotes cholesterol biosynthesis and cellular invasion. Nature communications, 6 (10044). ISSN 2041-1723

Roca-Alonso, L, Castellano, L, Mills, A, Dabrowska, A F, Sikkel, M B, Pellegrino, L, Jacob, J, Frampton, A E, Krell, J, Coombes, R C, Harding, S E, Lyon, A R and Stebbing, J (2015) Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis. Cell Death & Disease, 6. e1754. ISSN 2041-4889

Castellano, Leandro, Rizzi, Ermanno, Krell, Jonathan, Di Cristina, Manlio, Galizi, Roberto, Mori, Ayako, Tam, Janis, De Bellis, Gianluca, Stebbing, Justin, Crisanti, Andrea and Nolan, Tony (2015) The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNA. BMC genomics, 16. p. 100. ISSN 1471-2164

Tan, Geok Chin, Chan, Elcie, Molnar, Attila, Sarkar, Rupa, Alexieva, Diana, Isa, Ihsan Mad, Robinson, Sophie, Zhang, Shuchen, Ellis, Peter, Langford, Cordelia F, Guillot, Pascale V, Chandrashekran, Anil, Fisk, Nick M, Castellano, Leandro, Meister, Gunter, Winston, Robert M, Cui, Wei, Baulcombe, David and Dibb, Nick J (2014) 5' isomiR variation is of functional and evolutionary importance. Nucleic acids research, 42 (14). pp. 9424-9435. ISSN 1362-4962

Krell, Jonathan, Frampton, Adam E, Mirnezami, Reza, Harding, Victoria, De Giorgio, Alex, Roca Alonso, Laura, Cohen, Patrizia, Ottaviani, Silvia, Colombo, Teresa, Jacob, Jimmy, Pellegrino, Loredana, Buchanan, Gordon, Stebbing, Justin and Castellano, Leandro (2014) Growth arrest-specific transcript 5 associated snoRNA levels are related to p53 expression and DNA damage in colorectal cancer. PloS one, 9 (6). e98561. ISSN 1932-6203

Frampton, Adam E, Castellano, Leandro, Colombo, Teresa, Giovannetti, Elisa, Krell, Jonathan, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, Funel, Niccola, Gall, Tamara M H, De Giorgio, Alexander, Pinho, Filipa G, Fulci, Valerio, Britton, David J, Ahmad, Raida, Habib, Nagy A, Coombes, R Charles, Harding, Victoria, Knösel, Thomas, Stebbing, Justin and Jiao, Long R (2014) MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression. Gastroenterology, 146 (1). 268-277.e18. ISSN 0016-5085

Pinho, Filipa G, Frampton, Adam E, Nunes, Joao, Krell, Jonathan, Alshaker, Heba, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, de Giorgio, Alexander, Harding, Victoria, Waxman, Jonathan, Stebbing, Justin, Pchejetski, Dmitry and Castellano, Leandro (2013) Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation. Cancer research, 73 (19). pp. 5936-5948. ISSN 1538-7445

Pellegrino, Loredana, Stebbing, Justin, Braga, Vania M, Frampton, Adam E, Jacob, Jimmy, Buluwela, Lakjaya, Jiao, Long R, Periyasamy, Manikandan, Madsen, Chris D, Caley, Matthew P, Ottaviani, Silvia, Roca-Alonso, Laura, El-Bahrawy, Mona, Coombes, R Charles, Krell, Jonathan and Castellano, Leandro (2013) miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts. Nucleic Acids Research, 41 (10). pp. 5400-5412. ISSN 1362-4962

Castellano, Leandro and Stebbing, Justin (2013) Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues. Nucleic Acids Research, 41 (5). pp. 3339-3351. ISSN 0305-1048

Krell, Jonathan, Frampton, Adam E, Jacob, Jimmy, Pellegrino, Loredana, Roca-Alonso, Laura, Zeloof, Daniel, Alifrangis, Costi, Lewis, Jacqueline S, Jiao, Long R, Stebbing, Justin and Castellano, Leandro (2012) The clinico-pathologic role of microRNAs miR-9 and miR-151-5p in breast cancer metastasis. Molecular Diagnosis & Therapy, 16 (3). pp. 167-172. ISSN 1179-2000

Jiao, Long R, Frampton, Adam E, Jacob, Jimmy, Pellegrino, Loredana, Krell, Jonathan, Giamas, Georgios, Tsim, Nicole, Vlavianos, Panagiotis, Cohen, Patrizia, Ahmad, Raida, Keller, Andreas, Habib, Nagy A, Stebbing, Justin and Castellano, Leandro (2012) MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors. PloS ONE, 7 (2). e32068. ISSN 1932-6203

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Castellano, Leandro, Giamas, Georgios, Jacob, Jimmy, Coombes, R Charles, Lucchesi, Walter, Thiruchelvam, Paul, Barton, Geraint, Jiao, Long R, Wait, Robin, Waxman, Jonathan, Hannon, Gregory J and Stebbing, Justin (2009) The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proceedings of the National Academy of Sciences, 106 (37). pp. 15732-15737. ISSN 1091-6490

Giamas, Georgios, Castellano, Leandro, Feng, Qin, Knippschild, Uwe, Jacob, Jimmy, Thomas, Ross S, Coombes, R Charles, Smith, Carolyn L, Jiao, Long R and Stebbing, Justin (2009) CK1δ modulates the transcriptional activity of ERα via AIB1 in an estrogen-dependent manner and regulates ERα-AIB1 interactions. Nucleic Acids Research, 37 (9). pp. 3110-3123. ISSN 0305-1048

Apostolopoulos, Christos, Castellano, Leandro, Stebbing, Justin and Giamas, Georgios (2008) Bendamustine as a model for the activity of alkylating agents. Future Oncology, 4 (3). pp. 323-332. ISSN 1479-6694

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