Items for Giamas, Georgios

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Number of items: 47.

Article

Simon, Thomas, Gagliano, Teresa and Giamas, Georgios (2017) Direct effects of anti-angiogenic therapies on tumor cells: VEGF signaling. Trends in Molecular Medicine, 23 (3). pp. 282-292. ISSN 1471-4914

Wendler, F, Favicchio, R, Simon, T, Alifrangis, C, Stebbing, J and Giamas, G (2017) Extracellular vesicles swarm the cancer microenvironment: from tumor–stroma communication to drug intervention. Oncogene, 36 (7). pp. 877-884. ISSN 0950-9232

Favicchio, Rosy, Thepaut, Chloe, Zhang, Hua, Arends, Richard, Stebbing, Justin and Giamas, Georgios (2016) Strategies in functional proteomics: unveiling the pathways to precision oncology. Cancer Letters, 382 (1). pp. 86-94. ISSN 0304-3835

Wendler, Franz, Stamp, Gordon and Giamas, Georgios (2016) Tumor–stromal cell communication: small vesicles signal big changes. Trends in Cancer, 2 (7). pp. 326-329. ISSN 2405-8033

Angelopoulos, Nicos, Stebbing, Justin, Xu, Yichen, Giamas, Georgios and Zhang, Hua (2016) Proteome-wide dataset supporting functional study of tyrosine kinases in breast cancer. Data in Brief, 7. pp. 740-746. ISSN 2352-3409

Rampias, T, Favicchio, R, Stebbing, J and Giamas, G (2016) Targeting tumor-stroma crosstalk: the example of the NT157 inhibitor. Oncogene, 35 (20). pp. 2562-2564. ISSN 0950-9232

Nunes, Joao, Zhang, Hua, Angelopoulos, Nicos, Chhetri, Jyoti, Osipo, Clodia, Grothey, Arnhild, Stebbing, Justin and Giamas, Georgios (2016) ATG9A loss confers resistance to trastuzumab via c-Cbl mediated Her2 degradation. Oncotarget, 7 (19). pp. 27599-27612. ISSN 1949-2553

Jacob, Jimmy, Favicchio, Rosa, Karimian, Negin, Mehrabi, Maryam, Harding, Victoria, Castellano, Leandro, Stebbing, Justin and Giamas, Georgios (2016) LMTK3 escapes tumour suppressor miRNAs via sequestration of DDX5. Cancer Letters, 372 (1). pp. 137-146. ISSN 0304-3835

Xu, Yichen, Zhang, Hua, Nguyen, Van, Angelopoulos, Nikos, Nunes, Joao, Reid, Alistair, Buluwela, Laki, Magnani, Luca, Stebbing, Justin and Giamas, Georgios (2015) LMTK3 represses tumor suppressor-like genes through chromatin remodeling in breast cancer. Cell Reports, 12 (5). pp. 837-849. ISSN 2211-1247

Stebbing, Justin, Zhang, Hua, Xu, Yichen, Grothey, Arnhild, Ajuh, Paul, Angelopoulos, Nicos and Giamas, Georgios (2015) Reprogramming of the tyrosine kinase-regulated proteome in breast cancer by combined use of RNAi and SILAC quantitative proteomics. Molecular & cellular proteomics : MCP, 14. 2479-2492.. ISSN 1535-9484

Zhang, Hua, Angelopoulos, Nicos, Xu, Yichen, Grothey, Arnhild, Nunes, Joao, Stebbing, Justin and Giamas, Georgios (2015) Proteomic profile of KSR1-regulated signalling in response to genotoxic agents in breast cancer. Breast Cancer Research and Treatment, 151 (3). pp. 555-568. ISSN 0167-6806

Stebbing, J, Zhang, H, Xu, Y, Lit, L C, Green, A R, Grothey, A, Lombardo, Y, Periyasamy, M, Blighe, K, Zhang, W, Shaw, J A, Ellis, I O, Lenz, H J and Giamas, G (2015) KSR1 regulates BRCA1 degradation and inhibits breast cancer growth. Oncogene, 34 (16). pp. 2103-2114. ISSN 1476-5594

Benhaim, L, Zhang, W, Wakatsuki, T, Yang, D, Gerger, A, Bohanes, P, Paez, D, Loupakis, F, LaBonte, M J, Ning, Y, El-Khoueiry, R, Ladner, R, Wilson, P, Zhang, H, Giamas, G, Stebbing, J and Lenz, H J (2015) Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer. The Pharmacogenomics Journal, 15 (3). pp. 235-240. ISSN 1470-269X

Zhang, Hua, Stebbing, Justin and Giamas, Georgios (2015) The many-faced KSR1: a tumor suppressor in breast cancer. Oncoscience, 2 (8). pp. 669-670. ISSN 2331-4737

Zhang, Hua, Xu, Yichen, Papanastasopoulos, Panos, Stebbing, Justin and Giamas, Georgios (2014) Broader implications of SILAC-based proteomics for dissecting signaling dynamics in cancer. Expert Review of Proteomics, 11 (6). pp. 713-731. ISSN 1478-9450

Xu, Yichen, Zhang, Hua and Giamas, Georgios (2014) Targeting lemurs against cancer metastasis. Oncotarget, 5 (14). pp. 5192-5193. ISSN 1949-2553

Xu, Yichen, Zhang, Hua, Lit, Lei C, Grothey, Arnhild, Athanasiadou, Maria, Kiritsi, Marianna, Lombardo, Ylenia, Frampton, Adam E, Green, Andrew R, Ellis, Ian O, Ali, Simak, Lenz, Heinz-Josef, Thanou, Maya, Stebbing, Justin and Giamas, Georgios (2014) The kinase LMTK3 promotes invasion in breast cancer through GRB2-mediated induction of integrin β₁. Science signaling, 7 (330). ra58. ISSN 1937-9145

Stebbing, J, Lit, L C, Zhang, H, Darrington, R S, Melaiu, O, Rudraraju, B and Giamas, G (2014) The regulatory roles of phosphatases in cancer. Oncogene, 33 (8). pp. 939-953. ISSN 1476-5594

Winder, T, Giamas, G, Wilson, P M, Zhang, W, Yang, D, Bohanes, P, Ning, Y, Gerger, A, Stebbing, J and Lenz, H-J (2014) Insulin-like growth factor receptor polymorphism defines clinical outcome in estrogen receptor-positive breast cancer patients treated with tamoxifen. The Pharmacogenomics Journal, 14 (1). pp. 28-34. ISSN 1473-1150

Melaiu, Ombretta, Stebbing, Justin, Lombardo, Ylenia, Bracci, Elisa, Uehara, Norihisa, Bonotti, Alessandra, Cristaudo, Alfonso, Foddis, Rudy, Mutti, Luciano, Barale, Roberto, Gemignani, Federica, Giamas, Georgios and Landi, Stefano (2014) MSLN gene silencing has an anti-malignant effect on cell lines overexpressing mesothelin deriving from malignant pleural mesothelioma. PLoS one, 9 (1). e85935. ISSN 1932-6203

Stebbing, J, Filipović, A and Giamas, G (2013) Claudin-1 as a promoter of EMT in hepatocellular carcinoma. Oncogene, 32 (41). pp. 4871-4872. ISSN 0950-9232

Wakatsuki, Takeru, LaBonte, Melissa J, Bohanes, Pierre O, Zhang, Wu, Yang, Dongyun, Azuma, Mizutomo, Barzi, Afsaneh, Ning, Yan, Loupakis, Fotios, Saadat, Siamak, Volz, Nico, Stintzing, Sebastian, El-Khoueiry, Rita, Koizumi, Wasaburo, Watanabe, Masahiko, Shah, Manish, Stebbing, Justin, Giamas, Georgios and Lenz, Heinz-Josef (2013) Prognostic role of lemur tyrosine kinase-3 germline polymorphisms in adjuvant gastric cancer in Japan and the United States. Molecular Cancer Therapeutics, 12 (10). pp. 2261-2272. ISSN 1535-7163

Zhang, Hua, Koo, Chuay Yeng, Stebbing, Justin and Giamas, Georgios (2013) The dual function of KSR1: a pseudokinase and beyond. Biochemical Society Transactions, 41 (4). pp. 1078-82. ISSN 0300-5127

Stebbing, J, Filipovic, A, Lit, L C, Blighe, K, Grothey, A, Xu, Y, Miki, Y, Chow, L W, Coombes, R C, Sasano, H, Shaw, J A and Giamas, G (2013) LMTK3 is implicated in endocrine resistance via multiple signaling pathways. Oncogene, 32 (28). pp. 3371-3380. ISSN 0950-9232

Filipovic, Aleksandra, Stebbing, Justin and Giamas, Georgios (2013) Cancer stem cells - therapeutic targeting or therapy? The Lancet Oncology, 14 (7). pp. 579-580. ISSN 1474-5488

Lit, Lei Cheng, Scott, Susan, Zhang, Hua, Stebbing, Justin, Photiou, Andrew and Giamas, Georgios (2013) LATS2 is a modulator of estrogen receptor alpha. Anticancer Research, 33 (1). pp. 53-63. ISSN 0250-7005

Zhang, H, Xu, Y, Filipovic, A, Lit, L C, Koo, C-Y, Stebbing, J and Giamas, G (2013) SILAC-based phosphoproteomics reveals an inhibitory role of KSR1 in p53 transcriptional activity via modulation of DBC1. British Journal of Cancer, 109 (10). pp. 2675-2684. ISSN 1532-1827

Lombardo, Ylenia, Filipović, Aleksandra, Molyneux, Gemma, Periyasamy, Manikandan, Giamas, Georgios, Hu, Yunhui, Trivedi, Pritesh S, Wang, Jayson, Yagüe, Ernesto, Michel, Loren and Coombes, R Charles (2012) Nicastrin regulates breast cancer stem cell properties and tumor growth in vitro and in vivo. Proceedings of the National Academy of Sciences, 109 (41). pp. 16558-16563. ISSN 1091-6490

Zhang, Hua, Photiou, Andrew, Grothey, Arnhild, Stebbing, Justin and Giamas, Georgios (2012) The role of pseudokinases in cancer. Cellular Signalling, 24 (6). pp. 1173-1184. ISSN 0898-6568

Stebbing, Justin, Filipovic, Aleksandra, Ellis, Ian O, Green, Andrew R, D'Silva, Tanya Rapoz, Lenz, Heinz-Josef, Coombes, R Charles, Wang, Tingting, Lee, Soo-Chin and Giamas, Georgios (2012) LMTK3 expression in breast cancer: association with tumor phenotype and clinical outcome. Breast Cancer Research and Treatment, 132 (2). pp. 537-544. ISSN 0167-6806

Jiao, Long R, Frampton, Adam E, Jacob, Jimmy, Pellegrino, Loredana, Krell, Jonathan, Giamas, Georgios, Tsim, Nicole, Vlavianos, Panagiotis, Cohen, Patrizia, Ahmad, Raida, Keller, Andreas, Habib, Nagy A, Stebbing, Justin and Castellano, Leandro (2012) MicroRNAs targeting oncogenes are down-regulated in pancreatic malignant transformation from benign tumors. PloS ONE, 7 (2). e32068. ISSN 1932-6203

Filipović, A, Giamas, G and Stebbing, J (2011) The potential role of cyclooxygenase-2 (COX-2) during early breast cancer therapy. Annals of Oncology, 22 (8). pp. 1700-1702. ISSN 0923-7534

Stebbing, Justin, Filipović, Aleksandra and Giamas, Georgios (2011) Lemur tyrosine kinase-3 (LMTK3) in cancer and evolution. Oncotarget, 2 (6). pp. 428-9. ISSN 1949-2553

Giamas, Georgios, Filipović, Aleksandra, Jacob, Jimmy, Messier, Walter, Zhang, Hua, Yang, Dongyun, Zhang, Wu, Shifa, Belul Assefa, Photiou, Andrew, Tralau-Stewart, Cathy, Castellano, Leandro, Green, Andrew R, Coombes, R Charles, Ellis, Ian O, Ali, Simak, Lenz, Heinz-Josef and Stebbing, Justin (2011) Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nature Medicine, 17 (6). pp. 715-719. ISSN 1546-170X

Giamas, Georgios, Man, Yik L, Hirner, Heidrun, Bischof, Joachim, Kramer, Klaus, Khan, Kalimullah, Ahmed, Sharmeen S Lavina, Stebbing, Justin and Knippschild, Uwe (2010) Kinases as targets in the treatment of solid tumors. Cellular Signalling, 22 (7). pp. 984-1002. ISSN 0898-6568

Castellano, Leandro, Giamas, Georgios, Jacob, Jimmy, Coombes, R Charles, Lucchesi, Walter, Thiruchelvam, Paul, Barton, Geraint, Jiao, Long R, Wait, Robin, Waxman, Jonathan, Hannon, Gregory J and Stebbing, Justin (2009) The estrogen receptor-alpha-induced microRNA signature regulates itself and its transcriptional response. Proceedings of the National Academy of Sciences, 106 (37). pp. 15732-15737. ISSN 1091-6490

Giamas, Georgios, Castellano, Leandro, Feng, Qin, Knippschild, Uwe, Jacob, Jimmy, Thomas, Ross S, Coombes, R Charles, Smith, Carolyn L, Jiao, Long R and Stebbing, Justin (2009) CK1δ modulates the transcriptional activity of ERα via AIB1 in an estrogen-dependent manner and regulates ERα-AIB1 interactions. Nucleic Acids Research, 37 (9). pp. 3110-3123. ISSN 0305-1048

Mintz, Paul J, Habib, Nagy A, Jones, Louise J, Giamas, Georgios, Lewis, Jacqueline S, Bowen, Rebecca L, Coombes, R Charles and Stebbing, Justin (2008) The phosphorylated membrane estrogen receptor and cytoplasmic signaling and apoptosis proteins in human breast cancer. Cancer, 113 (6). pp. 1489-1495. ISSN 0008-543X

Brockschmidt, C, Hirner, H, Huber, N, Eismann, T, Hillenbrand, A, Giamas, G, Radunsky, B, Ammerpohl, O, Bohm, B, Henne-Bruns, D, Kalthoff, H, Leithäuser, F, Trauzold, A and Knippschild, U (2008) Anti-apoptotic and growth-stimulatory functions of CK1 delta and epsilon in ductal adenocarcinoma of the pancreas are inhibited by IC261 in vitro and in vivo. Gut, 57 (6). pp. 799-806. ISSN 0017-5749

Apostolopoulos, Christos, Castellano, Leandro, Stebbing, Justin and Giamas, Georgios (2008) Bendamustine as a model for the activity of alkylating agents. Future Oncology, 4 (3). pp. 323-332. ISSN 1479-6694

von Blume, J, Knippschild, Uwe, Dequiedt, Franck, Giamas, Georgios, Beck, Alexander, Auer, Alexandra, Van Lint, Johan, Adler, Guido and Seufferlein, Thomas (2007) Phosphorylation at Ser244 by CK1 determines nuclear localization and substrate targeting of PKD2. EMBO Journal, 26 (22). pp. 4619-4633. ISSN 0261-4189

Apostolopoulos, Christos, Giamas, Georgios and Stebbing, Justin (2007) Clinical significance of circulating tumor cells. Biomarkers in Medicine, 1 (3). pp. 341-342. ISSN 1752-0363

Giamas, Georgios, Hirner, Heidrun, Shoshiashvili, Levani, Grothey, Arnhild, Gessert, Susanne, Kühl, Michael, Henne-Bruns, Doris, Vorgias, Constantinos E and Knippschild, Uwe (2007) Phosphorylation of CK1δ: identification of Ser370 as the major phosphorylation site targeted by PKA in vitro and in vivo. Biochemical Journal, 406 (3). pp. 389-398. ISSN 0264-6021

Giamas, Georgios, Stebbing, Justin, Vorgias, Constantinos E and Knippschild, Uwe (2007) Protein kinases as targets for cancer treatment. Pharmacogenomics, 8 (8). pp. 1005-1016. ISSN 1462-2416

Wolff, Sonja, Stöter, Martin, Giamas, Georgios, Piesche, Matthias, Henne-Bruns, Doris, Banting, George and Knippschild, Uwe (2006) Casein kinase 1 delta (CK1delta) interacts with the SNARE associated protein snapin. FEBS Letters, 580 (27). pp. 6477-6484. ISSN 0014-5793

Knippschild, Uwe, Wolff, Sonja, Giamas, Georgios, Brockschmidt, Claas, Wittau, Mathias, Würl, Peter Uwe, Eismann, Thorsten and Stöter, Martin (2005) The role of the casein kinase 1 (CK1) family in different signaling pathways linked to cancer development. Onkologie, 28 (10). pp. 508-514. ISSN 0378-584X

Conference or Workshop Item

Gagliano, Teresa, Ditsiou, Angeliki, Grothey, Arnhild and Giamas, Georgios (2016) Human kinome siRNA screening to identify novel targets implicated in fibroblast-mediated triple negative breast cancer cells invasion. In: EACR conference series goodbye flat biology: models, mechanisms and microenvironment, 2 - 5 october 2016, Berlin.

This list was generated on Tue Dec 12 05:51:45 2017 GMT.