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Vaitsiankova, Alina, Burdova, Kamila, Sobol, Margarita, Gautam, Amit, Benada, Oldrich, Hanzlikova, Hana and Caldecott, Keith W (2022) PARP inhibition impedes the maturation of nascent DNA strands during DNA replication. Nature Structural and Molecular Biology, 29. pp. 329-338. ISSN 1545-9993
Adamowicz, Marek, Hailstone, Richard, Demin, Annie A, Komulainen, Emilia, Hanzlikova, Hana, Brazina, Jan, Gautam, Amit, Wells, Sophie E and Caldecott, Keith W (2021) XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair. Nature Cell Biology. ISSN 1465-7392
Demin, Annie A, Hirota, Kouji, Tsuda, Masataka, Adamowicz, Marek, Hailstone, Richard, Brazina, Jan, Gittens, William, Kalasova, Ilona, Shao, Zhengping, Zha, Shan, Sasanuma, Hiroyuki, Hanzlikova, Hana, Takeda, Shunichi and Caldecott, Keith W (2021) XRCC1 prevents toxic PARP1 trapping during DNA base excision repair. Molecular Cell, 81 (14). 3018-3030.e5. ISSN 1097-2765
Wu, Wei, Hill, Sarah E, Nathan, William J, Paiano, Jacob, Callen, Elsa, Wang, Dongpeng, Shinoda, Kenta, van Wietmarschen, Niek, Colón-Mercado, Jennifer M, Zong, Dali, De Pace, Raffaella, Shih, Han-Yu, Coon, Steve, Hanzlikova, Hana, Caldecott, Keith W and others, (2021) Neuronal enhancers are hotspots for DNA single-strand break repair. Nature, 593. pp. 440-444. ISSN 0028-0836
Komulainen, Emilia, Badman, Jack, Rey, Stephanie, Rulten, Stuart, Ju, Limei, Fennell, Kate, Kalasova, Ilona, Ilievova, Kristyna, McKinnon, Peter J, Hanzlikova, Hana, Staras, Kevin and Caldecott, Keith W (2021) Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures. EMBO Reports, 22 (5). a51851 1-12. ISSN 1469-221X
Hanzlikova, Hana, Prokhorova, Evgeniia, Krejcikova, Katerina, Cihlarova, Zuzana, Kalasova, Ilona, Kubovciak, Jan, Sachova, Jana, Hailstone, Richard, Brazina, Jan, Ghosh, Shereen, Cirak, Sebahattin, Gleeson, Joseph G, Ahel, Ivan and Caldecott, Keith W (2020) Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair. Nature Communications, 11 (1). a3391 1-13. ISSN 2041-1723
Kalasova, Ilona, Hanzlikova, Hana, Gupta, Neerja, Li, Yun, Altmüller, Janine, Reynolds, John J, Stewart, Grant S, Wollnick, Bernd, Yigit, Gökhan and Caldecott, Keith W (2019) Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ. Neurology Genetics, 5 (2). pp. 1-7. ISSN 2376-7839
Hanzlikova, Hana, Kalasova, Ilona, Demin, Annie A, Pennicott, Lewis E, Cihlarova, Zuzana and Caldecott, Keith W (2018) The importance of Poly(ADP-Ribose) Polymerase as a sensor of unligated Okazaki fragments during DNA replication. Molecular Cell, 71 (2). pp. 319-331. ISSN 1097-2765
Hanzlikova, Hana, Gittens, William, Krejcikova, Katerina, Zeng, Zhihong and Caldecott, Keith W (2017) Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin. Nucleic Acids Research, 45 (5). pp. 2546-2557. ISSN 1362-4962
Hoch, Nicolas C, Hanzlikova, Hana, Rulten, Stuart L, Tétreault, Martine, Komulainen, Emilia, Ju, Limei, Hornyak, Peter, Zeng, Zhihong, Gittens, William, Rey, Stephanie A, Staras, Kevin, Mancini, Grazia M S, McKinnon, Peter J, Wang, Zhao-Qi, Wagner, Justin D, Care4Rare Canada Consortium, , Yoon, Grace and Caldecott, Keith W (2017) XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia. Nature, 541. pp. 87-91. ISSN 0028-0836
Breslin, Claire, Hornyak, Peter, Ridley, Andrew, Rulten, Stuart L, Hanzlikova, Hana, Oliver, Antony W and Caldecott, Keith W (2015) The XRCC1 phosphate-binding pocket binds poly (ADP-ribose) and is required for XRCC1 function. Nucleic Acids Research, 43 (14). pp. 6934-6944. ISSN 0305-1048