Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report

Bozzali, Marco, Grassini, Alberto, Morana, Giovanni, Zotta, Michela, Cabras, Sara, Romagnolo, Alberto, Artusi, Carlo Alberto, Montalenti, Elisa, Rizzone, Mario Giorgio, Garbossa, Diego, Montanaro, Elisa, Cercignani, Mara and Lopiano, Leonardo (2021) Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report. Neurological Sciences, 42. pp. 2619-2623. ISSN 1590-1874

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Abstract

We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.

Item Type: Article
Keywords: COVID-19, Encephalitis, Epilepsy, Focal seizures with impaired awareness
Schools and Departments: Brighton and Sussex Medical School > Neuroscience
SWORD Depositor: Mx Elements Account
Depositing User: Mx Elements Account
Date Deposited: 18 May 2021 08:12
Last Modified: 17 Apr 2022 01:00
URI: http://sro.sussex.ac.uk/id/eprint/99217

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