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Large-scale remote fear conditioning: demonstration of associations with anxiety using the FLARe smartphone app

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Version 2 2023-06-12, 09:45
Version 1 2023-06-09, 23:10
journal contribution
posted on 2023-06-12, 09:45 authored by Thomas McGregor, Kirstin L Purves, Elena Constantinou, Johanna M P Baas, Tom J Barry, Ewan Carr, Michelle G Craske, Kathryn LesterKathryn Lester, Elisavet Palaiologou, Gerome Breen, Katherine S Young, Thalia C Eley
Objectives We aimed to examine differences in fear conditioning between anxious and nonanxious participants in a single large sample. Materials and methods We employed a remote fear conditioning task (FLARe) to collect data from participants from the Twins Early Development Study (n?=?1,146; 41% anxious vs. 59% nonanxious). Differences between groups were estimated for their expectancy of an aversive outcome towards a reinforced conditional stimulus (CS+) and an unreinforced conditional stimulus (CS-) during acquisition and extinction phases. Results During acquisition, the anxious group (vs. nonanxious group) showed greater expectancy towards the CS-. During extinction, the anxious group (vs. nonanxious group) showed greater expectancy to both CSs. These comparisons yielded effect size estimates (d?=?0.26–0.34) similar to those identified in previous meta-analyses. Conclusion The current study demonstrates that remote fear conditioning can be used to detect differences between groups of anxious and nonanxious individuals, which appear to be consistent with previous meta-analyses including in-person studies.

History

Publication status

  • Published

File Version

  • Published version

Journal

Depression and Anxiety

ISSN

1091-4269

Publisher

Wiley

Page range

1-12

Department affiliated with

  • Psychology Publications

Full text available

  • Yes

Peer reviewed?

  • Yes

Legacy Posted Date

2021-02-26

First Open Access (FOA) Date

2021-04-12

First Compliant Deposit (FCD) Date

2021-02-25

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