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The challenges of chronic pain and fatigue
journal contribution
posted on 2023-06-09, 22:56 authored by Jessica EcclesJessica Eccles, Kevin DaviesKevin DaviesIn this review, we explore the challenges of chronic pain and fatigue in clinical practice. Both pain and fatigue are common, troubling and frequently overlapping symptoms, and we describe both the clinical burden and the ‘clinical problem’. We explore commonly associated symptoms and possible pathological associations, including variant connective tissue (joint hypermobility), small fibre neuropathy, mast cell activation, dysregulated inflammatory and interoceptive processes, which may inform treatment targets. We suggest a multidisciplinary management approach.
Funding
Fibroduck Foundation - Donation to continue PF5661; G2725; FIBRODUCK FOUNDATION
Investigating the effects of mild inflammation on brain function in ME/CFS; G2485; ACTION FOR ME
Viscero-sensory processes and neural responses to inflammation: mechanisms of pain and fatigue in fibromyalgia; G1863; ARTHRITIS RESEARCH UK; 21194
History
Publication status
- Published
File Version
- Published version
Journal
Clinical MedicineISSN
1470-2118Publisher
Royal College of PhysiciansExternal DOI
Issue
1Volume
21Page range
19-27Department affiliated with
- BSMS Neuroscience Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2021-02-01First Open Access (FOA) Date
2022-01-22First Compliant Deposit (FCD) Date
2021-01-31Usage metrics
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