Reference%20Intervals%20for%20routine%20biochemical%20markers%20and%20body%20mass%20index%3B%20a%20study%20based%20on%20healthcare%20center%20database%20in%20northeastern%20Iran.pdf (460.96 kB)
Reference intervals for routine biochemical markers and body mass index: a study based on healthcare center database in northeastern Iran
journal contribution
posted on 2023-06-21, 06:01 authored by Hamideh Ghazizadeh, Mahdiyeh Yaghooti-Khorasani, Atieh Kamel Khodabandeh, Elahe Hasanzadeh, Toktam Sahranavard, Seyed Hamed Banihashem-Rad, Reza Zare-Feyzabadi, Mansoureh Sadat Ekhteraee-Toosi, Ensieh Akbarpour, Ameneh Timar, Maryam Mohammadi-Bajgiran, Reza Assaran-Darban, Ehsan Mosa Farkhany, Mohammad Reza Oladi, Gordon FernsGordon Ferns, Habibollah Esmaily, Majid Ghayour-MobarhanAge- and sex-specific reference intervals (RIs) for some biochemical tests may be useful for their interpretation, due to the variations in lifestyle and genetic, or ethnic factors. The aim of this study was to obtain RIs for some routine biochemical markers including a serum lipid profile, fasting blood glucose (FBG), aspartate and alanine aminotransferase (AST and ALT), uric acid, and body mass index (BMI) in subjects who attended primary healthcare centers. The large database of primary healthcare centers uses RIs to report results for children, adolescents, and young and old adults. RIs were obtained by using the indirect method, recommended by the CLSI Ep28-A3 guidelines. RIs for FBG, BMI, and serum lipid profile, including triglyceride, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol in people aged 18 to 120?years, were obtained without age/sex segmentation. RIs for serum AST, ALT, and uric acid were obtained without age segmentation, though these RIs were higher in males than females. The RIs for AST, ALT, and uric acid were higher in men, while the RIs for the other variables were similar in both sexes. This is the first study reporting the use of indirect RIs for BMI.
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- Published
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- Accepted version
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IUBMB LifeISSN
1521-6543Publisher
WileyExternal DOI
Department affiliated with
- Division of Medical Education Publications
Full text available
- Yes
Peer reviewed?
- Yes
Legacy Posted Date
2021-01-26First Open Access (FOA) Date
2022-01-01First Compliant Deposit (FCD) Date
2021-01-26Usage metrics
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