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Excess mortality in severe mental illness: 10-Year population-based cohort study rural Ethiopia
journal contribution
posted on 2023-06-09, 22:34 authored by Abe WassieAbe Wassie, Girmay Medhin, Derege Kebede, Atalay Alem, Anthony J Cleare, Martin Prince, Charlotte Hanlon, Teshome ShibreBackground Evidence on mortality in severe mental illness (SMI) comes primarily from clinical samples in high-income countries. Aims To describe mortality in people with SMI among a population cohort from a low-income country. Method We followed-up 919 adults (from 68 378 screened) with SMI over 10 years. Standardised mortality ratios (SMR) and years of life lost (YLL) as a result of premature mortality were calculated. Results In total 121 patients (13.2%) died. The overall SMR was twice that of the general population; higher for men and people with schizophrenia. Patients died about three decades prematurely, mainly from infectious causes (49.6%). Suicide, accidents and homicide were also common causes of death. Conclusions Mortality is an important adverse outcome of SMI irrespective of setting. Addressing common natural and unnatural causes of mortality are urgent priorities. Premature death and mortality related to self-harm should be considered in the estimation of the global burden of disease for SMI.
History
Publication status
- Published
Journal
British Journal of PsychiatryISSN
0007-1250Publisher
Cambridge University PressExternal DOI
Issue
4Volume
206Page range
289-296Event location
EnglandDepartment affiliated with
- Global Health and Infection Publications
Full text available
- No
Peer reviewed?
- Yes
Legacy Posted Date
2021-02-04Usage metrics
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