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Dynamics of shadow system of a singular Gierer-Meinhardt system on an evolving domain

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Version 2 2023-06-12, 09:31
Version 1 2023-06-09, 21:45
journal contribution
posted on 2023-06-12, 09:31 authored by Nikos I Kavallaris, Raquel Bareira, Anotida Madzvamuse
The main purpose of the current paper is to contribute towards the comprehension of the dynamics of the shadow system of a singular Gierer–Meinhardt model on an isotropically evolving domain. In the case where the inhibitor’s response to the activator’s growth is rather weak, then the shadow system of the Gierer–Meinhardt model is reduced to a single though non-local equation whose dynamics is thoroughly investigated throughout the manuscript. The main focus is on the derivation of blow-up results for this non-local equation, which can be interpreted as instability patterns of the shadow system. In particular, a diffusion-driven instability (DDI), or Turing instability, in the neighbourhood of a constant stationary solution, which then is destabilised via diffusion-driven blow-up, is observed. The latter indicates the formation of some unstable patterns, whilst some stability results of global-in-time solutions towards non-constant steady states guarantee the occurrence of some stable patterns. Most of the theoretical results are verified numerically, whilst the numerical approach is also used to exhibit the dynamics of the shadow system when analytical methods fail.

Funding

Unravelling new mathematics for 3D cell migration; G1438; LEVERHULME TRUST; RPG-2014-149

InCeM: Research Training Network on Integrated Component Cycling in Epithelial Cell Motility; G1546; EUROPEAN UNION

New predictive mathematical and computational models in experimental sciences; G1949; ROYAL SOCIETY; WM160017

History

Publication status

  • Published

File Version

  • Published version

Journal

Journal of Nonlinear Science

ISSN

0938-8974

Publisher

Springer

Issue

1

Volume

31

Page range

1-34

Article number

a5

Pages

33.0

Department affiliated with

  • Mathematics Publications

Full text available

  • No

Peer reviewed?

  • Yes

Legacy Posted Date

2020-10-05

First Open Access (FOA) Date

2021-01-18

First Compliant Deposit (FCD) Date

2020-10-02

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