Selective photoinduced reduction of nitroarenes to n-arylhydroxylamines

Kallitsakis, Michael G, Ioannou, Dimitris I, Terzidis, Michael A, Kostakis, George E and Lykakis, Ioannis N (2020) Selective photoinduced reduction of nitroarenes to n-arylhydroxylamines. Organic Letters, 22 (11). pp. 4339-4343. ISSN 1523-7060

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Abstract

We report the selective photoinduced reduction of nitroarenes to N-arylhydroxylamines. The present methodology facilitates this transformation in the absence of catalyst or additives and uses only light and methylhydrazine. This noncatalytic photoinduced transformation proceeds with a broad scope, excellent functional-group tolerance, and high yields. The potential of this protocol reflects on the selective and straightforward conversion of two general antibiotics, azomycin and chloramphenicol, to the bioactive hydroxylamine species.

Item Type: Article
Schools and Departments: School of Life Sciences > Chemistry
SWORD Depositor: Mx Elements Account
Depositing User: Mx Elements Account
Date Deposited: 22 May 2020 07:17
Last Modified: 27 May 2021 01:00
URI: http://sro.sussex.ac.uk/id/eprint/91350

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